RESUMEN
BACKGROUND: Allergic contact dermatitis from (meth)acrylic monomers (ACDMA) in manicure products is increasing. OBJECTIVE: To evaluate the prognosis, work performance impairment and sequelae of a cohort of beauticians and manicure consumers with ACDMA sensitized from the exposure to manicure products. METHODS: We conducted a telephone survey with patients diagnosed with ACDMA. RESULTS: One hundred and six patients were evaluated, including 75 (70.8%) beauticians and 31 (29.2%) consumers. All were women with a mean age of 39 (19-62). Thirty-seven of 75 beauticians (49.3%) continued to work. Twenty-seven of 106 (25.5%) patients continued to use manicure products with (meth)acrylates regularly. Seventeen of 51 (33.3%) patients who discontinued the exposure described ongoing nail/periungual changes. Nine of 58 (15.5%) patients who required dental restoration, orthodontic or occlusal splint materials recalled reactions from them; and, 25 of 96 (26%) who used sanitary napkins recalled intolerance to them starting after the diagnosis of ACDMA. Fifteen of 25 (60%) discontinued the use of sanitary napkins. CONCLUSION: 49.3% beauticians continued to work; most patients stopped wearing acrylic manicure materials; reactions from dental materials were not uncommon, however, removal of dental materials was never required; and, reactions to sanitary napkins developing after the diagnosis of ACDMA were common most leading to discontinuation of use.
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Dermatitis Alérgica por Contacto , Dermatitis Profesional , Humanos , Femenino , Adulto , Masculino , Dermatitis Alérgica por Contacto/diagnóstico , Acrilatos/efectos adversos , Pruebas del Parche , Pronóstico , Materiales Dentales , Metacrilatos/efectos adversosRESUMEN
Introduction: Untreated, severe, symptomatic aortic stenosis is associated with an ominous diagnosis without intervention. This study aims to determine the impact of the COVID-19 pandemic on the mortality of patients with severe stenosis during the first wave and compare it with the same period last year. Methods: All patients who went to the hospitals in an Spanish region during the first wave, and in the same period of previous year, were analyzed using artificial intelligence-based software, evaluating the mortality of patients with severe aortic stenosis with and without COVID-19 during the pandemic and the pre-COVID era. Mortality of the 3 groups was compared. Regarding cardiac surgeries was a tendency to decrease (P = .07) in patients without COVID-19 between the pandemic and the previous period was observed. A significant decrease of surgeries between patients with COVID-19 and without COVID-19 was shown. Results: Data showed 13.82% less admitted patients during the first wave. A total of 1,112 of them had aortic stenosis and 5.48% were COVID-19 positive. Mortality was higher (P = .01), in COVID-19 negative during the pandemic (4.37%) versus those in the pre-COVID-19 era (2.57%); it was also in the COVID-19 positive group (11.47%), versus COVID-19 negative (4.37%) during the first wave (P = .01). Conclusions: The study revealed a decrease in patients who went to the hospital and an excess of mortality in patients with severe aortic stenosis without infection during the first wave, compared to the same period last year; and also, in COVID-19 positive patients versus COVID-19 negative.
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Industria de la Construcción , Dermatitis Alérgica por Contacto , Dermatitis Profesional , Humanos , Acrilatos/efectos adversos , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/diagnóstico , Dermatitis Profesional/etiología , Alérgenos , Metacrilatos , Pruebas del ParcheRESUMEN
INTRODUCTION: Untreated, severe, symptomatic aortic stenosis is associated with an ominous diagnosis without intervention. This study aims to determine the impact of the COVID-19 pandemic on the mortality of patients with severe stenosis during the first wave and compare it with the same period last year. METHODS: All patients who went to the hospitals in a spanish region during the first wave, and in the same period of previous year, were analysed using Artificial Intelligence-based software, evaluating the mortality of patients with severe aortic stenosis with and without COVID-19 during the pandemic and the pre-COVID era. Mortality of the three groups were compared. Regarding cardiac surgeries was a tendency to decrease (p = .07) in patients without COVID-19 between the pandemic and the previous period was observed. A significant decrease of surgeries between patients with COVID-19 and without COVID-19 was shown. RESULTS: Data showed 13.82% less admitted patients during the first wave. 1112 of them, had aortic stenosis and 5.48% were COVID-19 positive. Mortality was higher (p = .01), in COVID-19 negative during the pandemic (4.37%) versus those in the pre-COVID19 era (2.57%); it was also in the COVID-19 positive group (11.47%), versus covid-19 negative (4.37%) during the first wave (p = .01). CONCLUSIONS: The study revealed a decrease in patients who went to the hospital and an excess of mortality in patients with severe AD without infection during the first wave, compared to the same period last year; and also, in COVID-19 positive patients versus COVID-19 negative.
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Estenosis de la Válvula Aórtica , COVID-19 , Humanos , Pandemias , Inteligencia Artificial , Factores de Riesgo , Estenosis de la Válvula Aórtica/complicaciones , Estenosis de la Válvula Aórtica/cirugía , Estenosis de la Válvula Aórtica/diagnósticoRESUMEN
This is a descriptive study designed to assess the predictive value of intraocular pressure (IOP) measurement in GPs' offices in an urban healthcare site using Tono-pen XL. A total of 2044 patients, aged > or =40 years, were enrolled by consecutive sampling from patients visiting the GP. Those participants who had IOP > or =21 mmHg were referred to the ophthalmologist. Of the 226 then tested, ocular hypertension was confirmed in 100 participants (4.89%, 95% CI [confidence interval] = 3.93 to 5.85%). Predictive value was 44.2%. These results suggest the validity of using Tono-pen XL in the GP's office to detect ocular hypertension.
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Medicina Familiar y Comunitaria , Glaucoma/prevención & control , Presión Intraocular/fisiología , Hipertensión Ocular/diagnóstico , Tonometría Ocular/instrumentación , Adulto , Anciano , Estudios Transversales , Femenino , Glaucoma/complicaciones , Humanos , Masculino , Persona de Mediana Edad , Hipertensión Ocular/complicaciones , Valor Predictivo de las Pruebas , EspañaRESUMEN
Lens autofluorescence originates from an accumulation of fluorescent substances such as the tryptophan-derived residues and protein aggregations, which are associated with the preclinical progress of cataractogenesis, diabetes and lens aging. Our purpose is to determine if pregnancy alters the typical constituents of the lens autofluorescence. Fifteen healthy pregnant women (22 eyes) who were in their third trimester of pregnancy and 23 age-matched healthy controls (37 eyes, non-pregnant females). Lens autofluorescence, lens transmission and corneal autofluorescence were studied with fluorophotometry. The lens autofluorescence values were 358+/-151 ng ml(-1) in the control group and 201+/-110 ng ml(-1) in the pregnants women. The difference was significant (p=0.0074). Lens transmission values were 0.93+/-0.02 ng ml(-1) in the control group and 0.94+/-0.02 ng ml(-1) in the pregnants women: the difference was not significant. Corneal autofluorescence values were 21.9+/-7.5 ng ml(-1) in the control group and 18.2+/-5.8 ng ml(-1) in the pregnant women. The difference was not significant. Our study showed a significant decrease in lens autofluorescence in pregnant women compared to a normal population. The decrease can be partly attributed to the aqueous component of the lens that increases significantly during the final trimester of pregnancy and that this provokes a dilution of the fluorescent substances.
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Cristalino/fisiología , Embarazo/fisiología , Adulto , Córnea/fisiología , Femenino , Fluorescencia , Fluorofotometría/métodos , Humanos , Tercer Trimestre del EmbarazoRESUMEN
OBJECTIVE: Local corticosteroid injections, commonly accepted by rheumatologists to be effective treating painful shoulder, have shown controversial results. High frequency ultrasonography is an accurate and safe imaging modality for guiding musculoskeletal injections. We prospectively compared the short term response to randomized blind injection versus sonographic-guided injection of local corticosteroid in patients with painful shoulder. METHODS: We studied 41 consecutive patients with painful shoulder. Patients with previous trauma or chronic inflammatory arthritis were excluded. No patient had received previous physiotherapy or local steroid injection in the shoulder. Patients were randomized to receive either a blind subacromial injection of 20 mg triamcinolone (Group 1, n = 20) or a sonographic guided injection of 20 mg triamcinolone (Group 2, n = 21) by the same rheumatologist blinded to the clinical evaluation. In both groups we recorded shoulder abnormalities and the location of the steroid postinjection by ultrasound. Each patient was clinically assessed within 5 days before injection and 6 weeks after injection by another rheumatologist without knowledge of the injection technique performed. Clinical assessment included demographic and clinical data, a visual analog scale (VAS) for pain (0-100), the Shoulder Function Assessment (SFA) scale (0-70), and postinjection adverse effects. No patient received physical therapy during the followup period. Initially, demographic, clinical, and ultrasonographic findings in both groups showed no significant differences. RESULTS: Six weeks after injection, the VAS and the SFA score showed a significantly greater improvement in Group 2 compared with Group 1 (mean VAS score change 34.9 for Group 2 vs 7.1 for Group 1, p < 0.001; and mean SFA score change 15 for Group 2 vs 5.6 for Group 1, p = 0.012). One patient in Group 1 reported mild postinjection adverse effects. CONCLUSION: We suggest that sonographic-guided corticosteroid injections should be indicated, at least, in patients with poor response to previous blind injection to ensure accurate medication placement in order to improve therapeutic effectiveness.