Search | Virtual Health Library

1.

Proliferation at the heart of preadolescence.

Palpant, Nathan J; Murry, Charles E.

Cell ; 157(4): 765-7, 2014 May 08.

Article in English | MEDLINE | ID: mdl-24813600

2.

Inferring cell diversity in single cell data using consortium-scale epigenetic data as a biological anchor for cell identity.

Sun, Yuliangzi; Shim, Woo Jun; Shen, Sophie; Sinniah, Enakshi; Pham, Duy; Su, Zezhuo; Mizikovsky, Dalia; White, Melanie D; Ho, Joshua W K; Nguyen, Quan; Bodén, Mikael; Palpant, Nathan J.

Nucleic Acids Res ; 51(11): e62, 2023 06 23.

Article in English | MEDLINE | ID: mdl-37125641

3.

Organization of gene programs revealed by unsupervised analysis of diverse gene-trait associations.

Mizikovsky, Dalia; Naval Sanchez, Marina; Nefzger, Christian M; Cuellar Partida, Gabriel; Palpant, Nathan J.

Nucleic Acids Res ; 50(15): e87, 2022 08 26.

Article in English | MEDLINE | ID: mdl-35716123

4.

New Drug Targets and Preclinical Modelling Recommendations for Treating Acute Myocardial Infarction.

Cao, Yuanzhao; Redd, Meredith A; Fang, Chen; Mizikovsky, Dalia; Li, Xichun; Macdonald, Peter S; King, Glenn F; Palpant, Nathan J.

Heart Lung Circ ; 32(7): 852-869, 2023 Jul.

Article in English | MEDLINE | ID: mdl-37230806

5.

Therapeutic Inhibition of Acid-Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury.

Redd, Meredith A; Scheuer, Sarah E; Saez, Natalie J; Yoshikawa, Yusuke; Chiu, Han Sheng; Gao, Ling; Hicks, Mark; Villanueva, Jeanette E; Joshi, Yashutosh; Chow, Chun Yuen; Cuellar-Partida, Gabriel; Peart, Jason N; See Hoe, Louise E; Chen, Xiaoli; Sun, Yuliangzi; Suen, Jacky Y; Hatch, Robert J; Rollo, Ben; Xia, Di; Alzubaidi, Mubarak A H; Maljevic, Snezana; Quaife-Ryan, Gregory A; Hudson, James E; Porrello, Enzo R; White, Melanie Y; Cordwell, Stuart J; Fraser, John F; Petrou, Steven; Reichelt, Melissa E; Thomas, Walter G; King, Glenn F; Macdonald, Peter S; Palpant, Nathan J.

Circulation ; 144(12): 947-960, 2021 09 21.

Article in English | MEDLINE | ID: mdl-34264749

6.

Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations.

Nguyen, Quan H; Lukowski, Samuel W; Chiu, Han Sheng; Senabouth, Anne; Bruxner, Timothy J C; Christ, Angelika N; Palpant, Nathan J; Powell, Joseph E.

Genome Res ; 28(7): 1053-1066, 2018 07.

Article in English | MEDLINE | ID: mdl-29752298

7.

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.

Chong, James J H; Yang, Xiulan; Don, Creighton W; Minami, Elina; Liu, Yen-Wen; Weyers, Jill J; Mahoney, William M; Van Biber, Benjamin; Cook, Savannah M; Palpant, Nathan J; Gantz, Jay A; Fugate, James A; Muskheli, Veronica; Gough, G Michael; Vogel, Keith W; Astley, Cliff A; Hotchkiss, Charlotte E; Baldessari, Audrey; Pabon, Lil; Reinecke, Hans; Gill, Edward A; Nelson, Veronica; Kiem, Hans-Peter; Laflamme, Michael A; Murry, Charles E.

Nature ; 510(7504): 273-7, 2014 Jun 12.

Article in English | MEDLINE | ID: mdl-24776797

8.

Genetic Lineage Tracing of Sca-1⁺ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart.

Vagnozzi, Ronald J; Sargent, Michelle A; Lin, Suh-Chin J; Palpant, Nathan J; Murry, Charles E; Molkentin, Jeffery D.

Circulation ; 138(25): 2931-2939, 2018 12 18.

Article in English | MEDLINE | ID: mdl-29991486

9.

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction.

Redd, Meredith A; Yoshikawa, Yusuke; Khan, Nemat; Waqar, Maleeha; Saez, Natalie J; Outhwaite, Jennifer E; Russell, Jake S; Hanna, Amy D; Chiu, Han S; Er, Sing Yan; Butcher, Neville J; Mardon, Karine; Fraser, John F; Smythe, Mark L; Rash, Lachlan D; Thomas, Walter G; King, Glenn F; Reichelt, Melissa E; Palpant, Nathan J.

Eur Heart J ; 2023 Dec 14.

Article in English | MEDLINE | ID: mdl-38095341

10.

The ins and outs of cellular pH during cardiac ischemia.

Cao, Yuanzhao; Palpant, Nathan J.

J Mol Cell Cardiol ; 174: 133-134, 2023 Jan.

Article in English | MEDLINE | ID: mdl-36581136

11.

Defining the Fetal Gene Program at Single-Cell Resolution in Pediatric Dilated Cardiomyopathy.

Mehdiabadi, Neda R; Boon Sim, Choon; Phipson, Belinda; Kalathur, Ravi K R; Sun, Yuliangzi; Vivien, Celine J; Ter Huurne, Menno; Piers, Adam T; Hudson, James E; Oshlack, Alicia; Weintraub, Robert G; Konstantinov, Igor E; Palpant, Nathan J; Elliott, David A; Porrello, Enzo R.

Circulation ; 146(14): 1105-1108, 2022 10 04.

Article in English | MEDLINE | ID: mdl-36191067

12.

Inhibition of ß-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes.

Palpant, Nathan J; Pabon, Lil; Roberts, Meredith; Hadland, Brandon; Jones, Daniel; Jones, Christina; Moon, Randall T; Ruzzo, Walter L; Bernstein, Irwin; Zheng, Ying; Murry, Charles E.

Development ; 142(18): 3198-209, 2015 Sep 15.

Article in English | MEDLINE | ID: mdl-26153229

13.

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts.

Shiba, Yuji; Fernandes, Sarah; Zhu, Wei-Zhong; Filice, Dominic; Muskheli, Veronica; Kim, Jonathan; Palpant, Nathan J; Gantz, Jay; Moyes, Kara White; Reinecke, Hans; Van Biber, Benjamin; Dardas, Todd; Mignone, John L; Izawa, Atsushi; Hanna, Ramy; Viswanathan, Mohan; Gold, Joseph D; Kotlikoff, Michael I; Sarvazyan, Narine; Kay, Matthew W; Murry, Charles E; Laflamme, Michael A.

Nature ; 489(7415): 322-5, 2012 Sep 13.

Article in English | MEDLINE | ID: mdl-22864415

14.

The developmental origins and lineage contributions of endocardial endothelium.

Nakano, Atsushi; Nakano, Haruko; Smith, Kelly A; Palpant, Nathan J.

Biochim Biophys Acta ; 1863(7 Pt B): 1937-47, 2016 Jul.

Article in English | MEDLINE | ID: mdl-26828773

15.

Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development.

Palpant, Nathan J; Pabon, Lil; Rabinowitz, Jeremy S; Hadland, Brandon K; Stoick-Cooper, Cristi L; Paige, Sharon L; Bernstein, Irwin D; Moon, Randall T; Murry, Charles E.

Development ; 140(18): 3799-808, 2013 Sep.

Article in English | MEDLINE | ID: mdl-23924634

16.

Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1-Positive Cells in the Adult Mouse Heart.

Neidig, Lauren E; Weinberger, Florian; Palpant, Nathan J; Mignone, John; Martinson, Amy M; Sorensen, Daniel W; Bender, Ingrid; Nemoto, Natsumi; Reinecke, Hans; Pabon, Lil; Molkentin, Jeffery D; Murry, Charles E; van Berlo, Jop H.

Circulation ; 138(25): 2960-2962, 2018 12 18.

Article in English | MEDLINE | ID: mdl-30566022

17.

High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms.

Kramer, Simon; Kotapati, Charan; Cao, Yuanzhao; Fry, Bryan G; Palpant, Nathan J; King, Glenn F; Cardoso, Fernanda C.

Toxicon X ; 21: 100184, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38389571

18.

Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm.

Wu, Zhixuan; Shen, Sophie; Mizikovsky, Dalia; Cao, Yuanzhao; Naval-Sanchez, Marina; Tan, Siew Zhuan; Alvarez, Yanina D; Sun, Yuliangzi; Chen, Xiaoli; Zhao, Qiongyi; Kim, Daniel; Yang, Pengyi; Hill, Timothy A; Jones, Alun; Fairlie, David P; Pébay, Alice; Hewitt, Alex W; Tam, Patrick P L; White, Melanie D; Nefzger, Christian M; Palpant, Nathan J.

Dev Cell ; 59(6): 705-722.e8, 2024 Mar 25.

Article in English | MEDLINE | ID: mdl-38354738

19.

HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function.

Friedman, Clayton E; Cheetham, Seth W; Negi, Sumedha; Mills, Richard J; Ogawa, Masahito; Redd, Meredith A; Chiu, Han Sheng; Shen, Sophie; Sun, Yuliangzi; Mizikovsky, Dalia; Bouveret, Romaric; Chen, Xiaoli; Voges, Holly K; Paterson, Scott; De Angelis, Jessica E; Andersen, Stacey B; Cao, Yuanzhao; Wu, Yang; Jafrani, Yohaann M A; Yoon, Sohye; Faulkner, Geoffrey J; Smith, Kelly A; Porrello, Enzo; Harvey, Richard P; Hogan, Benjamin M; Nguyen, Quan; Zeng, Jian; Kikuchi, Kazu; Hudson, James E; Palpant, Nathan J.

Dev Cell ; 59(1): 91-107.e6, 2024 Jan 08.

Article in English | MEDLINE | ID: mdl-38091997

20.

Regenerative medicine: Reprogramming the injured heart.