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1.
The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development.
Pharmacol Res
; 195: 106853, 2023 09.
Article
in English
| MEDLINE | ID: mdl-37473876
2.
Organic anion transporters 1 and 3 influence cellular energy metabolism in renal proximal tubule cells.
Biol Chem
; 400(10): 1347-1358, 2019 09 25.
Article
in English
| MEDLINE | ID: mdl-30653465
3.
Recellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity Screening.
Drug Metab Dispos
; 46(9): 1338-1350, 2018 09.
Article
in English
| MEDLINE | ID: mdl-29980578
4.
Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity.
Drug Metab Dispos
; 46(5): 592-599, 2018 05.
Article
in English
| MEDLINE | ID: mdl-29514829
5.
A novel multi-parametric high content screening assay in ciPTEC-OAT1 to predict drug-induced nephrotoxicity during drug discovery.
Arch Toxicol
; 92(10): 3175-3190, 2018 10.
Article
in English
| MEDLINE | ID: mdl-30155723
6.
Cetuximab Prevents Methotrexate-Induced Cytotoxicity in Vitro through Epidermal Growth Factor Dependent Regulation of Renal Drug Transporters.
Mol Pharm
; 14(6): 2147-2157, 2017 06 05.
Article
in English
| MEDLINE | ID: mdl-28493713
7.
Fluorescence-Based Transport Assays Revisited in a Human Renal Proximal Tubule Cell Line.
Mol Pharm
; 13(3): 933-44, 2016 Mar 07.
Article
in English
| MEDLINE | ID: mdl-26871298
8.
Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients.
Proc Natl Acad Sci U S A
; 110(17): 7014-9, 2013 Apr 23.
Article
in English
| MEDLINE | ID: mdl-23572577
9.
Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.
Pflugers Arch
; 466(8): 1591-604, 2014 Aug.
Article
in English
| MEDLINE | ID: mdl-24193408
10.
Epithelial-to-mesenchymal transition in fibrosis: collagen type I expression is highly upregulated after EMT, but does not contribute to collagen deposition.
Exp Cell Res
; 319(19): 3000-9, 2013 Nov 15.
Article
in English
| MEDLINE | ID: mdl-23906925
11.
Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter.
Pflugers Arch
; 465(12): 1701-14, 2013 Dec.
Article
in English
| MEDLINE | ID: mdl-23812163
12.
Cysteamine restores glutathione redox status in cultured cystinotic proximal tubular epithelial cells.
Biochim Biophys Acta
; 1812(6): 643-51, 2011 Jun.
Article
in English
| MEDLINE | ID: mdl-21371554
13.
Cystinosis: practical tools for diagnosis and treatment.
Pediatr Nephrol
; 26(2): 205-15, 2011 Feb.
Article
in English
| MEDLINE | ID: mdl-20734088
14.
Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies.
J Pharm Sci
; 110(4): 1601-1614, 2021 04.
Article
in English
| MEDLINE | ID: mdl-33545187
15.
The pathogenesis of cystinosis: mechanisms beyond cystine accumulation.
Am J Physiol Renal Physiol
; 299(5): F905-16, 2010 Nov.
Article
in English
| MEDLINE | ID: mdl-20826575
16.
Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters.
Cell Tissue Res
; 339(2): 449-57, 2010 Feb.
Article
in English
| MEDLINE | ID: mdl-19902259
17.
Analysis of CTNS gene transcripts in nephropathic cystinosis.
Pediatr Nephrol
; 25(7): 1263-7, 2010 Jul.
Article
in English
| MEDLINE | ID: mdl-20352457
18.
Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia.
Biochim Biophys Acta Gen Subj
; 1864(1): 129433, 2020 01.
Article
in English
| MEDLINE | ID: mdl-31520681
19.
FXYD2 and Na,K-ATPase expression in isolated human proximal tubular cells: disturbed upregulation on renal hypomagnesemia?
J Membr Biol
; 231(2-3): 117-24, 2009 Oct.
Article
in English
| MEDLINE | ID: mdl-19865785
20.
Therapy with 2'-O-Me Phosphorothioate Antisense Oligonucleotides Causes Reversible Proteinuria by Inhibiting Renal Protein Reabsorption.
Mol Ther Nucleic Acids
; 18: 298-307, 2019 Dec 06.
Article
in English
| MEDLINE | ID: mdl-31610379