ABSTRACT
The root and rhizoma of Rhodiola fastigita S. H. Fu. is a traditional Tibetan medicine used for promoting blood circulation and relieving cough. In recent years, it was generally used as a tonic. So, its chemical constituents were studied. A new flavonoid and six known compounds were obtained. The known compounds were: 4'-methoxyl herbacetin (I), rhodiolin (II), dihydrokaempferol (III), daucosterol (IV), tyrosyl (V) and salidroside (VI). The structure of the new flavonoid was elucidated as herbacetin-8-O-alpha-D-lyxopyranoside (VII), by means of UV, IR, MS, 1H and 13C-NMR spectral data and chemical methods.
Subject(s)
Flavonoids/isolation & purification , Glycosides/isolation & purification , Phenols , Plants, Medicinal/chemistry , Flavonoids/chemistry , Glucosides/chemistry , Glucosides/isolation & purification , Glycosides/chemistry , Magnoliopsida/chemistry , Molecular StructureABSTRACT
Many species of genus Hedyotis (Rubiaceae) were used as folk medicine for treatment of cold, inflammation, cancer and etc. in China. The alcoholic extract of the whole plant of H. chrysotricha showed good hepatoprotective effects. From the alcoholic extract ten iridoids were isolated and their structures were elucidated as: asperuloside (1), scandoside methyl ester (2), asperulosidic acid (3), deacetyl asperulosidic acid (4), loganin (5), deacetyl asperuloside (6), acetyl scandoside methyl ester (7), 6 beta-hydroxy-genipin (8) and two new compounds named hedyoside (9) and 6'-acetylasperuloside (10), by means of chemical and spectral methods.
Subject(s)
Drugs, Chinese Herbal/chemistry , Glucosides/isolation & purification , Plants, Medicinal/chemistry , Pyrans/isolation & purification , Rubiaceae/chemistry , Glucosides/chemistry , Molecular Structure , Pyrans/chemistryABSTRACT
Five compounds were isolated from the rhizome of Rhodiola kirilowii. Based on spectral studies and chemical analysis the structures were established as tyrosol, daucosterol, lotaustralin, salidroside and sucrose.