Search | Virtual Health Library

1.

The mechanisms and roles of selective autophagy in mammals.

Vargas, Jose Norberto S; Hamasaki, Maho; Kawabata, Tsuyoshi; Youle, Richard J; Yoshimori, Tamotsu.

Nat Rev Mol Cell Biol ; 24(3): 167-185, 2023 03.

Article in English | MEDLINE | ID: mdl-36302887

2.

Mitochondrial Quality Control and Restraining Innate Immunity.

Moehlman, Andrew T; Youle, Richard J.

Annu Rev Cell Dev Biol ; 36: 265-289, 2020 10 06.

Article in English | MEDLINE | ID: mdl-33021820

3.

Integrating the response to stressed mitochondria.

Dine, Elliot; Youle, Richard J.

Mol Cell ; 84(6): 995-997, 2024 Mar 21.

Article in English | MEDLINE | ID: mdl-38518749

4.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.

Le Guerroué, François; Bunker, Eric N; Rosencrans, William M; Nguyen, Jack T; Basar, Mohammed A; Werner, Achim; Chou, Tsui-Fen; Wang, Chunxin; Youle, Richard J.

Mol Cell ; 83(6): 927-941.e8, 2023 03 16.

Article in English | MEDLINE | ID: mdl-36898370

5.

Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain.

Sarraf, Shireen A; Shah, Hetal V; Kanfer, Gil; Pickrell, Alicia M; Holtzclaw, Lynne A; Ward, Michael E; Youle, Richard J.

Mol Cell ; 80(5): 779-795.e10, 2020 12 03.

Article in English | MEDLINE | ID: mdl-33207181

6.

Nix interacts with WIPI2 to induce mitophagy.

Bunker, Eric N; Le Guerroué, François; Wang, Chunxin; Strub, Marie-Paule; Werner, Achim; Tjandra, Nico; Youle, Richard J.

EMBO J ; 42(22): e113491, 2023 Nov 15.

Article in English | MEDLINE | ID: mdl-37621214

7.

Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1.

Sekine, Shiori; Wang, Chunxin; Sideris, Dionisia P; Bunker, Eric; Zhang, Zhe; Youle, Richard J.

Mol Cell ; 73(5): 1028-1043.e5, 2019 03 07.

Article in English | MEDLINE | ID: mdl-30733118

8.

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.

Vargas, Jose Norberto S; Wang, Chunxin; Bunker, Eric; Hao, Ling; Maric, Dragan; Schiavo, Giampietro; Randow, Felix; Youle, Richard J.

Mol Cell ; 74(2): 347-362.e6, 2019 04 18.

Article in English | MEDLINE | ID: mdl-30853401

9.

PINK1 and Parkin flag Miro to direct mitochondrial traffic.

Kane, Lesley A; Youle, Richard J.

Cell ; 147(4): 721-3, 2011 Nov 11.

Article in English | MEDLINE | ID: mdl-22078873

10.

Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol.

Edlich, Frank; Banerjee, Soojay; Suzuki, Motoshi; Cleland, Megan M; Arnoult, Damien; Wang, Chunxin; Neutzner, Albert; Tjandra, Nico; Youle, Richard J.

Cell ; 145(1): 104-16, 2011 Apr 01.

Article in English | MEDLINE | ID: mdl-21458670

11.

Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage.

Moehlman, Andrew T; Kanfer, Gil; Youle, Richard J.

PLoS Genet ; 19(7): e1010828, 2023 07.

Article in English | MEDLINE | ID: mdl-37440574

12.

Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain.

Sarraf, Shireen A; Shah, Hetal V; Kanfer, Gil; Pickrell, Alicia M; Holtzclaw, Lynne A; Ward, Michael E; Youle, Richard J.

Mol Cell ; 82(7): 1383-1385, 2022 Apr 07.

Article in English | MEDLINE | ID: mdl-35395199

13.

Parkin and PINK1 mitigate STING-induced inflammation.

Sliter, Danielle A; Martinez, Jennifer; Hao, Ling; Chen, Xi; Sun, Nuo; Fischer, Tara D; Burman, Jonathon L; Li, Yan; Zhang, Zhe; Narendra, Derek P; Cai, Huaibin; Borsche, Max; Klein, Christine; Youle, Richard J.

Nature ; 561(7722): 258-262, 2018 09.

Article in English | MEDLINE | ID: mdl-30135585

14.

The Mitochondrial Basis of Aging.

Sun, Nuo; Youle, Richard J; Finkel, Toren.

Mol Cell ; 61(5): 654-666, 2016 Mar 03.

Article in English | MEDLINE | ID: mdl-26942670

15.

Mechanisms of mitophagy.

Youle, Richard J; Narendra, Derek P.

Nat Rev Mol Cell Biol ; 12(1): 9-14, 2011 Jan.

Article in English | MEDLINE | ID: mdl-21179058

16.

Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins.

Stolz, Alexandra; Putyrski, Mateusz; Kutle, Ivana; Huber, Jessica; Wang, Chunxin; Major, Viktória; Sidhu, Sachdev S; Youle, Richard J; Rogov, Vladimir V; Dötsch, Volker; Ernst, Andreas; Dikic, Ivan.

EMBO J ; 36(4): 549-564, 2017 02 15.

Article in English | MEDLINE | ID: mdl-28028054

17.

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism.

Borsche, Max; König, Inke R; Delcambre, Sylvie; Petrucci, Simona; Balck, Alexander; Brüggemann, Norbert; Zimprich, Alexander; Wasner, Kobi; Pereira, Sandro L; Avenali, Micol; Deuschle, Christian; Badanjak, Katja; Ghelfi, Jenny; Gasser, Thomas; Kasten, Meike; Rosenstiel, Philip; Lohmann, Katja; Brockmann, Kathrin; Valente, Enza Maria; Youle, Richard J; Grünewald, Anne; Klein, Christine.

Brain ; 143(10): 3041-3051, 2020 10 01.

Article in English | MEDLINE | ID: mdl-33029617

18.

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.

Lazarou, Michael; Sliter, Danielle A; Kane, Lesley A; Sarraf, Shireen A; Wang, Chunxin; Burman, Jonathon L; Sideris, Dionisia P; Fogel, Adam I; Youle, Richard J.

Nature ; 524(7565): 309-314, 2015 Aug 20.

Article in English | MEDLINE | ID: mdl-26266977

19.

Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase Î³.

Samstag, Colby L; Hoekstra, Jake G; Huang, Chiu-Hui; Chaisson, Mark J; Youle, Richard J; Kennedy, Scott R; Pallanck, Leo J.

PLoS Genet ; 14(11): e1007805, 2018 11.

Article in English | MEDLINE | ID: mdl-30452458

20.

Neurolastin, a dynamin family GTPase, translocates to mitochondria upon neuronal stress and alters mitochondrial morphology in vivo.

Lomash, Richa Madan; Petralia, Ronald S; Holtzclaw, Lynne A; Tsuda, Mumeko C; Wang, Ya-Xian; Badger, John D; Cameron, Heather A; Youle, Richard J; Roche, Katherine W.

J Biol Chem ; 294(30): 11498-11512, 2019 07 26.

Article in English | MEDLINE | ID: mdl-31177092

Virtual Health Library

United States - Mexico Border

Your selection (0)

Export format:

Export:

The mechanisms and roles of selective autophagy in mammals.

Mitochondrial Quality Control and Restraining Innate Immunity.

Integrating the response to stressed mitochondria.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.

Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain.

Nix interacts with WIPI2 to induce mitophagy.

Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1.

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.

PINK1 and Parkin flag Miro to direct mitochondrial traffic.

Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol.

Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage.

Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain.

Parkin and PINK1 mitigate STING-induced inflammation.

The Mitochondrial Basis of Aging.

Mechanisms of mitophagy.

Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins.

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism.

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.

Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase Î³.

Neurolastin, a dynamin family GTPase, translocates to mitochondria upon neuronal stress and alters mitochondrial morphology in vivo.