Search details
1.
Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.
Cell
; 173(1): 260-274.e25, 2018 03 22.
Article
in English
| MEDLINE | ID: mdl-29551266
2.
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition.
Mol Syst Biol
; 20(4): 458-474, 2024 Apr.
Article
in English
| MEDLINE | ID: mdl-38454145
3.
Meltome atlas-thermal proteome stability across the tree of life.
Nat Methods
; 17(5): 495-503, 2020 05.
Article
in English
| MEDLINE | ID: mdl-32284610
4.
Improved Proteomics-Based Drug Mechanism-of-Action Studies Using 16-Plex Isobaric Mass Tags.
J Proteome Res
; 20(3): 1792-1801, 2021 03 05.
Article
in English
| MEDLINE | ID: mdl-33621079
5.
Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition.
J Am Chem Soc
; 140(3): 932-939, 2018 01 24.
Article
in English
| MEDLINE | ID: mdl-29232121
6.
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.
Nat Methods
; 12(12): 1129-31, 2015 Dec.
Article
in English
| MEDLINE | ID: mdl-26524241
7.
Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.
Nat Chem Biol
; 12(11): 908-910, 2016 Nov.
Article
in English
| MEDLINE | ID: mdl-27669419
8.
Ion coalescence of neutron encoded TMT 10-plex reporter ions.
Anal Chem
; 86(7): 3594-601, 2014 Apr 01.
Article
in English
| MEDLINE | ID: mdl-24579773
9.
A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation.
Nat Chem Biol
; 8(6): 576-82, 2012 Apr 29.
Article
in English
| MEDLINE | ID: mdl-22544264
10.
Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells.
Cancer Discov
; 2024 Apr 09.
Article
in English
| MEDLINE | ID: mdl-38587317
11.
High-resolution enabled TMT 8-plexing.
Anal Chem
; 84(16): 7188-94, 2012 Aug 21.
Article
in English
| MEDLINE | ID: mdl-22881393
12.
Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.
Bioorg Med Chem Lett
; 22(14): 4613-8, 2012 Jul 15.
Article
in English
| MEDLINE | ID: mdl-22726925
13.
Affinity Enrichment Chemoproteomics for Target Deconvolution and Selectivity Profiling.
Methods Mol Biol
; 2228: 237-252, 2021.
Article
in English
| MEDLINE | ID: mdl-33950495
14.
BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.
Sci Adv
; 7(22)2021 05.
Article
in English
| MEDLINE | ID: mdl-34039605
15.
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia.
Nat Cancer
; 2(10): 1002-1017, 2021 10.
Article
in English
| MEDLINE | ID: mdl-34790902
16.
Computational prediction of proteotypic peptides for quantitative proteomics.
Nat Biotechnol
; 25(1): 125-31, 2007 Jan.
Article
in English
| MEDLINE | ID: mdl-17195840
17.
GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins.
J Med Chem
; 63(17): 9045-9069, 2020 09 10.
Article
in English
| MEDLINE | ID: mdl-32691589
18.
Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.
J Med Chem
; 63(11): 5816-5840, 2020 06 11.
Article
in English
| MEDLINE | ID: mdl-32410449
19.
Identifying drug targets in tissues and whole blood with thermal-shift profiling.
Nat Biotechnol
; 38(3): 303-308, 2020 03.
Article
in English
| MEDLINE | ID: mdl-31959954
20.
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Science
; 368(6489): 387-394, 2020 04 24.
Article
in English
| MEDLINE | ID: mdl-32193360