Adverse events following booster doses of diphtheria-tetanus-inactivated poliovirus and acellular pertussis vaccines for 4-year-old children in The Netherlands.

The aim of the study was to assess the incidence and severity of local reactions and systemic events among 4-year-old children receiving a fifth dose of diphtheria-tetanus-inactivated poliovirus (dT-IPV) and acellular pertussis (aP) vaccines. Of 810 children, 483 had no adverse events following immunization. Of the reported local reactions of 281 children, pain was the most frequent (n=246). Eighty-one children developed redness, and 54, swelling. Pain, reduced use of the arm, redness, and swelling occurred significantly more often at the dT-IPV injection site than at the aP injection site (p<0.05). Local reactions were mainly mild and transient. Among the 104 reported systemic events, fever was the most frequent (n=42). In general, the vaccinations for the 4-year-olds are well tolerated.

Measuring maximum holding times and perception of static elevated work and forward bending in healthy young adults.

The objectives of this study were to investigate the maximum holding times (MHT) of two highly stressful postures: standing in a forward bend position and performing elevated work in a standing position. The relationship between perceived exertion and MHT was also studied. Subjects were 44 young adults, age 20-29 years (25 female, 19 male). A test-retest design was used to establish reliability. Mean maximum holding times for forward bending and elevated work were respectively 14.51 and 16.18 min with large interindividual variations. A logarithmic rather than a linear relation between perceived exertion and performance is found. It is not possible to reliably predict MHTs from subjective data. Test-retest correlation is high (n = 19, r = 0.716 and 0.813, p < 0.001), and the scores did not differ significantly (p < 0.005), indicating a reliable procedure. The average holding times of the population studied are higher than expected from literature. Neither generic formulas, curve estimations, or predictions can reliably predict an individual's MHT. An individual's MHTs are best tested through performance based testing.