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1.
Am J Gastroenterol ; 116(2): 407-410, 2021 02 01.
Article in English | MEDLINE | ID: mdl-33136569

ABSTRACT

INTRODUCTION: Per-oral endoscopic myotomy (POEM) is an effective modality for the management of achalasia. Tension pneumoperitoneum is a significant complication that causes hemodynamic instability, generally within the periprocedural period. METHODS: Here, we report 2 cases of delayed tension pneumoperitoneum that was recognized and treated several hours after uncomplicated POEM. RESULTS: These cases illustrate the importance of continued vigilance for this complication outside of the immediate periprocedural period as well as the utility of computed tomography-guided aspiration in managing it. DISCUSSION: When discharging patients after POEM, caregivers should be aware of this rare complication and alert patients to return for immediate care when it happens.


Subject(s)
Esophageal Achalasia/surgery , Myotomy/methods , Natural Orifice Endoscopic Surgery , Pneumoperitoneum/diagnostic imaging , Postoperative Complications/diagnostic imaging , Abdominal Pain/physiopathology , Chest Pain/physiopathology , Decompression, Surgical , Dyspnea/physiopathology , Endoscopy, Digestive System/methods , Female , Humans , Mediastinal Emphysema/diagnostic imaging , Mediastinal Emphysema/physiopathology , Middle Aged , Mouth , Needles , Pneumoperitoneum/physiopathology , Pneumoperitoneum/surgery , Pneumothorax/diagnostic imaging , Pneumothorax/physiopathology , Postoperative Complications/physiopathology , Postoperative Complications/surgery , Punctures , Subcutaneous Emphysema/diagnostic imaging , Subcutaneous Emphysema/physiopathology
2.
Am J Emerg Med ; 49: 14-17, 2021 Nov.
Article in English | MEDLINE | ID: mdl-34034203

ABSTRACT

INTRODUCTION: Lung ultrasound is commonly used for the diagnosis of pneumothorax. However, recognition of pleural sliding is subjective and can be difficult for novice. The primary objective was to compare a novices physician's performance in diagnosing pneumothorax from ultrasound (US) scans either with visual evaluation or with maximum longitudinal pleural strain (MLPS). The secondary objective was to compare the diagnostic relevance of US with visual evaluation or MLPS to diagnose pneumothorax with an intermediately experienced and an expert physician. METHODS: We conducted a prospective, observational study in two emergency department and two intensive care unit, between February 2019 and June 2020. We included 99 adult patients with suspected pneumothorax, who received a chest computed tomography (CT). Three physicians with different experience of interpreting US scans (a novice physician, an intermediately experienced physician, and an expert) analyzed the US scans of 99 patients with suspected pneumothorax (50 (51%) with confirmed pneumothorax), which were confirmed by CT scan. RESULTS: With a threshold of 5%, the MLPS sensitivity was 94% (95% CI [83%; 98%]), and the specificity was 100% (95% CI [93%; 100%]). The novice physician had an area under the curve (AUC) with visual analysis of 0.75 (95% CI [0.67; 0.83]) vs 0.86 (95% CI [0.79; 0.94]) with MLPS (p = 0.04). The intermediate physician's AUC for diagnosing pneumothorax with visual analysis was 0.93 (95% CI [0.88; 0.99]) vs 1.00 (95% CI [1.00; 1.00]) with MLPS (p < 0.01) and for the expert physician it was 0.98 (95% CI [0.95;1.00]) vs 0.97 (95% CI [0.93; 1.00]), respectively (p = 0.69). CONCLUSION: In our study, speckle tracking analysis improved the accuracy of US for the novice and the intermediate but not the expert sonographer in the diagnosis of pneumothorax.


Subject(s)
Pneumothorax/diagnostic imaging , Pneumothorax/diagnosis , Ultrasonography/standards , Adult , Aged , Area Under Curve , Chi-Square Distribution , Emergency Service, Hospital/organization & administration , Emergency Service, Hospital/statistics & numerical data , Female , Humans , Lung/diagnostic imaging , Male , Middle Aged , Pneumothorax/physiopathology , Prospective Studies , ROC Curve , Statistics, Nonparametric , Tomography, X-Ray Computed/methods , Ultrasonography/methods , Ultrasonography/statistics & numerical data
3.
Thorac Cardiovasc Surg ; 69(1): 95-100, 2021 01.
Article in English | MEDLINE | ID: mdl-32199405

ABSTRACT

INTRODUCTION: Spontaneous pneumothorax occurs rarely during pregnancy with less than 100 cases reported in the English literature. There is no strong evidence concerning the treatment of spontaneous pneumothorax during pregnancy and labor. The aim of this study is to systematically review all the reported cases and to suggest recommendations for its diagnosis and treatment. METHODS: A PubMed research was conducted. The following data were collected: maternal age, gestation age (weeks), presence of underlying lung pathology, initial management, definitive management, obstetric outcome, and the complications for the mother and the fetus. RESULTS: Eighty-seven cases were identified. The mean maternal age was 27 years (standard deviation [SD] ± 6). The mean gestational age was 25 weeks (SD ± 11.4). In 37.9% of cases, there was no underlying lung disease. In the majority of cases (67.4%), the initial treatment was the placement of a chest tube. In 48% of cases, the pneumothorax was resolved with conservative treatment. Surgical therapy was performed either antepartum or postpartum. In 58.6% of cases, there was a vaginal delivery, spontaneous or instrumental. In three cases (3.4%), there were fetal complications. CONCLUSION: The analysis of the current literature provides low evidence, since there are only case reports and small case series. It is likely that the frequency of this condition is underestimated. However, this analysis permits to draw some conclusions concerning the timing of pneumothorax treatment, the operative strategy, and the mode of delivery to decrease the risk for the mother and the fetus.


Subject(s)
Chest Tubes , Conservative Treatment , Pneumothorax/therapy , Pregnancy Complications/therapy , Thoracic Surgery, Video-Assisted , Adult , Consensus , Conservative Treatment/adverse effects , Female , Humans , Pneumothorax/diagnosis , Pneumothorax/etiology , Pneumothorax/physiopathology , Pregnancy , Pregnancy Complications/diagnosis , Pregnancy Complications/etiology , Pregnancy Complications/physiopathology , Risk Factors , Thoracic Surgery, Video-Assisted/adverse effects , Treatment Outcome , Young Adult
4.
BMC Pulm Med ; 21(1): 20, 2021 Jan 09.
Article in English | MEDLINE | ID: mdl-33422030

ABSTRACT

BACKGROUND: Spontaneous pneumothorax is a common problem globally. Bullas and blebs have been implicated in this problem, but the etiology of their formation is unknown. We aim to show the relation between a novel clinical finding, the pulmonary delayed inflation (PDI) sign, and the etiology of bulla and bleb formation in young patients. METHODS: We retrospectively analyzed data from 111 patients with pneumothorax and a control group of 27 patients. We evaluated the relation between the PDI sign and other clinical factors. RESULTS: The PDI sign was observed in 78 patients. Of these, 75 exhibited the PDI sign in only the upper lobe. Regardless of smoking status, patients 34 years of age or younger had a significantly higher incidence of the PDI sign than, patients 55 years of age or older and control patients. The inflation time in patients 34 years of age or younger, regardless of smoking status, was significantly longer than in patients 55 years of age or older and patients in the control group. There was no significant association between inflation time and the presence of asthma. CONCLUSIONS: The novel PDI sign is seen in patients 34 years of age or younger. Because this sign may indicate a peripheral bronchial abnormality and may be related to the formation of blebs and bullae in young patients with spontaneous pneumothorax, it is possible that it can be used to develop effective treatments for pneumothorax in young patients.


Subject(s)
Lung , Pneumothorax , Adult , Female , Humans , Male , Middle Aged , Age Factors , Lung/physiopathology , Lung/surgery , Pneumothorax/physiopathology , Pneumothorax/surgery , Retrospective Studies , Smoking , Thoracic Surgery, Video-Assisted , Time Factors , Video Recording
5.
Adv Skin Wound Care ; 34(4): 1-6, 2021 Apr 01.
Article in English | MEDLINE | ID: mdl-33739953

ABSTRACT

ABSTRACT: Patients with extensive deep burns usually experience infections and organ dysfunction. Proactive and effective wound repair is key to treatment. If large wounds remain open, systemic infection and multiple organ dysfunction syndrome can occur, threatening the lives of patients. Current wound repair methods include skin grafts, flap repair, negative-pressure wound therapy, and cellular and/or tissue-based products. For deep, complex burn wounds, a single form of treatment is usually ineffective. This article reports a rare case of burn wound repair. The patient was burned by a charcoal flame on multiple parts of his body after carbon monoxide poisoning. Pneumothorax and acute renal failure occurred after the injury, accompanied by multiple osteonecroses of the trunk and lower limbs. A multidisciplinary team formulated an individualized treatment plan; the diverse treatments included closed chest drainage, continuous renal replacement therapy, infection control, analgesia, wound debridement, negative-pressure wound therapy, cellular and/or tissue-based products, autologous dermal scaffold graft, skin grafts, flap transposition, platelet-rich plasma, and rehabilitation, which ultimately saved the patient's life and led to healing of all the wounds.


Subject(s)
Burns/etiology , Carbon Monoxide Poisoning/complications , Acute Kidney Injury/etiology , Acute Kidney Injury/physiopathology , Adult , Coma/etiology , Debridement/methods , Fires , Humans , Male , Pneumothorax/etiology , Pneumothorax/physiopathology , Treatment Outcome , Wound Healing/drug effects , Wound Healing/physiology
6.
Undersea Hyperb Med ; 47(4): 555-560, 2020.
Article in English | MEDLINE | ID: mdl-33227831

ABSTRACT

A diver practicing controlled emergency ascent training on the island of Guam suffered bilateral pneumothorax, pneumomediastinum, coronary arterial gas embolism, and developed multiple organ dysfunction syndrome. Due to limitations of available resources he was medically managed in the intensive care unit until he could be transferred to University of California San Diego for definitive management. We provide an account of our management of the patient, the pathophysiology of injury as well as a review of the safety of recreational diving skills training, current standards of practice and potential pitfalls when considering proper management of a critically injured diver.


Subject(s)
Barotrauma/therapy , Coronary Disease/therapy , Diving/injuries , Embolism, Air/therapy , Mediastinal Emphysema/therapy , Multiple Organ Failure/therapy , Pneumothorax/therapy , Adult , Barotrauma/physiopathology , Coronary Disease/physiopathology , Coronary Thrombosis/etiology , Diving/adverse effects , Diving/physiology , Embolism, Air/etiology , Embolism, Air/physiopathology , Emergencies , Fatal Outcome , Guam , Health Services Accessibility , Humans , Male , Mediastinal Emphysema/physiopathology , Multiple Organ Failure/physiopathology , Pneumothorax/physiopathology , Recreation , Respiratory Distress Syndrome/etiology , Respiratory Distress Syndrome/therapy , Syndrome , Tachycardia/diagnosis , Tachycardia/etiology , Transportation of Patients/organization & administration , Venous Thromboembolism/prevention & control
7.
Med J Malaysia ; 75(2): 181-183, 2020 03.
Article in English | MEDLINE | ID: mdl-32281606

ABSTRACT

In the past, many case series have reported the effectiveness of autologous blood patch pleurodesis (ABPP) in recurrent secondary spontaneous pneumothorax (SSP), particularly in those who were unfit for surgery. We describe two cases of persistent air leak in pneumoconiosis and pulmonary fibrosis with bronchiectasis, whereby the techniques employed had improved the success rate of ABPP. The determining factors that lead to the success of ABPP were determined by the volume of autologous blood instilled, Trendelenburg position post instillation, and early chest physiotherapy with mobilisation by application of pneumostat.


Subject(s)
Blood Transfusion, Autologous/methods , Pleurodesis/methods , Pneumothorax/therapy , Adult , Aged, 80 and over , Female , Humans , Lung Diseases/physiopathology , Lung Diseases/therapy , Malaysia , Male , Pneumothorax/physiopathology , Treatment Outcome
8.
Med Sci Monit ; 25: 8482-8491, 2019 Nov 11.
Article in English | MEDLINE | ID: mdl-31708570

ABSTRACT

BACKGROUND Primary spontaneous pneumothorax (PSP) is reported to be more common in young men who are thin and tall. This retrospective study aimed to analyze the clinical and chest wall characteristics associated with PSP. MATERIAL AND METHODS Between January 2008 to December 2017, the clinical and imaging data of 99 patients at first presentation with PSP were compared with 82 age-matched healthy controls. Computed tomography (CT) imaging was used to measure the anteroposterior and transverse diameters of the chest at four levels, including the aortic arch, tracheal bifurcation, right inferior pulmonary vein, and lower sternal edge. Chest deformity was calculated as the ratio of the transverse diameter of the hemithorax divided by anteroposterior diameter. Lung volume and average lung density of 32 cases with PSP were measured and compared with 10 patients without PSP. Intrapleural pressure of 43 cases PSP who were treated with a closed chest drain was measured and compared with 39 patients with mediastinal tumor who underwent thoracoscopic surgery. RESULTS Patients with PSP showed a normal age distribution with a median of 17-18 years. The patients with PSP had significantly reduced anteroposterior and transverse diameters of the chest when compared with controls at four levels on CT (p<0.01). The lung volumes in patients with PSP were significantly reduced when compared with the controls (p<0.05), as were the minimum intrapleural pressure and pressure difference (p<0.05). CONCLUSIONS The findings support that chest wall dimensions may be associated with lung development, which are contributing factors in PSP.


Subject(s)
Lung/pathology , Pneumothorax/physiopathology , Thoracic Wall/pathology , Adolescent , Adult , Case-Control Studies , Female , Humans , Male , Retrospective Studies , Risk Factors , Tomography, X-Ray Computed/methods , Young Adult
9.
Respiration ; 97(5): 436-443, 2019.
Article in English | MEDLINE | ID: mdl-30904909

ABSTRACT

BACKGROUND: Optimal management of persistent air leaks (PALs) in patients with secondary spontaneous pneumothorax (SSP) remains controversial. OBJECTIVE: To evaluate the efficacy and safety of endobronchial autologous blood plus thrombin patch (ABP) and bronchial occlusion using silicone spigots (BOS) in patients with SSP accompanied by alveolar-pleural fistula (APF) and PALs. METHODS: This prospective multicentre randomized controlled trial compared chest tube-attached water-seal drainage (CTD), ABP, and BOS that were performed between February 2015 and June 2017 in one of six tertiary care hospitals in China. Patients diagnosed with APF experiencing PALs (despite 7 days of CTD) and inoperable patients were included. Outcome measures included success rate of pneumothorax resolution at the end of the observation period (further 14 days), duration of air leak stop, lung expansion, hospital stay, and complications. RESULTS: In total, 150 subjects were analysed in three groups (CTD, ABP, BOS) of 50 each. At 14 days, 60, 82, and 84% of CTD, ABP, and BOS subjects, respectively, experienced full resolution of pneumothorax (p = 0.008). All duration outcome measures were significantly better in the ABP and BOS groups than in the CTD group (p < 0.016 for all). The incidence of adverse events, including chest pain, cough, and fever, was not significantly different. All subjects in the ABP and BOS groups experienced temporary haemoptysis. Spigot displacement occurred in 8% of BOS subjects. CONCLUSION: ABP and BOS resulted in clinically meaningful outcomes, including higher success rate, duration of air leak stop, lung expansion, and hospital stay, with an acceptable safety profile.


Subject(s)
Bronchoscopy/methods , Pneumothorax , Postoperative Complications , Respiratory Tract Fistula , Thoracentesis , Aged , Bioprosthesis , Chest Tubes/adverse effects , Drainage/methods , Female , Humans , Male , Middle Aged , Pleural Diseases/complications , Pneumothorax/diagnosis , Pneumothorax/etiology , Pneumothorax/physiopathology , Pneumothorax/therapy , Postoperative Complications/diagnosis , Postoperative Complications/therapy , Respiratory Tract Fistula/etiology , Respiratory Tract Fistula/therapy , Thoracentesis/adverse effects , Thoracentesis/instrumentation , Thoracentesis/methods , Treatment Outcome
10.
Lung ; 197(5): 627-633, 2019 10.
Article in English | MEDLINE | ID: mdl-31463549

ABSTRACT

PURPOSE: Air leaks are common after lobectomy, segmentectomy, and lung volume reduction surgery (LVRS). This can increase post-operative morbidity, cost, and hospital length of stay. The management of post-pulmonary resection air leaks remains challenging. Minimally invasive effective interventions are necessary. The Spiration Valve System (SVS, Olympus/Spiration Inc., Redmond, WA, US) is approved by the FDA under humanitarian use exemption for management of prolonged air leaks. METHODS: This is a prospective multicenter registry of 39 patients with air leaks after lobectomy, segmentectomy, and LVRS managed with an intention to use bronchoscopic SVS to resolve air leaks. RESULTS: Bronchoscopic SVS placement was feasible in 82.1% of patients (32/39 patients) and 90 valves were placed with a median of 2 valves per patient (mean of 2.7 ± 1.5 valves, range of 1 to 7 valves). Positive response to SVS placement was documented in 76.9% of all patients (30/39 patients) and in 93.8% of patients when SVS placement was feasible (30/32 patients). Air leaks ultimately resolved when SVS placement was feasible in 87.5% of patients (28/32 patients), after a median of 2.5 days (mean ± SD of 8.9 ± 12.4 days). Considering all patients with an intention to treat analysis, bronchoscopic SVS procedure likely contributed to resolution of air leaks in 71.8% of patients (28/39 patients). The post-procedure median hospital stay was 4 days (mean 6.0 ± 6.1 days). CONCLUSIONS: This prospective registry adds to the growing body of literature supporting feasible and effective management of air leaks utilizing one-way valves.


Subject(s)
Bronchoscopy/instrumentation , Pneumonectomy/adverse effects , Pneumothorax/therapy , Aged , Bronchoscopy/adverse effects , Feasibility Studies , Female , Humans , Length of Stay , Male , Middle Aged , Pneumonectomy/instrumentation , Pneumothorax/diagnosis , Pneumothorax/etiology , Pneumothorax/physiopathology , Prospective Studies , Recovery of Function , Registries , Risk Factors , Time Factors , Treatment Outcome , United States
11.
Am J Emerg Med ; 37(1): 173.e1-173.e2, 2019 01.
Article in English | MEDLINE | ID: mdl-30509377

ABSTRACT

Spontaneous pneumothorax (SP) is a relatively common pathology in emergency medicine; however, scant information is published regarding SPs developing tension physiology in the literature. Risk factors for spontaneous pneumothorax include smoking, family history, and underlying lung disease such as chronic obstructive lung disease (COPD), cystic fibrosis, tuberculosis, among others. Treatment often involves conservative management, needle aspiration, catheter placement, or tube thoracostomy. Tension pneumothorax, however, is a life threatening condition requiring emergent intervention. Case reports have demonstrated large SPs with midline shift but without tension physiology as patients largely remained hemodynamically stable. We report the case of an 18-year-old male presenting to the Emergency Department (ED) with a SP that rapidly developed tension physiology with mediastinal shift and hypotension resolved by needle decompression and CT placement.


Subject(s)
Pneumothorax/etiology , Pneumothorax/surgery , Adolescent , Chest Tubes , Decompression, Surgical/methods , Emergency Service, Hospital , Humans , Male , Needles , Pneumothorax/diagnostic imaging , Pneumothorax/physiopathology , Thoracic Surgery, Video-Assisted
12.
BMC Pulm Med ; 19(1): 267, 2019 Dec 30.
Article in English | MEDLINE | ID: mdl-31888739

ABSTRACT

BACKGROUND: The initial management of pneumothorax remains controversial, and we speculated that this might be because there is no method available for evaluation of air leak during initial management. We have developed a system for measurement of intrapleural pressure in pneumothorax to address air leak without the need for chest drainage. The aim of this clinical study was to confirm the ability of this measurement system and to determine the clinical impact of management of air leak. METHODS: Patients in whom need aspiration was indicated for spontaneous pneumothorax were enrolled in the study. The intrapleural pressure was measured during stable breathing and data recorded when patients were coughing were excluded. RESULTS: Eleven patients were enrolled in the study between December 2016 to July 2017. The patterns in change of intrapleural pressure varied widely depending on the state of the pneumothorax. The mean intrapleural pressure values on end-inspiration and end-expiration in patients with persistent air leak was significantly lower than those in patients without persistent air leak (p = 0.020). The number of negative mean pressure recordings in end-inspiration and end-expiration was significantly lower in patients with persistent air leak than in those without persistent air leak (p = 0.0060). CONCLUSIONS: In this study, we demonstrated that intrapleural pressure could be successfully measured and visualized in patients with pneumothorax. Whether or not the pressure value is a predictor of persistent air leak needs to be confirmed in the future.


Subject(s)
Pleural Cavity/physiopathology , Pneumothorax/physiopathology , Adult , Aged , Diagnostic Techniques, Respiratory System , Female , Humans , Male , Middle Aged , Pilot Projects , Pressure , Retrospective Studies , Young Adult
13.
Respirology ; 23(5): 519-525, 2018 May.
Article in English | MEDLINE | ID: mdl-29130562

ABSTRACT

BACKGROUND AND OBJECTIVE: Pneumothorax is a co-morbidity in patients with idiopathic pulmonary fibrosis (IPF). However, its incidence, risk factors and prognostic significance in IPF remain unclear. The aim of this study was to clarify the incidence and prognostic significance of pneumothorax in patients with IPF, and to further investigate the risk factors for its onset. METHODS: Eighty-four consecutive patients with IPF based on the consensus guideline were included in this study. We retrospectively reviewed the medical records, pulmonary function tests and chest high-resolution computed tomography images, and determined the incidence of pneumothorax. The prognostic significance of pneumothorax was evaluated using the Cox proportional hazards model analysis with time-dependent covariates. We also assessed the cumulative incidence and the risk factors for pneumothorax. RESULTS: Of the 84 patients, 17 (20.2%) developed pneumothorax. The cumulative incidence of pneumothorax was 8.5%, 12.5% and 17.7% at 1, 2 and 3 years, respectively. Univariate analysis demonstrated that pneumothorax was significantly related to poor prognosis (hazards ratio, 2.99; P = 0.002). Multivariate analysis, adjusting for sex, age and forced vital capacity (% predicted), revealed that pneumothorax was an independent predictor of poor outcome in IPF (hazards ratio, 2.85; P = 0.006). Lower BMI and the presence of extensive reticular abnormalities were significantly associated with developing pneumothorax. CONCLUSION: These results confirm that patients with IPF often develop pneumothorax during their clinical course and that the onset of pneumothorax predicts a poor outcome.


Subject(s)
Idiopathic Pulmonary Fibrosis/epidemiology , Pneumothorax/epidemiology , Aged , Aged, 80 and over , Body Mass Index , Comorbidity , Female , Humans , Idiopathic Pulmonary Fibrosis/diagnostic imaging , Idiopathic Pulmonary Fibrosis/physiopathology , Incidence , Male , Middle Aged , Pneumothorax/diagnostic imaging , Pneumothorax/physiopathology , Prognosis , Proportional Hazards Models , Retrospective Studies , Risk Factors , Time Factors , Tomography, X-Ray Computed
14.
Lung ; 196(6): 715-720, 2018 12.
Article in English | MEDLINE | ID: mdl-30187131

ABSTRACT

INTRODUCTION: Pneumothorax often develops in pulmonary Langerhans cell histiocytosis (PLCH), but some patients take a long time to be correctly diagnosed. OBJECTIVES: This study assessed the frequency of pneumothorax in PLCH and analysed the role of chest computed tomography (CT) in the prompt diagnosis. PATIENTS AND MATERIAL: Of the 90 patients with PLCH seen from 2000 to 2015, 29 (32%) had pneumothorax as the initial finding. In this group, 18 (62%) patients were diagnosed within 1 month, whereas the diagnosis was delayed for 4-120 months in 11 (38%) patients. RESULTS: Patients who had pneumothorax as the initial sign of PLCH tended to be younger (mean age 27.7 ± 7.92 vs. 39.9 ± 13.21 years; P = 0.0001), male (69% vs. 43%; P = 0.028), smoked less (mean pack/years 8.4 ± 6.85 vs. 19 ± 17.16; P = 0.003), and had a significantly lower mean FVC (77.96 ± 19.62 vs. 89.47 ± 21.86% pred.; P = 0.015) and FEV1 (68.6 ± 19.93 vs. 79.4 ± 21.48% pred.; P = 0.03 than patients who had no pneumothorax. Recurrent pneumothorax was diagnosed more frequently in the group with a delayed diagnosis (82% vs. 39%; P = 0.02). CT was performed in all of the patients who were diagnosed promptly, but in none of the patients with a delayed diagnosis. CONCLUSIONS: Patients who had pneumothorax as the initial sign of PLCH were younger, more frequently men, and had greater respiratory impairment than those who had no pneumothorax. CT in patients with pneumothorax led to a correct diagnosis of this disease.


Subject(s)
Histiocytosis, Langerhans-Cell/complications , Histiocytosis, Langerhans-Cell/diagnostic imaging , Pneumothorax/diagnostic imaging , Pneumothorax/etiology , Adult , Age Factors , Delayed Diagnosis , Female , Forced Expiratory Volume , Histiocytosis, Langerhans-Cell/physiopathology , Humans , Male , Middle Aged , Pneumothorax/physiopathology , Recurrence , Sex Factors , Tomography, X-Ray Computed , Vital Capacity , Young Adult
15.
Paediatr Anaesth ; 28(5): 468-470, 2018 05.
Article in English | MEDLINE | ID: mdl-29603862

ABSTRACT

Intraoperative pneumothorax during general anesthesia is a dangerous event. It is a possible cause of sudden intraoperative hypoxia, which can be critical especially in high-risk patients such as those with end-stage heart failure. Early diagnosis and effective treatment are essential. We describe the case of a pneumothorax during cardiac transplantation, diagnosed by ultrasound and immediately treated. A good skill in lung ultrasound is advantageous in the management of intraoperative hypoxia, particularly for prompt diagnosis of pneumothorax.


Subject(s)
Hypoxia/etiology , Lung/diagnostic imaging , Pneumothorax/physiopathology , Adolescent , Female , Humans , Hypoxia/diagnostic imaging , Intraoperative Complications/diagnostic imaging , Intraoperative Complications/etiology , Pneumothorax/diagnostic imaging , Ultrasonography
16.
G Chir ; 39(6): 375-377, 2018.
Article in English | MEDLINE | ID: mdl-30563601

ABSTRACT

AIM: The purpose of this study is to determine the anatomical aspects, mechanisms, risk factors and appropriate management of development of pneumothorax during a routine colonoscopy. CLINICAL CASE: We report a case of an accidental bowel wall injury during diagnostic colonoscopic with consequent pneumoperitoneum; this was followed by expansion of gas through diaphragmatic fenestration perhaps congenital, in right pleural cavity causing pneumothorax. DISCUSSION: Rarely, colonic perforation during colonoscopy can occur into the extraperitoneal space, thus leading to the passage and diffusion of air along the fascial planes and large vessels, possibly causing pneumoretroperitoneum, pneumomediastinum, pneumopericardium, pneumothorax, and subcutaneous emphysema. The combination of intraperitoneal and extraperitoneal perforation has also been reported. Pneumothorax following a colonoscopy sigmoid perforation is an extremely rare but severe and often lifethreatening complication. CONCLUSION: If the patient develops dyspnea and pneumoderma during or after this procedure, a chest radiogram or thoracoabdominal CT should be taken for diagnostic purposes. Urgent treatment, starting with chest tube insertion(s) and laparotomy or laparoscopy could be lifesaving.


Subject(s)
Colon, Sigmoid/injuries , Colonoscopy/adverse effects , Intestinal Perforation/etiology , Pneumothorax/etiology , Abdomen, Acute/etiology , Diaphragm/pathology , Emergencies , Female , Humans , Middle Aged , Pneumoperitoneum/diagnostic imaging , Pneumoperitoneum/etiology , Pneumothorax/diagnostic imaging , Pneumothorax/physiopathology , Tomography, X-Ray Computed
17.
BMC Cancer ; 17(1): 317, 2017 05 05.
Article in English | MEDLINE | ID: mdl-28476108

ABSTRACT

BACKGROUND: To evaluate the procedures and complications of diaphragm peritonectomy (DP) and diaphragm full-thickness resection (DFTR) during primary cytoreduction for advanced stage epithelial ovarian cancer. METHODS: All the patients with epithelial ovarian carcinoma who underwent diaphragm procedures at our institution between January 2009 and August 2015 were identified. Clinicopathological data were retrospectively collected from the patients' medical records. Postoperative morbidities were assessed according to the Memorial Sloan-Kettering Cancer Center (MSKCC) grading system. RESULTS: A total of 150 patients were included in the study. The majority of the patients had ovarian cancer (96%), stage IIIC disease (76%) and serous histology (89.3%). DP and DFTR were performed in 124 (82.7%) and 26 (17.3%) patients, respectively. A total of 142 upper abdominal procedures in addition to the diaphragmatic surgery were performed in 77 (51.3%) patients. No macroscopic residual disease was observed in 35.3% of the patients, while 84% of the total patient cohort had residual disease ≤1 cm. The overall incidence of at least one major morbidity (MSKCC grades 3-5) was 18.0%, whereas pleural effusions (33.3%), pneumonia (15.3%) and pneumothorax (7.3%) were the most commonly reported morbidities. The rate of postoperative pleural drainage was 14.6% in total, while half the patients in the DFTR group received drainage intraoperatively (11.5%) and postoperatively (38.5%). The incidence of postoperative pleural effusion was associated with stage IV disease (hazard ratio [HR], 17.2; 95% confidence interval [CI]: 4.5-66.7; P < 0.001), DFTR (HR, 4.9; 95% CI: 1.2-19.9; P = 0.028) and a long surgery time (HR, 15.4; 95% CI: 4.3-55.5; P < 0.001). CONCLUSIONS: Execution of DP and DFTR as part of an extensive upper abdominal procedure resulted in an acceptable morbidity rate. Pleural effusion, pneumonia and pneumothorax were the most common pulmonary morbidities. The pleural drainage rate was not high enough to justify prophylactic chest tube placement for all the patients. However, patients who underwent DFTR merited special consideration for intraoperative prophylactic drainage.


Subject(s)
Cytoreduction Surgical Procedures , Diaphragm/surgery , Neoplasm Metastasis/pathology , Ovarian Neoplasms/surgery , Adult , Aged , China , Diaphragm/physiopathology , Drainage , Fallopian Tube Neoplasms/mortality , Fallopian Tube Neoplasms/physiopathology , Fallopian Tube Neoplasms/surgery , Female , Humans , Middle Aged , Neoplasm Staging , Ovarian Neoplasms/mortality , Ovarian Neoplasms/physiopathology , Peritoneal Neoplasms/mortality , Peritoneal Neoplasms/physiopathology , Peritoneal Neoplasms/surgery , Pleural Effusion , Pneumothorax/physiopathology , Pneumothorax/surgery
18.
Acta Anaesthesiol Scand ; 61(7): 813-823, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28555810

ABSTRACT

INTRODUCTION: Advanced life support (ALS) guidelines recommend ultrasound to identify reversible causes of cardiac arrest. Right ventricular (RV) dilatation during cardiac arrest is commonly interpreted as a sign of pulmonary embolism. The RV is thus a focus of clinical ultrasound examination. Importantly, in animal studies ventricular fibrillation and hypoxia results in RV dilatation. Tension pneumothorax (tPTX) is another reversible cause of cardiac arrest, however, the impact on RV diameter remains unknown. AIM: To investigate RV diameter evaluated by ultrasound in cardiac arrest caused by tPTX or hypoxia. METHODS: Pigs were randomized to cardiac arrest by either tPTX (n = 9) or hypoxia (n = 9) and subsequently resuscitated. Tension pneumothorax was induced by injection of air into the pleural cavity. Hypoxia was induced by reducing tidal volume. Ultrasound images of the RV were obtained throughout the study. Tension pneumothorax was decompressed after the seventh rhythm analysis. The primary endpoint was RV diameter after the third rhythm analysis. RESULTS: At cardiac arrest the RV diameter was 17 mm (95% CI: 13; 21) in the tPTX group and 36 mm (95% CI: 33; 40) in the hypoxia group (P < 0.01, n = 9 for both). At third rhythm analysis RV diameter was smaller in the tPTX group: 12 mm (95% CI: 7; 16) vs. hypoxia group: 28 mm (25; 32) (P < 0.01). After decompression no difference existed between groups: tPTX 29 mm (95% CI: 23; 34) vs. hypoxia 29 mm (95% CI: 20; 38). CONCLUSION: The RV diameter is smaller during cardiopulmonary resuscitation in cardiac arrest caused by tPTX when compared with hypoxia. The difference disappears after tPTX decompression.


Subject(s)
Heart Arrest/etiology , Heart Ventricles/diagnostic imaging , Heart Ventricles/physiopathology , Pneumothorax/complications , Ultrasonography/methods , Animals , Disease Models, Animal , Female , Heart Arrest/physiopathology , Pneumothorax/physiopathology , Swine
19.
Am J Emerg Med ; 35(8): 1210.e1-1210.e4, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28438445

ABSTRACT

Pneumothorax can cause a variety of electrocardiographic changes. ST segment elevation, which is mainly observed in myocardial infarction, can also be induced by pneumothorax. The mechanism is presumed to be a decrease in cardiac output, due to increased intra-thoracic pressure. We encountered a patient with ST segment elevation with minimal pneumothorax. Coronary angiography with ergonovine provocation test and echocardiogram had normal findings. The ST segment elevation was normalized by decreasing the amount of pneumothorax. We reviewed the literature and present possible mechanisms for this condition.


Subject(s)
Electrocardiography , Pneumothorax/physiopathology , Radiography, Thoracic/methods , ST Elevation Myocardial Infarction/physiopathology , Adult , Chest Pain , Humans , Male , Pneumothorax/complications , Pneumothorax/diagnostic imaging , ST Elevation Myocardial Infarction/diagnostic imaging , ST Elevation Myocardial Infarction/etiology , Treatment Outcome
20.
J Emerg Med ; 53(2): 241-247, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28372830

ABSTRACT

BACKGROUND: Although air has traditionally been considered a barrier to sonographic imaging, when encountered in unusual settings it can serve as an important indicator of various pathologic states as well. Clinician recognition and thorough understanding of the characteristic pattern of artifacts generated by air are critical for making a number of important diagnoses. CASE SERIES: We present five emergency department cases in which air was visualized in a pathologic location. Pneumothorax, pneumoperitoneum, necrotizing fasciitis, or Fournier's gangrene, and subcutaneous emphysema and pneumomediastinum, can be rapidly and easily identified on ultrasound by the presence of air artifacts. The relevant sonographic findings are described and discussed in this article. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Due to its inherent impedance mismatch with other human tissues, air has a characteristic appearance on ultrasound that includes irregular hyperechoic structures, "dirty shadowing," A-lines, and decreased visualization of deeper structures. Knowledge of the sonographic appearance of air artifacts can assist the physician in making a diagnosis, selecting appropriate additional imaging, and enlisting specialist consultation.


Subject(s)
Air/analysis , Ultrasonography/methods , Adult , Aged , Fasciitis, Necrotizing/diagnosis , Fasciitis, Necrotizing/physiopathology , Female , Fournier Gangrene/diagnosis , Fournier Gangrene/physiopathology , Humans , Male , Mediastinal Emphysema/diagnosis , Mediastinal Emphysema/physiopathology , Middle Aged , Pneumoperitoneum/diagnosis , Pneumoperitoneum/physiopathology , Pneumothorax/diagnosis , Pneumothorax/physiopathology , Point-of-Care Systems/trends , Subcutaneous Emphysema/diagnosis , Subcutaneous Emphysema/physiopathology
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