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1.
Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity.
J Struct Biol
; 211(1): 107512, 2020 07 01.
Article
in English
| MEDLINE | ID: mdl-32325220
2.
Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinaseâ A as a Structure Surrogate.
Chembiochem
; 19(6): 613-621, 2018 03 16.
Article
in English
| MEDLINE | ID: mdl-29314498
3.
Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.
Biochim Biophys Acta
; 1860(11 Pt A): 2537-2552, 2016 11.
Article
in English
| MEDLINE | ID: mdl-27474998
4.
Cryo-EM structure of human PAPP-A2 and mechanism of substrate recognition.
Commun Chem
; 6(1): 234, 2023 Oct 28.
Article
in English
| MEDLINE | ID: mdl-37898658
5.
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition.
Nat Commun
; 13(1): 5500, 2022 09 20.
Article
in English
| MEDLINE | ID: mdl-36127359
6.
Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site.
Sci Rep
; 12(1): 14561, 2022 08 26.
Article
in English
| MEDLINE | ID: mdl-36028520
7.
Hepatitis C NS5B polymerase inhibitors: functional equivalents for the benzothiadiazine moiety.
Bioorg Med Chem Lett
; 21(6): 1876-9, 2011 Mar 15.
Article
in English
| MEDLINE | ID: mdl-21316235
8.
Complex of human Melanotransferrin and SC57.32 Fab fragment reveals novel interdomain arrangement with ferric N-lobe and open C-lobe.
Sci Rep
; 11(1): 566, 2021 01 12.
Article
in English
| MEDLINE | ID: mdl-33436675
9.
Sugar phosphate activation of the stress sensor eIF2B.
Nat Commun
; 12(1): 3440, 2021 06 08.
Article
in English
| MEDLINE | ID: mdl-34103529
10.
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design.
J Med Chem
; 64(1): 417-429, 2021 01 14.
Article
in English
| MEDLINE | ID: mdl-33378180
11.
Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket.
Bioorg Med Chem Lett
; 20(2): 612-7, 2010 Jan 15.
Article
in English
| MEDLINE | ID: mdl-20004576
12.
Accelerating pharmaceutical structure-guided drug design: a successful model.
Drug Discov Today
; 24(2): 377-381, 2019 02.
Article
in English
| MEDLINE | ID: mdl-30448353
13.
Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.
J Med Chem
; 62(8): 4120-4130, 2019 04 25.
Article
in English
| MEDLINE | ID: mdl-30933499
14.
Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives.
Bioorg Med Chem Lett
; 18(14): 3887-90, 2008 Jul 15.
Article
in English
| MEDLINE | ID: mdl-18599294
15.
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.
J Med Chem
; 61(24): 11074-11100, 2018 12 27.
Article
in English
| MEDLINE | ID: mdl-30384606
16.
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotension.
J Med Chem
; 50(13): 2990-3003, 2007 Jun 28.
Article
in English
| MEDLINE | ID: mdl-17523610
17.
Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based orally active multitargeted receptor tyrosine kinase inhibitor.
J Med Chem
; 50(7): 1584-97, 2007 Apr 05.
Article
in English
| MEDLINE | ID: mdl-17343372
18.
Author Correction: Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition.
Nat Commun
; 13(1): 5694, 2022 Sep 28.
Article
in English
| MEDLINE | ID: mdl-36171222
19.
Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo.
Mol Cancer Ther
; 4(6): 977-86, 2005 Jun.
Article
in English
| MEDLINE | ID: mdl-15956255
20.
Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure.
Protein Sci
; 14(12): 3039-47, 2005 Dec.
Article
in English
| MEDLINE | ID: mdl-16322581