Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

Phosphoinositide acyl chain saturation drives CD8⁺ effector T cell signaling and function.

Edwards-Hicks, Joy; Apostolova, Petya; Buescher, Joerg M; Maib, Hannes; Stanczak, Michal A; Corrado, Mauro; Klein Geltink, Ramon I; Maccari, Maria Elena; Villa, Matteo; Carrizo, Gustavo E; Sanin, David E; Baixauli, Francesc; Kelly, Beth; Curtis, Jonathan D; Haessler, Fabian; Patterson, Annette; Field, Cameron S; Caputa, George; Kyle, Ryan L; Soballa, Melanie; Cha, Minsun; Paul, Harry; Martin, Jacob; Grzes, Katarzyna M; Flachsmann, Lea; Mitterer, Michael; Zhao, Liang; Winkler, Frances; Rafei-Shamsabadi, David Ali; Meiss, Frank; Bengsch, Bertram; Zeiser, Robert; Puleston, Daniel J; O'Sullivan, David; Pearce, Edward J; Pearce, Erika L.

Nat Immunol ; 24(3): 516-530, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36732424

2.

Lactic acid and lactate: revisiting the physiological roles in the tumor microenvironment.

Apostolova, Petya; Pearce, Erika L.

Trends Immunol ; 43(12): 969-977, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36319537

3.

Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation.

Ho, Jenny N H G; Schmidt, Dominik; Lowinus, Theresa; Ryoo, Jeongmin; Dopfer, Elaine-Pashupati; Gonzalo Núñez, Nicolás; Costa-Pereira, Sara; Toffalori, Cristina; Punta, Marco; Fetsch, Viktor; Wertheimer, Tobias; Rittmann, Marie-Claire; Braun, Lukas M; Follo, Marie; Briere, Christelle; Vinnakota, Janaki Manoja; Langenbach, Marlene; Koppers, Felicitas; Shoumariyeh, Khalid; Engel, Helena; Rückert, Tamina; Märklin, Melanie; Holzmayer, Samuel; Illert, Anna L; Magon, Federica; Andrieux, Geoffroy; Duquesne, Sandra; Pfeifer, Dietmar; Staniek, Julian; Rizzi, Marta; Miething, Cornelius; Köhler, Natalie; Duyster, Justus; Menssen, Hans D; Boerries, Melanie; Buescher, Joerg M; Cabezas-Wallscheid, Nina; Blazar, Bruce R; Apostolova, Petya; Vago, Luca; Pearce, Erika L; Becher, Burkhard; Zeiser, Robert.

Blood ; 140(10): 1167-1181, 2022 09 08.

Artículo en Inglés | MEDLINE | ID: mdl-35853161

4.

Fever supports CD8⁺ effector T cell responses by promoting mitochondrial translation.

O'Sullivan, David; Stanczak, Michal A; Villa, Matteo; Uhl, Franziska M; Corrado, Mauro; Klein Geltink, Ramon I; Sanin, David E; Apostolova, Petya; Rana, Nisha; Edwards-Hicks, Joy; Grzes, Katarzyna M; Kabat, Agnieszka M; Kyle, Ryan L; Fabri, Mario; Curtis, Jonathan D; Buck, Michael D; Patterson, Annette E; Regina, Annamaria; Field, Cameron S; Baixauli, Francesc; Puleston, Daniel J; Pearce, Edward J; Zeiser, Robert; Pearce, Erika L.

Proc Natl Acad Sci U S A ; 118(25)2021 06 22.

Artículo en Inglés | MEDLINE | ID: mdl-34161266

5.

Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation-Immune signature correlates with response.

Apostolova, Petya; Kreutmair, Stefanie; Toffalori, Cristina; Punta, Marco; Unger, Susanne; Burk, Ann-Cathrin; Wehr, Claudia; Maas-Bauer, Kristina; Melchinger, Wolfgang; Haring, Eileen; Hoefflin, Rouven; Shoumariyeh, Khalid; Hupfer, Valerie; Lauer, Eliza Maria; Duquesne, Sandra; Lowinus, Theresa; Gonzalo Núñez, Nicolás; Alberti, Chiara; da Costa Pereira, Sara; Merten, Carla Helena; Power, Laura; Weiss, Matthias; Böke, Caroline; Pfeifer, Dietmar; Marks, Reinhard; Bertz, Hartmut; Wäsch, Ralph; Ihorst, Gabriele; Gentner, Bernhard; Duyster, Justus; Boerries, Melanie; Andrieux, Geoffroy; Finke, Juergen; Becher, Burkhard; Vago, Luca; Zeiser, Robert.

Br J Haematol ; 203(2): 264-281, 2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-37539479

6.

Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans.

Norona, Johana; Apostolova, Petya; Schmidt, Dominik; Ihlemann, Rebekka; Reischmann, Nadine; Taylor, Gregory; Köhler, Natalie; de Heer, Jocelyn; Heeg, Steffen; Andrieux, Geoffroy; Siranosian, Benjamin A; Schmitt-Graeff, Annette; Pfeifer, Dietmar; Catalano, Antonella; Frew, Ian J; Proietti, Michele; Grimbacher, Bodo; Bulashevska, Alla; Bhatt, Ami S; Brummer, Tilman; Clauditz, Till; Zabelina, Tatjana; Kroeger, Nicolaus; Blazar, Bruce R; Boerries, Melanie; Ayuk, Francis; Zeiser, Robert.

Blood ; 136(12): 1442-1455, 2020 09 17.

Artículo en Inglés | MEDLINE | ID: mdl-32542357

7.

Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease.

Haring, Eileen; Andrieux, Geoffroy; Uhl, Franziska M; Krausz, Máté; Proietti, Michele; Sauer, Barbara; Esser, Philipp R; Martin, Stefan F; Pfeifer, Dietmar; Schmitt-Graeff, Annette; Duyster, Justus; Köhler, Natalie; Grimbacher, Bodo; Boerries, Melanie; Aumann, Konrad; Zeiser, Robert; Apostolova, Petya.

Haematologica ; 107(7): 1538-1554, 2022 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-34407601

8.

IRE1 and PERK signaling regulates inflammatory responses in a murine model of contact hypersensitivity.

Gendrisch, Fabian; Völkel, Lukas; Fluck, Melanie; Apostolova, Petya; Zeiser, Robert; Jakob, Thilo; Martin, Stefan F; Esser, Philipp R.

Allergy ; 77(3): 966-978, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-34314538

9.

Immunization against poly-N-acetylglucosamine reduces neutrophil activation and GVHD while sparing microbial diversity.

Hülsdünker, Jan; Thomas, Oliver S; Haring, Eileen; Unger, Susanne; Gonzalo Núñez, Nicolás; Tugues, Sonia; Gao, Zhan; Duquesne, Sandra; Cywes-Bentley, Colette; Oyardi, Ozlem; Kirschnek, Susanne; Schmitt-Graeff, Annette; Pabst, Oliver; Koenecke, Christian; Duyster, Justus; Apostolova, Petya; Blaser, Martin J; Becher, Burkhard; Pier, Gerald B; Häcker, Georg; Zeiser, Robert.

Proc Natl Acad Sci U S A ; 116(41): 20700-20706, 2019 10 08.

Artículo en Inglés | MEDLINE | ID: mdl-31527267

10.

Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect.

Haring, Eileen; Uhl, Franziska M; Andrieux, Geoffroy; Proietti, Michele; Bulashevska, Alla; Sauer, Barbara; Braun, Lukas M; de Vega Gomez, Enrique; Esser, Philipp R; Martin, Stefan F; Pfeifer, Dietmar; Follo, Marie; Schmitt-Graeff, Annette; Buescher, Joerg; Duyster, Justus; Grimbacher, Bodo; Boerries, Melanie; Pearce, Erika L; Zeiser, Robert; Apostolova, Petya.

Haematologica ; 106(8): 2131-2146, 2021 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-32675222

11.

Allo-HCT: damaged T cells don't bite.

Apostolova, Petya.

Blood ; 141(13): 1507-1508, 2023 03 30.

Artículo en Inglés | MEDLINE | ID: mdl-36995707

12.

Extracorporeal Photopheresis for Colitis Induced by Checkpoint-Inhibitor Therapy.

Apostolova, Petya; Unger, Susanne; von Bubnoff, Dagmar; Meiss, Frank; Becher, Burkhard; Zeiser, Robert.

N Engl J Med ; 382(3): 294-296, 2020 01 16.

Artículo en Inglés | MEDLINE | ID: mdl-31940706

13.

Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells.

Schönle, Anne; Hartl, Frederike A; Mentzel, Jan; Nöltner, Theresa; Rauch, Katharina S; Prestipino, Alessandro; Wohlfeil, Sebastian A; Apostolova, Petya; Hechinger, Anne-Kathrin; Melchinger, Wolfgang; Fehrenbach, Kerstin; Guadamillas, Marta C; Follo, Marie; Prinz, Gabriele; Ruess, Ann-Katrin; Pfeifer, Dietmar; del Pozo, Miguel Angel; Schmitt-Graeff, Annette; Duyster, Justus; Hippen, Keli I; Blazar, Bruce R; Schachtrup, Kristina; Minguet, Susana; Zeiser, Robert.

Blood ; 127(15): 1930-9, 2016 Apr 14.

Artículo en Inglés | MEDLINE | ID: mdl-26837700

14.

Matching for the nonconventional MHC-I MICA gene significantly reduces the incidence of acute and chronic GVHD.

Carapito, Raphael; Jung, Nicolas; Kwemou, Marius; Untrau, Meiggie; Michel, Sandra; Pichot, Angélique; Giacometti, Gaëlle; Macquin, Cécile; Ilias, Wassila; Morlon, Aurore; Kotova, Irina; Apostolova, Petya; Schmitt-Graeff, Annette; Cesbron, Anne; Gagne, Katia; Oudshoorn, Machteld; van der Holt, Bronno; Labalette, Myriam; Spierings, Eric; Picard, Christophe; Loiseau, Pascale; Tamouza, Ryad; Toubert, Antoine; Parissiadis, Anne; Dubois, Valérie; Lafarge, Xavier; Maumy-Bertrand, Myriam; Bertrand, Frédéric; Vago, Luca; Ciceri, Fabio; Paillard, Catherine; Querol, Sergi; Sierra, Jorge; Fleischhauer, Katharina; Nagler, Arnon; Labopin, Myriam; Inoko, Hidetoshi; von dem Borne, Peter A; Kuball, Jürgen; Ota, Masao; Katsuyama, Yoshihiko; Michallet, Mauricette; Lioure, Bruno; Peffault de Latour, Régis; Blaise, Didier; Cornelissen, Jan J; Yakoub-Agha, Ibrahim; Claas, Frans; Moreau, Philippe; Milpied, Noël.

Blood ; 128(15): 1979-1986, 2016 10 13.

Artículo en Inglés | MEDLINE | ID: mdl-27549307

15.

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.

Koehn, Brent H; Apostolova, Petya; Haverkamp, Jessica M; Miller, Jeffrey S; McCullar, Valarie; Tolar, Jakub; Munn, David H; Murphy, William J; Brickey, Willie June; Serody, Jonathan S; Gabrilovich, Dmitry I; Bronte, Vincenzo; Murray, Peter J; Ting, Jenny P-Y; Zeiser, Robert; Blazar, Bruce R.

Blood ; 126(13): 1621-8, 2015 Sep 24.

Artículo en Inglés | MEDLINE | ID: mdl-26265697

16.

A Novel Function for P2Y2 in Myeloid Recipient-Derived Cells during Graft-versus-Host Disease.

Klämbt, Verena; Wohlfeil, Sebastian A; Schwab, Lukas; Hülsdünker, Jan; Ayata, Korcan; Apostolova, Petya; Schmitt-Graeff, Annette; Dierbach, Heide; Prinz, Gabriele; Follo, Marie; Prinz, Marco; Idzko, Marco; Zeiser, Robert.

J Immunol ; 195(12): 5795-804, 2015 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-26538394

17.

Metabolic instruction of the graft-versus-leukemia immunity.

Burk, Ann-Cathrin; Apostolova, Petya.

Front Immunol ; 15: 1347492, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38500877

18.

Prostaglandin E₂ controls the metabolic adaptation of T cells to the intestinal microenvironment.

Villa, Matteo; Sanin, David E; Apostolova, Petya; Corrado, Mauro; Kabat, Agnieszka M; Cristinzio, Carmine; Regina, Annamaria; Carrizo, Gustavo E; Rana, Nisha; Stanczak, Michal A; Baixauli, Francesc; Grzes, Katarzyna M; Cupovic, Jovana; Solagna, Francesca; Hackl, Alexandra; Globig, Anna-Maria; Hässler, Fabian; Puleston, Daniel J; Kelly, Beth; Cabezas-Wallscheid, Nina; Hasselblatt, Peter; Bengsch, Bertram; Zeiser, Robert; Buescher, Joerg M; Pearce, Edward J; Pearce, Erika L.

Nat Commun ; 15(1): 451, 2024 Jan 11.

Artículo en Inglés | MEDLINE | ID: mdl-38200005

19.

Prostaglandin E ₂ controls the metabolic adaptation of T cells to the intestinal microenvironment.

Villa, Matteo; Sanin, David E; Apostolova, Petya; Corrado, Mauro; Kabat, Agnieszka M; Cristinzio, Carmine; Regina, Annamaria; Carrizo, Gustavo E; Rana, Nisha; Stanczak, Michal A; Baixauli, Francesc; Grzes, Katarzyna M; Cupovic, Jovana; Solagna, Francesca; Hackl, Alexandra; Globig, Anna-Maria; Hässler, Fabian; Puleston, Daniel J; Kelly, Beth; Cabezas-Wallscheid, Nina; Hasselblatt, Peter; Bengsch, Bertram; Zeiser, Robert; Buescher, Joerg M; Pearce, Edward J; Pearce, Erika L.

bioRxiv ; 2023 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-36993703

20.

Retraction notice to "Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer" [Canc. Lett. 520 (2021) 385-399].

Taromi, Sanaz; Firat, Elke; Simonis, Alexander; Braun, Lukas M; Apostolova, Petya; Elze, Mirjam; Passlick, Bernward; Schumacher, Alicia; Lagies, Simon; Frey, Anna; Schmitt-Graeff, Annette; Burger, Meike; Schmittlutz, Katrin; Follo, Marie; von Elverfeldt, Dominik; Zhu, Xuekai; Kammerer, Bernd; Diederichs, Sven; Duyster, Justus; Manz, Markus G; Niedermann, Gabriele; Zeiser, Robert.

Cancer Lett ; 537: 215680, 2022 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-35461758

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