The causes of nail apparatus pigmentation presenting to a melanoma screening clinic a prospective study.

BACKGROUND: Advanced stage primary cutaneous malignant melanoma (PCMM) has a high mortality. PCMM may affect any area of the skin, including the nail apparatus (malignant melanoma or subungual melanoma). Although nail apparatus malignant melanoma (NAMM) is rare, delayed diagnosis carries a poor prognosis. AIM: The primary aim was to study the range of nail presentations and identify key patterns to aid in differential diagnosis. A secondary aim was to quantify the number of patients requiring surgery, indications for biopsy, and the incidence and characteristics of NAMM. METHODS: This was a prospective study of all referrals with nail apparatus pigmentation to a weekly dedicated melanoma screening clinic over a 6-month period. RESULTS: In total, 2246 patients were included. Of the 38 patients referred with nail pigmentation, 1 (2.6%) was diagnosed with NAMM and involved a fungating amelanotic lesion of the right hallux. The remaining patients were diagnosed with subungual haematoma (20/38; 52.6%), viral wart (2/38; 5.4%), acral fibrokeratoma (1/38; 2.6%), myxoid cyst (3/38; 7.9%), fungal nail infection (4/38; 10.5%), Pseudomonas nail infection (1/38; 2.6%), benign linear pigmentation (2/38, 5.3%), Bowen disease (1/38, 2.6%), psoriatic nail changes (2/38; 5.3%) and matrix malalignment (1/38; 2.6%). Of the eight patients (21.1%) who required surgery, five had a biopsy taken and three underwent surgery. Only 14 cases were followed up by Dermatology. NAMM accounted for 0.7% of all melanomas diagnosed. CONCLUSION: We illustrate the wide range of diagnoses for pigmented nail presentations and highlight the late presentation of advanced disease in a patient presenting with NAMM.

[Rebound tonometry with sterilized probes]. / Rebound-Tonometrie mit sterilisierten Sonden.

BACKGROUND: Intraoperative measurement of intraocular pressure (IOP) opens up possibilities to investigate the influence of IOP on the stability of the eyeball during the performance of surgical maneuvers. Few techniques have been described, none of which are commercially available. This study investigated the use of sterilized probes for rebound tonometry, which could be used intraoperatively. MATERIAL AND METHODS: Tonometry was performed on 30 eyes using a noncontact tonometer and rebound tonometry with the iCare 100 and iCare 200 (iCare Finland Oy, Vantaa, Finland) in a sitting and in a supine position. When performing rebound tonometry probes from the package were used sequentially with sterilized probes. The comparability of sterilized and nonsterilized probes was investigated using different rebound tonometers and different settings. RESULTS: Measurements on a sitting subject were comparable with sterilized and nonsterilized probes. Statistically significant comparability was also found in a supine position. Measurements with identically sterilized probes on identically positioned subjects were comparable with iCare 100 und iCare 200 (T2 vs. T4, p = 0.003 und T3 vs. T5 p < 0.001). The comparison of measurements of the original probe with the sterilized probe in a sitting and in a supine position were possible with statistical significance (p < 0.005). Measuring with the iCare 200 in a sitting position showed a slightly lower IOP with the sterilized probe with the difference being statistically significant. DISCUSSION: Single autoclaving does not alter the probes' ability to measure IOP. CONCLUSION: The use of probes which have been sterilized according to the regulations for other surgical instruments opens up new possibilities for the intraoperative measurement of IOP. This facilitates the use in scientific studies on surgical techniques. In the postoperative period the use of sterilized probes can reduce the risk of infection.

The use of MTA in the modern management of teeth affected by dens invaginatus.

Dens invaginatus is a dental anomaly that can result in loss of tooth vitality and the need for root canal treatment. The pulpal morphology of these teeth can be complex which makes successful root canal treatment difficult to achieve. To maintain vitality attempts have been made to prophylactically treat these teeth by sealing the invagination with a variety of materials. This paper describes the use of mineral trioxide aggregate (MTA) in both the prophylactic treatment of teeth with minor invaginations and the incorporation of MTA in the final obturation of non-vital teeth with invaginations with grossly atypical morphology.

Bronchiolitis obliterans organizing pneumonia associated with Pneumocystis jiroveci infection in orthotopic liver transplantation.

We report a patient who presented 6 months after orthotopic liver transplantation (OLT) with fever, dyspnea, and pulmonary infiltrates with biopsy-confirmed Pneumocystis jiroveci infection associated with a process of bronchiolitis obliterans organizing pneumonia (BOOP). We present this second case of BOOP associated with P. carinii pneumonia after OLT to highlight the risk of such disease combination in all transplant patients as well as discuss the protective effect of post-transplant prednisolone with trimethoprim-sulfamethoxazole prophylaxis and the possible duration of prophylaxis.

Dens invaginatus. Part 1: classification, prevalence and aetiology.

AIM: To review and discuss the aetiology, prevalence and classification of this dental anomaly together with the morphology of an invagination and the most appropriate nomenclature. SUMMARY: This review considers the different possible nomenclatures and concludes that dens invaginatus is the most appropriate description. The paper highlights the different reported prevalence figures and concludes that the problem is probably one of the most common of the dental developmental abnormalities with maxillary lateral incisors most commonly affected. The paper suggests that the classification system described by Oehlers (1957a) is probably the most clinically relevant and that the morphological features associated with this problem may increase the risk of pulpal pathology developing and complicate any possible endodontic treatment. KEY LEARNING POINTS: * The aetiology of dens invaginatus is still unknown, although there is some evidence that it may be genetic in origin. * The problem is probably more prevalent than most clinicians are aware of and this is because of the diagnostic difficulties associated with the anomaly. * The nature of the problem may increase the risk of pulp disease and complicate any root canal treatment.

Dens invaginatus. Part 2: clinical, radiographic features and management options.

AIM: To describe the possible clinical and radiographic features of this developmental anomaly, review previous treatment recommendations and suggest management options based on the classification of the problem. SUMMARY: This paper describes the clinical and radiographic features related to the different types of dens invaginatus and highlights those features which may indicate the presence of a previously undetected invagination. Aids to clinical diagnosis are described together with a description of the possible radiographic features, which may suggest the presence of an invagination. Previous treatment suggestions are described and suggestions as to possible management options, based on current endodontic knowledge and the classification of the problems are described. KEY LEARNING POINTS: * Thorough clinical and radiographic examination is required to diagnose and successfully treat minor to severe invaginations. * Modern clinical techniques may facilitate the management of invaginations once considered untreatable.

Clinical applications of polytetrafluoroethylene (PTFE) tape in restorative dentistry.

Restorative dental procedures are ever developing; one reason for this can be attributed to newer materials with better handling properties and our ability to manipulate them more effectively. As a result various techniques have been described to aid clinicians in obtaining predictable results in restorative dental procedures. This article aims to review the use of plumber's tape to assist in adhesive, endodontic and implant related dental procedures, when compared to other available materials.

An analysis of inpatient dermatologic consultations at University Hospital Limerick: inadequate infrastructure leads to acute skin failure.

BACKGROUND: Approximately 15-20 % of the general population have skin diseases and it is therefore clear that inpatients can also present with various skin conditions that require dermatology input and in some cases the primary reason for admission to hospital. Inpatient hospital care is more expensive than outpatient care. Recent trends are moving towards outpatient care, as there is huge pressure on hospital bed availability. AIMS: The main aim of this study was to analyse patients referred with dermatological complaints and how soon after admission, were patients assessed by the dermatology team. Most dermatologic work is outpatient based and inpatient workload can be underestimated. METHODS: We retrospectively reviewed our inpatient consultations with a total of 220 consultations (males 113, females 107) between August 2014 and April 2015, to document this significant area of work over an eight-month period. RESULTS: The services requesting consultations were mostly general medicine 45.9 % (101/220), surgery 25.4 % (56/220) and paediatrics 24 % (53/220). Dermatologist's diagnosis was different from the referral team diagnosis in 60 % (132/220) of consults, with prompt inpatient assessment by the dermatologist within 24 h of admission. Most common dermatoses diagnosed included eczema 21.8 % (48/220) and psoriasis 7.3 % (16/220). CONCLUSION: Timely diagnosis and inpatient care has important implications on appropriate treatment, duration of hospital stay and patient outcome.

Laparoscopic or open preperitoneal repair in the management of recurrent groin hernias.

Laparoscopic repair is considered by many to be the operation of choice for a recurrent hernia. The aim of this study was to compare long-term outcome of laparoscopic and open preperitoneal repair of recurrent groin hernias. All patients operated on by one surgeon for recurrent groin hernia between January 1994 and December 2001 were reviewed. Forty-five percent had their data collected prospectively, while in 55% the data was collected retrospectively. Over the study period 128 patients underwent repair of a recurrent groin hernia of whom 99 had either a laparoscopic or open preperitoneal repair. The mean age was 60 years (range 15-88), 93 were men while 6 were women. Forty-five had their hernia repaired laparoscopically while 54 had an open preperitoneal repair. Patients have been followed for a median of 5 years (range 2-9 years). There has been no recurrence in either group of patients. Two patients in the laparoscopic group and four in the open group suffered from chronic groin pain. One patient in either group developed a Hydrocele that was dealt with surgically. Laparoscopic and open preperitoneal repair of a recurrent groin hernia are associated with similar long-term outcomes.

Prospective study on the presentation and outcome of patients with an acute hernia.

Recent advances in hernia surgery should help to make operation more acceptable to patients and their doctors. The aim of this study was to prospectively assess the presentation and management of patients with an acute hernia in light of these changes. Data on all patients admitted with an acute hernia between March 2001 and February 2004 was entered on a prospective database. During the 3 year study period, of the 91 patients admitted with an acute hernia, 41 were ventral, 24 femoral, 24 inguinal and 2 parastomal. Forty-six had a previous medical assessment, 18 of these had been declared unfit for operation at that assessment; ten were ASA4 (ASA, American Society of Anaesthesiology), five ASA3 and three ASA2. Eleven patients were on the waiting list for operation, three of whom had a previous acute hospital admission. For 30 patients this hospital admission was the first indication that they had a hernia while the remaining were aware that they had a hernia but did not seek medical advice. Of the five patients who died, two while being assessed for operation and three postoperatively, three were ASA4 and had a ventral hernia while two were ASA3 with a femoral hernia. Despite advances in hernia surgery there is still room for improvement in preoperative assessment of patients presenting with an acute hernia.

Hernias are the most common cause of strangulation in patients presenting with small bowel obstruction.

BACKGROUND: Small bowel obstruction (SBO) is a leading cause of admission to surgical emergency units. Strangulation is associated with a 10-fold increase in mortality. The aim of the present study was to identify the most frequent causes of strangulation in patients presenting with small bowel obstruction. METHODS: A prospective study was conducted of all patients presenting with SBO in one teaching hospital between 2003 and 2004. RESULTS: One hundred and sixty-one patients with symptoms and signs of small bowel obstruction were admitted. Eighty-three were confirmed with contrast studies. The male:female ratio was 1:1.6. The aetiology of obstruction was adhesions in 97 patients (60.2%), hernia in 29 (18%), malignancy in 17 (10.6%) and miscellaneous causes in 18 (11.2%). Operative procedures were performed on 74 patients (46%), 31 of them (42%) with adhesions, 25 (34%) with hernias and 18 (24%) due to other causes. Strangulated bowel occurred in 15 patients (9.3%); 12 had hernias whilst three had adhesions (P < 0.0001). Of the strangulated hernias, ten were femoral, one was inguinal and one was paraumbilical. There were seven deaths; three occurred in patients declared unfit for surgery, while four occurred post-operatively - two had strangulated bowel, the other two had advanced cancer. CONCLUSION: Whilst adhesions are the most common cause of small bowel obstruction, hernias remain the most frequent cause of strangulation in patients presenting with this condition.