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1.
Nihon Koshu Eisei Zasshi ; 68(1): 3-11, 2021 Jan 30.
Article in Japanese | MEDLINE | ID: mdl-33087640

ABSTRACT

Objectives The main purpose of rehabilitation is to improve the activities of daily living (ADL). Although convalescent wards are required to provide intensive rehabilitation to patients to improve their ADL, they have not been verified sufficiently. With a focus on the rehabilitation time, this study investigated the association of the amount of rehabilitation with ADL using a complete enumeration survey of a hospital bed function report system.Methods This retrospective cohort study focusing on convalescent wards nationwide was conducted using the panel data from hospital bed function reports between 2014 and 2017. We used a fixed effects regression analysis with the improvement rate of ADL as the outcome measure and the number of rehabilitation units as the exposure variable.Results The study sample included 2,003 wards, which were identified as having convalescent care functions from the report in 2014; a total of 437 wards (317 hospitals) were analyzed. The mean annual improvement rates of ADL were 0.601, 0.613, and 0.627 points in 2014, 2015, and 2017, respectively. The mean annual numbers of rehabilitation units provided were 6.302, 6.477, and 6.642 units in 2014, 2015, and 2017, respectively. The panel data analysis showed that the improvement rate of ADL was associated with an increase in the number of rehabilitation units (coefficient for an increase of one unit: 0.015, P=0.015).Conclusion In the study of ward units using a national-level survey, a longer rehabilitation time was significantly associated with improvements in ADL.


Subject(s)
Activities of Daily Living , Beds , Cerebrovascular Disorders/rehabilitation , Hospitals, Convalescent/statistics & numerical data , Rehabilitation Centers/statistics & numerical data , Cerebrovascular Disorders/physiopathology , Female , Humans , Male , Regression Analysis , Retrospective Studies , Time Factors
2.
J Head Trauma Rehabil ; 35(1): E51-E59, 2020.
Article in English | MEDLINE | ID: mdl-31246883

ABSTRACT

OBJECTIVE: Determine incidence and predictors of comorbid cerebrovascular injuries in patients with moderate to severe traumatic brain injury (TBI) and whether it influences rehabilitation outcomes. SETTING: Inpatient Rehabilitation Facility (IRF) brain injury unit participating in NIDILRR TBI Model Systems (TBIMS). PARTICIPANTS: A total of 663 patients with moderate to severe TBI. DESIGN: Observational study with prospective and retrospective data collection. MAIN MEASURES: New traumatic cerebral artery injury (TCAI) lesions of head/neck and new cerebral infarcts (CIs) abstracted from neuroimaging reports and clinical notes. RESULTS: The incidence of comorbid CI was 8%, among whom 19% also had TCAI identified. The incidence of TCAI increased over time from 2% before 2008 to 10% after, probably from greater screening. Both CI and TCAI were associated with longer acute care stay. Cerebral infarct was also associated with longer posttraumatic amnesia and lower rate of functional gains. CONCLUSIONS: Using in-depth abstraction of imaging findings, the incidence of traumatic head/neck artery injuries, and CIs in patients with moderate to severe TBI were both higher than a recent TBIMS-wide study utilizing ICD coding. Cerebral infarct was associated with longer posttraumatic amnesia duration and slower functional gains. Further research is recommended on the outcome implications of concomitant cerebrovascular injury in patients with TBI.


Subject(s)
Brain Injuries, Traumatic/complications , Brain Injuries, Traumatic/rehabilitation , Cerebrovascular Disorders/epidemiology , Cerebrovascular Disorders/rehabilitation , Rehabilitation Centers , Adult , Brain Injuries, Traumatic/diagnosis , Cerebrovascular Disorders/diagnosis , Cohort Studies , Female , Hospitalization , Humans , Incidence , Male , Middle Aged , Time Factors
3.
Neurol Sci ; 38(1): 181-184, 2017 Jan.
Article in English | MEDLINE | ID: mdl-27696274

ABSTRACT

Establish the best time to start rehabilitation by means of scientific evidence. Observational study in patients with a diagnosis of Severe Brain Injury who received intensive inpatient rehabilitation after acute care. 1470 subjects enrolled: 651 with Traumatic Brain Injury (TBI) and 819 with Non-TBI. Male gender was prevalent in the population study, but sex distribution was not different among groups, with a prevalence of male gender in both populations. This project involved 29 rehabilitation facilities for Severe ABI. The registry was an electronic database, remained active only during the period of data collection. The patients were divided into three different categories according to the time interval from brain injury to inpatient rehabilitation admission and demographic and clinical data were collected. Etiology, time interval from injury to inpatient rehabilitation, disability severity, the presence of tracheostomy at admission to the rehabilitation facility, rehabilitation length of stay and transfer back to acute care wards because of medical, surgical or neurosurgical complications. The interval from brain injury to rehabilitation facilities admission increases along with age, brain injury severity according to DRS scores, the presence of a tracheal tube and the percentage of transfers back to acute care wards from rehabilitation facilities, because of medical, surgical or neurosurgical complications. The better recovery and more positive outcomes, reported as resulting from early rehabilitation, may be due more to less severity of brain injury and fewer complications in the acute and post-acute phase than to when the rehabilitation starts.


Subject(s)
Brain Injuries, Traumatic/rehabilitation , Cerebrovascular Disorders/rehabilitation , Hypoxia, Brain/rehabilitation , Neurological Rehabilitation , Adult , Aged , Female , Humans , Inpatients , Length of Stay , Male , Middle Aged , Recovery of Function , Rehabilitation Centers , Time Factors , Treatment Outcome , Young Adult
4.
Neuropsychol Rehabil ; 27(1): 116-132, 2017 Jan.
Article in English | MEDLINE | ID: mdl-26282626

ABSTRACT

The objective of this study was to investigate changes in self-awareness impairments in outpatients with acquired brain injury (ABI) and the effects these changes have on rehabilitation. Participants were 78 patients with ABI (8.3 years post-injury) who followed an intensive outpatient neuropsychological rehabilitation programme. This longitudinal study comprised pre (T1) and post (T2) measurements and a one-year follow-up (T3). Thirty-eight patients completed the study. The main outcome domains were self-awareness, depressive symptoms, psychological and physical dysfunction, and health-related quality of life (HRQoL). Patients were divided into three awareness groups: underestimation, accurate estimation, and overestimation of competencies. Most patients who underestimated their competencies at the start of treatment accurately estimated their competencies directly after treatment (9 out of 11 patients). These patients also exhibited the largest treatment effects regarding depressive symptoms, psychological and physical dysfunction, and HRQoL. Most patients with impaired self-awareness (i.e., overestimation of competencies) at the start of treatment continued to overestimate their competencies after treatment (10 out of 14 patients). These patients exhibited a significant decrease in depressive symptoms but no other treatment effects. The results indicate that changes in outcome are related to changes in awareness, which underline the importance of taking into account different awareness groups with respect to treatment effects.


Subject(s)
Awareness , Brain Injuries/rehabilitation , Depression/psychology , Health Status , Neurological Rehabilitation/methods , Quality of Life/psychology , Self Concept , Activities of Daily Living , Adult , Brain Injuries/psychology , Brain Injuries, Traumatic , Brain Neoplasms/psychology , Brain Neoplasms/rehabilitation , Cerebrovascular Disorders/psychology , Cerebrovascular Disorders/rehabilitation , Cohort Studies , Female , Humans , Hypoxia, Brain/psychology , Hypoxia, Brain/rehabilitation , Longitudinal Studies , Male , Middle Aged , Self-Assessment , Treatment Outcome
5.
J Stroke Cerebrovasc Dis ; 25(1): 57-62, 2016 Jan.
Article in English | MEDLINE | ID: mdl-26409716

ABSTRACT

BACKGROUND: Malnutrition affects the activities of daily living (ADLs) in convalescent patients with cerebrovascular disorders. We investigated the relationship between nutritional improvement, energy intake at admission, and recovery of ADLs. METHODS: We evaluated 67 patients with cerebrovascular disorders admitted to our rehabilitation hospital between April 2013 and April 2015. These patients received interventions from the rehabilitation nutritional support team according to the following criteria: weight loss of 2 kg or more and body mass index of 19 kg/m(2) or lower. Exclusion criteria included a body mass index of 25 kg/m(2) or higher, duration of intervention of less than 14 days, or transfer to an acute care hospital because of clinical deterioration. We assessed nutritional status using the Geriatric Nutritional Risk Index (GNRI) and ADL using the Functional Independence Measure (FIM) score, FIM gain, and FIM efficiency. RESULTS: The mean age of the patients was 78.7 ± 8.0 years. The numbers of patients in each category of cerebrovascular disorder were 39 with cerebral infarction, 16 with intracerebral hemorrhage, 8 with subarachnoid hemorrhage, and 4 others. Compared with the counterpart group, the group with an improvement in GNRI had a greater gain in FIM (median 17 and 20, respectively; P = .036) and a higher FIM efficiency (.14 and .22, respectively; P = .020). Multivariate stepwise regression analysis showed that an improvement in GNRI, increasing energy intake at admission, and intracerebral hemorrhage were associated independently with greater FIM efficiency. CONCLUSIONS: This study suggested that nutritional improvement and energy intake at admission are associated with recovery of ADL after cerebrovascular disorders.


Subject(s)
Cerebrovascular Disorders/rehabilitation , Energy Intake , Malnutrition/prevention & control , Nutritional Status , Activities of Daily Living , Aged , Aged, 80 and over , Body Mass Index , Cerebrovascular Disorders/complications , Cerebrovascular Disorders/physiopathology , Cross-Sectional Studies , Female , Humans , Japan/epidemiology , Male , Malnutrition/complications , Nutritional Support , Recovery of Function , Rehabilitation Centers , Retrospective Studies , Thinness/epidemiology , Weight Loss
6.
BMC Neurol ; 15: 239, 2015 Nov 21.
Article in English | MEDLINE | ID: mdl-26589284

ABSTRACT

BACKGROUND: So far, the role of clinical neurophysiology in the prediction of outcome from neurological and neurosurgical early rehabilitation is unclear. METHODS: Clinical and neurophysiological data of a large sample of 803 early rehabilitation cases of the BDH-Clinic Hessisch Oldendorf in Northern Germany have been carefully reviewed. Most patients (43.5%) were transferred to rehabilitation after stroke, mean age was 66.6 (15.5) years. Median somatosensory (SEP), auditory (AEP) and visual evoked potentials (VEP) along with EEG recordings took place within the first two weeks after admission. Length of stay (LOS) in early rehabilitation was 38.3 (37.2) days. RESULTS: Absence of SEP on one or both sides was associated with poor outcome, χ2 = 12.98 (p = 0.005); only 12.5% had a good outcome (defined as Barthel index, BI ≥50) when SEP were missing on both sides. In AEP, significantly longer bilateral latencies III were observed in the poor outcome group (p < 0.05). Flash VEP showed that patients in the poor outcome group had a significantly longer latency III on both sides (p < 0.05). The longer latency III, the smaller BI changes (BI discharge minus admission) were observed (latency III right r = -0.145, p < 0.01; left r = -0.206, p < 0.001). While about half of the patients with alpha EEG activity belonged to the good outcome group (80/159, 50.3%), only 39/125 (31.2%) with theta and 5/41 (12.2%) with delta rhythm had a favourable outcome, χ2 = 24.2, p < 0.001. CONCLUSIONS: Results from this study suggest that loss of median SEP, prolongation of wave III in AEP and flash-VEP as well as theta or delta rhythms in EEG are associated with poor outcome from neurological early rehabilitation. Further studies on this topic are strongly encouraged.


Subject(s)
Cerebrovascular Disorders/rehabilitation , Patient Outcome Assessment , Recovery of Function/physiology , Aged , Cerebrovascular Disorders/physiopathology , Electroencephalography , Evoked Potentials, Auditory/physiology , Evoked Potentials, Somatosensory/physiology , Evoked Potentials, Visual/physiology , Female , Humans , Male , Middle Aged , Retrospective Studies
7.
J Stroke Cerebrovasc Dis ; 24(4): 815-22, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25687939

ABSTRACT

BACKGROUND: Prediction of upper limb function recovery in the acute phase of cerebrovascular disease can help clarify goal setting in rehabilitation and subsequently shorten hospital stay. The present study aimed to develop regression equations that can be used to predict the Manual Function Test (MFT) score 3 weeks after onset and to determine the optimal cutoff MFT score for the identification of "Functional Hand." METHODS: In all, 190 patients with cerebrovascular disease were included in this study. The baseline survey performed within 1 week after onset assessed sociodemographic profiles, medical profiles, and acute symptoms. MFT was performed to determine the cutoff score to indicate Functional Hand. We used stepwise multiple regression analysis to establish the prediction equations with the best fit for the MFT score 3 weeks after onset. In addition, the sensitivity and specificity of the MFT as an indicator of Functional Hand with cutoff values were determined. RESULTS: The multiple regression analysis showed that the following factors had a significant influence on the MFT: Brunnstrom recovery stage, cognitive function, range of motion, age, and sensation. The area under the curve was .93 for the MFT score as an indicator of Functional Hand. The cutoff MFT score to identify Functional Hand was 22/21 points, with a sensitivity and specificity of 91.1% and 82.1%, respectively. CONCLUSIONS: Our findings helped develop regression equations that can be used to predict the MFT score 3 weeks after onset of cerebrovascular disease by evaluating factors reportedly associated with upper limb function recovery.


Subject(s)
Cerebrovascular Disorders/physiopathology , Cerebrovascular Disorders/rehabilitation , Hand/physiopathology , Recovery of Function/physiology , Treatment Outcome , Upper Extremity/physiopathology , Aged , Aged, 80 and over , Cerebrovascular Disorders/diagnosis , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Psychomotor Performance , ROC Curve , Regression Analysis
8.
J Stroke Cerebrovasc Dis ; 24(7): 1527-31, 2015 Jul.
Article in English | MEDLINE | ID: mdl-25881771

ABSTRACT

BACKGROUND: Outcome studies in intensive care unit -dependent, tracheotomized, and mechanical ventilated patients with cerebrovascular disease (CVD) are scarce. METHODS: In a retrospective approach, we analyzed the outcome of 143 patients with ischemic stroke (IS), primary intracerebral hemorrhage (PICH), and subarachnoid hemorrhage (SAH). To measure the potential benefit of in-patient rehabilitation, we used the Functional Independence Measure (FIM). In addition, weaning and rehabilitation duration, duration of mechanical ventilation (MV) in the acute care hospital (preweaning), and mortality rates were assessed. RESULTS: Approximately 50% of all patients were transferred home. These patients were fully independent or under nursing support. We found no differences regarding weaning and rehabilitation durations, or FIM scores in between each entity. Log-regression analyses showed that every day on MV generates a 3.2% reduction of the possibility to achieve a beneficial outcome (FIM ≥ 50 points [only moderate assistance necessary]), whereas every day in-patient rehabilitation without MV increases the chance for favorable outcome by 1.9%. Mortality rates were 5% for IS and 10% for PICH and SAH, respectively. CONCLUSIONS: This study shows that even severely affected, tracheotomized patients with CVD benefit from early in-patient rehabilitation, irrespective of the etiology of vascular brain injury. Mortality rates of early rehabilitation in CVD are low. Until no validated outcome predictors are available, all efforts should be undertaken to enable in-patient rehabilitation, even in severe cases of CVD to improve outcome and to prevent accommodation in long-time-care facilities.


Subject(s)
Cerebrovascular Disorders/mortality , Cerebrovascular Disorders/rehabilitation , Critical Care , Intensive Care Units , Respiration, Artificial , Tracheostomy , Activities of Daily Living , Adult , Aged , Aged, 80 and over , Brain Ischemia/therapy , Cerebral Hemorrhage/therapy , Cerebrovascular Disorders/diagnosis , Cerebrovascular Disorders/physiopathology , Disability Evaluation , Female , Home Nursing , Hospital Mortality , Humans , Male , Middle Aged , Patient Discharge , Patient Transfer , Recovery of Function , Retrospective Studies , Risk Factors , Severity of Illness Index , Stroke/therapy , Subarachnoid Hemorrhage/therapy , Time Factors , Treatment Outcome , Ventilator Weaning
9.
BMC Neurol ; 14: 34, 2014 Feb 21.
Article in English | MEDLINE | ID: mdl-24555811

ABSTRACT

BACKGROUND: Colonization with MRSA is believed to have deteriorating effects on neurological rehabilitation patients because MRSA carriers need to be isolated. METHODS: Medical records of neurological early rehabilitation patients (most of them after stroke) admitted to a large rehabilitation facility in Northern Germany in 2010 have been carefully reviewed with respect to MRSA status, outcome variables (functional independence), morbidity, and length of stay (LOS). RESULTS: 74/569 (13.0%) patients were MRSA positive on admission. MRSA carriers had a significantly longer LOS in early neurological rehabilitation (63.7 (37.1) vs. 25.8 (24.5) days, p < 0.001), worse functional status on admission (Barthel index (BI) 13.6 (9.9) vs. 25.6 (24.1), p < 0.001), worse Glasgow Coma Scale (9.5 (3.2) vs. 12.0 (3.3), p < 0.001), more co-diagnoses (20.5 (5.1) vs. 13.3 (5.5), p < 0.001), and higher Patient Clinical Complexity Levels (PCCL). The outcome was significantly worse among MRSA positive patients (BI 25.5 (21.2) vs. 47.4 (31.0), p < 0.001; Early Rehabilitation Index -47.3 (51.4) vs. -26.0 (35.4), p < 0.001). Isolated patients had slightly less therapy per day (131.6 (16.6) vs. 140.2 (18.7) min/day, p < 0.001), but the overall sum of therapy was significantly larger in the MRSA positive group due to longer LOS. CONCLUSIONS: Functional recovery of MRSA carriers in early neurological rehabilitation is worse than in MRSA negative patients. Poorer outcome is not resulting from isolation (less therapy) but from functional status and higher morbidity on admission.


Subject(s)
Cerebrovascular Disorders/microbiology , Cerebrovascular Disorders/rehabilitation , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Nervous System Diseases/microbiology , Nervous System Diseases/rehabilitation , Recovery of Function/physiology , Adolescent , Adult , Aged , Aged, 80 and over , Cerebrovascular Disorders/diagnosis , Female , Humans , Male , Middle Aged , Nervous System Diseases/diagnosis , Rehabilitation Centers/trends , Treatment Outcome , Young Adult
10.
Klin Med (Mosk) ; 92(5): 54-8, 2014.
Article in Russian | MEDLINE | ID: mdl-25782308

ABSTRACT

High prevalence of cardiovascular and cerebrovascular diseases dictates the necessity of enhancing the efficacy of preventive and rehabilitative programs, elaboration and implementation of innovative medical technologies. Sleep disturbances and especially associated respiratory disorders are important risk factors of arterial hypertension, cardiac insufficiency, abnormal heart rhythms, cerebrovascular pathology, insulin resistance, and type 2 diabetes mellitus. Introduction of the methods for diagnostics and correction of sleep disturbances into rehabilitative programs improves immediate and long-term results of the treatment.


Subject(s)
Cardiac Rehabilitation , Cerebrovascular Disorders/rehabilitation , Continuous Positive Airway Pressure/methods , Respiratory Insufficiency , Sleep Wake Disorders , Aged , Breath Tests/methods , Cardiovascular Diseases/complications , Cerebrovascular Disorders/complications , Female , Heart Function Tests/methods , Humans , Male , Middle Aged , Polysomnography/methods , Respiration , Respiratory Insufficiency/diagnosis , Respiratory Insufficiency/etiology , Respiratory Insufficiency/physiopathology , Respiratory Insufficiency/prevention & control , Retrospective Studies , Russia , Sleep Wake Disorders/diagnosis , Sleep Wake Disorders/etiology , Sleep Wake Disorders/physiopathology , Sleep Wake Disorders/prevention & control , Treatment Outcome
11.
Arch Phys Med Rehabil ; 94(12): 2373-2380, 2013 Dec.
Article in English | MEDLINE | ID: mdl-23850613

ABSTRACT

OBJECTIVE: To examine characteristics associated with functional recovery in older patients undergoing postacute rehabilitation. DESIGN: Observational study. SETTING: Postacute rehabilitation facility. PARTICIPANTS: Patients (N=2754) aged ≥65 years admitted over a 4-year period. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURE: Functional status was assessed at admission and again at discharge. Functional recovery was defined as achieving at least 30% improvement on the Barthel Index score from admission compared with the maximum possible room for improvement. RESULTS: Patients who achieved functional recovery (70.3%) were younger and were more likely to be women, live alone, and be without any formal home care before admission, and they had fewer chronic diseases (all P<.01). They also had better cognitive status and a higher Barthel Index score both at admission (mean ± SD, 63.3±18.0 vs 59.6±24.7) and at discharge (mean ± SD, 86.8±10.4 vs 62.2±22.9) (all P<.001). In multivariate analysis, patients <75 years of age (adjusted odds ratio [OR]=1.51; 95% confidence interval [CI], 1.16-1.98; P=.003), women (adjusted OR=1.24; 95% CI, 1.01-1.52; P=.045), patients living alone (adjusted OR=1.61; 95% CI, 1.31-1.98; P<.001), and patients without in-home help prior to admission (adjusted OR=1.39; 95% CI, 1.15-1.69; P=.001) remained at increased odds of functional recovery. In addition, compared with those with moderate-to-severe cognitive impairment (Mini-Mental State Examination score <18), patients with mild-to-moderate impairment (Mini-Mental State Examination score 19-23) and those cognitively intact also had increased odds of functional recovery (adjusted OR=1.56; 95% CI, 1.13-2.15; P=.007; adjusted OR=2.21; 95% CI, 1.67-2.93; P<.001, respectively). CONCLUSIONS: Apart from sociodemographic characteristics, cognition is the strongest factor that identifies older patients more likely to improve during postacute rehabilitation. Further study needs to determine how to best adapt rehabilitation processes to better meet the specific needs of this population and optimize their outcome.


Subject(s)
Recovery of Function/physiology , Rehabilitation Centers , Age Factors , Aged , Aged, 80 and over , Cardiac Rehabilitation , Cerebrovascular Disorders/rehabilitation , Cognition/physiology , Cognition Disorders/physiopathology , Female , Gastrointestinal Diseases/rehabilitation , Humans , Independent Living , Joint Diseases/rehabilitation , Male , Multivariate Analysis , Neuropsychological Tests , Patient Admission , Respiratory Tract Diseases/rehabilitation , Sex Factors , Wounds and Injuries/rehabilitation
12.
Neurologia ; 28(3): 137-44, 2013 Apr.
Article in English, Spanish | MEDLINE | ID: mdl-22703634

ABSTRACT

INTRODUCTION: Cerebrovascular disease is associated with high morbidity and mortality. In 2008, the Spanish Ministry of Health published its Clinical Practice Guidelines for stroke prevention, but implementation of that document has not yet been assessed. Our study aims to investigate compliance with the Guidelines by analysing control over vascular risk factors, antithrombotic treatment and lipid lowering treatment in patients who had suffered an acute ischaemic stroke and who were under the care of neurologists or internists. METHODS: Cross-sectional study based on data from clinical reports (vascular risk factors, diagnosis and treatment), blood pressure readings and laboratory tests pertaining to 203 patients diagnosed with acute ischaemic stroke and admitted to a medium-to-long stay hospital for rehabilitation and care. RESULTS: The mean patient age was 75 ± 10 years; 56% were women. The most common risk factors were hypertension (68%) and diabetes mellitus (40%). Intravenous fibrinolytic therapy had been administered to 8.9% of the patients. Of the patients with thrombotic cerebral infarction, 91.7% received antiplatelet agents; 59.4% of patients with embolic infarction received anticoagulants. Statins were prescribed to 65% of patients with thrombotic infarction. Laboratory tests upon admission showed that 23% of patients had total cholesterol levels above 175 mg/dl and 26.6% had plasma glucose levels above 126 mg/dl. Of the patient total, 70% received antihypertensive therapy, but 47.5% had blood pressure levels above 130/80 mm Hg. CONCLUSIONS: In our opinion, secondary prevention of acute cerebrovascular disease could be improved, mainly by increasing the percentage of patients treated with antiplatelet or anticoagulant drugs (depending on aetiology), increasing prescription of statins, and improving blood pressure control.


Subject(s)
Brain Ischemia/therapy , Stroke/therapy , Aged , Aged, 80 and over , Brain Ischemia/epidemiology , Brain Ischemia/rehabilitation , Cerebrovascular Disorders/rehabilitation , Cerebrovascular Disorders/therapy , Female , Fibrinolytic Agents/therapeutic use , Guidelines as Topic , Hospitalization , Humans , Male , Risk Factors , Spain/epidemiology , Stroke/epidemiology , Stroke Rehabilitation
13.
Article in Russian | MEDLINE | ID: mdl-24437202

ABSTRACT

The present paper reports the data on rehabilitation of women presenting with combined pathology: dyscirculatory encephalopathy and climacteric syndrome. It is shown that the introduction of ozonotherapy and klimadynon, a herbal medicine possessed of the estrogen-like action, into combined rehabilitative treatment ensures the significant improvement of the parameters of interest, such as climacteric symptoms, short-term memory, lipid profile, endothelial function, cerebral circulation, and quality of life.


Subject(s)
Cerebrovascular Disorders , Menopause , Ozone/administration & dosage , Plant Extracts/administration & dosage , Quality of Life , Cerebrovascular Circulation , Cerebrovascular Disorders/blood , Cerebrovascular Disorders/complications , Cerebrovascular Disorders/physiopathology , Cerebrovascular Disorders/rehabilitation , Endothelium, Vascular/metabolism , Endothelium, Vascular/physiopathology , Humans , Lipids/blood , Male , Memory, Short-Term , Middle Aged , Phytotherapy/methods , Syndrome
14.
Nervenarzt ; 83(6): 741-50, 2012 Jun.
Article in German | MEDLINE | ID: mdl-22669125

ABSTRACT

OBJECTIVE: This study characterized artificially ventilated patients in a neurological intensive care unit (NICU) between 2006-2008 in a purely neurological clinic and a so-called stand-alone situation. In addition the long-term prognoses as well as the quality of life of surviving patients were investigated. METHODS: All ventilated patients from October 2006 to December 2008 were enrolled in this descriptive, retrospective study. The duration of stay in intensive care was analyzed and the current quality of life was prospectively assessed based on the patient records. Final diagnoses, duration of intensive care unit and ventilation as well as the highest score in SAPS II (simplified acute physiology score) and complications during hospitalization were determined. The patients were divided into groups based on the diagnoses as vascular, inflammatory, neurodegenerative, hereditary, epileptogenic and others. Additionally patients were contacted and asked to respond by completing questionnaires on the Barthel index (BI) and the modified Rankin scale (mRS). RESULTS: During the study period a total of 512 patients were treated in the NICU of whom 201 required artificial respiration. Cerebrovascular diseases were the main reason for therapy in the NICU in 96 out of 201 cases (47.8%), followed by inflammatory diseases in 46 (22.8%) and epileptogenic diseases in 26 patients (13%). The median duration of artificial respiration was 9 days with a mean treatment duration of 16 days (range 1-57 days). Of the patients 31 (15.4%) died in the NICU and an additional 32 patients (18.8%) died within a median of 2 months after discharge. Outcome data were available from 67 out of 170 sent questionnaires and rehabilitation reports of 86 patients, which enabled the outcome of 121 surviving patients to be analyzed (71.2%). Of these 42.2% showed no or mild impairment in everyday life. However, the remaining 38% had severe impairments according to the BI. The evaluation of the mRS showed that 49.6% of the patients still had severe symptoms. CONCLUSIONS: More than one third of the patients treated in the NICU required artificial ventilation with an emphasis on cerebrovascular diseases, which illustrates the overlap between stroke unit and NICU care. Despite a lengthy duration of ventilation and a long stay in the intensive care unit more than one third of surviving patients showed no or only mild impairment. However, an additional third suffered from severe disability up to nursing care dependency. The study data differ little from the few publications in this field despite the stand alone situation of the NICU. The case mix index per day averaged around 0.3 and underlines the economic importance with respect to other forms of neurological treatment.


Subject(s)
Cerebrovascular Disorders/mortality , Cerebrovascular Disorders/rehabilitation , Intensive Care Units/statistics & numerical data , Neurology/statistics & numerical data , Quality of Life , Respiration, Artificial/mortality , Adult , Aged , Aged, 80 and over , Female , Germany/epidemiology , Humans , Male , Middle Aged , Prevalence , Retrospective Studies , Risk Assessment , Survival Analysis , Survival Rate , Treatment Outcome
16.
Lik Sprava ; (7): 74-5, 2012.
Article in Sr | MEDLINE | ID: mdl-23350118

ABSTRACT

Reducing treatment and rehabilitation of patients with cerebrovascular disease (TSVB) for many years has been one of the priorities of the national health care, which is largely due to a significant increase in the incidence and severity of medical, economic and social consequences of the disease for patients and their relatives, and for society as a whole. The objectives of rehabilitation include: restoring consumer opportunities patient, ie, mobility, self-care and the implementation of simple homework, rehabilitation, ie lost disability skills through the use and development of the skeletal system functionality, preventing the development of pathological processes that lead to temporary or permanent disability, that is, implementation of secondary prevention.


Subject(s)
Cerebrovascular Disorders/prevention & control , Cerebrovascular Disorders/rehabilitation , Activities of Daily Living , Humans , Secondary Prevention
17.
Lik Sprava ; (7): 174-6, 2012.
Article in Ukrainian | MEDLINE | ID: mdl-23350145

ABSTRACT

Chronic cerebrovascular insufficiency is the most common manifestation of chronic diseases of the nervous system. Its main causes are hypertension and atherosclerosis. Diseases debut mainly on 5-6th decade of life. The condition prohreiyentnyy, but the degree of progression can be varied--from slow to galloping. Therefore, when studying the effectiveness of treatment programs, in our opinion, it is important to include the medical complex of different methods of reflexology.


Subject(s)
Acupuncture/methods , Cerebrovascular Disorders/rehabilitation , Low-Level Light Therapy/methods , Acupuncture Points , Cerebrovascular Disorders/diagnosis , Cerebrovascular Disorders/drug therapy , Cerebrovascular Disorders/radiotherapy , Chronic Disease , Combined Modality Therapy , Female , Humans , Male , Middle Aged
18.
Gerontology ; 57(2): 137-43, 2011.
Article in English | MEDLINE | ID: mdl-20453489

ABSTRACT

BACKGROUND: The telomere length and subtelomeric methylated status of peripheral blood leukocytes have been reported to be correlated with many kinds of pathophysiological conditions. However, the correlation between the telomeric parameters and patients' physical ability is not known. OBJECTIVE: This study aims to study how telomeric parameters, including telomere length and the subtelomeric methylation status of peripheral blood leukocytes, are associated with the physical inability of patients with cerebrovascular disease and its improvement by inpatient rehabilitation. METHODS: The physical ability of female patients with cerebrovascular disease admitted in the chronic disease ward of Kyushu University Hospital was assessed using the Barthel index, and the telomeric parameters in their peripheral blood leukocytes were determined by Southern blotting with methylation-sensitive and -insensitive isoschizomers. RESULTS: The patients revealed a significant correlation between Barthel score and the mean telomere length and expression of long telomeres (> 9.4 kb). Improvement of the Barthel index of patients during admission was correlated not to telomere length, but to subtelomeric hypermethylation of long telomeres. CONCLUSIONS: The physical ability of patients was positively correlated with the lengths of their somatic telomeres, and the recovery potential of physical ability was associated with the subtelomeric hypermethylated status stabilizing long telomeric structure.


Subject(s)
Aging/genetics , Cerebrovascular Disorders/genetics , DNA Methylation/genetics , Motor Activity/genetics , Telomere/genetics , Aged , Aged, 80 and over , Asian People/genetics , Cerebrovascular Disorders/ethnology , Cerebrovascular Disorders/rehabilitation , Chronic Disease , Female , Hospitalization/statistics & numerical data , Humans , Leukocytes/physiology , Restriction Mapping
19.
Brain Inj ; 25(4): 416-25, 2011.
Article in English | MEDLINE | ID: mdl-21355675

ABSTRACT

AIM: This study reports the case of a 23-year-old woman (MC) who sustained a severe traumatic brain injury in 2004. After her accident, her driving license was revoked. Despite recovering normal neuropsychological functions in the following years, MC was unable to renew her license, failing four on-road evaluations assessing her fitness to drive. METHOD: In hope of an eventual license renewal, MC went through an in-simulator training programme in the laboratory in 2009. The training programme aimed at improving features of MC's driving behaviour that were identified as being problematic in prior on-road evaluations. To do so, proper driving behaviour was reinforced via driving-specific feedback provided during the training sessions. RESULTS: After 25 sessions in the simulator (over a period of 4 months), MC significantly improved various components of her driving. Notably, compared to early sessions, later ones were associated with a reduced cognitive load, less jerky speed profiles when stopping at intersections and better vehicle control and positioning. A 1-year retention test showed most of these improvements were consistent. CONCLUSIONS: The learning principles underlying well conducted simulator-based education programmes have a strong scientific basis. A simulator training programme like this one represents a promising avenue for driving rehabilitation. It allows individuals without a driving license to practice and improve their skills in a safe and realistic environment.


Subject(s)
Automobile Driving/psychology , Brain Injuries/rehabilitation , Cerebrovascular Disorders/rehabilitation , Attention , Computer Simulation , Disability Evaluation , Female , Humans , Licensure , Neuropsychological Tests , Young Adult
20.
Tidsskr Nor Laegeforen ; 131(8): 819-23, 2011 May 06.
Article in Nor | MEDLINE | ID: mdl-21556085

ABSTRACT

BACKGROUND: Development of stroke units during the last decade has changed management of patients with stroke. The aim of this study is to assess unselected patients admitted to an acute stroke unit with respect to daily functioning (neurological deficits), treatment and 7-day outcome. MATERIAL AND METHODS: All patients with suspected neurovascular disease were admitted to the stroke unit as emergencies. Patients with confirmed cerebrovascular disease were prospectively included in the Bergen Stroke Study in the period 1 February 2006-30 April 2009. Patients who had other diagnoses were not included, but their diagnoses were prospectively recorded in a 3 month-period. RESULTS: 49.8% of the patients had other diagnoses than acute stroke. Of 1101 patients with neurovascular disease; 10% had transient ischemic attacks, 79% had ischemic and 10% had hemorrhagic stroke. On admission, 72% of the patients had none or minor neurological deficits. After one week 63% of the patients were independent, 25% needed long-term rehabilitation and 10% were bedridden. INTERPRETATION: Most patients in our study had mild deficits and first of all need an exact diagnostic work-up, acute and prophylactic treatment. Rehabilitation is important for a minority of patients.


Subject(s)
Cerebrovascular Disorders , Stroke , Acute Disease , Adolescent , Adult , Aged , Aged, 80 and over , Cerebrovascular Disorders/diagnosis , Cerebrovascular Disorders/rehabilitation , Cerebrovascular Disorders/therapy , Emergencies , Female , Hospital Units , Humans , Intracranial Hemorrhages/diagnosis , Intracranial Hemorrhages/therapy , Ischemic Attack, Transient/diagnosis , Ischemic Attack, Transient/therapy , Male , Middle Aged , Outcome Assessment, Health Care , Patient Admission , Prospective Studies , Stroke/diagnosis , Stroke/therapy , Stroke Rehabilitation , Young Adult
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