Search | Virtual Health Library

1.

SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.

Kugel, Sita; Sebastián, Carlos; Fitamant, Julien; Ross, Kenneth N; Saha, Supriya K; Jain, Esha; Gladden, Adrianne; Arora, Kshitij S; Kato, Yasutaka; Rivera, Miguel N; Ramaswamy, Sridhar; Sadreyev, Ruslan I; Goren, Alon; Deshpande, Vikram; Bardeesy, Nabeel; Mostoslavsky, Raul.

Cell ; 165(6): 1401-1415, 2016 Jun 02.

Article in English | MEDLINE | ID: mdl-27180906

2.

Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism.

Masri, Selma; Rigor, Paul; Cervantes, Marlene; Ceglia, Nicholas; Sebastian, Carlos; Xiao, Cuiying; Roqueta-Rivera, Manuel; Deng, Chuxia; Osborne, Timothy F; Mostoslavsky, Raul; Baldi, Pierre; Sassone-Corsi, Paolo.

Cell ; 158(3): 659-72, 2014 Jul 31.

Article in English | MEDLINE | ID: mdl-25083875

3.

The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.

Sebastián, Carlos; Zwaans, Bernadette M M; Silberman, Dafne M; Gymrek, Melissa; Goren, Alon; Zhong, Lei; Ram, Oren; Truelove, Jessica; Guimaraes, Alexander R; Toiber, Debra; Cosentino, Claudia; Greenson, Joel K; MacDonald, Alasdair I; McGlynn, Liane; Maxwell, Fraser; Edwards, Joanne; Giacosa, Sofia; Guccione, Ernesto; Weissleder, Ralph; Bernstein, Bradley E; Regev, Aviv; Shiels, Paul G; Lombard, David B; Mostoslavsky, Raul.

Cell ; 151(6): 1185-99, 2012 Dec 07.

Article in English | MEDLINE | ID: mdl-23217706

4.

SIRT3 in calorie restriction: can you hear me now?

Sebastian, Carlos; Mostoslavsky, Raul.

Cell ; 143(5): 667-8, 2010 Nov 24.

Article in English | MEDLINE | ID: mdl-21111225

5.

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.

Zhong, Lei; D'Urso, Agustina; Toiber, Debra; Sebastian, Carlos; Henry, Ryan E; Vadysirisack, Douangsone D; Guimaraes, Alexander; Marinelli, Brett; Wikstrom, Jakob D; Nir, Tomer; Clish, Clary B; Vaitheesvaran, Bhavapriya; Iliopoulos, Othon; Kurland, Irwin; Dor, Yuval; Weissleder, Ralph; Shirihai, Orian S; Ellisen, Leif W; Espinosa, Joaquin M; Mostoslavsky, Raul.

Cell ; 140(2): 280-93, 2010 Jan 22.

Article in English | MEDLINE | ID: mdl-20141841

6.

The resting calcaneal stance position (RCSP): an old dog, with new tricks.

Martinez-Sebastian, Carlos; Gijon-Nogueron, Gabriel; Ramos-Petersen, Laura; Molina-Garcia, Cristina; Sánchez-Gómez, Rubén; Evans, Angela M.

Eur J Pediatr ; 183(3): 1287-1294, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38103102

7.

Childhood obesity and its impact on the characteristics of gait stance phases: a cross-sectional study.

Molina-García, Cristina; López-Del-Amo-Lorente, Andrés; Ramos-Petersen, Laura; Martínez-Sebastián, Carlos; Jiménez-García, José Daniel; Álvarez-Salvago, Francisco; Velázquez-Díaz, Daniel.

Eur J Pediatr ; 183(1): 123-134, 2024 Jan.

Article in English | MEDLINE | ID: mdl-37843611

8.

Effect of using a kinetic wedge during the hallux dorsiflexion resistance test in asymptomatic individuals.

Gómez-Carrión, Álvaro; Sánchez-Gómez, Rubén; Reguera-Medina, José Manuel; Martínez-Sebastián, Carlos; Márquez-Reina, Salvador; Coheña-Jiménez, Manuel; Moisan, Gabriel.

BMC Musculoskelet Disord ; 25(1): 409, 2024 May 24.

Article in English | MEDLINE | ID: mdl-38783248

9.

Development, validation, and psychometric analysis of Foot and Ankle Flexibility Index (FAFI).

Martínez-Sebastián, Carlos; Gijon-Nogueron, Gabriel; Ramos-Petersen, Laura; Morales-Asencio, José Miguel; Molina-García, Cristina; Evans, Angela M.

J Tissue Viability ; 2024 May 22.

Article in English | MEDLINE | ID: mdl-38862327

10.

Metabolic pathways regulating colorectal cancer initiation and progression.

La Vecchia, Sofia; Sebastián, Carlos.

Semin Cell Dev Biol ; 98: 63-70, 2020 02.

Article in English | MEDLINE | ID: mdl-31129171

11.

Kinematic Effect on the Navicular Bone with the Use of Rearfoot Varus Wedge.

Gómez Carrión, Álvaro; de Los Ángeles Atín Arratibel, Maria; Morales Lozano, Maria Rosario; Martínez Sebastián, Carlos; de la Cruz Torres, Blanca; Sánchez-Gómez, Rubén.

Sensors (Basel) ; 22(3)2022 Jan 21.

Article in English | MEDLINE | ID: mdl-35161560

12.

SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling.

Toiber, Debra; Erdel, Fabian; Bouazoune, Karim; Silberman, Dafne M; Zhong, Lei; Mulligan, Peter; Sebastian, Carlos; Cosentino, Claudia; Martinez-Pastor, Barbara; Giacosa, Sofia; D'Urso, Agustina; Näär, Anders M; Kingston, Robert; Rippe, Karsten; Mostoslavsky, Raul.

Mol Cell ; 51(4): 454-68, 2013 Aug 22.

Article in English | MEDLINE | ID: mdl-23911928

13.

Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming.

Kowalik, Marta Anna; Puliga, Elisabetta; Cabras, Lavinia; Sulas, Pia; Petrelli, Annalisa; Perra, Andrea; Ledda-Columbano, Giovanna Maria; Morandi, Andrea; Merlin, Simone; Orrù, Claudia; Sanchez-Martin, Carlos; Fornari, Francesca; Gramantieri, Laura; Parri, Matteo; Rasola, Andrea; Bellomo, Sara Erika; Sebastian, Carlos; Follenzi, Antonia; Giordano, Silvia; Columbano, Amedeo.

J Hepatol ; 72(6): 1159-1169, 2020 06.

Article in English | MEDLINE | ID: mdl-31954205

14.

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine.

Jiang, Hong; Khan, Saba; Wang, Yi; Charron, Guillaume; He, Bin; Sebastian, Carlos; Du, Jintang; Kim, Ray; Ge, Eva; Mostoslavsky, Raul; Hang, Howard C; Hao, Quan; Lin, Hening.

Nature ; 496(7443): 110-3, 2013 Apr 04.

Article in English | MEDLINE | ID: mdl-23552949

15.

The role of mammalian sirtuins in cancer metabolism.

Sebastián, Carlos; Mostoslavsky, Raul.

Semin Cell Dev Biol ; 43: 33-42, 2015 Jul.

Article in English | MEDLINE | ID: mdl-26238985

16.

The response of secondary genes to lipopolysaccharides in macrophages depends on histone deacetylase and phosphorylation of C/EBPß.

Serrat, Neus; Sebastian, Carlos; Pereira-Lopes, Selma; Valverde-Estrella, Lorena; Lloberas, Jorge; Celada, Antonio.

J Immunol ; 192(1): 418-26, 2014 Jan 01.

Article in English | MEDLINE | ID: mdl-24307736

17.

From sirtuin biology to human diseases: an update.

Sebastián, Carlos; Satterstrom, F Kyle; Haigis, Marcia C; Mostoslavsky, Raul.

J Biol Chem ; 287(51): 42444-52, 2012 Dec 14.

Article in English | MEDLINE | ID: mdl-23086954

18.

Microbiota-derived genotoxin tilimycin generates colonic stem cell mutations.

Pöltl, Lisa; Kitsera, Maksym; Raffl, Sandra; Schild, Stefan; Cosic, Amar; Kienesberger, Sabine; Unterhauser, Katrin; Raber, Georg; Lembacher-Fadum, Christian; Breinbauer, Rolf; Gorkiewicz, Gregor; Sebastian, Carlos; Hoefler, Gerald; Zechner, Ellen L.

Cell Rep ; 42(3): 112199, 2023 03 28.

Article in English | MEDLINE | ID: mdl-36870054

19.

Overweight and Obesity: Its Impact on Foot Type, Flexibility, Foot Strength, Plantar Pressure and Stability in Children from 5 to 10 Years of Age: Descriptive Observational Study.

Molina-García, Cristina; Jiménez-García, José Daniel; Velázquez-Díaz, Daniel; Ramos-Petersen, Laura; López-Del-Amo-Lorente, Andrés; Martínez-Sebastián, Carlos; Álvarez-Salvago, Francisco.

Children (Basel) ; 10(4)2023 Apr 07.

Article in English | MEDLINE | ID: mdl-37189945

20.

Effects of Low-Dye Tape on Arch Height and Its Impact on the Medial Gastrocnemius Electromyographic Activity in Structurally Differentiable Foot Types: A Cross-Sectional Observational Study.

Martínez-Sebastián, Carlos; Ramos-Petersen, Laura; Gámez-Guijarro, María; Alabau-Dasi, Raquel; Banwell, George; Núñez-Fernández, Almudena; Sánchez-Gómez, Rubén; Gómez-Carrión, Álvaro.

Life (Basel) ; 13(12)2023 Dec 08.

Article in English | MEDLINE | ID: mdl-38137910

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