1.
Org Biomol Chem
; 15(37): 7802-7812, 2017 Sep 26.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28876013
RESUMEN
Lipo-chitotetrasaccharide analogues where one central GlcNAc residue was replaced by a triazole unit have been synthesized from a derivative obtained by chitin depolymerization and a functionalized N-acetyl-glucosamine via the copper-catalyzed azide-alkyne cycloaddition. Their evaluation in a binding assay using LYR3, a putative lipo-chitooligosaccharide receptor in Medicago truncatula, shows a complete loss of binding.