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1.
Ecotoxicology ; 33(7): 683-696, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-38861073

RESUMEN

Silver nanoparticles (AgNPs) are among the most produced nanomaterials in the world and are incorporated into several products due to their biocide and physicochemical properties. Since freshwater bodies are AgNPs main final sink, several consequences for biota are expected to occur. With the hypothesis that AgNPs can interact with environmental factors, we analyzed their ecotoxicity in combination with humic acids and algae. In addition to the specific AgNPs behavior in the media, we analyzed the mortality, growth, and phototactic behavior of Chydorus eurynotus (Cladocera) as response variables. While algae promoted Ag+ release, humic acids reduced it by adsorption, and their combination resulted in an intermediated Ag+ release. AgNPs affected C. eurynotus survival and growth, but algae and humic acids reduced AgNPs lethality, especially when combined. The humic acids mitigated AgNP effects in C. eurynotus growth, and both factors improved its phototactic behavior. It is essential to deepen the study of the isolated and combined influences of environmental factors on the ecotoxicity of nanoparticles to achieve accurate predictions under realistic exposure scenarios.


Asunto(s)
Cladóceros , Sustancias Húmicas , Nanopartículas del Metal , Plata , Contaminantes Químicos del Agua , Plata/toxicidad , Nanopartículas del Metal/toxicidad , Animales , Contaminantes Químicos del Agua/toxicidad , Cladóceros/efectos de los fármacos , Cladóceros/fisiología
2.
Toxicol Appl Pharmacol ; 471: 116560, 2023 07 15.
Artículo en Inglés | MEDLINE | ID: mdl-37230195

RESUMEN

The imminent increase in global food demand inevitably leads to an increase in agricultural practices, with an emphasis on pesticide applications. Nanotechnology-based pesticides, or nanopesticides, have gained importance as they are more efficient and, in some cases, less toxic than their conventional counterparts. However, concerns about these novel products have arisen as evidence about their (eco)safety is controversial. This review aims to: (1) introduce the currently applied nanotechnology-based pesticides and their mechanisms of toxic action; (2) describe their fate when released into the environment, with an emphasis on aquatic environments; (3) summarize available research on ecotoxicological studies in freshwater non-target organisms through a bibliometric analysis; and (4) identify gaps in knowledge from an ecotoxicological perspective. Our results show that the environmental fate of nanopesticides is poorly studied and depends on both intrinsic and external factors. There is also a need for comparative research into their ecotoxicity between conventional pesticide formulations and their nano-based counterparts. Among the few available studies, most considered fish species as test organisms, compared to algae and invertebrates. Overall, these new materials generate toxic effects on non-target organisms and threaten the integrity of the environment. Therefore, deepening the understanding of their ecotoxicity is crucial.


Asunto(s)
Plaguicidas , Contaminantes Químicos del Agua , Animales , Plaguicidas/toxicidad , Nanotecnología , Peces , Agricultura , Contaminantes Químicos del Agua/toxicidad
3.
Environ Sci Pollut Res Int ; 31(3): 3754-3762, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38091224

RESUMEN

Insecticides are widely used for pest control and frequently reach aquatic systems, imposing a risk to the biota. In this work, the effect of environmental concentrations of bifenthrin on the grazing capacity of Simocephalus vetulus (Cladocera) and Argyrodiaptomus falcifer (Copepoda) on phytoplankton was evaluated. Fifteen microcrustacean individuals and a natural phytoplankton assemblage dominated by Cyanobacteria were exposed during 46 h to three concentrations of bifenthrin (C0 0 µg L-1, C1 0.02 µg L-1, and C2 0.05 µg L-1). A significant decrease in both microcrustaceans grazing rates on total phytoplankton was observed in C2 compared to C0 and C1. The filtration rate (ml ind-1 h-1) of S. vetulus decreased significantly for the cyanobacteria Anabaenopsis arnoldii, Dolichospermum circinale, and Glaucospira sp. in C2 compared to C0 and C1. The ingestion rate (org ind-1 h-1) of A. falcifer decreased significantly in C1 and C2 compared to C0 only for A. arnoldii. Regarding phytoplankton morphological groups, the filtration rate of S. vetulus decreased in C1 and C2 compared to C0 for Colonies and Coenobiums in C2 concerning C0 and C1 for Filaments and in C2 compared to C0 for Silicified. For A. falcifer, the ingestion rate was reduced in C2 compared to C0 for Silicified, Flagellated, and Sessile. The results showed that bifenthrin affected both microcrustaceans grazing capacity on phytoplankton, especially at the highest insecticide concentration.


Asunto(s)
Cladóceros , Copépodos , Cianobacterias , Insecticidas , Piretrinas , Humanos , Animales , Fitoplancton , Zooplancton , Insecticidas/farmacología
4.
Sci Total Environ ; 912: 169240, 2024 Feb 20.
Artículo en Inglés | MEDLINE | ID: mdl-38072253

RESUMEN

Salinization of aquatic systems is predicted to increase due to climate and land use changes. Nevertheless, community responses may be different according to the ecosystem characteristics and contextual scenarios. Small flowing waters are particularly vulnerable to salinization, which may impact on the biodiversity and ecosystem processes, but this remains unclear. We conducted a study in 42 lowland streams characterized by overall high nutrient levels along a salinity gradient between 2 and 160 g L-1 to analyze changes in zooplankton structural and functional metrics, and the grazing effects of zooplankton on phytoplankton affecting the energy transfer. Generalized additive models revealed that the analyzed metrics were relatively influenced by salinity, with factors related to trophic conditions playing an important role as well. Total abundance and biomass decreased along the salinity gradient while increasing at intermediate soluble reactive phosphorous concentrations (SRP) in the former and with a linear increase in the SRP in the latter case. Taxonomic richness decreased with salinity and dissolved inorganic nitrogen, with species replacement toward saline-tolerant ones according to the compositional and optimums analyses. In opposite, functional richness did not display any specific trend within the environmental gradients. This explains why zooplankton compositional changes were not reflected into shifts in the grazing pattern on phytoplankton, which was in turn driven by SRP and dissolved oxygen concentrations. Further research is a critical requirement in these poorly studied ecosystems for planning mitigation actions to the co-occurrence of eutrophication and salinization in a fast changing world.


Asunto(s)
Ecosistema , Zooplancton , Animales , Zooplancton/fisiología , Ríos , Biodiversidad , Biomasa , Fitoplancton/fisiología , Nutrientes
5.
Cell Rep Med ; 5(5): 101569, 2024 May 21.
Artículo en Inglés | MEDLINE | ID: mdl-38744279

RESUMEN

Systemic lupus erythematosus (SLE) displays a hallmark interferon (IFN) signature. Yet, clinical trials targeting type I IFN (IFN-I) have shown variable efficacy, and blocking IFN-II failed to treat SLE. Here, we show that IFN type levels in SLE vary significantly across clinical and transcriptional endotypes. Whereas skin involvement correlated with IFN-I alone, systemic features like nephritis associated with co-elevation of IFN-I, IFN-II, and IFN-III, indicating additive IFN effects in severe SLE. Notably, while high IFN-II/-III levels without IFN-I had a limited effect on disease activity, IFN-II was linked to IFN-I-independent transcriptional profiles (e.g., OXPHOS and CD8+GZMH+ cells), and IFN-III enhanced IFN-induced gene expression when co-elevated with IFN-I. Moreover, dysregulated IFNs do not explain the IFN signature in 64% of patients or clinical manifestations including cytopenia, serositis, and anti-phospholipid syndrome, implying IFN-independent endotypes in SLE. This study sheds light on mechanisms underlying SLE heterogeneity and the variable response to IFN-targeted therapies in clinical trials.


Asunto(s)
Interferones , Lupus Eritematoso Sistémico , Humanos , Lupus Eritematoso Sistémico/genética , Lupus Eritematoso Sistémico/inmunología , Lupus Eritematoso Sistémico/patología , Interferones/metabolismo , Interferones/genética , Femenino , Adulto , Masculino , Transcriptoma/genética , Interferón Tipo I/metabolismo , Interferón Tipo I/genética , Persona de Mediana Edad , Transcripción Genética , Regulación de la Expresión Génica
6.
Aquat Toxicol ; 275: 107069, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-39241467

RESUMEN

The wide range of applications of nanomaterials (NM) in different fields has led to both uncontrolled production and release into environmental compartments, such as aquatic systems, where final disposal occurs. Some efforts have been made to estimate their concentrations in environmental matrices; however, little is known about the actual effects of environmental NM concentrations on biota. The aims of the present review are to (i) expose the state of the art of the most applied NM and their actual concentrations regarding how much is being released to the aquatic environment and which are the predicted ones; (ii) analyze the current literature to elucidate if the aforementioned conditions were proven to cause deleterious effects on the associated organisms; and (iii) identify gaps in the knowledge regarding whether the actual NM concentrations are harmful to aquatic biota. These novel materials are expected to being released into the environment in the range of hundreds to thousands of tons per year, with Si- and Ti-based NM being the two most important. The estimated environmental NM concentrations are in the low range of ng to µg/L, except for Ti-based ones, which concentrations reach values on the order of mg/L. Empirical information regarding the ecotoxicity of environmental NM concentrations mainly focused on metal-based NM, however, it resulted poor and unbalanced in terms of materials and test species. Given its high predicted environmental concentration in comparison with the others, the ecotoxicity of Ti-based NM has been well assessed in algae and fish, while little is known regarding other NM types. While only a few marine species were addressed, the freshwater species Daphnia magna and Danio rerio accounted for the majority of studies on invertebrate and fish groups, respectively. Most of the reported responses are related to oxidative stress. Overall, we consider that invertebrate groups are the most vulnerable, with emphasis on microcrustaceans, as environmentally realistic metal-based NM concentration even caused mortality in some species. In the case of fish, we assumed that environmental concentrations of Ti-based NM represent a growing concern and threat; however, further studies should be carried out by employing other kinds of NM. Furthermore, more ecotoxicological information is needed in the case of carbon-based NM, as they are expected to considerably increase in terms of released amounts and applications in the near future.


Asunto(s)
Organismos Acuáticos , Nanoestructuras , Contaminantes Químicos del Agua , Contaminantes Químicos del Agua/toxicidad , Nanoestructuras/toxicidad , Animales , Organismos Acuáticos/efectos de los fármacos , Metales/toxicidad , Ecotoxicología , Monitoreo del Ambiente
7.
medRxiv ; 2023 Aug 28.
Artículo en Inglés | MEDLINE | ID: mdl-37693590

RESUMEN

Interferons (IFN) are thought to be key players in systemic lupus erythematosus (SLE). The unique and interactive roles of the different IFN families in SLE pathogenesis, however, remain poorly understood. Using reporter cells engineered to precisely quantify IFN-I, IFN-II and IFN-III activity levels in serum/plasma, we found that while IFNs play essential role in SLE pathogenesis and disease activity, they are only significant in specific subsets of patients. Interestingly, whereas IFN-I is the main IFN that governs disease activity in SLE, clinical subsets are defined by the co-elevation of IFN-II and IFN-III. Thus, increased IFN-I alone was only associated with cutaneous lupus. In contrast, systemic features, such as nephritis, were linked to co-elevation of IFN-I plus IFN-II and IFN-III, implying a synergistic effect of IFNs in severe SLE. Intriguingly, while increased IFN-I levels were strongly associated with IFN-induced gene expression (93.5%), in up to 64% of cases, the IFN signature was not associated with IFN-I. Importantly, neither IFN-II nor IFN-III explained IFN-induced gene expression in patients with normal IFN-I levels, and not every feature in SLE was associated with elevated IFNs, suggesting IFN-independent subsets in SLE. Together, the data suggest that, unlike the IFN signature, direct quantification of bioactive IFNs can identify pathogenic and clinically relevant SLE subsets amenable for precise anti-IFN therapies. Since IFN-I is only elevated in a subset of SLE patients expressing the IFN signature, this study explains the heterogeneous response in clinical trials targeting IFN-I, where patients were selected based on IFN-induced gene expression rather than IFN-I levels.

8.
Environ Sci Pollut Res Int ; 30(10): 27137-27149, 2023 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-36378381

RESUMEN

Silver nanoparticles (AgNPs) are applied in diverse industries due to their biocide and physicochemical properties; therefore, they can be released into aquatic systems, interact with environmental factors, and ultimately exert adverse effects on the biota. We analyzed AgNPs effects on Ceriodaphnia reticulata (Cladocera) through mortality and life-history traits, considering the influence of food (Tetradesmus obliquus, Chlorophyceae) presence and concentration. C. reticulata was exposed to AgNPs in acute (absence and two algae concentrations plus five AgNPs treatments) and chronic assays (two algae concentrations plus three AgNPs treatments). AgNPs did not affect algae flocculation but increased Ag+ release, being these ions less toxic than AgNPs (as proved by the exposure to AgNO3). A reduction in AgNPs acute toxicity was observed when algae concentration increased. Acute AgNP exposure decreased C. reticulata body size and heart rate. The chronic AgNP exposure reduced C. reticulata molt number, growth, heart rate, and neonate size:number ratio, being these effects mitigated at the highest algae concentration. Increases in relative size and number of neonates were observed in AgNP treatments suggesting energy trade off. The increased Ag+ release with food presence suggests that the AgNP-algae interaction might be responsible of the decreased toxicity. Although algae reduced AgNP toxicity, they still exerted adverse effects on C. reticulata below predicted environmental concentrations. Since algae presence reduces AgNP effects but increases Ag+ release, studies should be continued to provide evidence on their toxicity to other organisms.


Asunto(s)
Chlorophyceae , Cladóceros , Nanopartículas del Metal , Animales , Humanos , Recién Nacido , Nanopartículas del Metal/toxicidad , Nanopartículas del Metal/química , Plata/toxicidad , Plata/química
9.
Environ Toxicol Pharmacol ; 102: 104238, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37524194

RESUMEN

Silica nanoparticles (SiNP) are the most produced nanomaterials due to their variety of applications. When released to environments, surface water bodies are their main final sink. SiNP toxicity is still inconclusive and may vary according to particle properties such as their size. We analyzed the size-related effects of SiNP (22 and 244 nm) on mortality, life history traits, and oxidative stress in the cladoceran Ceriodaphnia reticulata. The smaller SiNP (LC5072 h: 105.5 µg/ml) were more lethal than the larger ones (LC5072 h >500 µg/ml). The 22 nm-sized SiNP decreased the number of molts and neonates, increased superoxide dismutase and inhibited glutathione S-transferase activities, while larger SiNP did not exert substantial effects on the organisms at the tested concentrations. In conclusion, SiNP toxicity depended on their size, and this information should be considered for regulatory purposes and to the development of safe-by-design nanoproducts to ultimately guarantee the environment protection.


Asunto(s)
Cladóceros , Nanopartículas , Animales , Humanos , Recién Nacido , Nanopartículas/toxicidad , Estrés Oxidativo , Superóxido Dismutasa , Dióxido de Silicio/toxicidad
10.
Environ Sci Pollut Res Int ; 29(27): 41713-41724, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35098456

RESUMEN

Extreme climatic events are considered one of the main consequences of climate change. In the Pampas region, Argentina, an intensification of rainfall is expected during the periods of maximum agrochemical application. This study assesses the main factors determining the zooplankton community attributes in three streams belonging to the agricultural Pampas region, Argentina, and the effect of rainfall and seasonal crop practices on the zooplankton community composition. Sampling campaigns were performed before and after three rainfall events during two seasonal crop practices: (1) soybean chemical fallow-sowing and corn vegetative growth-flowering, (2) soybean vegetative growth-grain filling and corn sowing. The runoff in agricultural areas affected the zooplankton community attributes and composition. The biological oxygen demand, turbidity, and conductivity were the main water quality variables affecting the zooplankton community attributes. The increase of these variables after rainfall or during pre-emergence crop practices favoured the zooplankton groups most tolerant to eutrophication such as Bdelloidea, Chydoridae, Moinidae, and Sididae. Factors such as rainfall and seasonal crop practices must be considered in environmental monitoring design.


Asunto(s)
Agricultura , Zooplancton , Animales , Argentina , Monitoreo del Ambiente , Estaciones del Año
11.
JCI Insight ; 7(19)2022 10 10.
Artículo en Inglés | MEDLINE | ID: mdl-36040804

RESUMEN

The origin and mechanisms of autoantigen generation in systemic lupus erythematosus (SLE) are poorly understood. Here, we identified SLE neutrophils activated in vivo by IFN as a prominent source of Ro52, also known as tripartite motif-containing protein 21 (TRIM21), a critical autoantigen historically thought to be primarily generated by keratinocytes in SLE. Different from mononuclear cells and keratinocytes, SLE neutrophils are enriched in several unique Ro52 species containing a core sequence encoded by exon 4 (Ro52Ex4) in TRIM21. Ro52Ex4 is the main target of anti-Ro52 antibodies and is found in 2 Ro52 variants (Ro52α and a potentially novel isoform termed Ro52γ) upregulated in SLE neutrophils. Further analysis of Ro52γ revealed a subset of autoantibodies against a unique C-terminal domain (Ro52γCT) generated from a frameshift due to the lack of exon 6 in Ro52γ. Antibodies to Ro52Ex4 and Ro52γCT distinguish SLE patient subsets characterized by distinct clinical, laboratory, treatment, and transcriptional profiles that are not discerned by the "classical" anti-Ro52 antibodies. These studies uncover IFN-activated neutrophils as a key source of unique immunogenic forms of Ro52 in SLE. Moreover, the finding of Ro52Ex4 and Ro52γCT as core targets of anti-Ro52 antibodies focus interest on Ro52γ as the potential isoform toward which immunological tolerance is initially lost in SLE.


Asunto(s)
Lupus Eritematoso Sistémico , Autoanticuerpos , Autoantígenos/genética , Exones/genética , Humanos , Queratinocitos , Lupus Eritematoso Sistémico/genética
12.
Environ Sci Pollut Res Int ; 28(21): 26885-26894, 2021 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-33495956

RESUMEN

Agrochemicals can reach freshwater bodies by drift, leaching, or runoff, where they constitute complex mixtures. Given that glyphosate and cypermethrin are within the most worldwide used pesticides, they are likely to co-occur in freshwater bodies. The aim of this study was to analyze the interaction between glyphosate and cypermethrin formulations on the cladoceran Ceriodaphnia dubia (Richard 1894) through an acute toxicity test and on a zooplankton assemblage through a mesocosm (30 L) experiment. The 24-h LC50 of both isolated pesticides and their equitoxic mixture was obtained for C. dubia. The mesocosm was performed by exposing a zooplankton assemblage to both pesticides isolated and in combination. The acute toxicity of the equitoxic mixture in C. dubia was 3 and 4 times higher than the isolated toxicity of glyphosate and cypermethrin, respectively. The total toxic units of the mixture were 0.53, indicating a synergistic interaction. In the mesocosm experiment, both pesticides also interacted causing a synergistic negative effect in Cladocera and Copepoda abundances. No interactions between pesticides were found for Rotifera; therefore, the mixture effect was considered additive. It is suggested to continue analyzing pesticide mixture effects on the basis of complementary scales of analysis to reach more environmentally relevant information.


Asunto(s)
Cladóceros , Piretrinas , Contaminantes Químicos del Agua , Animales , Glicina/análogos & derivados , Piretrinas/toxicidad , Contaminantes Químicos del Agua/toxicidad , Zooplancton , Glifosato
13.
Water Environ Res ; 93(11): 2505-2526, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-34470080

RESUMEN

In this article, we performed a literature review on the metallic, metal oxide, and metalloid nanoparticles (NP) effects on freshwater microcrustaceans, specifically focusing on (i) the main factors influencing the NP toxicity and (ii) their main ecotoxicological effects. Also, given that most studies are currently developed on the standard test species Daphnia magna Straus, we analyzed (iii) the potential differences in the biological responses between D. magna and other freshwater microcrustacean, and (iv) the ecological implications of considering only D. magna as surrogate of other microcrustaceans. We found that NP effects on microcrustaceans depended on their intrinsic properties as well as the exposure conditions. Among the general responses to different NP, we identified body burial, feeding inhibition, biochemical effects, metabolic changes, and reproductive and behavioral alterations. The differences in the biological responses between D. magna and other freshwater microcrustacean rely on the morphology (size and shape), ecological traits (feeding mechanisms, life cycles), and intrinsic sensitivities. Thus, we strongly recommend the use of microcrustaceans species with different morphological, physiological, and ecological characteristics in future ecotoxicity tests with NP to provide relevant information with regulation purposes regarding the discharge of NP into aquatic environments. PRACTITIONER POINTS: Nanoparticles effects depend on intrinsic and external factors. Nanoparticles affect the morphology, physiology, and behavior. Effects on Daphnia differ from other microcrustaceans. The use of more diverse test species is suggested.


Asunto(s)
Nanopartículas del Metal , Metaloides , Nanopartículas , Contaminantes Químicos del Agua , Animales , Daphnia , Agua Dulce , Nanopartículas del Metal/toxicidad , Óxidos , Contaminantes Químicos del Agua/toxicidad
14.
Sci Total Environ ; 788: 147676, 2021 Sep 20.
Artículo en Inglés | MEDLINE | ID: mdl-34029815

RESUMEN

An increase in the spatial variability of rainfall is expected due to climate change. This implies increasing rainfall rates during spring and summer in the Pampas region, Argentina, period of maximum application of agrochemicals, which might cause an increase in pesticides and nutrients carried to surface water systems, as runoff by rainfall is one of the main pathways for diffuse pollution. The crops phenological stage can also affect pesticide and nutrient runoff since the applied agrochemicals and soil cover differ in each stage. In this study, we assessed the influence of rainfall and seasonal crop practices on water quality (nutrient and pesticide concentrations) in three streams in the Pampas region, Argentina. Five sampling campaigns were performed before and after three rainfall events during two different seasons of crop practices (SCP1, SCP2) and the physicochemical characteristics of the stream and runoff water were analyzed. The pesticide concentrations in the streams presented a general increase immediately after the rainfall event. Water quality was also affected, as an increase in ammonium, soluble reactive phosphorus (SRP), biological oxygen demand (BOD), and turbidity was observed. The crops phenological stage influenced pesticide and nutrient types and concentrations detected in the streams. During SCP1, mainly characterized by chemical fallow and sowing of soybean and vegetative growth and flowering of corn, ammonium, SRP, BOD, turbidity, and some pesticides, such as metolachlor, showed significantly higher results than those found in SCP2 (grain filling and vegetative growth of soybean and corn sowing). The pesticide concentrations detected in runoff water depended mostly on the pesticide solubility, the lateral slope of the streams, and the percentage of woody riparian vegetation cover. The results obtained show the relevance of assessing the influence of rainfall and crops phenological stages on the dynamics of surface water and on pesticide and nutrient runoff for environmental monitoring.

15.
Chemosphere ; 245: 125594, 2020 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-31855766

RESUMEN

This study aimed to assess how bioturbation by freshwater benthic macroinvertebrates with different biological traits alone or in combination could modify trace elements (TE) fate between sediment and water, and if water TE concentration and animal TE content impair their body stores. Three macroinvertebrate species were exposed to TE contaminated sediment for 7 days: the omnivorous Echinogammarus berilloni (Amphipoda), the sediment feeding Tubifex tubifex (Oligochaeta) and the filter feeding Pisidium sp. (Bivalvia). Treatments were one without invertebrates (control), two with amphipods or mussels alone, and the combinations amphipod-mussel, and amphipod-mussel-worms. Water TE concentration increased significantly in 2 or 3 species mesocosms, concerning mainly Rare Earth Elements, Cr, U and Pb, known to be associated to the colloidal phase. By contrast, water soluble TE were not affected by animals. For both, amphipods and mussels, TE body content increased with the number of coexisting species. For amphipods, this increase concerned both, soluble and colloid-associated TE, possibly due to intense contact and feeding from sediment and predation on tubificids. TE bioaccumulation in mussel was less important and characterized by soluble TE, with water filtration as most plausible uptake route. Protein, triglyceride and Whole Body Energy Budget increased in amphipods with the number of coexisting species (probably by feeding on mussels' feces and tubificids) whereas triglycerides declined in mussels (presumably filtration was disturbed by amphipods). This study highlights interspecific interactions as key drivers explaining both: TE bioturbation, depending on their water solubility or colloidal association, and the exposure/contamination of species through another species activity.


Asunto(s)
Sedimentos Geológicos/análisis , Invertebrados/metabolismo , Oligoelementos/análisis , Anfípodos/metabolismo , Animales , Bivalvos/metabolismo , Agua Dulce , Invertebrados/química , Oligoquetos/metabolismo , Oligoelementos/metabolismo , Contaminantes Químicos del Agua/análisis , Contaminantes Químicos del Agua/metabolismo
16.
Artículo en Portugués | LILACS-Express | LILACS | ID: biblio-1525611

RESUMEN

Introdução: A odontologia legal permite a identificação humana por meio da comparação de dados observados em uma documentação odontológica ante mortem (AM) com as informações coletadas post mortem (PM), sendo os exames radiográficos grandes aliados neste processo. Objetivo: Demostrar a contribuição da radiografia panorâmica como fonte de informação para a identificação humana. Relato do caso: foi encaminhado um corpo carbonizado, com parte da região bucomaxilofacial preservada e que ao exame necroscópico era possível identificar a presença de restaurações e ausências dentais. A apresentação de radiografia panorâmica anterior à morte e a realização de exame radiográfico panorâmico no corpo carbonizado possibilitou a comparação de pontos coincidentes e divergências explicáveis, permitindo a identificação positiva do caso. Conclusão: Ao final da perícia foi determinada a identidade da vítima e foi comprovada a importância da radiografia panorâmica para a identificação humana com base em caracteres identificadores anatômicos e terapêuticos presentes no complexo bucomaxilofacial


Introduction: Forensic dentistry allows human identification through the comparison of data observed in ante-mortem (AM) dental documentation with information collected post-mortem (PM), with radiographic examinations being great allies in this process. Objective: To demonstrate the contribution of panoramic radiography as a source of information for human identification. Case report: a charred body was sent, with part of the oral and maxillofacial region preserved and upon necroscopic examination it was possible to identify the presence of restorations and missing teeth. The presentation of a panoramic radiograph prior to death and the performance of a panoramic radiographic examination of the charred body made it possible to compare coincident points and explainable divergences, allowing positive identification of the case. Conclusion: At the end of the forensic examination of the case, the identity of the victim was determined and the importance of panoramic radiography for human identification based on anatomical and therapeutic identifying characters present in the oral and maxillofacial complex was proven

17.
Fisioter. Bras ; 20(5): 659-667, Outubro 24, 2019.
Artículo en Portugués | LILACS | ID: biblio-1281734

RESUMEN

Introdução: No âmbito acadêmico, os universitários, especialmente da área da saúde, estão expostos a diversas situações estressantes que podem afetar diretamente sua qualidade de vida. Objetivo: Caracterizar a qualidade de vida, ansiedade e estresse bem como a associação entre esses fatores em acadêmicos do curso de Fisioterapia da Universidade de Itaúna. Métodos: Foram convidados para o estudo todos os alunos matriculados no curso de fisioterapia da Universidade de Itaúna. Para avaliação foi utilizado um questionário sociodemográfico, o Medical Outcomes Study 36 (SF-36) e as escalas IDATE-traço, IDATE-estado e Escala de Percepção de Estresse ­ 10 (ESP-10). Resultados: Entre os 227 acadêmicos, a média de estresse foi de 23,53 (± 6,63), qualidade de vida no domínio físico 68,51 (± 18,29) e o mental, 55,17 ± 23,01. Os níveis de ansiedade variaram entre moderado e alto. Conclusão: Os graduandos de fisioterapia apresentam sintomas de estresse e ansiedade que podem influenciar diretamente na qualidade de vida. (AU)


Introduction: Academic students, especially in health care, are exposed to various stressful situations that can directly affect their quality of life. Objective: To characterize the quality of life, anxiety and stress as well as the association between these factors in the academic course of physical therapy at the University of Itaúna. Methods: All students enrolled in the course of physical therapy at the University of Itaúna were invited to the study. For evaluation we used a demographic questionnaire, the Medical Outcomes Study-Short Form 36 (SF-36) and the scales trait (STAI-T), state (STAI-S) and Perceived Stress Scale - PSS-10. Results: Among the 227 academics, the average stress was 23.53 ± 6.63 points, quality of life in the physical domain 68.51 ± 18.29 points and mental, 55.17 ± 23.01. Anxiety levels ranged between moderate and high. Conclusion: The physical therapy students present symptoms of stress and anxiety and these can influence directly on the quality of life. (AU)


Asunto(s)
Humanos , Ansiedad , Calidad de Vida , Estudiantes , Agotamiento Psicológico , Salud del Estudiante , Especialidad de Fisioterapia
18.
México, D.F; Trillas; 28 nov. 1996. 160 p. ilus, mapas.
Monografía en Español | LILACS | ID: lil-217493

RESUMEN

Texto de apoyo didáctico, dirigido a los alumnos y profesores de educación secundaria, quienes se encuentran en el proceso enseñanza-aprendizaje en la materia de Educación Ambiental, dadas las condiciones en las que se encuentra el medio ambiente en México, así como las medidas que deben tomarse con respecto al ambiente físico y social de cada alumno. El documento se divide en seis unidades: 1. LOS ECOSISTEMAS 2. LA BASURA 3. CONTAMINACION DEL SUELO Y DEL AGUA A. Contaminación del suelo B. Contaminación del agua 4. CONTAMINACION DE LA ATMOSFERA A. Características de la atmósfera B. Principales fuentes contaminantes del aire C. Condiciones ambientales de la ciudad de México 5. ALTERACION DEL EQUILIBRIO ECOLOGICO POR LA DESFORESTACION A. La desforestación y la ruptura del equilibrio ecológico B. Desforestación con fines agrícolas y ganaderos C. Desforestación con fines ganaderos D. Crecimiento urbano del Valle de México E. Algunas áreas verdes de conservación ecológica 6. CONTAMINACION SOCIAL A. El consumismo y el ambiente B. Medios de comunicación y publicidad C. Estrategias para evitar el consumismo y preservar el medio


Asunto(s)
Contaminación Ambiental , Ecología , Ambiente , Educación en Salud
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