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Rev Med Interne ; 30(3): 250-4, 2009 Mar.
Article in French | MEDLINE | ID: mdl-19026472

ABSTRACT

INTRODUCTION: Antiphospholipid antibodies (aPL) can be associated with numerous infectious and particularly Q fever. Data on the pathogenicity of aPL in the course of acute Q fever are scarce. CASE REPORT: We report the case an acute Coxiella burnetii infection associated with clinical and biological manifestations of the aPL syndrome, including a renal infarction. Along with antibiotic treatment, anticoagulation and intravenous immunoglobulins, the clinical outcome was favourable. Antiphospholipid antibodies and Q fever antibody titers had a closely related evolution. CONCLUSION: Arterial thrombosis associated with Q fever and aPL is exceptional. The nosology and potential mechanisms are discussed.


Subject(s)
Antiphospholipid Syndrome/complications , Q Fever/complications , Renal Artery Obstruction/complications , Thrombosis/complications , Acute Disease , Adult , Antibodies, Anticardiolipin , Anticoagulants/administration & dosage , Anticoagulants/therapeutic use , Follow-Up Studies , Humans , Immunoglobulins, Intravenous/therapeutic use , Male , Q Fever/diagnosis , Q Fever/drug therapy , Renal Artery Obstruction/diagnostic imaging , Renal Artery Obstruction/drug therapy , Thrombosis/diagnostic imaging , Time Factors , Tomography, X-Ray Computed , Treatment Outcome
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