Search | Virtual Health Library

1.

A method for colocalizing lineage tracing reporter and RNAscope signals on skeletal tissue section.

Yang, Huiliang; Wang, Liang; Turajane, Kathleen; Wang, Lijun; Yang, Wentian.

RNA ; 2020 Dec 04.

Article in English | MEDLINE | ID: mdl-33277438

2.

SHP2 regulates the development of intestinal epithelium by modifying OSTERIX⁺ crypt stem cell self-renewal and proliferation.

Wang, Lijun; Moore, Douglas C; Huang, Jiahui; Wang, Yuhong; Zhao, Hu; D-H Yue, Jerry; Jackson, Cynthia L; Quesenberry, Peter J; Cao, Weibiao; Yang, Wentian.

FASEB J ; 35(1): e21106, 2021 01.

Article in English | MEDLINE | ID: mdl-33165997

3.

GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2.

Li, Zhi-Wei; Sun, Beicheng; Gong, Ting; Guo, Sheng; Zhang, Jianhua; Wang, Junlong; Sugawara, Atsushi; Jiang, Meisheng; Yan, Junjun; Gurary, Alexandra; Zheng, Xin; Gao, Bifeng; Xiao, Shu-Yuan; Chen, Wenlian; Ma, Chi; Farrar, Christine; Zhu, Chenjun; Chan, Owen T M; Xin, Can; Winnicki, Andrew; Winnicki, John; Tang, Mingxin; Park, Ryan; Winnicki, Mary; Diener, Katrina; Wang, Zhanwei; Liu, Qicai; Chu, Catherine H; Arter, Zhaohui L; Yue, Peibin; Alpert, Lindsay; Hui, George S; Fei, Peiwen; Turkson, James; Yang, Wentian; Wu, Guangyu; Tao, Ailin; Ramos, Joe W; Moisyadi, Stefan; Holcombe, Randall F; Jia, Wei; Birnbaumer, Lutz; Zhou, Xiqiao; Chu, Wen-Ming.

Gastroenterology ; 156(8): 2297-2312, 2019 06.

Article in English | MEDLINE | ID: mdl-30836096

4.

A ERK/RSK-mediated negative feedback loop regulates M-CSF-evoked PI3K/AKT activation in macrophages.

Wang, Lijun; Iorio, Caterina; Yan, Kevin; Yang, Howard; Takeshita, Sunao; Kang, Sumin; Neel, Benjamin G; Yang, Wentian.

FASEB J ; 32(2): 875-887, 2018 02.

Article in English | MEDLINE | ID: mdl-29046360

5.

Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling.

Yang, Wentian; Wang, Jianguo; Moore, Douglas C; Liang, Haipei; Dooner, Mark; Wu, Qian; Terek, Richard; Chen, Qian; Ehrlich, Michael G; Quesenberry, Peter J; Neel, Benjamin G.

Nature ; 499(7459): 491-5, 2013 Jul 25.

Article in English | MEDLINE | ID: mdl-23863940

6.

Gain-of-function mutations of Ptpn11 (Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignancies.

Liu, Xia; Zheng, Hong; Li, Xiaobo; Wang, Siying; Meyerson, Howard J; Yang, Wentian; Neel, Benjamin G; Qu, Cheng-Kui.

Proc Natl Acad Sci U S A ; 113(4): 984-9, 2016 Jan 26.

Article in English | MEDLINE | ID: mdl-26755576

7.

Iron turns to wild when the transferrin is away.

Yang, Wentian.

Blood ; 136(6): 649-650, 2020 08 06.

Article in English | MEDLINE | ID: mdl-32761217

8.

SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates.

Bowen, Margot E; Ayturk, Ugur M; Kurek, Kyle C; Yang, Wentian; Warman, Matthew L.

PLoS Genet ; 10(5): e1004364, 2014.

Article in English | MEDLINE | ID: mdl-24875294

9.

SHP2 regulates osteoclastogenesis by promoting preosteoclast fusion.

Zhou, Yi; Mohan, Aron; Moore, Douglas C; Lin, Liangjun; Zhou, Frank Li; Cao, Jay; Wu, Qian; Qin, Yi-Xian; Reginato, Anthony M; Ehrlich, Michael G; Yang, Wentian.

FASEB J ; 29(5): 1635-45, 2015 May.

Article in English | MEDLINE | ID: mdl-25593124

10.

Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum.

Li, Kairong; Leung, Alan W; Guo, Qiuxia; Yang, Wentian; Li, James Y H.

J Neurosci ; 34(3): 922-31, 2014 Jan 15.

Article in English | MEDLINE | ID: mdl-24431450

11.

Mechanical activation of mammalian target of rapamycin pathway is required for cartilage development.

Guan, Yingjie; Yang, Xu; Yang, Wentian; Charbonneau, Cherie; Chen, Qian.

FASEB J ; 28(10): 4470-81, 2014 Oct.

Article in English | MEDLINE | ID: mdl-25002119

12.

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.

Chan, Gordon; Cheung, Laurene S; Yang, Wentian; Milyavsky, Michael; Sanders, Ashley D; Gu, Shengqing; Hong, Wan Xing; Liu, Aurora X; Wang, Xiaonan; Barbara, Mary; Sharma, Tarun; Gavin, Joehleen; Kutok, Jeffery L; Iscove, Norman N; Shannon, Kevin M; Dick, John E; Neel, Benjamin G; Braun, Benjamin S.

Blood ; 117(16): 4253-61, 2011 Apr 21.

Article in English | MEDLINE | ID: mdl-21398220

13.

LRP5, Bone Mass Polymorphisms and Skeletal Disorders.

Littman, Jake; Yang, Wentian; Olansen, Jon; Phornphutkul, Chanika; Aaron, Roy K.

Genes (Basel) ; 14(10)2023 09 23.

Article in English | MEDLINE | ID: mdl-37895195

14.

Protein tyrosine phosphatases in skeletal development and diseases.

Yang, Huiliang; Wang, Lijun; Shigley, Christian; Yang, Wentian.

Bone Res ; 10(1): 10, 2022 Jan 28.

Article in English | MEDLINE | ID: mdl-35091552

15.

Altered glucose homeostasis in mice with liver-specific deletion of Src homology phosphatase 2.

Matsuo, Kosuke; Delibegovic, Mirela; Matsuo, Izumi; Nagata, Naoto; Liu, Siming; Bettaieb, Ahmed; Xi, Yannan; Araki, Kazushi; Yang, Wentian; Kahn, Barbara B; Neel, Benjamin G; Haj, Fawaz G.

J Biol Chem ; 285(51): 39750-8, 2010 Dec 17.

Article in English | MEDLINE | ID: mdl-20841350

16.

An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival.

Yang, Wentian; Klaman, Lori D; Chen, Binbin; Araki, Toshiyuki; Harada, Hisashi; Thomas, Sheila M; George, Elizabeth L; Neel, Benjamin G.

Dev Cell ; 10(3): 317-27, 2006 Mar.

Article in English | MEDLINE | ID: mdl-16516835

17.

Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis.

Chan, Gordon; Kalaitzidis, Demetrios; Usenko, Tatiana; Kutok, Jeffery L; Yang, Wentian; Mohi, M Golam; Neel, Benjamin G.

Blood ; 113(18): 4414-24, 2009 Apr 30.

Article in English | MEDLINE | ID: mdl-19179468

18.

SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth.

Fornaro, Mara; Burch, Peter M; Yang, Wentian; Zhang, Lei; Hamilton, Claire E; Kim, Jung H; Neel, Benjamin G; Bennett, Anton M.

J Cell Biol ; 175(1): 87-97, 2006 Oct 09.

Article in English | MEDLINE | ID: mdl-17015617

19.

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.

Araki, Toshiyuki; Mohi, M Golam; Ismat, Fraz A; Bronson, Roderick T; Williams, Ifor R; Kutok, Jeffery L; Yang, Wentian; Pao, Lily I; Gilliland, D Gary; Epstein, Jonathan A; Neel, Benjamin G.

Nat Med ; 10(8): 849-57, 2004 Aug.

Article in English | MEDLINE | ID: mdl-15273746

20.

Targeted Ptpn11 deletion in mice reveals the essential role of SHP2 in osteoblast differentiation and skeletal homeostasis.

Wang, Lijun; Yang, Huiliang; Huang, Jiahui; Pei, Shaopeng; Wang, Liyun; Feng, Jian Q; Jing, Dian; Zhao, Hu; Kronenberg, Henry M; Moore, Douglas C; Yang, Wentian.

Bone Res ; 9(1): 6, 2021 Jan 27.

Article in English | MEDLINE | ID: mdl-33500396

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