Search | Virtual Health Library

1.

Complement in breast milk modifies offspring gut microbiota to promote infant health.

Xu, Dongqing; Zhou, Siyu; Liu, Yue; Scott, Alan L; Yang, Jian; Wan, Fengyi.

Cell ; 187(3): 750-763.e20, 2024 Feb 01.

Article in English | MEDLINE | ID: mdl-38242132

2.

Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model.

Wray, Naomi R; Wijmenga, Cisca; Sullivan, Patrick F; Yang, Jian; Visscher, Peter M.

Cell ; 173(7): 1573-1580, 2018 06 14.

Article in English | MEDLINE | ID: mdl-29906445

3.

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.

Pairo-Castineira, Erola; Rawlik, Konrad; Bretherick, Andrew D; Qi, Ting; Wu, Yang; Nassiri, Isar; McConkey, Glenn A; Zechner, Marie; Klaric, Lucija; Griffiths, Fiona; Oosthuyzen, Wilna; Kousathanas, Athanasios; Richmond, Anne; Millar, Jonathan; Russell, Clark D; Malinauskas, Tomas; Thwaites, Ryan; Morrice, Kirstie; Keating, Sean; Maslove, David; Nichol, Alistair; Semple, Malcolm G; Knight, Julian; Shankar-Hari, Manu; Summers, Charlotte; Hinds, Charles; Horby, Peter; Ling, Lowell; McAuley, Danny; Montgomery, Hugh; Openshaw, Peter J M; Begg, Colin; Walsh, Timothy; Tenesa, Albert; Flores, Carlos; Riancho, José A; Rojas-Martinez, Augusto; Lapunzina, Pablo; Yang, Jian; Ponting, Chris P; Wilson, James F; Vitart, Veronique; Abedalthagafi, Malak; Luchessi, Andre D; Parra, Esteban J; Cruz, Raquel; Carracedo, Angel; Fawkes, Angie; Murphy, Lee; Rowan, Kathy.

Nature ; 617(7962): 764-768, 2023 05.

Article in English | MEDLINE | ID: mdl-37198478

4.

LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice.

Wang, Xin; Li, Zhi-Tong; Yan, Yue; Lin, Penghui; Tang, Wei; Hasler, Daniele; Meduri, Rajyalakshmi; Li, Ye; Hua, Min-Min; Qi, Hui-Tao; Lin, Di-Hang; Shi, Hui-Juan; Hui, Jingyi; Li, Jinsong; Li, Dangsheng; Yang, Jian-Hua; Lin, Jinzhong; Meister, Gunter; Fischer, Utz; Liu, Mo-Fang.

Mol Cell ; 77(5): 999-1013.e6, 2020 03 05.

Article in English | MEDLINE | ID: mdl-32017896

5.

From genetic associations to genes: methods, applications, and challenges.

Qi, Ting; Song, Liyang; Guo, Yazhou; Chen, Chang; Yang, Jian.

Trends Genet ; 2024 May 10.

Article in English | MEDLINE | ID: mdl-38734482

6.

Genetic mechanisms of critical illness in COVID-19.

Pairo-Castineira, Erola; Clohisey, Sara; Klaric, Lucija; Bretherick, Andrew D; Rawlik, Konrad; Pasko, Dorota; Walker, Susan; Parkinson, Nick; Fourman, Max Head; Russell, Clark D; Furniss, James; Richmond, Anne; Gountouna, Elvina; Wrobel, Nicola; Harrison, David; Wang, Bo; Wu, Yang; Meynert, Alison; Griffiths, Fiona; Oosthuyzen, Wilna; Kousathanas, Athanasios; Moutsianas, Loukas; Yang, Zhijian; Zhai, Ranran; Zheng, Chenqing; Grimes, Graeme; Beale, Rupert; Millar, Jonathan; Shih, Barbara; Keating, Sean; Zechner, Marie; Haley, Chris; Porteous, David J; Hayward, Caroline; Yang, Jian; Knight, Julian; Summers, Charlotte; Shankar-Hari, Manu; Klenerman, Paul; Turtle, Lance; Ho, Antonia; Moore, Shona C; Hinds, Charles; Horby, Peter; Nichol, Alistair; Maslove, David; Ling, Lowell; McAuley, Danny; Montgomery, Hugh; Walsh, Timothy.

Nature ; 591(7848): 92-98, 2021 03.

Article in English | MEDLINE | ID: mdl-33307546

7.

Bio-catalyzed oxidation self-charging zinc-polymer batteries.

Pan, Jun; Liu, Yanhong; Yang, Jian; Wu, Jiawen; Fan, Hong Jin.

Proc Natl Acad Sci U S A ; 121(8): e2312870121, 2024 Feb 20.

Article in English | MEDLINE | ID: mdl-38349875

8.

mBAT-combo: A more powerful test to detect gene-trait associations from GWAS data.

Li, Ang; Liu, Shouye; Bakshi, Andrew; Jiang, Longda; Chen, Wenhan; Zheng, Zhili; Sullivan, Patrick F; Visscher, Peter M; Wray, Naomi R; Yang, Jian; Zeng, Jian.

Am J Hum Genet ; 110(1): 30-43, 2023 01 05.

Article in English | MEDLINE | ID: mdl-36608683

9.

BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets.

Manubens-Gil, Linus; Zhou, Zhi; Chen, Hanbo; Ramanathan, Arvind; Liu, Xiaoxiao; Liu, Yufeng; Bria, Alessandro; Gillette, Todd; Ruan, Zongcai; Yang, Jian; Radojevic, Miroslav; Zhao, Ting; Cheng, Li; Qu, Lei; Liu, Siqi; Bouchard, Kristofer E; Gu, Lin; Cai, Weidong; Ji, Shuiwang; Roysam, Badrinath; Wang, Ching-Wei; Yu, Hongchuan; Sironi, Amos; Iascone, Daniel Maxim; Zhou, Jie; Bas, Erhan; Conde-Sousa, Eduardo; Aguiar, Paulo; Li, Xiang; Li, Yujie; Nanda, Sumit; Wang, Yuan; Muresan, Leila; Fua, Pascal; Ye, Bing; He, Hai-Yan; Staiger, Jochen F; Peter, Manuel; Cox, Daniel N; Simonneau, Michel; Oberlaender, Marcel; Jefferis, Gregory; Ito, Kei; Gonzalez-Bellido, Paloma; Kim, Jinhyun; Rubel, Edwin; Cline, Hollis T; Zeng, Hongkui; Nern, Aljoscha; Chiang, Ann-Shyn.

Nat Methods ; 20(6): 824-835, 2023 Jun.

Article in English | MEDLINE | ID: mdl-37069271

10.

FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis.

Xu, Jing; Guo, Rongtian; Wen, Nasi; Li, Luping; Yi, Yong; Chen, Jingzhen; He, Zongyu; Yang, Jian; Xiao, Zhi-Xiong Jim; Niu, Mengmeng.

PLoS Biol ; 21(12): e3002446, 2023 Dec.

Article in English | MEDLINE | ID: mdl-38134227

11.

Deficiency of Transcription Factor Sp1 Contributes to Hypertrophic Cardiomyopathy.

Zhang, Fulei; Zhou, Huixing; Xue, Jinfeng; Zhang, Yuemei; Zhou, Liping; Leng, Junwei; Fang, Guojian; Liu, Yuanyuan; Wang, Yan; Liu, Hongyu; Wu, Yahan; Qi, Lingbin; Duan, Ran; He, Xiaoyu; Wang, Yan; Liu, Yi; Li, Li; Yang, Jian; Liang, Dandan; Chen, Yi-Han.

Circ Res ; 134(3): 290-306, 2024 02 02.

Article in English | MEDLINE | ID: mdl-38197258

12.

Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness.

Makowski, Carolina; Wang, Hao; Srinivasan, Anjali; Qi, Anna; Qiu, Yuqi; van der Meer, Dennis; Frei, Oleksandr; Zou, Jingjing; Visscher, Peter M; Yang, Jian; Chen, Chi-Hua.

Proc Natl Acad Sci U S A ; 120(11): e2214834120, 2023 03 14.

Article in English | MEDLINE | ID: mdl-36893272

13.

Transcriptome analysis with different leaf blades identifies the phloem-specific phosphate transporter OsPHO1;3 required for phosphate homeostasis in rice.

Yan, Meng; Xie, Mengyang; Chen, Wang; Si, Wen-Jing; Lin, Hong-Hui; Yang, Jian.

Plant J ; 118(3): 905-919, 2024 May.

Article in English | MEDLINE | ID: mdl-38251949

14.

Exploring pharmacological active ingredients of traditional Chinese medicine by pharmacotranscriptomic map in ITCM.

Tian, Saisai; Zhang, Jinbo; Yuan, Shunling; Wang, Qun; Lv, Chao; Wang, Jinxing; Fang, Jiansong; Fu, Lu; Yang, Jian; Zu, Xianpeng; Zhao, Jing; Zhang, Weidong.

Brief Bioinform ; 24(2)2023 03 19.

Article in English | MEDLINE | ID: mdl-36719094

15.

Single-cell immune profiling of mouse liver aging reveals Cxcl2+ macrophages recruit neutrophils to aggravate liver injury.

Liu, Yasong; Xiao, Jiaqi; Cai, Jianye; Li, Rong; Sui, Xin; Zhang, Jiebin; Lu, Tongyu; Chen, Haitian; Chen, Guihua; Li, Haibo; Jiang, Chenhao; Zhao, Xuegang; Xiao, Cuicui; Lei, Yunguo; Yao, Jia; Lv, Guo; Liang, Jinliang; Zhang, Yingcai; Yang, Jian-Rong; Zheng, Jun; Yang, Yang.

Hepatology ; 79(3): 589-605, 2024 Mar 01.

Article in English | MEDLINE | ID: mdl-37695548

16.

tModBase: deciphering the landscape of tRNA modifications and their dynamic changes from epitranscriptome data.

Lei, Hao-Tian; Wang, Zhang-Hao; Li, Bin; Sun, Yang; Mei, Shi-Qiang; Yang, Jian-Hua; Qu, Liang-Hu; Zheng, Ling-Ling.

Nucleic Acids Res ; 51(D1): D315-D327, 2023 01 06.

Article in English | MEDLINE | ID: mdl-36408909

17.

VCF2PCACluster: a simple, fast and memory-efficient tool for principal component analysis of tens of millions of SNPs.

He, Weiming; Xu, Lian; Wang, JingXian; Yue, Zhen; Jing, Yi; Tai, Shuaishuai; Yang, Jian; Fang, Xiaodong.

BMC Bioinformatics ; 25(1): 173, 2024 May 01.

Article in English | MEDLINE | ID: mdl-38693489

18.

Cartilage stem/progenitor cells-derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model.

Chen, Jing; Ni, Xiaohui; Yang, Jian; Yang, Hongwei; Liu, Xiaoyu; Chen, Minhao; Sun, Cheng; Wang, Youhua.

J Cell Mol Med ; 28(8): e18327, 2024 Apr.

Article in English | MEDLINE | ID: mdl-38661437

19.

Cardioprotective effects of asiaticoside against diabetic cardiomyopathy: Activation of the AMPK/Nrf2 pathway.

Xu, Chennian; Xia, Lin; Xu, Dengyue; Liu, Yang; Jin, Ping; Zhai, Mengen; Mao, Yu; Wang, Yiwei; Wen, Anguo; Yang, Jian; Yang, Lifang.

J Cell Mol Med ; 28(2): e18055, 2024 Jan.

Article in English | MEDLINE | ID: mdl-38113341

20.

Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis.

Wu, Yichen; Wang, Haobin; Huo, Ying; Yan, Bingfang; Honda, Hiroaki; Liu, Wei; Yang, Jian.

J Biol Chem ; 299(3): 102982, 2023 03.

Article in English | MEDLINE | ID: mdl-36739947

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