Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

The information theory of aging has not been tested.

Timmons, James A; Brenner, Charles.

Cell ; 187(5): 1101-1102, 2024 Feb 29.

Artículo en Inglés | MEDLINE | ID: mdl-38428390

2.

Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging.

Sato, Shogo; Solanas, Guiomar; Peixoto, Francisca Oliveira; Bee, Leonardo; Symeonidi, Aikaterini; Schmidt, Mark S; Brenner, Charles; Masri, Selma; Benitah, Salvador Aznar; Sassone-Corsi, Paolo.

Cell ; 170(4): 664-677.e11, 2017 Aug 10.

Artículo en Inglés | MEDLINE | ID: mdl-28802039

3.

Control of NAD⁺ homeostasis by autophagic flux modulates mitochondrial and cardiac function.

Zhang, Quanjiang; Li, Zhonggang; Li, Qiuxia; Trammell, Samuel Aj; Schmidt, Mark S; Pires, Karla Maria; Cai, Jinjin; Zhang, Yuan; Kenny, Helena; Boudina, Sihem; Brenner, Charles; Abel, E Dale.

EMBO J ; 43(3): 362-390, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38212381

4.

NAD⁺ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging.

Levine, Daniel C; Hong, Heekyung; Weidemann, Benjamin J; Ramsey, Kathryn M; Affinati, Alison H; Schmidt, Mark S; Cedernaes, Jonathan; Omura, Chiaki; Braun, Rosemary; Lee, Choogon; Brenner, Charles; Peek, Clara Bien; Bass, Joseph.

Mol Cell ; 78(5): 835-849.e7, 2020 06 04.

Artículo en Inglés | MEDLINE | ID: mdl-32369735

5.

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity.

Heer, Collin D; Sanderson, Daniel J; Voth, Lynden S; Alhammad, Yousef M O; Schmidt, Mark S; Trammell, Samuel A J; Perlman, Stanley; Cohen, Michael S; Fehr, Anthony R; Brenner, Charles.

J Biol Chem ; 295(52): 17986-17996, 2020 12 25.

Artículo en Inglés | MEDLINE | ID: mdl-33051211

6.

Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD.

Roboon, Jureepon; Hattori, Tsuyoshi; Ishii, Hiroshi; Takarada-Iemata, Mika; Nguyen, Dinh Thi; Heer, Collin D; O'Meally, Denis; Brenner, Charles; Yamamoto, Yasuhiko; Okamoto, Hiroshi; Higashida, Haruhiro; Hori, Osamu.

J Neurochem ; 158(2): 311-327, 2021 07.

Artículo en Inglés | MEDLINE | ID: mdl-33871064

7.

Interleukin-8 drives CD38 to form NAADP from NADP⁺ and NAAD in the endolysosomes to mobilize Ca²⁺ and effect cell migration.

Nam, Tae-Sik; Park, Dae-Ryoung; Rah, So-Young; Woo, Tae-Gyu; Chung, Hun Taeg; Brenner, Charles; Kim, Uh-Hyun.

FASEB J ; 34(9): 12565-12576, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32717131

8.

Evaluating Mixture Solution™- rapid and non-MCMC probabilistic mixture analysis.

Lucassen, Anton; Ehlers, Karen; Grobler, Paul J; Brenner, Charles H.

Int J Legal Med ; 135(6): 2275-2284, 2021 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-34599363

9.

Pharmacological bypass of NAD⁺ salvage pathway protects neurons from chemotherapy-induced degeneration.

Liu, Hui-Wen; Smith, Chadwick B; Schmidt, Mark S; Cambronne, Xiaolu A; Cohen, Michael S; Migaud, Marie E; Brenner, Charles; Goodman, Richard H.

Proc Natl Acad Sci U S A ; 115(42): 10654-10659, 2018 10 16.

Artículo en Inglés | MEDLINE | ID: mdl-30257945

10.

Modulation of the cardiac sodium channel Na_V1.5 peak and late currents by NAD⁺ precursors.

Matasic, Daniel S; Yoon, Jin-Young; McLendon, Jared M; Mehdi, Haider; Schmidt, Mark S; Greiner, Alexander M; Quinones, Pravda; Morgan, Gina M; Boudreau, Ryan L; Irani, Kaikobad; Brenner, Charles; London, Barry.

J Mol Cell Cardiol ; 141: 70-81, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32209328

11.

Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy.

Diguet, Nicolas; Trammell, Samuel A J; Tannous, Cynthia; Deloux, Robin; Piquereau, Jérôme; Mougenot, Nathalie; Gouge, Anne; Gressette, Mélanie; Manoury, Boris; Blanc, Jocelyne; Breton, Marie; Decaux, Jean-François; Lavery, Gareth G; Baczkó, István; Zoll, Joffrey; Garnier, Anne; Li, Zhenlin; Brenner, Charles; Mericskay, Mathias.

Circulation ; 137(21): 2256-2273, 2018 05 22.

Artículo en Inglés | MEDLINE | ID: mdl-29217642

12.

Emerging potential benefits of modulating NAD⁺ metabolism in cardiovascular disease.

Matasic, Daniel S; Brenner, Charles; London, Barry.

Am J Physiol Heart Circ Physiol ; 314(4): H839-H852, 2018 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-29351465

13.

Nicotinamide riboside, a form of vitamin B₃, protects against excitotoxicity-induced axonal degeneration.

Vaur, Pauline; Brugg, Bernard; Mericskay, Mathias; Li, Zhenlin; Schmidt, Mark S; Vivien, Denis; Orset, Cyrille; Jacotot, Etienne; Brenner, Charles; Duplus, Eric.

FASEB J ; 31(12): 5440-5452, 2017 12.

Artículo en Inglés | MEDLINE | ID: mdl-28842432

14.

Calorie restriction-mediated replicative lifespan extension in yeast is non-cell autonomous.

Mei, Szu-Chieh; Brenner, Charles.

PLoS Biol ; 13(1): e1002048, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25633578

15.

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk.

Trammell, Samuel Aj; Yu, Liping; Redpath, Philip; Migaud, Marie E; Brenner, Charles.

J Nutr ; 146(5): 957-63, 2016 05.

Artículo en Inglés | MEDLINE | ID: mdl-27052539

16.

Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications.

Ghanta, Sirisha; Grossmann, Ruth E; Brenner, Charles.

Crit Rev Biochem Mol Biol ; 48(6): 561-74, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24050258

17.

Metabolism: Targeting a fat-accumulation gene.

Brenner, Charles.

Nature ; 508(7495): 194-5, 2014 Apr 10.

Artículo en Inglés | MEDLINE | ID: mdl-24717510

18.

Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.

Fagan, Rebecca L; Cryderman, Diane E; Kopelovich, Levy; Wallrath, Lori L; Brenner, Charles.

J Biol Chem ; 288(33): 23858-67, 2013 Aug 16.

Artículo en Inglés | MEDLINE | ID: mdl-23839987

19.

NAD in pathological cardiac remodeling: Metabolic regulation and beyond.

Norambuena-Soto, Ignacio; Deng, Yingfeng; Brenner, Charles; Lavandero, Sergio; Wang, Zhao V.

Biochim Biophys Acta Mol Basis Dis ; 1870(3): 167038, 2024 03.

Artículo en Inglés | MEDLINE | ID: mdl-38281710

20.

A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment.

Orr, Miranda E; Kotkowski, Eithan; Ramirez, Paulino; Bair-Kelps, Darcy; Liu, Qianqian; Brenner, Charles; Schmidt, Mark S; Fox, Peter T; Larbi, Anis; Tan, Crystal; Wong, Glenn; Gelfond, Jonathan; Frost, Bess; Espinoza, Sara; Musi, Nicolas; Powers, Becky.

Geroscience ; 46(1): 665-682, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-37994989

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