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Bioprocess Biosyst Eng ; 44(11): 2407-2415, 2021 Nov.
Article in English | MEDLINE | ID: mdl-34272979

ABSTRACT

The physical and chemical properties of Nickel oxide nanoparticles (NiO-NPs) have attracted the attention of many and in this regard, this study was performed to produce NiO-NPs by the means of Salvia hispanica L. (chia) seeds extract as the capping agent. Physical and morphological features of the obtained NiO-NPs were examined through the application of TGA, FTIR, UV-Vis, XRD, FESEM/EDAX/PSA, and VSM procedures. According to the FESEM/PSA images, the biosynthesized NiO-NPs contained a spherical shape and a size of about 30 nm, while the results of the EDAX study approved the existence of oxygen and nickel elements in the structure of this product. Furthermore, certain corresponding peaks to the crystal structure of NiO-NPs were observed throughout the XRD pattern. Next to the superparamagnetic behavior that was detected in the results of VSM analysis, the cytotoxicity effect of NiO-NPs was not reported to be dependent on concentration. Considering the high photocatalytic capacity along with the low cytotoxic effects of NiO-NPs, we can suggest the applicability of this product for various applications such as disease control and removal of residual toxins.


Subject(s)
Cell Survival/drug effects , Green Chemistry Technology , Metal Nanoparticles/chemistry , Nickel/chemistry , Plant Extracts/chemistry , Plant Extracts/pharmacology , Salvia hispanica/embryology , Seeds/chemistry , Animals , Catalysis , Drug Screening Assays, Antitumor , PC12 Cells , Rats
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