Search | Virtual Health Library

1.

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.

Rana, Nitish; Privitera, Giuseppe; Kondolf, Hannah C; Bulek, Katarzyna; Lechuga, Susana; De Salvo, Carlo; Corridoni, Daniele; Antanaviciute, Agne; Maywald, Rebecca L; Hurtado, Alexander M; Zhao, Junjie; Huang, Emina H; Li, Xiaoxia; Chan, E Ricky; Simmons, Alison; Bamias, Giorgos; Abbott, Derek W; Heaney, Jason D; Ivanov, Andrei I; Pizarro, Theresa T.

Cell ; 185(2): 283-298.e17, 2022 01 20.

Article in English | MEDLINE | ID: mdl-35021065

2.

Spatiotemporal analysis of human intestinal development at single-cell resolution.

Fawkner-Corbett, David; Antanaviciute, Agne; Parikh, Kaushal; Jagielowicz, Marta; Gerós, Ana Sousa; Gupta, Tarun; Ashley, Neil; Khamis, Doran; Fowler, Darren; Morrissey, Edward; Cunningham, Chris; Johnson, Paul R V; Koohy, Hashem; Simmons, Alison.

Cell ; 184(3): 810-826.e23, 2021 02 04.

Article in English | MEDLINE | ID: mdl-33406409

3.

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.

Rana, Nitish; Privitera, Giuseppe; Kondolf, Hannah C; Bulek, Katarzyna; Lechuga, Susana; De Salvo, Carlo; Corridoni, Daniele; Antanaviciute, Agne; Maywald, Rebecca L; Hurtado, Alexander M; Zhao, Junjie; Huang, Emina H; Li, Xiaoxia; Chan, E Ricky; Simmons, Alison; Bamias, Giorgos; Abbott, Derek W; Heaney, Jason D; Ivanov, Andrei I; Pizarro, Theresa T.

Cell ; 187(4): 1011-1015, 2024 Feb 15.

Article in English | MEDLINE | ID: mdl-38364781

4.

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.

Kinchen, James; Chen, Hannah H; Parikh, Kaushal; Antanaviciute, Agne; Jagielowicz, Marta; Fawkner-Corbett, David; Ashley, Neil; Cubitt, Laura; Mellado-Gomez, Esther; Attar, Moustafa; Sharma, Eshita; Wills, Quin; Bowden, Rory; Richter, Felix C; Ahern, David; Puri, Kamal D; Henault, Jill; Gervais, Francois; Koohy, Hashem; Simmons, Alison.

Cell ; 175(2): 372-386.e17, 2018 10 04.

Article in English | MEDLINE | ID: mdl-30270042

5.

Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Napolitani, Giorgio; Kurupati, Prathiba; Teng, Karen Wei Weng; Gibani, Malick M; Rei, Margarida; Aulicino, Anna; Preciado-Llanes, Lorena; Wong, Michael Thomas; Becht, Etienne; Howson, Lauren; de Haas, Paola; Salio, Mariolina; Blohmke, Christoph J; Olsen, Lars Rønn; Pinto, David Miguel Susano; Scifo, Laura; Jones, Claire; Dobinson, Hazel; Campbell, Danielle; Juel, Helene B; Thomaides-Brears, Helena; Pickard, Derek; Bumann, Dirk; Baker, Stephen; Dougan, Gordon; Simmons, Alison; Gordon, Melita A; Newell, Evan William; Pollard, Andrew J; Cerundolo, Vincenzo.

Nat Immunol ; 20(4): 514, 2019 Apr.

Article in English | MEDLINE | ID: mdl-30862955

6.

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Napolitani, Giorgio; Kurupati, Prathiba; Teng, Karen Wei Weng; Gibani, Malick M; Rei, Margarida; Aulicino, Anna; Preciado-Llanes, Lorena; Wong, Michael Thomas; Becht, Etienne; Howson, Lauren; de Haas, Paola; Salio, Mariolina; Blohmke, Christoph J; Olsen, Lars Rønn; Pinto, David Miguel Susano; Scifo, Laura; Jones, Claire; Dobinson, Hazel; Campbell, Danielle; Juel, Helene B; Thomaides-Brears, Helena; Pickard, Derek; Bumann, Dirk; Baker, Stephen; Dougan, Gordon; Simmons, Alison; Gordon, Melita A; Newell, Evan William; Pollard, Andrew J; Cerundolo, Vincenzo.

Nat Immunol ; 19(7): 742-754, 2018 07.

Article in English | MEDLINE | ID: mdl-29925993

7.

Common heritage of fibroblasts.

Antanaviciute, Agne; Fawkner-Corbett, David; Simmons, Alison.

Nat Immunol ; 22(8): 944-946, 2021 08.

Article in English | MEDLINE | ID: mdl-34262171

8.

Becalming Type 17 Inflammation in Ulcerative Colitis.

Chen, Hannah H; Simmons, Alison.

Immunity ; 50(4): 1029-1031, 2019 04 16.

Article in English | MEDLINE | ID: mdl-30995495

9.

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia.

Moreira, Lucia M; Takawale, Abhijit; Hulsurkar, Mohit; Menassa, David A; Antanaviciute, Agne; Lahiri, Satadru K; Mehta, Neelam; Evans, Neil; Psarros, Constantinos; Robinson, Paul; Sparrow, Alexander J; Gillis, Marc-Antoine; Ashley, Neil; Naud, Patrice; Barallobre-Barreiro, Javier; Theofilatos, Konstantinos; Lee, Angela; Norris, Mary; Clarke, Michele V; Russell, Patricia K; Casadei, Barbara; Bhattacharya, Shoumo; Zajac, Jeffrey D; Davey, Rachel A; Sirois, Martin; Mead, Adam; Simmons, Alison; Mayr, Manuel; Sayeed, Rana; Krasopoulos, George; Redwood, Charles; Channon, Keith M; Tardif, Jean-Claude; Wehrens, Xander H T; Nattel, Stanley; Reilly, Svetlana.

Nature ; 587(7834): 460-465, 2020 11.

Article in English | MEDLINE | ID: mdl-33149301

10.

Colonic epithelial cell diversity in health and inflammatory bowel disease.

Parikh, Kaushal; Antanaviciute, Agne; Fawkner-Corbett, David; Jagielowicz, Marta; Aulicino, Anna; Lagerholm, Christoffer; Davis, Simon; Kinchen, James; Chen, Hannah H; Alham, Nasullah Khalid; Ashley, Neil; Johnson, Errin; Hublitz, Philip; Bao, Leyuan; Lukomska, Joanna; Andev, Rajinder Singh; Björklund, Elisabet; Kessler, Benedikt M; Fischer, Roman; Goldin, Robert; Koohy, Hashem; Simmons, Alison.

Nature ; 567(7746): 49-55, 2019 03.

Article in English | MEDLINE | ID: mdl-30814735

11.

Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens.

Buckley, Paul R; Lee, Chloe H; Ma, Ruichong; Woodhouse, Isaac; Woo, Jeongmin; Tsvetkov, Vasily O; Shcherbinin, Dmitrii S; Antanaviciute, Agne; Shughay, Mikhail; Rei, Margarida; Simmons, Alison; Koohy, Hashem.

Brief Bioinform ; 23(3)2022 05 13.

Article in English | MEDLINE | ID: mdl-35471658

12.

Severity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Pregnancy in Ontario: A Matched Cohort Analysis.

Murison, Kiera R; Grima, Alicia A; Simmons, Alison E; Tuite, Ashleigh R; Fisman, David N.

Clin Infect Dis ; 76(3): e200-e206, 2023 02 08.

Article in English | MEDLINE | ID: mdl-35792660

13.

Relative Virulence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Among Vaccinated and Unvaccinated Individuals Hospitalized With SARS-CoV-2.

Grima, Alicia A; Murison, Kiera R; Simmons, Alison E; Tuite, Ashleigh R; Fisman, David N.

Clin Infect Dis ; 76(3): e409-e415, 2023 02 08.

Article in English | MEDLINE | ID: mdl-35616115

14.

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease.

Preciado-Llanes, Lorena; Aulicino, Anna; Canals, Rocío; Moynihan, Patrick J; Zhu, Xiaojun; Jambo, Ndaru; Nyirenda, Tonney S; Kadwala, Innocent; Sousa Gerós, Ana; Owen, Siân V; Jambo, Kondwani C; Kumwenda, Benjamin; Veerapen, Natacha; Besra, Gurdyal S; Gordon, Melita A; Hinton, Jay C D; Napolitani, Giorgio; Salio, Mariolina; Simmons, Alison.

Proc Natl Acad Sci U S A ; 117(34): 20717-20728, 2020 08 25.

Article in English | MEDLINE | ID: mdl-32788367

15.

HLA-dependent variation in SARS-CoV-2 CD8 ⁺ T cell cross-reactivity with human coronaviruses.

Buckley, Paul R; Lee, Chloe H; Pereira Pinho, Mariana; Ottakandathil Babu, Rosana; Woo, Jeongmin; Antanaviciute, Agne; Simmons, Alison; Ogg, Graham; Koohy, Hashem.

Immunology ; 166(1): 78-103, 2022 05.

Article in English | MEDLINE | ID: mdl-35143694

16.

Causal and Associational Language in Observational Health Research: A Systematic Evaluation.

Haber, Noah A; Wieten, Sarah E; Rohrer, Julia M; Arah, Onyebuchi A; Tennant, Peter W G; Stuart, Elizabeth A; Murray, Eleanor J; Pilleron, Sophie; Lam, Sze Tung; Riederer, Emily; Howcutt, Sarah Jane; Simmons, Alison E; Leyrat, Clémence; Schoenegger, Philipp; Booman, Anna; Dufour, Mi-Suk Kang; O'Donoghue, Ashley L; Baglini, Rebekah; Do, Stefanie; Takashima, Mari De La Rosa; Evans, Thomas Rhys; Rodriguez-Molina, Daloha; Alsalti, Taym M; Dunleavy, Daniel J; Meyerowitz-Katz, Gideon; Antonietti, Alberto; Calvache, Jose A; Kelson, Mark J; Salvia, Meg G; Parra, Camila Olarte; Khalatbari-Soltani, Saman; McLinden, Taylor; Chatton, Arthur; Seiler, Jessie; Steriu, Andreea; Alshihayb, Talal S; Twardowski, Sarah E; Dabravolskaj, Julia; Au, Eric; Hoopsick, Rachel A; Suresh, Shashank; Judd, Nicholas; Peña, Sebastián; Axfors, Cathrine; Khan, Palwasha; Rivera Aguirre, Ariadne E; Odo, Nnaemeka U; Schmid, Ian; Fox, Matthew P.

Am J Epidemiol ; 191(12): 2084-2097, 2022 11 19.

Article in English | MEDLINE | ID: mdl-35925053

17.

Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration.

Koppens, Martijn A J; Davis, Hayley; Valbuena, Gabriel N; Mulholland, Eoghan J; Nasreddin, Nadia; Colombe, Mathilde; Antanaviciute, Agne; Biswas, Sujata; Friedrich, Matthias; Lee, Lennard; Wang, Lai Mun; Koelzer, Viktor H; East, James E; Simmons, Alison; Winton, Douglas J; Leedham, Simon J.

Gastroenterology ; 161(1): 239-254.e9, 2021 07.

Article in English | MEDLINE | ID: mdl-33819486

18.

Interferon-Gamma-Producing CD8⁺ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor-Colitis.

Sasson, Sarah C; Slevin, Stephanie M; Cheung, Vincent T F; Nassiri, Isar; Olsson-Brown, Anna; Fryer, Eve; Ferreira, Ricardo C; Trzupek, Dominik; Gupta, Tarun; Al-Hillawi, Lulia; Issaias, Mari-Lenna; Easton, Alistair; Campo, Leticia; FitzPatrick, Michael E B; Adams, Joss; Chitnis, Meenali; Protheroe, Andrew; Tuthill, Mark; Coupe, Nicholas; Simmons, Alison; Payne, Miranda; Middleton, Mark R; Travis, Simon P L; Fairfax, Benjamin P; Klenerman, Paul; Brain, Oliver.

Gastroenterology ; 161(4): 1229-1244.e9, 2021 10.

Article in English | MEDLINE | ID: mdl-34147519

19.

The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.

Brain, Oliver; Owens, Benjamin M J; Pichulik, Tica; Allan, Philip; Khatamzas, Elham; Leslie, Alasdair; Steevels, Tessa; Sharma, Sameer; Mayer, Alice; Catuneanu, Ana Maria; Morton, Victoria; Sun, Mei-Yi; Jewell, Derek; Coccia, Margherita; Harrison, Oliver; Maloy, Kevin; Schönefeldt, Susann; Bornschein, Simon; Liston, Adrian; Simmons, Alison.

Immunity ; 39(3): 521-36, 2013 Sep 19.

Article in English | MEDLINE | ID: mdl-24054330

20.

Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.

Khatamzas, Elham; Hipp, Madeleine Maria; Gaughan, Daniel; Pichulik, Tica; Leslie, Alasdair; Fernandes, Ricardo A; Muraro, Daniele; Booth, Sarah; Zausmer, Kieran; Sun, Mei-Yi; Kessler, Benedikt; Rowland-Jones, Sarah; Cerundolo, Vincenzo; Simmons, Alison.

EMBO J ; 36(20): 2998-3011, 2017 10 16.

Article in English | MEDLINE | ID: mdl-28923824

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GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.

Spatiotemporal analysis of human intestinal development at single-cell resolution.

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.

Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Common heritage of fibroblasts.

Becalming Type 17 Inflammation in Ulcerative Colitis.

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia.

Colonic epithelial cell diversity in health and inflammatory bowel disease.

Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens.

Severity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Pregnancy in Ontario: A Matched Cohort Analysis.

Relative Virulence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Among Vaccinated and Unvaccinated Individuals Hospitalized With SARS-CoV-2.

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease.

HLA-dependent variation in SARS-CoV-2 CD8 ⁺ T cell cross-reactivity with human coronaviruses.

Causal and Associational Language in Observational Health Research: A Systematic Evaluation.

Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration.

Interferon-Gamma-Producing CD8⁺ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor-Colitis.

The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.

Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.