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J Pak Med Assoc ; 70(2): 264-267, 2020 Feb.
Article in English | MEDLINE | ID: mdl-32063618

ABSTRACT

OBJECTIVE: To determine the types of paraproteins in patients with multiple myeloma in a tertiary care setting. METHODS: The cross-sectional study was conducted at the Liaquat National Hospital, Karachi, from November 2015 to May 2016, and comprised patients with multiple myeloma selected using consecutive, non-probability sampling technique. Detailed history was taken and immunofixation assay was conducted to assess the type of paraproteins in the patients. Data was recorded on a proforma and analysed using SPSS 22. RESULTS: Of the 87 patients, 62(71.3%) were males and 25(28.7%) were females. The overall mean age was 57.41±10.53 years. Of the total, 52(71.3%), patients had Immunoglobulin G kappa and 61(70%) had Immunoglobulin A kappa paraprotein. CONCLUSIONS: The most common types of paraprotein was found to be Immunoglobulin G kappa followed by Immunoglobulin A kappa.


Subject(s)
Immunoglobulin A/metabolism , Immunoglobulin G/metabolism , Immunoglobulin kappa-Chains/metabolism , Immunoglobulin lambda-Chains/metabolism , Multiple Myeloma/metabolism , Paraproteins/metabolism , Adult , Age Factors , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Sex Factors
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