ABSTRACT
Infection with Acanthamoeba is difficult to diagnose and treat. We present the first case of disseminated Acanthamoeba infection in an HIV-infected infant. The infant survived 2 years with treatment with several agents having anti-Acanthamoeba activity in vitro.
Subject(s)
AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , Acanthamoeba/isolation & purification , Amebiasis/diagnosis , Amebiasis/drug therapy , Amebicides/administration & dosage , Anti-Bacterial Agents , Drug Therapy, Combination/administration & dosage , Animals , Biopsy, Needle , Disease Progression , Fatal Outcome , Humans , Immunohistochemistry , Infant , Male , Severity of Illness IndexABSTRACT
Lipoblastoma, a rare benign tumor of adipose tissue, typically occurs in the superficial or deep layers of soft tissue on the trunk or extremities. Other sites of occurrence include the head, neck, and retroperitoneum. Lipoblastoma of the chest wall and parietal pleural have been reported, but occurrence within the lung has not been previously described. We report a case of pulmonary lipoblastoma in a young child presenting with complete opacification of the left hemithorax and mediastinal shift on chest radiograph. A lobectomy was performed, and the diagnosis was made by histological examination.