Search | Virtual Health Library

1.

PD-1 cooperates with AIRE-mediated tolerance to prevent lethal autoimmune disease.

Policheni, Antonia N; Teh, Charis E; Robbins, Alissa; Tuzlak, Selma; Strasser, Andreas; Gray, Daniel H D.

Proc Natl Acad Sci U S A ; 119(15): e2120149119, 2022 04 12.

Article in English | MEDLINE | ID: mdl-35394861

2.

Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy.

Thijssen, Rachel; Tian, Luyi; Anderson, Mary Ann; Flensburg, Christoffer; Jarratt, Andrew; Garnham, Alexandra L; Jabbari, Jafar S; Peng, Hongke; Lew, Thomas E; Teh, Charis E; Gouil, Quentin; Georgiou, Angela; Tan, Tania; Djajawi, Tirta M; Tam, Constantine S; Seymour, John F; Blombery, Piers; Gray, Daniel H D; Majewski, Ian J; Ritchie, Matthew E; Roberts, Andrew W; Huang, David C S.

Blood ; 140(20): 2127-2141, 2022 11 17.

Article in English | MEDLINE | ID: mdl-35709339

3.

ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes.

Yabas, Mehmet; Teh, Charis E; Frankenreiter, Sandra; Lal, Dennis; Roots, Carla M; Whittle, Belinda; Andrews, Daniel T; Zhang, Yafei; Teoh, Narci C; Sprent, Jonathan; Tze, Lina E; Kucharska, Edyta M; Kofler, Jennifer; Farell, Geoffrey C; Bröer, Stefan; Goodnow, Christopher C; Enders, Anselm.

Nat Immunol ; 12(5): 441-9, 2011 May.

Article in English | MEDLINE | ID: mdl-21423173

4.

Characterization of Blimp-1 function in effector regulatory T cells.

Cretney, Erika; Leung, Patrick Sk; Trezise, Stephanie; Newman, Dane M; Rankin, Lucille C; Teh, Charis E; Putoczki, Tracy L; Gray, Daniel Hd; Belz, Gabrielle T; Mielke, Lisa A; Dias, Sheila; Nutt, Stephen L.

J Autoimmun ; 91: 73-82, 2018 07.

Article in English | MEDLINE | ID: mdl-29724515

5.

Can you rely on Treg cells on the rebound?

Teh, Charis E; Gray, Daniel H D.

Eur J Immunol ; 44(12): 3504-7, 2014 Dec.

Article in English | MEDLINE | ID: mdl-25410151

6.

Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers.

Joyce, Rachel; Pascual, Rosa; Heitink, Luuk; Capaldo, Bianca D; Vaillant, François; Christie, Michael; Tsai, Minhsuang; Surgenor, Elliot; Anttila, Casey J A; Rajasekhar, Pradeep; Jackling, Felicity C; Trussart, Marie; Milevskiy, Michael J G; Song, Xiaoyu; Li, Mengbo; Teh, Charis E; Gray, Daniel H D; Smyth, Gordon K; Chen, Yunshun; Lindeman, Geoffrey J; Visvader, Jane E.

Nat Cell Biol ; 26(1): 138-152, 2024 Jan.

Article in English | MEDLINE | ID: mdl-38216737

7.

T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency.

Teh, Charis E; Daley, Stephen R; Enders, Anselm; Goodnow, Christopher C.

Proc Natl Acad Sci U S A ; 107(33): 14709-14, 2010 Aug 17.

Article in English | MEDLINE | ID: mdl-20668237

8.

Venetoclax treatment in patients with cancer has limited impact on circulating T and NK cells.

Teh, Charis E; Peng, Hongke; Luo, Meng-Xiao; Tan, Tania; Trussart, Marie; Howson, Lauren J; Chua, Chong Chyn; Muttiah, Christine; Brown, Fiona; Ritchie, Matthew E; Wei, Andrew H; Roberts, Andrew W; Bryant, Vanessa L; Anderson, Mary Ann; Lindeman, Geoffrey J; Huang, David C S; Thijssen, Rachel; Gray, Daniel H D.

Blood Adv ; 7(12): 2733-2745, 2023 Jun 27.

Article in English | MEDLINE | ID: mdl-36521105

9.

Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer.

Weeden, Clare E; Gayevskiy, Velimir; Marceaux, Claire; Batey, Daniel; Tan, Tania; Yokote, Kenta; Ribera, Nina Tubau; Clatch, Allison; Christo, Susan; Teh, Charis E; Mitchell, Andrew J; Trussart, Marie; Rankin, Lucille; Obers, Andreas; McDonald, Jackson A; Sutherland, Kate D; Sharma, Varun J; Starkey, Graham; D'Costa, Rohit; Antippa, Phillip; Leong, Tracy; Steinfort, Daniel; Irving, Louis; Swanton, Charles; Gordon, Claire L; Mackay, Laura K; Speed, Terence P; Gray, Daniel H D; Asselin-Labat, Marie-Liesse.

Cancer Cell ; 41(5): 837-852.e6, 2023 05 08.

Article in English | MEDLINE | ID: mdl-37086716

10.

Single-Cell Profiling of the Intrinsic Apoptotic Pathway by Mass Cytometry (CyTOF).

Tan, Tania; Gray, Daniel H D; Teh, Charis E.

Methods Mol Biol ; 2543: 83-97, 2022.

Article in English | MEDLINE | ID: mdl-36087261

11.

The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance.

Heinlein, Melanie; Gandolfo, Luke C; Zhao, Kelin; Teh, Charis E; Nguyen, Nghi; Baell, Jonathan B; Goldfarb, Yael; Abramson, Jakub; Wichmann, Johannes; Voss, Anne K; Strasser, Andreas; Smyth, Gordon K; Thomas, Tim; Gray, Daniel H D.

Sci Immunol ; 7(67): eabb6032, 2022 01 21.

Article in English | MEDLINE | ID: mdl-35061506

12.

Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damage.

Teh, Charis E; Preston, Simon P; Robbins, Alissa K; Stutz, Michael D; Cooney, James; Clark, Michelle P; Policheni, Antonia N; Allison, Cody C; Mackiewicz, Liana; Arandjelovic, Philip; Ebert, Gregor; Doerflinger, Marcel; Tan, Tania; Rankin, Lucille C; Teh, Peggy P; Belz, Gabrielle T; Kallies, Axel; Strasser, Andreas; Pellegrini, Marc; Gray, Daniel H D.

Sci Immunol ; 7(69): eabn8041, 2022 03 25.

Article in English | MEDLINE | ID: mdl-35333545

13.

Removing unwanted variation with CytofRUV to integrate multiple CyTOF datasets.

Trussart, Marie; Teh, Charis E; Tan, Tania; Leong, Lawrence; Gray, Daniel Hd; Speed, Terence P.

Elife ; 92020 09 07.

Article in English | MEDLINE | ID: mdl-32894218

14.

MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3⁺ regulatory T cells.

Teh, Charis E; Robbins, Alissa K; Henstridge, Darren C; Dewson, Grant; Diepstraten, Sarah T; Kelly, Gemma; Febbraio, Mark A; Gabriel, Sarah S; O'Reilly, Lorraine A; Strasser, Andreas; Gray, Daniel H D.

Cell Death Differ ; 27(12): 3374-3385, 2020 12.

Article in English | MEDLINE | ID: mdl-32612106

15.

Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma.

Dengler, Michael A; Teh, Charis E; Thijssen, Rachel; Gangoda, Lahiru; Lan, Ping; Herold, Marco J; Gray, Daniel H; Kelly, Gemma L; Roberts, Andrew W; Adams, Jerry M.

Oncogene ; 39(9): 2009-2023, 2020 02.

Article in English | MEDLINE | ID: mdl-31772331

16.

Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells.

Teh, Charis E; Gong, Jia-Nan; Segal, David; Tan, Tania; Vandenberg, Cassandra J; Fedele, Pasquale L; Low, Michael S Y; Grigoriadis, George; Harrison, Simon J; Strasser, Andreas; Roberts, Andrew W; Huang, David C S; Nolan, Garry P; Gray, Daniel H D; Ko, Melissa E.

Cell Death Differ ; 27(7): 2217-2233, 2020 07.

Article in English | MEDLINE | ID: mdl-31988495

17.

Deletion of self-reactive CCR7- thymocytes in the absence of MHC expression on thymic epithelial cells.

Wirasinha, Rushika C; Chan, Anna; Yap, Jin Yan; Hu, Daniel Y; Teh, Charis E; Gray, Daniel H D; Goodnow, Christopher C; Daley, Stephen R.

Cell Death Differ ; 26(12): 2727-2739, 2019 12.

Article in English | MEDLINE | ID: mdl-31019259

18.

Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia.

Blombery, Piers; Anderson, Mary Ann; Gong, Jia-Nan; Thijssen, Rachel; Birkinshaw, Richard W; Thompson, Ella R; Teh, Charis E; Nguyen, Tamia; Xu, Zhen; Flensburg, Christoffer; Lew, Thomas E; Majewski, Ian J; Gray, Daniel H D; Westerman, David A; Tam, Constantine S; Seymour, John F; Czabotar, Peter E; Huang, David C S; Roberts, Andrew W.

Cancer Discov ; 9(3): 342-353, 2019 03.

Article in English | MEDLINE | ID: mdl-30514704

19.

Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma.

Agarwal, Rishu; Chan, Yih-Chih; Tam, Constantine S; Hunter, Tane; Vassiliadis, Dane; Teh, Charis E; Thijssen, Rachel; Yeh, Paul; Wong, Stephen Q; Ftouni, Sarah; Lam, Enid Y N; Anderson, Mary Ann; Pott, Christiane; Gilan, Omer; Bell, Charles C; Knezevic, Kathy; Blombery, Piers; Rayeroux, Kathleen; Zordan, Adrian; Li, Jason; Huang, David C S; Wall, Meaghan; Seymour, John F; Gray, Daniel H D; Roberts, Andrew W; Dawson, Mark A; Dawson, Sarah-Jane.

Nat Med ; 25(1): 119-129, 2019 01.

Article in English | MEDLINE | ID: mdl-30455436

20.

A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2-Positive Metastatic Breast Cancer.

Lok, Sheau W; Whittle, James R; Vaillant, François; Teh, Charis E; Lo, Louisa L; Policheni, Antonia N; Bergin, Alice R T; Desai, Jayesh; Ftouni, Sarah; Gandolfo, Luke C; Liew, Danny; Liu, He K; Mann, G Bruce; Moodie, Kate; Murugasu, Anand; Pal, Bhupinder; Roberts, Andrew W; Rosenthal, Mark A; Shackleton, Kylie; Silva, Maria João; Siow, Zhen R; Smyth, Gordon K; Taylor, Leanne; Travers, Avraham; Yeo, Belinda; Yeung, Miriam M; Bujak, Andjelija Zivanovic; Dawson, Sarah-Jane; Gray, Daniel H D; Visvader, Jane E; Lindeman, Geoffrey J.

Cancer Discov ; 9(3): 354-369, 2019 03.

Article in English | MEDLINE | ID: mdl-30518523

Virtual Health Library

United States - Mexico Border

Your selection (0)

Export format:

Export: