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1.
Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.
Bioorg Med Chem
; 100: 117618, 2024 Feb 15.
Article
in English
| MEDLINE | ID: mdl-38309201
2.
Parasite manipulation of host phenotypes inferred from transcriptional analyses in a trematode-amphipod system.
Mol Ecol
; 32(18): 5028-5041, 2023 09.
Article
in English
| MEDLINE | ID: mdl-37540037
3.
An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model.
Bioorg Med Chem Lett
; 28(10): 1958-1963, 2018 06 01.
Article
in English
| MEDLINE | ID: mdl-29653895
4.
Plant Translation Initiation Complex eIFiso4F Directs Pokeweed Antiviral Protein to Selectively Depurinate Uncapped Tobacco Etch Virus RNA.
Biochemistry
; 56(45): 5980-5990, 2017 11 14.
Article
in English
| MEDLINE | ID: mdl-29064680
5.
A human fatty acid synthase inhibitor binds ß-ketoacyl reductase in the keto-substrate site.
Nat Chem Biol
; 10(9): 774-9, 2014 Sep.
Article
in English
| MEDLINE | ID: mdl-25086508
6.
Prevalence and associated risk factors of burnout among US doctors of chiropractic.
J Manipulative Physiol Ther
; 37(3): 180-9, 2014.
Article
in English
| MEDLINE | ID: mdl-24387887
7.
Prevalence of burnout among doctors of chiropractic in the northeastern United States.
J Manipulative Physiol Ther
; 36(6): 376-84, 2013.
Article
in English
| MEDLINE | ID: mdl-23896167
8.
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor.
Proc Natl Acad Sci U S A
; 106(43): 18114-9, 2009 Oct 27.
Article
in English
| MEDLINE | ID: mdl-19822747
9.
Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J Mol Biol
; 434(2): 167395, 2022 01 30.
Article
in English
| MEDLINE | ID: mdl-34896364
10.
Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene.
Bioorg Med Chem Lett
; 21(20): 6154-60, 2011 Oct 15.
Article
in English
| MEDLINE | ID: mdl-21890356
11.
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.
Bioorg Med Chem Lett
; 21(4): 1206-13, 2011 Feb 15.
Article
in English
| MEDLINE | ID: mdl-21256005
12.
Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.
ACS Med Chem Lett
; 12(9): 1396-1404, 2021 Sep 09.
Article
in English
| MEDLINE | ID: mdl-34531948
13.
Improving the developability profile of pyrrolidine progesterone receptor partial agonists.
Bioorg Med Chem Lett
; 20(1): 371-4, 2010 Jan 01.
Article
in English
| MEDLINE | ID: mdl-19926282
14.
The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist.
Acta Crystallogr D Biol Crystallogr
; 65(Pt 5): 449-61, 2009 May.
Article
in English
| MEDLINE | ID: mdl-19390150
15.
Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064.
Bioorg Med Chem Lett
; 19(11): 2969-73, 2009 Jun 01.
Article
in English
| MEDLINE | ID: mdl-19410460
16.
2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.
Bioorg Med Chem Lett
; 19(17): 4916-9, 2009 Sep 01.
Article
in English
| MEDLINE | ID: mdl-19664922
17.
Rational design of orally-active, pyrrolidine-based progesterone receptor partial agonists.
Bioorg Med Chem Lett
; 19(16): 4777-80, 2009 Aug 15.
Article
in English
| MEDLINE | ID: mdl-19595590
18.
Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists.
Bioorg Med Chem Lett
; 19(16): 4664-8, 2009 Aug 15.
Article
in English
| MEDLINE | ID: mdl-19616429
19.
FXR agonist activity of conformationally constrained analogs of GW 4064.
Bioorg Med Chem Lett
; 19(16): 4733-9, 2009 Aug 15.
Article
in English
| MEDLINE | ID: mdl-19586769
20.
Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor.
J Med Chem
; 62(7): 3254-3267, 2019 04 11.
Article
in English
| MEDLINE | ID: mdl-30763090