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1.
Skeletal Radiol ; 52(10): 1873-1886, 2023 Oct.
Article in English | MEDLINE | ID: mdl-36245007

ABSTRACT

Facet joint (FJ) disease is a common cause of axial low back pain with many minimally invasive image-guided treatment options. This article discusses fluoroscopic and CT-guided intraarticular FJ injections, medial branch (MB) radiofrequency ablation (RFA), and lumbar facet synovial cyst (LFSC) aspiration, rupture, or fenestration. Additionally, the article will highlight medial branch blocks (MBBs) utilized to diagnose facet-mediated pain and to predict outcomes to RFA.


Subject(s)
Low Back Pain , Radiofrequency Ablation , Synovial Cyst , Zygapophyseal Joint , Humans , Zygapophyseal Joint/diagnostic imaging , Zygapophyseal Joint/surgery , Low Back Pain/diagnostic imaging , Low Back Pain/surgery , Low Back Pain/etiology , Radiofrequency Ablation/adverse effects , Synovial Cyst/diagnostic imaging , Synovial Cyst/surgery , Lumbosacral Region
2.
BMC Musculoskelet Disord ; 23(1): 1005, 2022 Nov 22.
Article in English | MEDLINE | ID: mdl-36419039

ABSTRACT

BACKGROUND: Acromioclavicular (AC) joint cysts are relatively rare. There are two distinct etiologies of AC cysts. Type 1 is isolated to the AC joint, while type 2, is related to a tear or rupture of the rotator cuff (RC). The disease is usually a rare result of advanced AC joint arthritis or RC-tear arthropathy. Patients may present with signs and symptoms of RC impingement and tear. Conservative management may be used initially in asymptomatic individuals who are also not concerned with cosmesis. Aspiration and steroid injection of the cyst has been reported as one method of non-surgical management of these lesions, however, there is a high rate of recurrence. CASE PRESENTATION: We report a case of A 72-year-old right-handed female with past medical history of type two diabetes mellitus, chronic smoking, and a prior right RC repair with distal clavicle resection who presented with an AC joint cyst complicated by a draining fistula as a result of cyst aspiration and steroid injection. Due to the persistent drainage of the cyst and concern for infection, the patient was treated with a staged reverse shoulder arthroplasty given the setting of an irreparable rotator cuff tear and end-stage cuff-tear arthropathy. CONCLUSION: This case demonstrates an important complication of persistent draining fistula resulting from AC joint cyst aspiration and steroid injection in the setting of advanced RC-tear arthropathy. In immunocompromised patients, staged reverse shoulder arthroplasty should be considered for treatment of these draining fistulas especially when the concern for periprosthetic infection is high.


Subject(s)
Arthroplasty, Replacement, Shoulder , Cysts , Fistula , Rotator Cuff Tear Arthropathy , Humans , Female , Aged , Cysts/complications , Cysts/diagnostic imaging , Inflammation , Steroids
3.
Acta Neurochir (Wien) ; 163(2): 343-350, 2021 02.
Article in English | MEDLINE | ID: mdl-32291592

ABSTRACT

BACKGROUND: Gamma Knife radiosurgery (GKRS) has been proven to be a successful primary treatment for metastatic brain tumors (BM). BM can come in cystic lesions and are often too large for GKRS. An alternative approach to treat cystic BM is stereotactic cyst aspiration (SCA) for volume reduction, making it suitable for GKRS afterwards. OBJECTIVE: Our objective is evaluation of volumetric reduction after SCA, tumor control, and complications after SCA directly followed by GKRS. METHODS: We performed a retrospective analysis of all patients who underwent SCA directly followed by GKRS at the Gamma Knife Center of the Elisabeth-Tweesteden Hospital in Tilburg between 2002 and 2015. In total, 54 patients had undergone this combined approach. Two patients were excluded because of prior intracranial treatment. The other 52 patients were included for analysis. RESULTS: SCA resulted in a mean volumetric reduction of 56.5% (range 5.50-87.00%). In 83.6% of the tumors (46 tumors), SCA led to sufficient volumetric reduction making GKRS possible. The overall local tumor control (OLTC) of the aspirated lesions post-GKRS was 60.9% (28 out of 46 tumors). Median progression-free survival (PFS) and overall survival (OS) for all patients were 3 (range 5 days-14 months) and 12 months (range 5 days-58 months), respectively. Leptomeningeal disease was reported in 5 (9.6%) cases. CONCLUSION: SCA directly followed by GKRS is an effective and time-efficient treatment for large cystic BM in selected patients in which surgery is contraindicated and those with deeply located lesions.


Subject(s)
Brain Neoplasms/secondary , Brain Neoplasms/surgery , Adult , Aged , Aged, 80 and over , Brain Neoplasms/mortality , Cysts/mortality , Cysts/surgery , Female , Humans , Male , Meningeal Neoplasms/surgery , Middle Aged , Progression-Free Survival , Radiosurgery/methods , Retrospective Studies , Suction , Treatment Outcome
4.
Urol Int ; 101(3): 366-368, 2018.
Article in English | MEDLINE | ID: mdl-28494441

ABSTRACT

Parapelvic cysts originate in the renal parenchyma and extend into the renal sinus. A series of 3 patients with symptomatic obstructing parapelvic cysts is described, 2 with acute presentations, and 1 with chronic symptoms. In 2 of the 3 cases, there was a significant delay in establishing a diagnosis. Although one individual was successfully managed by image-guided cyst aspiration, the second patient required repeated aspiration due to cyst re-accumulation. A high index of clinical suspicion and a combination of imaging modalities, including serial ultrasound, excretory-phase CT, and MAG3 renogram, are necessary to establish the diagnosis and monitor response to treatment.


Subject(s)
Kidney Diseases, Cystic/therapy , Kidney Pelvis/pathology , Tomography, X-Ray Computed , Ultrasonography , Ureteral Diseases/therapy , Cysts/therapy , Humans , Hydronephrosis/pathology , Inflammation , Kidney/immunology , Kidney/pathology , Kidney Diseases, Cystic/diagnosis , Male , Pain/diagnosis , Radioisotope Renography , Treatment Outcome , Ureteral Diseases/diagnosis , Urography
5.
Ceska Gynekol ; 82(6): 450-454, 2017.
Article in Cs | MEDLINE | ID: mdl-29302978

ABSTRACT

OBJECTIVE: The study was designed to prove the safety of simple cyst aspiration instead of the current treatment by laparoscopy. DESIGN: Retrospective analysis. SETTING: Fertimed Olomouc, Infertility Center. METHODS: We are presenting our experience with the aspiration of follicles (group A) and a functional cyst (group B, C). We are evaluating a number of complications in all groups, anaesthesia versus analgesia in group B, C and the cytological examination of fluid from the function cyst in group C. RESULTS: In 2,744 aspirations we detected 0.0004% small complications (vaginal wall bleeding) and 0.0004% major complications (laparoscopy, cystoscopy). No single cytological examination was suspect in the simple ovarian function cyst. CONCLUSION: Aspiration of a simple functional cyst is the first step of the treatment. It is a simple procedure. For patients it is comfortable and safe. In a simple cyst, we do not find suspect cells.


Subject(s)
Laparoscopy , Minimally Invasive Surgical Procedures/methods , Ovarian Cysts/surgery , Female , Humans , Retrospective Studies
6.
Gynecol Endocrinol ; 32(7): 562-5, 2016 Jul.
Article in English | MEDLINE | ID: mdl-26850271

ABSTRACT

The primary objective of this study is to investigate the effect of transvaginal ultrasonogram (TVUS)-guided cyst aspiration or gonadotropin releasing hormone antagonist (GnRH-ant) administration for the management of solitary ovarian cysts detected at the start of in vitro fertilization (IVF) cycles on the outcomes of the same cycles. This is a single-center, retrospective, cohort study of patients who had TVUS-guided cyst aspiration or GnRH-ant treatment for ovarian cysts detected at the start of IVF during a 5-year period. Four hundred and three patients met inclusion criteria: 41 (10.2%) underwent cyst aspiration and 362 (89.2%) were treated with GnRH-ant. There was no difference in the demographics or baseline IVF cycle characteristics of the two groups. Patients treated with GnRH-ant had a longer duration of ovarian stimulation (10.8 ± 3.45 days versus 9.05 ± 4.06 days, p = 0.003) and required higher gonadotropin doses (3887.7 ± 1097.8 IU versus 3293.7 ± 990.5 IU; p = 0.01) compared with the cyst aspiration group. There was no difference in the clinical pregnancy (43.9% versus 41.4%), spontaneous miscarriage (9.76% versus 8.01%) and live birth (34.1% versus 33.4%) rates between the groups. Our findings suggest that cyst aspiration is comparable to GnRH-ant administration for the management of solitary ovarian cysts detected at the start of IVF cycles.


Subject(s)
Biopsy, Needle/methods , Fertilization in Vitro/methods , Gonadotropin-Releasing Hormone/antagonists & inhibitors , Hormone Antagonists/therapeutic use , Outcome Assessment, Health Care , Ovarian Cysts , Adult , Endosonography , Female , Humans , Ovarian Cysts/diagnostic imaging , Ovarian Cysts/drug therapy , Ovarian Cysts/surgery , Pregnancy , Retrospective Studies
7.
J Neurosurg Case Lessons ; 8(16)2024 Oct 14.
Article in English | MEDLINE | ID: mdl-39401457

ABSTRACT

BACKGROUND: Resection of glioblastoma (GBM) in eloquent regions depends on functional mapping to limit perioperative neurological morbidity. When neurological deficits preclude reliable mapping, neurosurgeons should explore potential mitigation strategies. The authors present the case of a patient with a large left cystic temporoinsular GBM and aphasia, for whom the authors used intraoperative language mapping and a staged approach to enable safe tumor resection. OBSERVATIONS: A 49-year-old female presented with progressive mixed aphasia for 1 month and new-onset right facial droop. Magnetic resonance imaging (MRI) revealed a large, heterogeneously enhancing, left temporoinsular tumor with a significant cystic component. Her aphasia was profound, and resection without reliable language mapping was deemed unsafe. An initial stereotactic tumoral cyst aspiration was performed, which reduced local mass effect and improved her language function. Cyst decompression thereby enabled both task-based functional MRI and intraoperative awake speech mapping, resulting in a safe resection of her GBM. LESSONS: Safe resection of eloquently localized GBM is compromised when neurological deficits prohibit intraoperative functional mapping. This case demonstrates a mitigation strategy specific to cystic lesions in which an initial-stage stereotactic cyst aspiration is aimed at generating sufficient interval neurological improvement, such that intraoperative functional mapping can be performed during a second-stage resection. https://thejns.org/doi/10.3171/CASE24362.

8.
Surg Neurol Int ; 15: 65, 2024.
Article in English | MEDLINE | ID: mdl-38468664

ABSTRACT

Background: Lumbar synovial cysts (LSC), best diagnosed on MR studies, may cause symptoms/signs ranging from unilateral radiculopathy to cauda equina compressive syndromes. Attempts at percutaneous treatment of LSC typically fail. Rather, greater safety/efficacy is associated with direct surgical resection with/without fusion. Methods: Treatment of LSC with percutaneous techniques, including cyst aspiration/perforation, injection (i.e., with/without steroids, saline/other), dilatation, and/or disruption/bursting, classically fail. This is because LSCs' tough, thickened, and adherent fibrous capsules cause extensive thecal sac/nerve root compression, and contain minimal central "fluid" (i.e., "crank-case" and non-aspirable). Multiple percutaneous attempts at decompression, therefore, typically cause several needle puncture sites risking dural tears (DT)/cerebrospinal fluid (CSF) leaks, direct root injuries, failure to decompress the thecal sac/nerve roots, infections, hematomas, and over the longer-term, adhesive arachnoiditis. Results: Alternatively, many studies document the success of direct or even partial resection of LSC (i.e., partial removal with marked cyst/dural adhesions with shrinking down the remnant of capsular tissue). Surgical decompressions of LSC, ranging from focal laminotomies to laminectomies, may or may not warrant additional fusions. Conclusions: Symptomatic LSC are best managed with direct or even partial operative resection/decompression with/without fusion. The use of varying percutaneous techniques classically fails, and increases multiple perioperative risks.

9.
Cureus ; 15(3): e36344, 2023 Mar.
Article in English | MEDLINE | ID: mdl-37082494

ABSTRACT

Adnexal torsion due to hyperstimulation is one of the well-recognized serious complications of assisted reproductive techniques like in vitro fertilization (IVF). We report a case of a 35-year-old primigravida who presented to the emergency department with complaints of acute severe left iliac fossa pain and nausea. Further history revealed that the patient had previously undergone one cycle of ovulation induction and was diagnosed with ovarian hyperstimulation syndrome (OHSS). After prompt management, she reportedly underwent a cycle of IVF successfully. Her gestational age was five weeks and one day on presentation. A transabdominal ultrasound revealed bilateral enlarged ovaries with adequate blood supply and a single intrauterine gestational sac with a yolk sac. The patient was admitted as a case of recurrent OHSS for conservative management. Despite the initial improvement of symptoms with parenteral analgesia, an emergency laparoscopic surgery was done later due to worsening symptoms. Intraoperative findings were consistent with the suspected diagnosis of adnexal torsion which was managed accordingly. Postoperatively, the patient recovered without complications and was discharged two days later with a plan for outpatient follow-up.

10.
Cureus ; 15(10): e47966, 2023 Oct.
Article in English | MEDLINE | ID: mdl-38034202

ABSTRACT

Renal cysts are prevalent conditions and are often diagnosed incidentally. The infection of renal cysts is an uncommon presentation. It is even more rare in solitary simple cysts than in autosomal dominant polycystic kidney disease (ADPKD). Patients with infected renal cysts can have variable presenting symptoms; however, almost universally, they have flank pain. Here, we report a case of a solitary renal cyst infection in the absence of flank pain, a relatively rare condition. A 60-year-old male patient presented to our emergency department (ED) for ongoing periumbilical/lower abdominal pain, chills, and high-grade fever. He was initially seen in urgent care and thought to have a urinary tract infection (UTI). He was discharged on trimethoprim-sulfamethoxazole (TMP-SMX). He was hemodynamically stable in the ED and did not have flank pain. Urine culture showed Escherichia coli. Computed tomography (CT) showed changes concerning for possible early pyelonephritis of the right kidney area and an enlarged right upper pole renal cyst compared to previous imaging. The urology team was consulted, and the enlarging cyst was considered secondary to hemorrhage. The patient continued to have high-grade fevers and worsening abdominal pain during his stay despite being on culture-directed intravenous antibiotics. Consequently, the cyst was aspirated, and cultures grew E. coli with a similar antimicrobial susceptibility pattern as the one found in the urine. After the procedure, the fever and abdominal pain significantly improved. This case report describes a patient with an infected solitary renal cyst with a unique presentation. Imaging modalities can be misleading and delay the diagnosis. Appropriate source control via cyst aspiration and/or drain insertion is crucial for successful treatment.

11.
Cureus ; 15(4): e37692, 2023 Apr.
Article in English | MEDLINE | ID: mdl-37206534

ABSTRACT

Intra-articular ganglion cysts of the knee are a rare occurrence in pediatric patients, particularly involving the anterior cruciate ligament (ACL). Only a handful of case reports have been documented in the medical literature, highlighting the rarity of this condition. Patients with intra-articular cysts often experience knee discomfort and mechanical symptoms like locking of the knee. We present the case of a 13-year-old boy who had a unilateral intra-articular ganglion cyst of the ACL in his left knee. To diagnose and treat the cyst, we conducted radiographs and MRIs, and arthroscopic drainage was performed, resulting in a successful cyst decompression. Our case report provides an overview of the pathogenesis, diagnostic methods, treatment options, and complications of treatment for intra-articular cysts of the ACL. It highlights the rarity of this condition in pediatric patients and underscores the importance of prompt diagnosis and appropriate management.

12.
Front Surg ; 9: 901674, 2022.
Article in English | MEDLINE | ID: mdl-35651693

ABSTRACT

Background: Therapy for large or deep cystic brain metastases is a troublesome procedure in clinical departments. Stereotactic cyst aspiration, combined with Gamma Knife radiosurgery, can be an effective treatment for cystic brain metastases. However, there is still a possibility that a reaccumulation of cystic fluid may lead to poor efficacy or even reoperation. Case presentation: We present a case of a 67-year-old man who was diagnosed with lung cancer brain metastasis. The intracranial lesion seen on imaging appeared to be cystic and located deep inside the brain with associated limb dysfunction. The patient did not respond well to chemotherapy and underwent cyst aspiration with Ommaya reservoir implantation under neuronavigation. Repeated cystic fluid reaccumulation and exacerbation of symptoms occurred during treatment. We performed repeated aspiration via the Ommaya reservoir to control the symptoms and combined it with radiotherapy. During the follow-up period of 14 months, the intracranial tumor was effectively and satisfactorily controlled. Conclusions: We highlight that Ommaya reservoir implantation during stereotactic cyst aspiration is necessary to prevent fluid reaccumulation, thereby avoiding the need for a second surgical procedure.

13.
Proc (Bayl Univ Med Cent) ; 34(1): 189-190, 2020 Aug 27.
Article in English | MEDLINE | ID: mdl-33456197

ABSTRACT

A 27-year-old woman underwent aspiration and bioresorbable cement injection of a simple bone cyst. During injection, cement was seen on fluoroscopy extravasating into the posterior vein of the ankle. The procedure was immediately stopped, and the patient remained hemodynamically stable. Vascular leakage of bone cement during injection of a bone cyst is rare but can have catastrophic consequences.

14.
Acta Radiol Open ; 8(6): 2058460119859353, 2019 Jun.
Article in English | MEDLINE | ID: mdl-31285852

ABSTRACT

Improvement in breast cancer screening technology has increased the detection of architectural distortion, which can often indicate underlying malignancy; however, there are also many benign causes of architectural distortion. We present a case of architectural distortion caused by cyst aspiration, representing a novel, benign cause.

15.
Pan Afr Med J ; 33: 98, 2019.
Article in French | MEDLINE | ID: mdl-31489076

ABSTRACT

Tarlov cyst or perineural cyst is a local dilation of the subarachnoid space formed within the nerve root and filled with cerebrospinal fluid. There is no consensus on the best treatment of syntomatic sacral perinervous cysts. Many methods have been used to treat these symptomatic lesions, with variable results. We report a case series including 20 patients undergoing surgery for sacral Tarlov cyst. Our results were satisfactory; 80% of patients improved without neurological worsening in the post-operative period. Our surgical technique (sacral laminectomy+cyst puncture+establishment of dural sheat) described for the first time in this study seems to have been effective in the 20 cases reported in our study.


Subject(s)
Laminectomy/methods , Sacrum/surgery , Tarlov Cysts/surgery , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Sacrum/pathology , Subarachnoid Space/pathology , Tarlov Cysts/diagnosis
16.
Oncol Lett ; 12(1): 343-347, 2016 Jul.
Article in English | MEDLINE | ID: mdl-27347148

ABSTRACT

In the present study, the efficacy and clinical outcomes of stereotactic aspiration combined with the Gamma Knife radiosurgery (GKRS) method were evaluated retrospectively for patients with large cystic brain metastases. This combined method aims to decrease the tumor weight (volume) and increase the possible radiation dose. The present study involved 48 patients who were diagnosed with cystic metastatic brain tumors between January 2008 and December 2012 in the Department of Neurosurgery of Nanfang Hospital Southern Medical University (Guangzhou, China). Every patient underwent Leksell stereotactic frame, 1.5T magnetic resonance imaging (MRI)-guided stereotactic cyst aspiration and Leksell GKRS. Subsequent to the therapy, MRI was performed every 3 months. The results indicated that 48 cases were followed up for 24-72 months, with a mean follow-up duration of 36.2 months. Following treatment, 44 patients (91.7%) exhibited tumor control and 4 patients (8.3%) experienced progression of the local tumor. During this period, 35 patients (72.9%) succumbed, but only 2 (4.2%) of these succumbed to the brain metastases. The total local control rate was 91.7% and the median overall survival time of all patients was 19.5 months. The 1-year overall survival rate was 70.8% and the 2-year overall survival rate was 26.2%. In conclusion, these results indicated that the method of stereotactic cyst aspiration combined with GKRS was safe and effective for patients with large cystic brain metastases. This method is effective for patients whose condition is too weak for general anesthesia and in whom the tumors are positioned at eloquent areas. This method enables patients to avoid a craniotomy, and provides a good tumor control rate, survival time and quality of life.

17.
Sports Health ; 7(5): 409-14, 2015.
Article in English | MEDLINE | ID: mdl-26502415

ABSTRACT

BACKGROUND: The purpose of this study was to determine the efficacy of ultrasound-guided aspiration, fenestration, and injection as a treatment in patients with symptomatic popliteal cysts. HYPOTHESIS: Ultrasound-guided aspiration, fenestration, and injection (UGAFI) is an effective and safe treatment option for symptomatic popliteal cysts. STUDY DESIGN: Retrospective cohort study. LEVEL OF EVIDENCE: Level 3. METHODS: Patients who received a UGAFI of popliteal cysts from 2008 to 2011 were identified. Preaspiration (PA) and follow-up Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores, cyst recurrence, complications, cyst complexity, and size were obtained and compared for statistical significance. UGAFI involved aspiration of fluid through a spinal needle, fenestration of the cyst walls and septations, and injection of 1 mL (40 mg) triamcinolone (Kenalog) and 2 mL 0.5% bupivacaine (Sensorcaine) into the decompressed remnant. RESULTS: The mean PA WOMAC score (48.55) improved significantly at final follow-up (FFU) to 17.15 (P < 0.0001) for 47 patients. Within the WOMAC subcategories, there was also a significant difference in pain (PA, 10.68; FFU, 3.94; P < 0.0001), stiffness (PA, 4.51; FFU, 1.77; P < 0.0001), and physical function (PA, 31.34; FFU, 12.17; P < 0.0001). There were 6 reaspirations for recurrence (12.7%), and 1 patient underwent unicompartmental knee arthroplasty. There were no infections or other complications. CONCLUSION: Significant clinical improvement in patients with symptomatic popliteal cysts can be achieved via UGAFI as the sole treatment. CLINICAL RELEVANCE: UGAFI is a safe and effective option as the sole treatment modality for symptomatic popliteal cysts.


Subject(s)
Popliteal Cyst/surgery , Suction/methods , Adult , Aged , Aged, 80 and over , Anesthetics, Local/administration & dosage , Arthralgia/etiology , Arthralgia/prevention & control , Bupivacaine/administration & dosage , Female , Follow-Up Studies , Glucocorticoids/administration & dosage , Humans , Injections , Male , Middle Aged , Osteoarthritis, Knee/complications , Popliteal Cyst/complications , Popliteal Cyst/diagnostic imaging , Recurrence , Retrospective Studies , Suction/adverse effects , Treatment Outcome , Triamcinolone/administration & dosage , Ultrasonography
18.
Korean J Urol ; 55(7): 493-5, 2014 Jul.
Article in English | MEDLINE | ID: mdl-25045450

ABSTRACT

Hydatid disease is endemic in parts of India, yet genitourinary involvement is rare. Laparoscopic management of such cases is uncommonly reported. We present a case of an adrenal hydatid and its management by laparoscopic aspiration, instillation of scolicidal solution, and partial excision of the cyst.


Subject(s)
Adrenal Gland Diseases/therapy , Echinococcosis/therapy , Laparoscopy/methods , Adrenal Gland Diseases/diagnostic imaging , Adrenal Gland Diseases/pathology , Albendazole/therapeutic use , Anticestodal Agents/therapeutic use , Combined Modality Therapy , Echinococcosis/diagnostic imaging , Echinococcosis/pathology , Female , Humans , Middle Aged , Tomography, X-Ray Computed
19.
J Korean Neurosurg Soc ; 46(4): 360-4, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19893727

ABSTRACT

OBJECTIVE: Several treatment options have proven effective for metastatic brain tumors, including surgery and stereotactic radiosurgery. Tumors with cystic components, however, are difficult to treat using a single method. We retrospectively assessed the outcome and efficacy of gamma knife radiosurgery (GKRS) for cystic brain metastases after stereotactic aspiration of cystic components to decrease the tumor volume. METHODS: The study population consisted of 24 patients (13 males, 11 females; mean age, 58.3 years) with cystic metastatic brain tumors treated from January 2002 to August 2008. Non-small cell lung cancer was the most common primary origin. After Leksell stereotactic frame was positioned on each patient, magnetic resonance images (MRI)-guided stereotactic cyst aspiration and GKRS were performed (mean prescription dose : 20.2 Gy). After treatment, patients were evaluated by MRI every 3 or 4 months. RESULTS: After treatment, 13 patients (54.2%) demonstrated tumor control, 5 patients (20.8%) showed local tumor progression, and 6 patients (25.0%) showed remote progression. Mean follow-up duration was 13.1 months. During this period, 10 patients (41.7%) died, but only 1 patient (4.2%) died from brain metastases. The overall median survival after these procedures was 17.8 months. CONCLUSION: These results support the usefulness of GKRS after stereotactic cyst aspiration in patients with large cystic brain metastases. This method is especially effective for the patients whose general condition is very poor for general anesthesia and those with metastatic brain tumors located in eloquent areas.

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