Search | Virtual Health Library

1.

Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound.

Spiers, Laura; Gray, Michael; Lyon, Paul; Sivakumar, Shivan; Bekkali, Noor; Scott, Shaun; Collins, Linda; Carlisle, Robert; Wu, Feng; Middleton, Mark; Coussios, Constantin.

BMC Cancer ; 23(1): 896, 2023 Sep 23.

Article in English | MEDLINE | ID: mdl-37741968

2.

Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial.

Gray, Michael D; Lyon, Paul C; Mannaris, Christophoros; Folkes, Lisa K; Stratford, Michael; Campo, Leticia; Chung, Daniel Y F; Scott, Shaun; Anderson, Mark; Goldin, Robert; Carlisle, Robert; Wu, Feng; Middleton, Mark R; Gleeson, Fergus V; Coussios, Constantin C.

Radiology ; 291(1): 232-238, 2019 04.

Article in English | MEDLINE | ID: mdl-30644817

3.

Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial.

Lyon, Paul C; Gray, Michael D; Mannaris, Christophoros; Folkes, Lisa K; Stratford, Michael; Campo, Leticia; Chung, Daniel Y F; Scott, Shaun; Anderson, Mark; Goldin, Robert; Carlisle, Robert; Wu, Feng; Middleton, Mark R; Gleeson, Fergus V; Coussios, Constantin C.

Lancet Oncol ; 19(8): 1027-1039, 2018 08.

Article in English | MEDLINE | ID: mdl-30001990

4.

High-frequency jet ventilation under general anesthesia facilitates CT-guided lung tumor thermal ablation compared with normal respiration under conscious analgesic sedation.

Chung, Daniel Yiu Fai; Tse, Donald Man Lap; Boardman, Philip; Gleeson, Fergus Vincent; Little, Mark William; Scott, Shaun Haig; Anderson, Ewan Mark.

J Vasc Interv Radiol ; 25(9): 1463-9, 2014 Sep.

Article in English | MEDLINE | ID: mdl-24819833

5.

Rad52 inactivation is synthetically lethal with BRCA2 deficiency.

Feng, Zhihui; Scott, Shaun P; Bussen, Wendy; Sharma, Girdhar G; Guo, Gongshe; Pandita, Tej K; Powell, Simon N.

Proc Natl Acad Sci U S A ; 108(2): 686-91, 2011 Jan 11.

Article in English | MEDLINE | ID: mdl-21148102

6.

Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer.

Spring, Kevin; Ahangari, Farida; Scott, Shaun P; Waring, Paul; Purdie, David M; Chen, Philip C; Hourigan, Kevin; Ramsay, Jonathan; McKinnon, Peter J; Swift, Michael; Lavin, Martin F.

Nat Genet ; 32(1): 185-90, 2002 Sep.

Article in English | MEDLINE | ID: mdl-12195425

7.

Use of high frequency jet ventilation as a refinement for imaging macaques with respiratory disease.

Sharpe, Sally A; Scott, Shaun; Taylor, Irene; Skinner, Oliver; Clark, Simon O; Smyth, Donna; McIntyre, Anthony; Gleeson, Fergus V; Dennis, Mike J.

Lab Anim ; 54(4): 386-390, 2020 Aug.

Article in English | MEDLINE | ID: mdl-32216534

8.

Cancer stem cells - from initiation to elimination, how far have we reached? (Review).

Akhtar, Kamal; Bussen, Wendy; Scott, Shaun P.

Int J Oncol ; 34(6): 1491-503, 2009 Jun.

Article in English | MEDLINE | ID: mdl-19424566

9.

Functional consequences of sequence alterations in the ATM gene.

Lavin, Martin F; Scott, Shaun; Gueven, Nuri; Kozlov, Sergei; Peng, Cheng; Chen, Philip.

DNA Repair (Amst) ; 3(8-9): 1197-205, 2004.

Article in English | MEDLINE | ID: mdl-15279808

10.

ATM signaling and genomic stability in response to DNA damage.

Lavin, Martin F; Birrell, Geoff; Chen, Philip; Kozlov, Sergei; Scott, Shaun; Gueven, Nuri.

Mutat Res ; 569(1-2): 123-32, 2005 Jan 06.

Article in English | MEDLINE | ID: mdl-15603757

11.

One-step site-directed mutagenesis of ATM cDNA in large (20kb) plasmid constructs.

Scott, Shaun P; Teh, Alison; Peng, Cheng; Lavin, Martin F.

Hum Mutat ; 20(4): 323, 2002 Oct.

Article in English | MEDLINE | ID: mdl-12325032

12.

Analyzing the regulation and function of ATM.

Lavin, Martin F; Scott, Shaun P; Kozlov, Sergei; Gueven, Nuri.

Methods Mol Biol ; 281: 163-78, 2004.

Article in English | MEDLINE | ID: mdl-15220528

13.

The effects of epoetin alfa on transfusion requirements in head and neck cancer patients: a prospective, randomized, placebo-controlled study.

Scott, Shaun N; Boeve, Thomas J; McCulloch, Timothy M; Fitzpatrick, Kari A; Karnell, Lucy H.

Laryngoscope ; 112(7 Pt 1): 1221-9, 2002 Jul.

Article in English | MEDLINE | ID: mdl-12169903

14.

Approaches to sensitizing glioblastoma to radiotherapy: use of lentiviral vectors.

Chuah, Teong Lip; Walker, David Gregory; Wei, Ming; Scott, Shaun; Lavin, Martin Francis.

Int J Oncol ; 40(6): 1963-9, 2012 Jun.

Article in English | MEDLINE | ID: mdl-22447336

15.

Atm and cellular response to DNA damage.

Lavin, Martin F; Kozlov, Sergei; Gueven, Nuri; Peng, Cheng; Birrell, Geoff; Chen, Phillip; Scott, Shaun.

Adv Exp Med Biol ; 570: 457-76, 2005.

Article in English | MEDLINE | ID: mdl-18727511

16.

Disassembly of MDC1 foci is controlled by ubiquitin-proteasome-dependent degradation.

Shi, Wei; Ma, Zhefu; Willers, Henning; Akhtar, Kamal; Scott, Shaun P; Zhang, Jiuqin; Powell, Simon; Zhang, Junran.

J Biol Chem ; 283(46): 31608-16, 2008 Nov 14.

Article in English | MEDLINE | ID: mdl-18757370

17.

The cellular control of DNA double-strand breaks.

Scott, Shaun P; Pandita, Tej K.

J Cell Biochem ; 99(6): 1463-75, 2006 Dec 15.

Article in English | MEDLINE | ID: mdl-16927314

18.

The effects of fluticasone propionate on nasal epithelial potential difference.

Graham, Scott M; Scott, Shaun N; Launspach, Janice; Zabner, Joseph.

Am J Rhinol ; 16(3): 145-9, 2002.

Article in English | MEDLINE | ID: mdl-12141771

19.

Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer.

Scott, Shaun P; Bendix, Regina; Chen, Philip; Clark, Raymond; Dork, Thilo; Lavin, Martin F.

Proc Natl Acad Sci U S A ; 99(2): 925-30, 2002 Jan 22.

Article in English | MEDLINE | ID: mdl-11805335

20.

Quantitative analysis of the expression of ACAT genes in human tissues by real-time PCR.

Smith, Jeffery L; Rangaraj, Kavitha; Simpson, Robert; Maclean, Donald J; Nathanson, Les K; Stuart, Katherine A; Scott, Shaun P; Ramm, Grant A; de Jersey, John.

J Lipid Res ; 45(4): 686-96, 2004 Apr.

Article in English | MEDLINE | ID: mdl-14729857

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