ABSTRACT
Renal artery embolism is an infrequent entity that occurs in patients with underlying cardiac diseases. Diagnosis is usually difficult unless the index of suspicion is high. Local thrombolysis with low-dose fibrinolytic agents is an useful therapeutic intervention. We present 2 cases of renal artery embolism treated with intra-arterial urokinase and review clinical features and therapeutic options.
Subject(s)
Embolism/drug therapy , Fibrinolytic Agents/therapeutic use , Renal Artery , Thrombolytic Therapy , Urokinase-Type Plasminogen Activator/therapeutic use , Embolism/diagnostic imaging , Female , Humans , Male , Middle Aged , Radiography , Renal Artery/diagnostic imagingABSTRACT
Pulmonary haemorrhage is a severe complication of small-vessel vasculitis associated with antineutrophil cytoplasm antibodies (ANCA). The main pathologic finding is a pauci-immune capillaritis, although occasionally this lesion is not present. The differential diagnosis includes different diseases and therefore ANCA measurement is important. Two cases of pulmonary haemorrhage associated with ANCA in patients with a clinical picture suggesting small-vessel vasculitis is here reported and a review of the literature is made.