Search | Virtual Health Library

1.

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling.

Yu, Fa-Xing; Zhao, Bin; Panupinthu, Nattapon; Jewell, Jenna L; Lian, Ian; Wang, Lloyd H; Zhao, Jiagang; Yuan, Haixin; Tumaneng, Karen; Li, Hairi; Fu, Xiang-Dong; Mills, Gordon B; Guan, Kun-Liang.

Cell ; 187(6): 1563-1564, 2024 Mar 14.

Article in English | MEDLINE | ID: mdl-38490182

2.

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer.

Yu, Fa-Xing; Zhao, Bin; Guan, Kun-Liang.

Cell ; 163(4): 811-28, 2015 Nov 05.

Article in English | MEDLINE | ID: mdl-26544935

3.

Alternative Wnt Signaling Activates YAP/TAZ.

Park, Hyun Woo; Kim, Young Chul; Yu, Bo; Moroishi, Toshiro; Mo, Jung-Soon; Plouffe, Steven W; Meng, Zhipeng; Lin, Kimberly C; Yu, Fa-Xing; Alexander, Caroline M; Wang, Cun-Yu; Guan, Kun-Liang.

Cell ; 162(4): 780-94, 2015 Aug 13.

Article in English | MEDLINE | ID: mdl-26276632

4.

WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy.

Qi, Sixian; Zhu, Yuwen; Liu, Xincheng; Li, Pengyue; Wang, Yebin; Zeng, Yan; Yu, Aijuan; Wang, Yu; Sha, Zhao; Zhong, Zhenxing; Zhu, Rui; Yuan, Haixin; Ye, Dan; Huang, Shenglin; Ling, Chen; Xu, Yanhui; Zhou, Dawang; Zhang, Lei; Yu, Fa-Xing.

Mol Cell ; 82(10): 1850-1864.e7, 2022 05 19.

Article in English | MEDLINE | ID: mdl-35429439

5.

Proteolytic activation of angiomotin by DDI2 promotes angiogenesis.

Wang, Yu; Zhu, Yuwen; Wang, Yebin; Chang, Yue; Geng, Fang; Ma, Mingyue; Gu, Yuan; Yu, Aijuan; Zhu, Rui; Yu, Pengcheng; Sha, Zhao; Qi, Sixian; Li, Jian; Zhao, Wencao; Pan, Weijun; Zhang, Ruilin; Yu, Fa-Xing.

EMBO J ; 42(15): e112900, 2023 08 01.

Article in English | MEDLINE | ID: mdl-37350545

6.

Two Hippo signaling modules orchestrate liver size and tumorigenesis.

Qi, Sixian; Zhong, Zhenxing; Zhu, Yuwen; Wang, Yebin; Ma, Mingyue; Wang, Yu; Liu, Xincheng; Jin, Ruxin; Jiao, Zhihan; Zhu, Rui; Sha, Zhao; Dang, Kyvan; Liu, Ying; Lim, Dae-Sik; Mao, Junhao; Zhang, Lei; Yu, Fa-Xing.

EMBO J ; 42(11): e112126, 2023 06 01.

Article in English | MEDLINE | ID: mdl-36919851

7.

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.

Yu, Fa-Xing; Zhao, Bin; Panupinthu, Nattapon; Jewell, Jenna L; Lian, Ian; Wang, Lloyd H; Zhao, Jiagang; Yuan, Haixin; Tumaneng, Karen; Li, Hairi; Fu, Xiang-Dong; Mills, Gordon B; Guan, Kun-Liang.

Cell ; 150(4): 780-91, 2012 Aug 17.

Article in English | MEDLINE | ID: mdl-22863277

8.

Angiomotin family proteins in the Hippo signaling pathway.

Wang, Yu; Yu, Fa-Xing.

Bioessays ; : e2400076, 2024 May 17.

Article in English | MEDLINE | ID: mdl-38760875

9.

RAP2 mediates mechanoresponses of the Hippo pathway.

Meng, Zhipeng; Qiu, Yunjiang; Lin, Kimberly C; Kumar, Aditya; Placone, Jesse K; Fang, Cao; Wang, Kuei-Chun; Lu, Shicong; Pan, Margaret; Hong, Audrey W; Moroishi, Toshiro; Luo, Min; Plouffe, Steven W; Diao, Yarui; Ye, Zhen; Park, Hyun Woo; Wang, Xiaoqiong; Yu, Fa-Xing; Chien, Shu; Wang, Cun-Yu; Ren, Bing; Engler, Adam J; Guan, Kun-Liang.

Nature ; 560(7720): 655-660, 2018 08.

Article in English | MEDLINE | ID: mdl-30135582

10.

NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition.

Yuan, Hai-Xin; Wang, Zhen; Yu, Fa-Xing; Li, Fulong; Russell, Ryan C; Jewell, Jenna L; Guan, Kun-Liang.

Genes Dev ; 29(22): 2362-76, 2015 Nov 15.

Article in English | MEDLINE | ID: mdl-26588989

11.

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis.

Moroishi, Toshiro; Park, Hyun Woo; Qin, Baodong; Chen, Qian; Meng, Zhipeng; Plouffe, Steven W; Taniguchi, Koji; Yu, Fa-Xing; Karin, Michael; Pan, Duojia; Guan, Kun-Liang.

Genes Dev ; 29(12): 1271-84, 2015 Jun 15.

Article in English | MEDLINE | ID: mdl-26109050

12.

Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis.

Sun, Renqiang; Zhang, Zhiyong; Bao, Ruoxuan; Guo, Xiaozhen; Gu, Yuan; Yang, Wenjing; Wei, Jinsong; Chen, Xinyu; Tong, Lingfeng; Meng, Jian; Zhong, Chen; Zhang, Cheng; Zhang, Jinye; Sun, Yiping; Ling, Chen; Tong, Xuemei; Yu, Fa-Xing; Yu, Hongxiu; Qu, Weifeng; Zhao, Bing; Guo, Wei; Qian, Maoxiang; Saiyin, Hexige; Liu, Ying; Liu, Rong-Hua; Xie, Cen; Liu, Weiren; Xiong, Yue; Guan, Kun-Liang; Shi, Yinghong; Wang, Pu; Ye, Dan.

J Hepatol ; 77(2): 453-466, 2022 08.

Article in English | MEDLINE | ID: mdl-35292350

13.

Two Hippo signaling modules orchestrate liver size and tumorigenesis.

Qi, Sixian; Zhong, Zhenxing; Zhu, Yuwen; Wang, Yebin; Ma, Mingyue; Wang, Yu; Liu, Xincheng; Jin, Ruxin; Jiao, Zhihan; Zhu, Rui; Sha, Zhao; Dang, Kyvan; Liu, Ying; Lim, Dae-Sik; Mao, Junhao; Zhang, Lei; Yu, Fa-Xing.

EMBO J ; 42(22): e115749, 2023 Nov 15.

Article in English | MEDLINE | ID: mdl-37849424

14.

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis.

Fu, Lina; Hu, Yuqiong; Song, Moshi; Liu, Zunpeng; Zhang, Weiqi; Yu, Fa-Xing; Wu, Jun; Wang, Si; Izpisua Belmonte, Juan Carlos; Chan, Piu; Qu, Jing; Tang, Fuchou; Liu, Guang-Hui.

PLoS Biol ; 17(4): e3000201, 2019 04.

Article in English | MEDLINE | ID: mdl-30933975

15.

An alternatively transcribed TAZ variant negatively regulates JAK-STAT signaling.

Fang, Chuantao; Li, Jian; Qi, Sixian; Lei, Yubin; Zeng, Yan; Yu, Pengcheng; Hu, Zhaolan; Zhou, Yufeng; Wang, Yulong; Dai, Ruping; Li, Jin; Huang, Shenglin; Xu, Pinglong; Chen, Kang; Ding, Chen; Yu, Fa-Xing.

EMBO Rep ; 20(6)2019 06.

Article in English | MEDLINE | ID: mdl-30979708

16.

A gp130-Src-YAP module links inflammation to epithelial regeneration.

Taniguchi, Koji; Wu, Li-Wha; Grivennikov, Sergei I; de Jong, Petrus R; Lian, Ian; Yu, Fa-Xing; Wang, Kepeng; Ho, Samuel B; Boland, Brigid S; Chang, John T; Sandborn, William J; Hardiman, Gary; Raz, Eyal; Maehara, Yoshihiko; Yoshimura, Akihiko; Zucman-Rossi, Jessica; Guan, Kun-Liang; Karin, Michael.

Nature ; 519(7541): 57-62, 2015 Mar 05.

Article in English | MEDLINE | ID: mdl-25731159

17.

The Hippo pathway: regulators and regulations.

Yu, Fa-Xing; Guan, Kun-Liang.

Genes Dev ; 27(4): 355-71, 2013 Feb 15.

Article in English | MEDLINE | ID: mdl-23431053

18.

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation.

Yu, Fa-Xing; Zhang, Yifan; Park, Hyun Woo; Jewell, Jenna L; Chen, Qian; Deng, Yaoting; Pan, Duojia; Taylor, Susan S; Lai, Zhi-Chun; Guan, Kun-Liang.

Genes Dev ; 27(11): 1223-32, 2013 Jun 01.

Article in English | MEDLINE | ID: mdl-23752589

19.

Regulation of TP73 transcription by Hippo-YAP signaling.

Wen, Zichao; Wang, Yu; Qi, Sixian; Ma, Mingyue; Li, Jian; Yu, Fa-Xing.

Biochem Biophys Res Commun ; 531(2): 96-104, 2020 10 15.

Article in English | MEDLINE | ID: mdl-32773110

20.

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs).

Mo, Jung-Soon; Yu, Fa-Xing; Gong, Rui; Brown, Joan Heller; Guan, Kun-Liang.

Genes Dev ; 26(19): 2138-43, 2012 Oct 01.

Article in English | MEDLINE | ID: mdl-22972936

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Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling.

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer.

Alternative Wnt Signaling Activates YAP/TAZ.

WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy.

Proteolytic activation of angiomotin by DDI2 promotes angiogenesis.

Two Hippo signaling modules orchestrate liver size and tumorigenesis.

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.

Angiomotin family proteins in the Hippo signaling pathway.

RAP2 mediates mechanoresponses of the Hippo pathway.

NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition.

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis.

Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis.

Two Hippo signaling modules orchestrate liver size and tumorigenesis.

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis.

An alternatively transcribed TAZ variant negatively regulates JAK-STAT signaling.

A gp130-Src-YAP module links inflammation to epithelial regeneration.

The Hippo pathway: regulators and regulations.

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation.

Regulation of TP73 transcription by Hippo-YAP signaling.

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs).