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1.
Transpl Int ; 36: 11611, 2023.
Article in English | MEDLINE | ID: mdl-38093807

ABSTRACT

Early detection of liver transplantation (LT) vascular complications enables timely management. Our aim was to assess if routine Doppler ultrasound (rDUS) improves the detection of hepatic artery thrombosis (HAT), portal vein thrombosis (PVT) and hepatic venous outflow obstruction (HVOO). We retrospectively analysed timing and outcomes, number needed to diagnose one complication (NND) and positive predictive value (PPV) of rDUS on post-operative day (POD) 0,1 and 7 in 708 adult patients who underwent primary LT between 2010-2022. We showed that HAT developed in 7.1%, PVT in 8.2% and HVOO in 3.1% of patients. Most early complications were diagnosed on POD 0 (26.9%), 1 (17.3%) and 5 (17.3%). rDUS correctly detected 21 out of 26 vascular events during the protocol days. PPV of rDUS was 53.8%, detection rate 1.1% and NND was 90.5. Median time to diagnosis was 4 days for HAT and 47 days for PVT and 21 days for HVOO. After intervention, liver grafts were preserved in 57.1%. In conclusion, rDUS protocol helps to detect first week's vascular events, but with low PPV and a high number of ultrasounds needed.


Subject(s)
Liver Diseases , Liver Transplantation , Thrombosis , Venous Thrombosis , Adult , Humans , Liver Transplantation/adverse effects , Retrospective Studies , Thrombosis/etiology , Ultrasonography/adverse effects , Venous Thrombosis/etiology , Venous Thrombosis/complications , Hepatic Artery/diagnostic imaging , Portal Vein/diagnostic imaging , Ultrasonography, Doppler/adverse effects , Postoperative Complications/diagnostic imaging , Postoperative Complications/etiology
2.
Int J Neurosci ; 133(8): 819-821, 2023 Dec.
Article in English | MEDLINE | ID: mdl-34623197

ABSTRACT

OBJECTIVE: Sphenoid sinuses mucocele (SSM) is an uncommon cause of orbital apex syndrome (OAS). Diagnosis of neurological complications in SSM might be delayed when the expansion of mucocele beyond the sinuses is not evident in conventional sinuses imaging. METHODS: We present a case of a 76-years old man with spared-pupil ophthalmoplegia associated with ptosis caused by a unilateral left SSM in which internal carotid artery Doppler ultrasound showed distal sub-occlusion waves pattern. RESULTS: Sinus occupation was noted in the magnetic resonance imaging (MRI) and was further evaluated in computed tomography (CT) scan and MR angiography. Nor CT or MR angiography showed clear evidence of neighboring structures compression. Doppler ultrasound of internal carotid showed high-resistance waveforms and decreased wave velocities helping diagnosis. Structures compression was confirmed intra-operatively and the patient was discharged asymptomatic after sphenoid sinus drainage. CONCLUSION: In this first report of carotid Doppler ultrasound findings in a patient with a neurological presentation of a sphenoid sinus mucocele, a high-resistance waveform of the internal carotid may help differentiate uncomplicated sinusitis from invasive mucocele.


Subject(s)
Blepharoptosis , Mucocele , Ophthalmoplegia , Paranasal Sinus Diseases , Male , Humans , Aged , Sphenoid Sinus/diagnostic imaging , Mucocele/complications , Mucocele/diagnostic imaging , Pupil , Ophthalmoplegia/diagnostic imaging , Ophthalmoplegia/etiology , Blepharoptosis/pathology , Magnetic Resonance Imaging , Paranasal Sinus Diseases/complications , Paranasal Sinus Diseases/diagnostic imaging , Ultrasonography, Doppler/adverse effects , Carotid Arteries
3.
West Afr J Med ; 39(4): 425-428, 2022 Apr 29.
Article in English | MEDLINE | ID: mdl-35490435

ABSTRACT

BACKGROUND: Mondor's disease (MD) is a rare cause of chest pain, characterized by thrombophlebitis of the subcutaneous veins of the anterolateral thoracoabdominal wall. It is a benign, self-limiting condition that is often underdiagnosed due to lack of knowledge of the condition. Although the exact aetiology is unclear, several predisposing factors, including excessive physical activity have been postulated. To the best of our knowledge, there is no previous published report of MD of the chest wall in an adult Nigerian man. OBJECTIVE: To describe the association between muscular strain and the development of MD. CASE PRESENTATION: A 40-year-old Nigerian man presented with a one-month history of dull, aching right-sided chest pain. He gave a history of engaging in intense thoracoabdominal exercises for 6 weeks prior to onset of symptoms. Physical examination revealed a tender, subcutaneous cord-like swelling extending from below the right anterior axillary fold to the right hypochondrium and accentuated by overhead abduction of the right arm. Ultrasonography revealed a hypoechoic, noncompressible right thoracoepigastric vein with no flow on Doppler interrogation, in keeping with superficial venous thrombosis. He was treated with nonsteroidal anti-inflammatory agents and paracetamol. The pain and lesion resolved completely within two weeks after presentation and there was no recurrence over the subsequent four months of follow-up. CONCLUSION: MD is an uncommon cause of chest pain that is often underdiagnosed and underreported due to lack of awareness. It can suddenly appear in persons performing extreme thoracoabdominal exercises. Treatment is essentially symptomatic. Prompt diagnosis of this self-limiting condition is essential in distinguishing it from malignant diseases.


CONTEXTE: La maladie de Mondor (MD) est une cause rare de douleur thoracique, caractérisée par une thrombophlébite des veines sous-cutanées de la paroi thoraco-abdominale antérolatérale. Il s'agit d'une maladie bénigne et spontanément résolutive qui est souvent sous-diagnostiquée en raison d'un manque de connaissance de la maladie. Bien que l'étiologie exacte ne soit pas claire, plusieurs facteurs prédisposants, y compris une activité physique excessive, ont été postulés. Au meilleur de notre connaissance, il n'y a aucun rapport publié précédemment de MD de la paroi thoracique chez un homme Nigérian adulte. OBJECTIF: Décrire l'association entre la tension musculaire et le développement de la MD. PRÉSENTATION DE CAS: Un homme Nigérian de 40 ans s'est présenté avec une histoire d'un mois de douleur thoracique sourde et douloureuse du côté droit. Il a indiqué qu'il s'était engagé dans des exercices thoraco-abdominaux intenses pendant 6 semaines avant l'apparition des symptômes. L'examen physique a révélé une tuméfaction sous-cutanée semblable à un cordon s'étendant du dessous du pli axillaire antérieur droit à l'hypochondre droit et accentuée par une abduction au-dessus du bras droit. L'échographie a révélé une veine thoraco-épigastrique droite hypoéchogène, non compressible et sans débit à l'examen Doppler, en rapport avec une thrombose veineuse superficielle. Il a été traité avec des anti-inflammatoires non stéroïdiens et du paracétamol. La douleur et la lésion ont complètement disparu dans les deux semaines suivant la présentation et il n'y a eu aucune récidive au cours des quatre mois suivants de suivi. CONCLUSION: La MD est une cause rare de douleur thoracique qui est souvent sous-diagnostiquée et sous-déclarée en raison d'un manque de sensibilisation. Il peut apparaître soudainement chez les personnes effectuant des exercices thoraco-abdominaux extrêmes. Le traitement est essentiellement symptomatique. Un diagnostic rapide de cette maladie spontanément résolutive est essentiel pour la distinguer des maladies malignes. Mots clés: maladie de Mondor, exercice, douleur thoracique, thrombophlébite.


Subject(s)
Thoracic Wall , Thrombophlebitis , Adult , Chest Pain/complications , Chest Pain/etiology , Humans , Male , Nigeria , Thoracic Wall/blood supply , Thoracic Wall/diagnostic imaging , Thrombophlebitis/diagnostic imaging , Thrombophlebitis/etiology , Ultrasonography, Doppler/adverse effects
4.
Actas Urol Esp (Engl Ed) ; 48(2): 177-183, 2024 Mar.
Article in English, Spanish | MEDLINE | ID: mdl-37574014

ABSTRACT

INTRODUCTION AND OBJECTIVES: Transplant renal artery stenosis (TRAS) is a vascular complication after kidney transplantation which estimated incidence is 13%. It could cause refractory arterial hypertension, kidney dysfunction and premature death in transplant recipients. METHODS: We carried out a retrospective study including every patient who underwent renal transplantation between 2014 and 2020. They were evaluated with a systematic post-transplant renal Doppler ultrasound. To identify independent risk factors for transplant renal artery stenosis we performed a multivariate analysis. RESULTS: Seven hundred twenty-four kidney transplants were included, 12% ​​were living donors and 88% were deceased donors. The mean age was 54.8 in recipients and 53 in donors. Transplant renal artery stenosis was diagnosed in 70 (10%) recipients, the majority in the first 6 months after surgery. 51% of patients with transplant renal artery stenosis were managed conservatively. The multivariate analysis showed diabetes mellitus, graft rejection, arterial resuture and donor body mass index as independent risk factors for transplant renal artery stenosis. Survival of the grafts with transplant renal artery stenosis was 98% at 6 months and 95% at two years. CONCLUSIONS: The systematic performance of Doppler ultrasound in the immediate post-transplant period diagnosed 10% of transplant renal artery stenosis in our cohort. Despite the above risk factors, an adequate monitoring and treatment could avoid the increased risk of graft loss in patients with transplant renal artery stenosis.


Subject(s)
Renal Artery Obstruction , Humans , Middle Aged , Renal Artery Obstruction/diagnostic imaging , Renal Artery Obstruction/epidemiology , Renal Artery Obstruction/etiology , Incidence , Retrospective Studies , Treatment Outcome , Risk Factors , Ultrasonography, Doppler/adverse effects
5.
Mymensingh Med J ; 32(2): 412-420, 2023 Apr.
Article in English | MEDLINE | ID: mdl-37002752

ABSTRACT

The study was intended to evaluate efficacy of Intra-arterial nitroglycerin through the sheath at the end of a transradial procedure to preserve the patency of the radial artery. This prospective observational study was done in the Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh from May 2017 to April 2018, by including a total 200 patients undergoing coronary procedures (CAG and / or PCI) through TRA. RAO was defined as an absence of antegrade flow or monophasic flow or invert flow on Doppler study. In this study 102 patients (Group I) received 200 mcg intra-arterial nitroglycerine, prior to trans-radial sheath removal. Another 98 patients (Group II) did not receive intra-arterial nitroglycerine prior to trans-radial sheath removal. Conventional haemostatic compression methods were applied (average 2 hours) in both groups of patients. Evaluation of radial arterial arterial blood flow by colour Doppler study was done on next day after the procedure in both groups. Results of this study in which RAO was determined by vascular doppler study showed that frequency of radial artery occlusion were 13.5% one day after transradial coronary procedures. We found the incidence was 8.8% vs. 18.4%, (p=0.04) in Group I and Group II respectively. The incidence of RAO was significantly lower in post procedural nitroglycerine group. From multivariate logistic regression analysis diabetes mellitus (p = 0.02), hemostatic compression time for more than 02 hours after sheath removal (p = <0.001) and procedure time (p = 0.02) was predictors of RAO. So, the administration of nitroglycerin at the end of a transradial catheterization reduced the incidence of RAO, as shown by 1 day after the radial procedure by doppler ultrasound.


Subject(s)
Arterial Occlusive Diseases , Percutaneous Coronary Intervention , Humans , Nitroglycerin/therapeutic use , Radial Artery/diagnostic imaging , Percutaneous Coronary Intervention/adverse effects , Cardiac Catheterization/methods , Bangladesh , Ultrasonography, Doppler/adverse effects , Ultrasonography, Doppler/methods , Arterial Occlusive Diseases/etiology , Arterial Occlusive Diseases/prevention & control , Arterial Occlusive Diseases/epidemiology
6.
J Basic Clin Physiol Pharmacol ; 34(1): 11-20, 2023 Jan 01.
Article in English | MEDLINE | ID: mdl-36117247

ABSTRACT

Liver and heart are anatomically and patho-physiologically related. In heart failure (HF) the increased right atrial pressure and volume overload cause histological changes in hepatocytes, leading to a condition known as "congestive hepatopathy" (CH), with consequent variations in liver functioning and ultrasound (US) findings. CH has specifical US findings especially regarding venous vessels aspect, easily detecting by gray-scale study, but many others can be distinguished by Doppler analysis. Usually, hepatic veins look enlarged and hypocollassing, together with signs of portal hypertension (hepatomegaly, ascites, splenomegaly, porto-systemic collaterals). Typically, in CH Doppler findings regard alterations in venous vessel flow and arterial resistance (venous system hyperpulsatility, reduced velocity flow, high resistance index in hepatic arterial Doppler spectrum). Sometimes CH and other primary hepatopathy can coexist, and therefore some of the expected variations may not manifest: it allows suspecting an unknown underlying liver disease. At last, US technologies of more recent applications, even if not routinely used, allow investigating additional aspects such as elastography that detects changes in liver elasticity or contrastographic US, able to show differences in hepatic venous opacification. However, most of these US signs are not pathognomonic, and therefore a multidisciplinary clinical reasoning must not be lacking. The aim of the present review is to easily provide US signs of liver alterations in HF, in particular right heart failure with volume overload, suggesting including liver US in instrumental diagnosis and therapeutic monitoring of HF.


Subject(s)
Heart Failure , Liver Diseases , Humans , Liver/diagnostic imaging , Liver/pathology , Liver Diseases/diagnostic imaging , Liver Diseases/etiology , Hepatic Artery/diagnostic imaging , Hepatic Artery/pathology , Heart Failure/diagnostic imaging , Ultrasonography, Doppler/adverse effects
7.
Acta Med Port ; 36(4): 246-253, 2023 Apr 03.
Article in English | MEDLINE | ID: mdl-36240233

ABSTRACT

INTRODUCTION: Parathyroid adenoma is the most frequent cause of primary hyperparathyroidism. In recent years, the preoperative location of parathyroid adenomas allowed minimally invasive surgical techniques that have become preferred over the traditional bilateral neck exploration. The more recent guidelines on this subject highlight the role of nuclear medicine imaging tests. The aim of this study was to review the current role of Doppler ultrasound (US) in assessing the preoperative location of parathyroid adenomas in patients with primary hyperparathyroidism. MATERIAL AND METHODS: Retrospective study based on data from patients with primary hyperparathyroidism that underwent parathyroidectomy between January 2013 and January 2022 at the Centro Hospitalar Universitário Lisboa Central. Statistical analysis was performed with IBM SPSS Statistics, version 26.0.0.0®. RESULTS: Parathyroidectomy was performed in 171 patients (77.8% females) with primary hyperparathyroidism. Cervical Doppler ultrasound was the most performed test (64.3%, n = 110) for preoperative location and detected a suspicious lesion in 98 patients (89.1%). The preoperative location of the parathyroid adenomas was assessed through the Doppler ultrasound and was compared with the surgical reports and histological findings; a correct identification was made in 76 patients (77.6%). Doppler ultrasound slightly underestimated the mean adenoma size (18.1 ± 7.7 mm preoperative versus 22 ± 8.4 mm postoperative). Calcium, parathyroid hormone levels, adenoma size and concomitant presence of thyroid nodules did not affect the accuracy of Doppler ultrasound. CONCLUSION: Doppler ultrasound showed high diagnostic accuracy even in patients with nodular thyroid disease regardless of calcium and parathyroid hormone levels and adenoma size. Furthermore, its safety, affordability and availability should favor its use as first line test in primary hyperparathyroidism to assess the preoperative location of parathyroid adenomas.


Subject(s)
Adenoma , Hyperparathyroidism, Primary , Parathyroid Neoplasms , Female , Humans , Male , Parathyroid Neoplasms/complications , Parathyroid Neoplasms/diagnostic imaging , Parathyroid Neoplasms/surgery , Hyperparathyroidism, Primary/diagnostic imaging , Hyperparathyroidism, Primary/etiology , Hyperparathyroidism, Primary/surgery , Calcium , Retrospective Studies , Parathyroid Hormone , Adenoma/complications , Adenoma/diagnostic imaging , Adenoma/surgery , Ultrasonography, Doppler/adverse effects
8.
Neurol Sci ; 33(2): 445-8, 2012 Apr.
Article in English | MEDLINE | ID: mdl-21927883

ABSTRACT

Neurotoxicity caused by intraarterial injection of low-dose low osmolar, iodinated contrast agents during radiologic studies is an extremely rare adverse event. Contrast medium induced disruption of the blood-brain barrier and a direct neurotoxic effect by contrast media have been proposed as a potential mechanism of neurotoxicity. This report describes an unusual case of transient neurotoxicity following diagnostic angiography mimicking clinically and radiologically subarachnoid hemorrhage. The patient recovered without any intervention after 4 days of conservative treatment.


Subject(s)
Cerebral Angiography/adverse effects , Contrast Media/adverse effects , Neurotoxicity Syndromes/etiology , Subarachnoid Hemorrhage/physiopathology , Aged , Female , Humans , Ischemic Attack, Transient/diagnosis , Neurotoxicity Syndromes/diagnosis , Tomography, X-Ray Computed , Ultrasonography, Doppler/adverse effects
9.
Harefuah ; 151(3): 146-9, 190, 2012 Mar.
Article in Hebrew | MEDLINE | ID: mdl-22519261

ABSTRACT

OBJECTIVE: The goal was to examine the knowledge of ultrasound end users regarding safety of ultrasound in pregnancy, and to compare it to ultrasound end users in the United States. METHODS: A questionnaire was distributed to ultrasound users at obstetrics and gynecology conventions and wards throughout the country, between the years 2008-2010, and compared to an identical questionnaire distributed in the United States. RESULTS: A total of 143 end users completed the questionnaire; 92% of them are physicians, 71% gynecologists; 3.5% routinely perform Doppler ultrasound in the first trimester. Overall, 36% of the ultrasound end users thought that the number of ultrasounds performed in low-risk pregnancy should be limited. Although 44.1% were familiar with the term thermal index, only 22.4% answered the related question correctly; 26.6% were familiar with the term mechanical index, but only 4.9% described it correctly. More than 80% of the end users did not know where to find the acoustic indices while performing the examination. No significant difference in knowledge was found between the ultrasound end users in Israel and the United States. CONCLUSIONS: The poor level of knowledge regarding safety issues, found both in Israel and United States, raises the necessity to reexamine the methods of informing the relevant audience on the courses and training programs available on these matters.


Subject(s)
Health Knowledge, Attitudes, Practice , Ultrasonography, Doppler/adverse effects , Ultrasonography, Prenatal/adverse effects , Adult , Aged , Female , Humans , Israel , Male , Middle Aged , Pregnancy , Pregnancy Trimester, First , Surveys and Questionnaires , United States
10.
Iran J Kidney Dis ; 16(5): 284-291, 2022 09.
Article in English | MEDLINE | ID: mdl-36178862

ABSTRACT

INTRODUCTION: Early diagnosis of diabetic nephropathy (DN), the leading cause of death in diabetic patients, is an important issue in preventing and reducing the disease burden for patients and the healthcare system. In this study, we aimed at investigating the value of color doppler ultrasonography in the diagnosis of early diabetic nephropathy (DN). METHODS: Two hundred and thirty-eight diabetic patients, were enrolled in this study and were categorized into, either control (n = 109) or study group (n = 129), according to 24 hours urinary albumin excretion rate (UAER), from January 2015 to March 2021. The morphologic findings of the kidneys were observed and compared, in both groups, by color doppler ultrasound technique, and blood flow of renal arteries was also measured, at all levels. Fasting plasma glucose (FPG), uric acid, homocysteine, beta-2- microglobulin, cystatin C, hemoglobin A1c (HbA1c) and CRP were also extracted from their laboratory results. RESULTS: Compared to the control group, the study group had lower intrarenal arterial end-diastolic blood flow velocity (EDV) and higher arterial resistance index (RI) (P ~ < .05). A significant diagnostic value of intrarenal arterial EDV and RI was found for early detection of DN (P ~ < .05). Intrarenal arterial RI and EDV showed positive correlations with UAER, FPG, uric acid, homocysteine, beta-2-microglobulin, cystatin C, HbA1c, and CRP (P ~ < .05). CONCLUSION: Color doppler ultrasound markers of renal and intrarenal arteries has a high diagnostic value for DN at its early stage.  DOI: 10.52547/ijkd.7246.


Subject(s)
Diabetes Mellitus , Diabetic Nephropathies , Albumins , Blood Glucose , Cystatin C , Glycated Hemoglobin , Homocysteine , Humans , Ultrasonography, Doppler/adverse effects , Ultrasonography, Doppler, Color/adverse effects , Uric Acid
11.
J Cosmet Dermatol ; 21(12): 6717-6726, 2022 Dec.
Article in English | MEDLINE | ID: mdl-36066329

ABSTRACT

PURPOSE: Hyaluronic acid (HA) injection is a popular nonsurgical, rejuvenating procedure to treat glabellar frown lines, which has devastating complications such as blindness and skin necrosis due to the arterial occlusion of supratrochlear artery (STA). Therefore, when injecting into the frown lines, knowledge of the STA's depth and plane is necessary to prevent possible adverse events. The aim of this study was to identify the depths of STA in the area of the frown lines in order to maximize safety during filler injections. METHODS: Supratrochlear artery depth measurements were performed at the level of eyebrow and at the level of 1.5 cm above the eyebrow. Superficial duplex Doppler ultrasonography was performed of 71 cases. RESULTS: In the eyebrow level, the epidermis-artery distance (EAD) is between 1,8 and 5.9 mm, and the artery-periost distance (APD) is between 0.7 and 3.7 mm. In the 1.5 cm superior level of the eyebrow, the EAD is between 1.8 and 5.1 mm and the APD is between 0.6 and 3.8 mm. There was no significant difference between the depth measurements of the right and left STA. At the eyebrow level, APD is greater in men than in women. As the body mass index increases, the EAD and APD depth increases. EAD depth increases with increasing age. CONCLUSIONS: Based on the findings of this study, safe filler injections to correct the glabellar frown lines can be possible with intradermal injections just below the ryhtide. In the glabellar region, subcutaneous and supraperiosteal injections seems to be risky.


Subject(s)
Forehead , Ophthalmic Artery , Male , Humans , Female , Forehead/blood supply , Ophthalmic Artery/diagnostic imaging , Injections/adverse effects , Blindness/etiology , Ultrasonography, Doppler/adverse effects
12.
Int J Impot Res ; 34(6): 603-609, 2022 Sep.
Article in English | MEDLINE | ID: mdl-34389802

ABSTRACT

Men with Stuttering Priapism (SP) and sleep-related painful erections (SRPE) experience bothersome nocturnal painful erections resulting in poor sleep. The aim of this study is to observe common features and differences between men with SP and SRPE based on polysomnography, nocturnal penile tumescence (NPT), and penile doppler ultrasound (PDU). This is a prospective cohort study of 20 participants divided into two groups (Group 1 = SP [n = 12]; Group 2 = SRPE [n = 8]) with bothersome painful nocturnal erections. All participants were referred to the sleep disorder clinic to be assessed and consented for overnight polysomnography with simultaneous NPT recording and to complete validated sleep, sexual dysfunction and health-related quality of life questionnaires. Unstimulated PDU was also performed. Abnormal Polysomnographic findings (reduced sleep efficiency, total sleep time, and awake after sleep onset) were identified in both groups suggesting poor sleep. Men with SP had significantly longer erections (60.0 vs 18.5; p = 0.002) and took longer to detumesce once awake (25.7 vs 5.4 min; p = 0.001) than men with SRPE. They also had significantly higher peak systolic and end diastolic velocities on unstimulated PDU with an abnormal low resistance waveform identified. No sleep pathology was identified in men with SP. This implies a local (penile) etiology in men with SP. Men with SRPE had a normal resting PDU and abnormal sleep architecture with REM awakenings and significantly more Periodic limb movements (p = 0.04) than men with SP suggesting a central (sleep-related) cause in men with SRPE. Sexual dysfunction and poor HR-QoL was identified on validated questionnaires in both groups. SP and SRPE are rare entities that share similar symptoms (painful nocturnal erections and poor sleep) but dissimilar features of nocturnal erection onset, duration and resolution with different polysomnographic features which may allude to a different pathophysiology.


Subject(s)
Priapism , REM Sleep Parasomnias , Stuttering , Humans , Male , Pain/complications , Penile Erection/physiology , Priapism/complications , Priapism/diagnostic imaging , Prospective Studies , Quality of Life , REM Sleep Parasomnias/complications , Stuttering/complications , Ultrasonography, Doppler/adverse effects
13.
Int J Impot Res ; 34(5): 452-455, 2022 Aug.
Article in English | MEDLINE | ID: mdl-33981011

ABSTRACT

Peyronie's disease results in curvature of the penis which may cause difficulty with penetrative intercourse. The diagnosis of Peyronie's disease is easily obtained through history and physical examination alone, but the severity of erectile dysfunction relies on patient history and use of validated questionnaires. However, erectile dysfunction questionnaires were not validated in the Peyronie's disease population and may not be a reliable assessment. Penile Doppler ultrasound is a noninvasive tool that assesses vascular function. We hypothesized that penile Doppler ultrasound will be discordant with International Index of Erectile Function (IIEF) results in men with Peyronie's disease and erectile dysfunction. In this cross-sectional study, we reviewed a prospectively collected database of men with Peyronie's disease. In total, 108 men had questionnaire and ultrasound data. Of them, 87 had erectile dysfunction based on IIEF-EF or IIEF-5 (SHIM). However, 48 (55%) of those men had normal vascular parameters. Interestingly, among a subgroup of 33 men with severe erectile dysfunction on IIEF-EF or IIEF-5, 20 (61%) had normal vascular parameters. Our study demonstrates significant discordance between questionnaires and penile Doppler ultrasound. Therefore, ultrasound may be a useful tool in the workup of men with Peyronie's disease and erectile dysfunction.


Subject(s)
Erectile Dysfunction , Penile Induration , Cross-Sectional Studies , Erectile Dysfunction/etiology , Humans , Male , Penile Induration/complications , Penile Induration/diagnostic imaging , Penis , Surveys and Questionnaires , Ultrasonography, Doppler/adverse effects
14.
Neurosurgery ; 91(1): 115-122, 2022 07 01.
Article in English | MEDLINE | ID: mdl-35383697

ABSTRACT

BACKGROUND: Venous thromboembolism (VTE), encompassing deep venous thrombosis (DVT) and pulmonary embolism (PE), causes postoperative morbidity and mortality in neurosurgical patients. The use of pharmacological prophylaxis for DVT prevention in the immediate postoperative period carries increased risk of intracranial hemorrhage, especially after skull base surgeries. OBJECTIVE: To investigate the impact of routine Doppler ultrasound monitoring in prevention and tiered management of VTE after skull base surgery. METHODS: We retrospectively analyzed a large cohort of consecutive adult patients who were prospectively and uniformly managed with routine monitoring by Doppler ultrasound for DVT after resection of a skull base tumor. RESULTS: A total of 389 patients who underwent 459 surgeries for intracranial tumor resection were analyzed. Skull base meningioma was the most common pathology. Forty-four (9.59%) postoperative VTEs were detected: 9 (1.96%) with PE with or without DVT and 35 (7.63%) with DVT alone. Four cases of subsegmental PE were diagnosed without evidence of lower extremity DVT, possibly in the setting of peripherally inserted central catheters maintenance. One patient had a preoperative proximal DVT and underwent a prophylactic inferior vena cava filter but expired from PE after discharge. Prior history of VTE (risk ratio [RR] 5.13; 95% CI 2.76-7.18; P < .01), anesthesia duration (RR 1.14; 95% CI 1.03-1.27; P = .02), and blood transfusion (RR 1.95; 95% CI 1.01-3.37; P = .04) were associated with VTE development on multivariate analysis. CONCLUSION: Routine postoperative venous ultrasound monitoring detects asymptomatic DVT guiding management. This is an alternative strategy to prescribing pharmacological VTE prophylaxis immediately after lengthy surgeries for intracranial tumors. Peripherally inserted central catheters were associated with subsegmental PE.


Subject(s)
Pulmonary Embolism , Venous Thromboembolism , Venous Thrombosis , Adult , Anticoagulants/therapeutic use , Humans , Incidence , Postoperative Complications/diagnostic imaging , Pulmonary Embolism/complications , Pulmonary Embolism/prevention & control , Retrospective Studies , Risk Factors , Skull Base , Ultrasonography, Doppler/adverse effects , Venous Thromboembolism/etiology , Venous Thrombosis/diagnostic imaging , Venous Thrombosis/drug therapy , Venous Thrombosis/etiology
15.
Curr Opin Anaesthesiol ; 24(2): 171-6, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21293263

ABSTRACT

PURPOSE OF REVIEW: To determine whether sufficient evidence exists to justify routine use of oesophageal Doppler monitoring to guide perioperative haemodynamic management in high-risk surgery. RECENT FINDINGS: Systematic reviews of the literature have been performed independently by the National Health Service Centre for Evidence-based Purchasing in the UK, and the US Agency for Healthcare-Related Quality. A before-after evaluation was also recently performed in three hospitals by the National Health Service Technology Adoption Centre. Although multicentre prospective randomized controlled trials are lacking, the evidence base for both outcome-benefit and cost-benefit is considered strong enough by the National Institute for Health and Clinical Excellence in the UK for them to recommend use of this technology in high-risk surgical patients. Whether these findings also apply to other monitoring technologies requires formal validation. SUMMARY: Better patient outcomes can be achieved by perioperative haemodynamic optimization using oesophageal Doppler monitoring and should be considered for routine use in most types of high-risk surgery.


Subject(s)
Echocardiography, Transesophageal/standards , Esophagus/diagnostic imaging , Monitoring, Intraoperative/standards , Ultrasonography, Doppler/standards , Cardiac Output/physiology , Echocardiography, Transesophageal/adverse effects , Goals , Hemodynamics/physiology , Humans , Perioperative Care , Risk , Ultrasonography, Doppler/adverse effects , United States , United States Agency for Healthcare Research and Quality
16.
Harefuah ; 150(7): 588-92, 617, 616, 2011 Jul.
Article in Hebrew | MEDLINE | ID: mdl-21874769

ABSTRACT

As a form of energy, diagnostic ultrasound (DUS) has the potential to have effects on Living tissues, e.g. bioeffects. The two most likely mechanisms for bioeffects are heating and cavitation. Hyperthermia is considered teratogenic in human fetuses during the first trimester Actual temperature changes cannot be studied in the human fetus. The thermal index [TI) expresses the potential for rise in temperature at the ultrasound's focal point. The mechanical index (MI) indicates the potential for the ultrasound to induce inertial cavitation in tissues. Nevertheless, cavitation has not been documented in mammalian fetuses, since there is not an air-water interface, which is needed for the cavitation mechanism. Since an output of TI over 1.5 is a known hazard, the question is: What are the settings in which such hazardous exposure occurs? Our conclusions regarding safety of DUS, based on the data that has been available till now, are the following: (1) Ultrasound end-users are poorly informed regarding safety issues during pregnancy. Further efforts in the realm of education and training are needed in order to improve knowledge of end-users about the acoustic output of the machines and safety issues. (2) First trimester ultrasound is associated with negligible rise in the thermal index. (3) Increased acoustic output Levels, as expressed by TI levels, are reached while performing obstetrical Doppler studies. In particular, TI Levels may reach 1.5 and above. Doppler procedures should be performed with caution and should be as brief as possible during obstetrical ultrasound. (4) Acoustic exposure levels during 3D/4D ultrasound examination, as expressed by TI are comparable to the two-dimensional B-mode ultrasound.


Subject(s)
Acoustics , Ultrasonography, Doppler/methods , Ultrasonography, Prenatal/methods , Female , Fetus , Humans , Pregnancy , Pregnancy Trimester, First , Ultrasonography, Doppler/adverse effects , Ultrasonography, Prenatal/adverse effects
17.
Arch Dis Child Fetal Neonatal Ed ; 106(1): 96-103, 2021 Jan.
Article in English | MEDLINE | ID: mdl-32398270

ABSTRACT

Necrotising enterocolitis (NEC) is a serious inflammatory bowel disease of prematurity with potentially devastating complications and remains a leading cause of morbidity and mortality among premature infants. In recent years, there has been accumulating data regarding benefits of using bowel ultrasound (BUS) in the diagnosis and management of NEC. Despite this, adoption of robust BUS programmes into clinical practice has been slow. As BUS is a relatively new technique, many barriers to implementation exist, namely lack of education and training for sonographers and radiologists, low case volume and unfamiliarity by clinicians regarding how to use the information provided. The aim of this manuscript is to provide a framework and a roadmap for units to implement BUS in day-to-day practice for NEC diagnosis and management.


Subject(s)
Enterocolitis, Necrotizing/diagnostic imaging , Infant, Newborn, Diseases/diagnostic imaging , Ultrasonography, Doppler/methods , Early Diagnosis , Enterocolitis, Necrotizing/diagnosis , Humans , Infant, Newborn , Infant, Newborn, Diseases/diagnosis , Ultrasonography, Doppler/adverse effects
18.
Prenat Diagn ; 29(13): 1204-12, 2009 Dec.
Article in English | MEDLINE | ID: mdl-19899071

ABSTRACT

Ultrasound is a commonly employed imaging modality in obstetrics and is generally regarded as safe to the fetus. Current ultrasound technology, however, has significantly higher output potential than older machines used in most clinical studies, and the safety profile for the increasing use of Doppler, 3-dimensional (D) and 4-D ultrasound with modern machines is unknown. This article reviews the current status of ultrasound safety within obstetrics, including proposed mechanisms of harm, existing scientific and clinical evidence regarding those mechanisms, and considerations of safety for the clinical user.


Subject(s)
Ultrasonography, Prenatal/adverse effects , Animals , Clinical Trials as Topic , Female , Hot Temperature/adverse effects , Humans , Pregnancy , Stress, Mechanical , Ultrasonography, Doppler/adverse effects , Ultrasonography, Prenatal/standards
19.
Eur J Obstet Gynecol Reprod Biol ; 233: 93-97, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30580230

ABSTRACT

OBJECTIVE: Congenital heart defects are the most common major structural fetal abnormalities. Color flow mapping has played a dominant role in the detection of abnormalities during the first trimester, regardless of the International Society of Ultrasound in Obstetrics and Gynecology warning on the use of Doppler during early pregnancy. The aim of our study was to investigate the use of transvaginal two-dimensional sonography without Doppler for assessing the four-chamber view and the outflow tract view of fetuses at 11-13 weeks of gestation for cardiac screening of major congenital heart defects. STUDY DESIGN: This was a prospective observational study conducted in the Fetal Medicine Unit of Cabueñes University Hospital, between May 2014 and August 2015. Only low risk-pregnancies were studied. All ultrasonographic examinations were performed by two experienced sonographers in maternal-fetal medicine. The combination of high-frequency transvaginal (nine MHz) and transabdominal (six MHz) ultrasonography transducers were used. An early cardiac screening was performed in 97% of cases. Statistical analysis was carried out using successive multivariate logistic regression models in order to investigate the effect of crown-rump length and body mass index on the probability of visualizing the four-chamber view and/or the outflow tract view. RESULTS: 663 low-risk pregnant women were included. Regarding the transvaginal approach, neither the crown-rump length nor the body mass index had a statistically significant relationship on the probability of visualization of the four-chamber view and outflow tract view. For the transabdominal approach, the crown-rump length and the body mass index presented a statistically significant effect on the visualization of the four-chamber view and the outflow tract view. Using the transvaginal approach: the success rate of performing a four-chamber view was 89.4% and 82.4% for the outflow tract view. Using the transabdominal approach: the success rate of performing a four-chamber view was 77.8% and 61.5% for the outflow tract view. Four major congenital heart defects were diagnosed, and the prenatal ultrasonagraphic diagnosis was confirmed for all cases. CONCLUSIONS: Routine first-trimester ultrasonagraphy without Doppler, when performed by experienced sonographers, can effectively identify major congenital heart defects. Additional multicenter well designed studies should clarify the feasibility of this approach.


Subject(s)
Fetal Heart/diagnostic imaging , Heart Defects, Congenital/diagnostic imaging , Ultrasonography, Prenatal/methods , Adult , Female , Humans , Logistic Models , Pregnancy , Pregnancy Trimester, First , Prospective Studies , Ultrasonography, Doppler/adverse effects
20.
Med Ultrason ; 20(3): 379-384, 2018 Aug 30.
Article in English | MEDLINE | ID: mdl-30167593

ABSTRACT

The comet tail artefact is probably one of the most commonly and imprecisely used to describe vertical artefacts found in lung ultrasound. Two distinct artefacts are commonly observed: the lung comets and the B-lines. Both artefacts differ with regard to generation mechanism and clinical significance. This review explores the current understanding and use of these two artefacts in lung ultrasound and suggests how to avoid the pitfalls related to confusing comet tail artefacts with other vertical artefacts.


Subject(s)
Artifacts , Lung Diseases/diagnostic imaging , Lung/diagnostic imaging , Ultrasonography, Doppler/methods , Female , Germany , Humans , Male , Risk Factors , Sensitivity and Specificity , Ultrasonography, Doppler/adverse effects
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