Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 25
Filtrar
1.
Niger J Clin Pract ; 25(5): 569-575, 2022 May.
Artículo en Inglés | MEDLINE | ID: mdl-35593597

RESUMEN

Background: Studying ocular biometric parameters in different populations and determining the relationship with personal characteristics can provide valuable information about ocular growth and help provide a better understanding of refractive errors. Aims: To describe distributions of ocular biometry and to evaluate its associations with age, gender, spheric equivalent in Turkish children. Patients and Methods: In this prospective study 344 children aged 3-14 years were evaluated. Parameters studied included axial length (AL), anterior chamber depth (ACD), and mean corneal radius (CR) measured with optical biometry. Cycloplegic refraction values were obtained using autorefractometer. The change of biometric parameters according to age and gender were evaluated. The relationship between ocular biometry parameters with refraction and age was analyzed by linear regression. Results: Mean spherical equivalent (SE), AL, ACD and AL/CR observed to be lowest in the preschooler group (P < 0.001). SE reduced with age, and a weak correlation observed between SE and age (r = -0.333). AL and ACD had moderate and weak positive correlations with age respectively (r = 0.511; r = 0.304). There were negative correlations between SE with AL, ACD and AL/CR (r = -0.826; r = -0.540; r = -0.886). The strongest correlation with SE among these parameters was identified for AL/CR. AL and ACD were higher in boys, while the CR was lower in girls (p < 0.001). Conclusion: While AL in children in late schooler group is higher than European countries, it shows similar characteristics in early schooler group. In addition AL is lower in all age groups than Asian population sexcept preschooler group. With age AL increases, SE decreases and AL plays a key role in refractive development.


Asunto(s)
Cámara Anterior , Errores de Refracción , Biometría , Niño , Femenino , Humanos , Masculino , Estudios Prospectivos , Refracción Ocular , Errores de Refracción/epidemiología
2.
Niger J Clin Pract ; 24(4): 561-568, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33851679

RESUMEN

OBJECTIVES: In this study, we retrospectively evaluated the orbital and ocular dimensions using computed tomography (CT) scans in healthy adults. MATERIALS AND METHODS: This retrospective study included 302 Turkish adult individuals aged 20-76 years (158 males and 144 females), who underwent paranasal sinus or craniofacial CT due to headache or suspicion of sinusitis, but abnormal orbital or cranial CT findings were not detected. Linear and volumetric measurements of the orbital structures were performed in the sagittal, coronal, and axial planes on CT slices. The volume was estimated in cubic centimeters using the equation of the ellipsoid method. A total of 34 parameters were measured from both eyes of each individual using 14 different anatomical landmarks and analyzed by gender and age. RESULTS: Parameter values of orbital structures in males and females are shown in millimeters or cubic centimeters. In most of the 34 parameters that we evaluated, it was seen that males had statistically significant higher mean values than females (P < 0.05). Also, there was no statistically significant difference between the measurements of right and left orbits. The correlation with age was varied according to the 34 parameters. Interestingly enough, there were no statistically significant differences between the two genders for extraocular muscles thickness (except superior muscles group thickness-SMT) and left optic nerve thickness (LOT) (p > 0.05). The mean right superior muscles group thickness was 5.35 ± 0.85 mm in the male subjects and 4.64 ± 1.10 mm in the female subjects (P < 0.001). The mean left superior muscles group thickness (LSMT) was 5.28 ± 0.88 mm in the male subjects and 4.67 ± 1.16 mm in the female subjects (P < 0.001). The mean LOT was 6.15 ± 0.97 and 5.88 ± 1.07 mm in males and females, respectively (P = 0.099). CONCLUSION: This study can be applied to the standardization of orbital morphometry in healthy adults.


Asunto(s)
Órbita , Tomografía Computarizada por Rayos X , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Músculos Oculomotores/diagnóstico por imagen , Órbita/diagnóstico por imagen , Estudios Retrospectivos , Cráneo , Adulto Joven
3.
Malays J Pathol ; 38(2): 131-40, 2016 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-27568670

RESUMEN

BACKGROUND: The aim of this study was to compare the performance of Agilent 1100 HPLC analyser using HbA1c kits manufactured by Gordion Diagnostic (Turkey) with that of Premier Hb9210 using the original kits for the measurement of HbA1c in different patient groups. METHODS: Subjects were divided into four groups: Group 1 included 140 diabetic and non-diabetic subjects with normal urea and haemoglobin levels; Group 2 included 84 diabetic and non-diabetic subjects with high urea levels; Group 3 included 44 diabetic and non-diabetic subjects with iron deficiency anaemia; and Group 4 included 52 diabetic and non-diabetic subjects with high haemoglobin levels. EP Evaluator Release 8 program was used to evaluate the resultant data. RESULTS: According to the comparison results of the two methods in all groups, there was an excellent correlation between the two methods (R>0.98). Moderate-low correlation was found between increased urea concentration and the difference of the two methods (R= -0.374, p = 0.0005). The difference between the methods was found to be increased with increased urea concentrations. This difference, although statistically significant, was within the permitted limits. The observed correlation between the difference of the two methods and the low and high haemoglobin concentrations was statistically non-significant (R = 0.149, p = 0.3343; R = 0.263, p = 0.0594). CONCLUSIONS: We found that Agilent 1100 HbA1c analyser and Gordions' HbA1c kit comply with the clinical requirements and are suitable for HbA1c analysis at high levels of urea and Hb and low levels of Hb in diabetic and non-diabetic patients.


Asunto(s)
Cromatografía de Afinidad/métodos , Cromatografía Líquida de Alta Presión/métodos , Cromatografía por Intercambio Iónico/métodos , Hemoglobina Glucada/análisis , Diabetes Mellitus/sangre , Femenino , Humanos , Masculino , Reproducibilidad de los Resultados
4.
Niger J Clin Pract ; 18(6): 731-8, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26289509

RESUMEN

PURPOSE: The aim of this study was to analyze the clinical and radiological features of supernumerary teeth (ST), record the related complications, and discuss different forms of treatment. MATERIALS AND METHODS: A total of 111,293 patients were examined over a 3-year period. The patients' ages and genders, in addition to the number, morphology, location, position, shape, developmental stage, and eruption status of ST and associated complications, were recorded. RESULTS: Among the 111,293 patients, there were 851 (0.76%) patients with 1100 ST. Of these patients, 478 (56.2%) were males, and 373 (43.8%) were females, with a mean age of 22.71. Most of the 1100 ST were located in the maxilla, 437 (39.72%) were a conical shape, with 82.81% of these including a fully developed tooth. A mesiodens was the most common type of supernumerary tooth (n=284, 33.37%), followed by distomolars (n=204, 23.97%) and parapremolars (n=146, 17.16%). Among the 1100 ST, 422 (38.36%) were associated with complications. CONCLUSIONS: No previous studies in the literature have examined in detail so many cases with ST. The demographic profile of the patients with ST presented herein provides useful additional epidemiological information.


Asunto(s)
Maxilar/patología , Erupción Dental , Diente Supernumerario/epidemiología , Adolescente , Adulto , Anciano , Niño , Preescolar , Femenino , Humanos , Masculino , Persona de Mediana Edad , Prevalencia , Estudios Retrospectivos , Diente Supernumerario/diagnóstico , Turquía/epidemiología , Adulto Joven
5.
Niger J Clin Pract ; 18(6): 739-43, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26289510

RESUMEN

OBJECTIVE: The objective of this study was to evaluate the tissue inflammation caused by three endodontic repair materials. MATERIALS AND METHODS: The materials included micro mega-mineral trioxide aggregate (MM-MTA), bioaggregate (BA), and biodentine (BD), which were implanted into the subcutaneous tissue of rats. The tissue samples for histological examination were prepared. The infiltration of lymphocytes and macrophages into the tissue was examined to assess the inflammatory response. RESULTS: Lymphocyte infiltration: A significant increase was detected in the MM-MTA and BA groups on the 7th and 14th days as compared with the control (7th day P=0.0001, 14th day P=0.0176). There was no difference between the groups on the 45th day (P=0.1730). Lymphocyte infiltration had decreased over time in all groups. Macrophage infiltration: There was a significant increase by the 7th day in the test groups as compared to the control group (P=0.007). However, there was no difference between the experimental groups on the 14th (P=0.2708) and 45th (P=0.1291) days. CONCLUSION: While MM-MTA and BA showed a similar biocompatibility, BD was more biocompatible than MM-MTA and BA in the 1 st week of the experiment. However, there was no difference between the materials at the end of the 45th day. MM-MTA, BA, and BD can be considered suitable endodontic repair materials.


Asunto(s)
Compuestos de Aluminio/farmacología , Compuestos de Calcio/farmacología , Hidróxido de Calcio/farmacología , Hidroxiapatitas/farmacología , Ensayo de Materiales/métodos , Óxidos/farmacología , Silicatos/farmacología , Tejido Subcutáneo/efectos de los fármacos , Animales , Combinación de Medicamentos , Femenino , Materiales de Recubrimiento Pulpar y Pulpectomía , Ratas , Ratas Wistar , Materiales de Obturación del Conducto Radicular
6.
Niger J Clin Pract ; 18(6): 726-30, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26289508

RESUMEN

OBJECTIVE: The purpose of this study was to analyze clinic and radiologic features of the 69 odontoma cases and present a rare case of erupted compound odontoma in the oral cavity. MATERIAL AND METHODS: The 69 cases were analyzed with regard to the following parameters: age, gender, location, associated unerupted teeth, missing teeth, radiological and histopathological features and treatment protocols. RESULTS: Of the 69 cases, 49 were compound odontoma and 20 were complex odontoma. There was a female predilection for both compound and complex odontomas. Compound odontoma occurred more often in the anterior region of the jaws; complex lesions occurred more often at the posterior mandible. The most common clinical manifestations were the retention of permanent teeth. CONCLUSION: Compound odontomas rarely erupt into the mouth. The presented case is the 13 th case of erupted compound odontoma reported in the literature. The treatment of choice is surgical removal of the odontoma. In the case of odontomas associated to impacted teeth, the teeth should be preserved in wait of spontaneous eruption, or alternatively fenestration followed by orthodontic traction is indicated. Regular follow-up period is crucial to evaluate the prognosis of these teeth.


Asunto(s)
Neoplasias Mandibulares/complicaciones , Odontoma/complicaciones , Diente Primario/patología , Diente Impactado/etiología , Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Masculino , Neoplasias Mandibulares/diagnóstico , Persona de Mediana Edad , Odontoma/diagnóstico , Pronóstico , Estudios Retrospectivos , Diente Impactado/diagnóstico , Diente Impactado/cirugía , Adulto Joven
7.
Orthod Craniofac Res ; 17(3): 170-7, 2014 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-24703091

RESUMEN

OBJECTIVES: To evaluate and compare the shear bond strength (SBS) of stainless steel and gold-plated attachments to impacted lower third molars in vivo and in vitro with a light-cured orthodontic resin. SETTING AND SAMPLE POPULATION: Sixteen patients with bilaterally full soft tissue impaction of lower third molars were recruited on a voluntary basis from an oral and maxillofacial surgery department. MATERIALS AND METHODS: A split-arch technique was used. Following surgical exposure of the crown, the tooth was luxated but not extracted. Then, two attachments (one stainless steel button and one gold-plated eyelet) were bonded to the labial enamel surface of the loosened tooth. Five minutes later, the luxated tooth was removed from its socket. In each patient, the impacted tooth on the other side was extracted, and attachments were bonded in vitro. The SBSs of the attachments were evaluated. For comparison, analysis of variance and multiple range tests were used (α = 0.05). RESULTS: Statistically significant differences were evident in attachment adhesion to the impacted tooth surfaces among the four groups (p < 0.001). Superior SBS values were obtained for stainless steel button groups bonded in vitro. The mean bond strengths of the groups bonded in vitro were better than those of the same groups bonded in vivo. CONCLUSIONS: Although the in vitro-bonded groups showed higher SBS values, adequate bond strength is possible with stainless steel buttons bonded in vivo.


Asunto(s)
Recubrimiento Dental Adhesivo , Diseño de Aparato Ortodóncico , Aparatos Ortodóncicos , Extrusión Ortodóncica/instrumentación , Diente Impactado/patología , Adolescente , Adulto , Análisis del Estrés Dental/instrumentación , Aleaciones de Oro/química , Humanos , Ensayo de Materiales , Tercer Molar/patología , Tercer Molar/cirugía , Cementos de Resina/química , Resistencia al Corte , Acero Inoxidable/química , Estrés Mecánico , Extracción Dental , Diente Impactado/cirugía , Adulto Joven
8.
Eur Rev Med Pharmacol Sci ; 28(8): 3165-3175, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38708475

RESUMEN

OBJECTIVE: Periprosthetic fractures following total knee replacement are rare but challenging. The goal of the treatment is to achieve the most stable fixation that allows early mobilization. Therefore, the aim of this study was to evaluate the biomechanical results of the use of different fixation systems in the treatment of distal femur periprosthetic fractures with finite element analysis. MATERIALS AND METHODS: A total knee prosthesis was implanted in Sawbone femur models. A transverse fracture line was created in the supracondylar region and was fixed in four different groups. In group 1, fracture line fixation was fixed using retrograde intramedullary nailing. In group 2, fixation was applied using a lateral anatomic distal femoral. In group 3, in addition to the fixation made in group 1, a lateral anatomic distal femoral plate was used. In group 4, in addition to the fixation made in group 2, a 3.5 mm Limited Contact Dynamic Compression Plate (LC-DCP) was applied medially. Computed Tomography (CT) scans were taken of the created models and were converted to three-dimensional models. Axial and rotational loading forces were applied to all the created models. RESULTS: The least deformation with axial loading was observed in the double plate group. Group 3 was determined to be more advantageous against rotational forces. The greatest movement in the fracture line was found in group 2. The application of the medial plate was determined to reduce the tension on the lateral plate and increase stability in the fracture line. CONCLUSIONS: Combining a lateral anatomic plate with intramedullary nailing or a medial plate was seen to be biomechanically more advantageous than using a lateral plate or intramedullary nailing alone in the treatment of distal femoral periprosthetic fractures.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Clavos Ortopédicos , Placas Óseas , Fracturas del Fémur , Análisis de Elementos Finitos , Fijación Intramedular de Fracturas , Fracturas Periprotésicas , Artroplastia de Reemplazo de Rodilla/efectos adversos , Fracturas del Fémur/cirugía , Humanos , Fracturas Periprotésicas/cirugía , Fijación Intramedular de Fracturas/instrumentación , Tornillos Óseos , Fenómenos Biomecánicos
9.
Eur Rev Med Pharmacol Sci ; 27(23): 11315-11322, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38095380

RESUMEN

OBJECTIVE: Pulmonary hypertension (PH) is a rare heart disease associated with high maternal and fetal mortality. This study aims to discuss anesthesia management and the fetal and maternal outcomes of patients with PH followed-up at our clinic. PATIENTS AND METHODS: This study includes a retrospective analysis of 105 pregnant women with PH. The patients were classified according to the mean pulmonary artery pressure (mPAP) values measured at rest by transthoracic echocardiography. The first group included patients with an mPAP value between 25 and 49 mmHg, considered to have a mild PH, whereas patients with an mPAB value ≥50 mmHg were considered to have severe PH and were included in the second group. RESULTS: When the patients were examined for etiology, the majority (n=84, 70.5%) were found to have type 2 PH. It was found that in pregnant women with severe PH, the diameters of the left atrium, right atrium, and right ventricle were significantly larger (p=0.008, p=0.04, and p=0.013, respectively), and the ejection fraction was also significantly lower (p=0.04). CONCLUSIONS: Although there has been a partial decrease in mortality for PH in recent years, it is still a serious condition that requires a multidisciplinary approach and well-planned obstetric treatment.


Asunto(s)
Anestesia , Hipertensión Pulmonar , Embarazo , Humanos , Femenino , Mujeres Embarazadas , Estudios Retrospectivos , Ecocardiografía
10.
Actas Urol Esp (Engl Ed) ; 45(2): 132-138, 2021 Mar.
Artículo en Inglés, Español | MEDLINE | ID: mdl-33162206

RESUMEN

OBJECTIVE: To evaluate the accuracy of the Dogan nomogram in predicting stone-free (SF) rate after a single shock wave lithotripsy (SWL) session and evaluate factors that predict SWL results in children. PATIENTS AND METHODS: The study included 68 patients under 18 years of age who had been treated with SWL for radiopaque upper urinary tract stones in our tertiary centre from January 2010 to December 2016. The median age is 50 (6-207) months and median follow-up period is 9 (4-50) months. Patients with known cystine stone disease, abnormal renal anatomy, urinary diversion and multiple stones located in different calyces were excluded like in the original nomogram study. SF status was evaluated by performing plain abdominal radiography and urinary ultrasonography 2 weeks after each SWL session. Patients who were completely free of stones were considered to be SF. Multiple logistic regression analyses were performed to determine the variables affecting SF status. The bootstrap method with 1,000 replicates was used for the external validity of a nomogram developed by Dogan. RESULTS: SF rates for each SWL session were determined as 54.4% (37/68) for the first session, 33.3% (7/21) for the second session and 55.6% (5/9) for the third session. Overall, the SF rate was 72.1% (49/68). Multiple logistic regression analysis showed positive and significant correlations of age and stone size with risk of SWL failure. The external calibration plot showed a nearly good validation with Dogan nomogram to predict SWL failure in first session. CONCLUSION: Our study demonstrates that the Dogan nomogram can be used to predict the SF status after one session of SWL in pediatric patients.


Asunto(s)
Litotricia , Nomogramas , Cálculos Urinarios/terapia , Adolescente , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Pronóstico , Estudios Retrospectivos
11.
Eur J Paediatr Dent ; 11(3): 149-52, 2010 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-21080757

RESUMEN

AIM: The purpose of this article is to report the clinical course of a 12-year-old child with ectodermal dysplasia who was treated with an implant-supported overdenture for the mandible and an overdenture for the maxilla. CASE REPORT: Two dental implants were placed in the canine regions of the mandible. The maxillary teeth were prepared for the milled copings. Because the preparation of parallel walls was difficult, near-parallelism with an angle of convergence or taper of approximately 5 degrees was achieved. The cervical third of the teeth was prepared to be as parallel as possible to one another. In addition, the occlusal surfaces were reduced 1.5 mm, and the axial surfaces were reduced 1 mm. Occlusal reduction was performed to provide adequate thickness for the overlying denture base material. A chamfer finish line was prepared. The copings were cast with a Cr-Ni-based metal alloy and luted, bilateral balanced occlusion was developed using anatomic acrylic teeth. An impression was taken with an individual tray for impressions of overdentures. In response to the patient's dry mucosa, the impressions were taken using rapid-setting silicone impression material with high elasticity. Bilateral balanced occlusion was achieved using anatomic acrylic teeth for overdentures. The maxillary overdenture and implant-supported mandibular overdenture were prepared by conventional methods using thermal-curing acrylic resin. The patient was seen 48 hours later for adjustment, then after 1 and 2 weeks, 1, 3, and 6 months, and 1 year and he is still satisfied with his prosthesis both aesthetically and functionally. CONCLUSION: The use of endosseous implants in the prosthetic rehabilitation of children with ectodermal dysplasia may provide a considerable improvement in comparison with traditional prosthetic methods.


Asunto(s)
Anodoncia/rehabilitación , Prótesis Dental de Soporte Implantado , Prótesis de Recubrimiento , Displasia Ectodérmica Hipohidrótica Autosómica Recesiva/complicaciones , Anodoncia/etiología , Niño , Implantación Dental Endoósea , Humanos , Masculino
12.
Physiol Int ; 106(2): 151-157, 2019 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-31262207

RESUMEN

The medial olivocochlear efferent (MOCE) branch synapses with outer hair cells (OHCs), and the efferent pathway can be activated via a contralateral acoustic stimulus (CAS). The activation of MOCE can change OHC motile responses and convert signals that are capable of controlling the sensitivity of the peripheral hearing system in a frequency-specific manner. The aim of this study was to examine the MOCE system activity in professional musicians using transient evoked otoacoustic emission test and CAS. Musician group showed stronger suppression in all frequency bands in the presence of CAS.


Asunto(s)
Cóclea/fisiología , Núcleo Olivar/fisiología , Estimulación Acústica/métodos , Adulto , Vías Auditivas/fisiología , Vías Eferentes/fisiología , Femenino , Audición/fisiología , Humanos , Masculino , Persona de Mediana Edad , Música , Emisiones Otoacústicas Espontáneas/fisiología , Adulto Joven
13.
AJNR Am J Neuroradiol ; 40(4): 726-731, 2019 04.
Artículo en Inglés | MEDLINE | ID: mdl-30846436

RESUMEN

BACKGROUND AND PURPOSE: Differentiating pediatric-onset neuromyelitis optica spectrum disorder from acute disseminated encephalomyelitis could be challenging, especially in cases presenting with only brain manifestations. Our purpose was to investigate brain MR imaging features that may help distinguish these 2 entities. MATERIALS AND METHODS: We retrospectively examined initial brain MR imaging studies of 10 patients with pediatric-onset neuromyelitis optica spectrum disorder (female/male ratio, 7:3) and 10 patients with acute disseminated encephalomyelitis (female/male ratio, 2:8). The mean age of the patients was 10.3 ± 5.6 and 8.7 ± 5.3 years, respectively. Brain lesions were evaluated with respect to location, extent, expansion, T1 hypointensity, contrast enhancement/pattern, and diffusion characteristics. The χ2 test (Yates or Fisher exact χ2tests) was used to compare differences between groups. RESULTS: Cerebral subcortical ± juxtacortical and pons ± middle cerebellar peduncle were the most frequent locations involved in both neuromyelitis optica spectrum disorder (n = 5 and 4, respectively) and acute disseminated encephalomyelitis (n = 9 and 7, respectively). Thalamic lesions were more frequent in acute disseminated encephalomyelitis (P = .020) and were detected only in 1 patient with neuromyelitis optica spectrum disorder. None of the patients with neuromyelitis optica spectrum disorder had hypothalamic, internal capsule, or cortical lesions. The internal capsule involvement was found to be significantly different between groups (P = .033). There was no significant difference in terms of extent, expansion, T1 hypointensity, contrast enhancement/pattern, and diffusion characteristics. CONCLUSIONS: Although there is a considerable overlap in brain MR imaging findings, thalamic and internal capsule involvement could be used to differentiate pediatric-onset neuromyelitis optica spectrum disorder from acute disseminated encephalomyelitis.


Asunto(s)
Encefalomielitis Aguda Diseminada/diagnóstico por imagen , Neuromielitis Óptica/diagnóstico por imagen , Adolescente , Niño , Preescolar , Diagnóstico Diferencial , Encefalomielitis Aguda Diseminada/patología , Femenino , Humanos , Imagen por Resonancia Magnética/métodos , Masculino , Neuroimagen/métodos , Neuromielitis Óptica/patología , Estudios Retrospectivos
14.
AJNR Am J Neuroradiol ; 40(8): 1427-1432, 2019 08.
Artículo en Inglés | MEDLINE | ID: mdl-31296526

RESUMEN

BACKGROUND AND PURPOSE: The early prediction of recurrence after an initial event of transverse myelitis helps to guide preventive treatment and optimize outcomes. Our aim was to identify MR imaging findings predictive of relapse and poor outcome in patients with acute transverse myelitis of unidentified etiology. MATERIALS AND METHODS: Spinal MRIs of 77 patients (mean age, 36.3 ± 20 years) diagnosed with acute transverse myelitis were evaluated retrospectively. Only the patients for whom an underlying cause of myelitis could not be identified within 3 months of symptom onset were included. Initial spinal MR images of patients were examined in terms of lesion extent, location and distribution, brain stem extension, cord expansion, T1 signal, contrast enhancement, and the presence of bright spotty lesions and the owl's eyes sign. The relapse rates and Kurtzke Expanded Disability Status Scale scores at least 1 year (range, 1-14 years) after a myelitis attack were also recorded. Associations of MR imaging findings with clinical variables were studied with univariate associations and binary log-linear regression. Differences were considered significant for P values < .05. RESULTS: Twenty-seven patients (35.1%) eventually developed recurrent disease. Binary logistic regression revealed 3 main significant predictors of recurrence: cord expansion (OR, 5.30; 95% CI, 1.33-21.11), contrast enhancement (OR, 5.05; 95% CI, 1.25-20.34), and bright spotty lesions (OR, 3.63; 95% CI, 1.06-12.43). None of the imaging variables showed significant correlation with the disability scores. CONCLUSIONS: Cord expansion, contrast enhancement, and the presence of bright spotty lesions could be used as early MR imaging predictors of relapse in patients with acute transverse myelitis of unidentified etiology. Collaborative studies with a larger number of patients are required to validate these findings.


Asunto(s)
Imagen por Resonancia Magnética/métodos , Mielitis Transversa/diagnóstico por imagen , Adolescente , Adulto , Niño , Medios de Contraste , Evaluación de la Discapacidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Mielitis Transversa/etiología , Valor Predictivo de las Pruebas , Recurrencia , Estudios Retrospectivos , Resultado del Tratamiento , Adulto Joven
16.
AJNR Am J Neuroradiol ; 39(9): 1745-1750, 2018 09.
Artículo en Inglés | MEDLINE | ID: mdl-30093478

RESUMEN

BACKGROUND AND PURPOSE: Brachial plexus birth injury is caused by traction on the neck during delivery and results in flaccid palsy of an upper extremity commonly involving C5-C6 nerve roots. MR imaging and MR myelography help to assess the anatomic location, extent, and severity of brachial plexus injuries which influence the long-term prognosis along with the surgical decision making. Recently, sonography has been increasingly used as the imaging modality of choice for brachial plexus injuries. The aim of this study was to assess the degree of correlation among brachial plexus sonography, MR imaging, and surgical findings in children with brachial plexus birth injury. MATERIALS AND METHODS: This prospective study included 55 consecutive patients (girls/boys = 32:23; mean age, 2.1 ± 0.8 months) with brachial plexus birth injury between May 2014 and April 2017. The patients were classified according to the Narakas classification and were followed up at 4- to 6-week intervals for recovery by the Modified Mallet system and sonography without specific preparation for evaluation. All patients had MR imaging under general anesthesia. Nerve root avulsion-retraction, pseudomeningocele, and periscalene soft tissue were accepted brachial plexus injury findings on imaging. Interobserver agreement for MR imaging and the agreement between imaging and surgical findings were estimated using the κ statistic. The diagnostic accuracy of sonography and MR imaging was calculated on the basis of the standard reference, which was the surgical findings. RESULTS: Forty-three patients had pre- and postganglionic injury, 12 had only postganglionic injury findings, and 47% of patients underwent an operation. On sonography, no patients had preganglionic injury, but all patients had postganglionic injury findings. For postganglionic injury, the concordance rates between imaging and the surgical findings ranged from 84% to 100%, and the diagnostic accuracy of sonography and MR imaging was 89% and 100%, respectively. For preganglionic injury, the diagnostic accuracy of MR imaging was 92%. Interobserver agreement and the agreement between imaging and the surgical findings were almost perfect for postganglionic injury (κ = 0.81-1, P < .001). CONCLUSIONS: High-resolution sonography can identify and locate the postganglionic injury associated with the upper and middle trunks. The ability of sonography to evaluate pre- and the postganglionic injury associated with the lower trunk was quite limited. Sonography can be used as a complement to MR imaging; thus, the duration of the MR imaging examination and the need for sedation can be reduced by sonography.


Asunto(s)
Neuropatías del Plexo Braquial/diagnóstico por imagen , Imagen por Resonancia Magnética/métodos , Neuroimagen/métodos , Ultrasonografía/métodos , Plexo Braquial/diagnóstico por imagen , Preescolar , Femenino , Humanos , Lactante , Masculino , Pronóstico , Estudios Prospectivos
18.
Physiol Int ; 104(2): 171-182, 2017 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-28648121

RESUMEN

We hypothesized that cochlear frequency discrimination occurs through medial olivocochlear efferent (MOCE)-induced alterations in outer hair cell (OHC) electromotility, which is independent from basilar membrane traveling waves. After obtaining informed consent, volunteers with normal hearing (n = 10; mean age: 20.6 ± 1.2 years) and patients with unilateral deafness (n = 10; mean age: 30.2 ± 17.9 years) or bilateral deafness (n = 8; mean age: 30.7 ± 13.8 years) underwent a complete physical and audiological examination, and audiological tests including transient evoked otoacoustic emission and spontaneous otoacoustic emission (TEOAE and SOAE, respectively). SOAE recordings were performed during contralateral pure-tone stimuli at 1 and 3 kHz. SOAE recordings in the presence of contralateral pure-tone stimuli showed frequency-specific activation out of the initial frequency range of SOAE responses. Basilar membrane motion during pure-tone stimulation results from OHC activation by means of MOCE neurons rather than from a traveling wave. Eventually, frequency-specific responses obtained from SOAEs suggested that OHC electromotility may be responsible for frequency discrimination of the cochlea independently from basilar membrane motion.


Asunto(s)
Estimulación Acústica/métodos , Vías Auditivas/fisiología , Cóclea/fisiología , Emisiones Otoacústicas Espontáneas/fisiología , Percepción de la Altura Tonal/fisiología , Reflejo Acústico/fisiología , Complejo Olivar Superior/fisiología , Cóclea/inervación , Femenino , Humanos , Masculino , Adulto Joven
19.
J Oral Sci ; 43(2): 117-22, 2001 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-11515595

RESUMEN

Postoperative infections in the oral region are usually caused by anaerobic bacteria. While some authors claim that routine antibiotic prophylaxis is necessary after third molar surgery, others do not recommend this practice. The major subject of controversy is what constitutes postoperative infection. Previous studies that have examined the benefit of routine antibiotic prophylaxis have used several clinical symptoms (pain, swelling, and trismus) as indicators of infection; however, these clinical symptoms may be vague and unreliable, and cannot be evaluated scientifically. As a result, their use has only sparked more debate in this area of research. The present study assessed the value of routine antibiotic prophylaxis in impacted mandibular third molar surgery using acute-phase protein levels as potential indicators of early and late postoperative infection. Specifically, serum levels of C-reactive protein and alpha-1 antitrypsin were measured preoperatively and postoperatively in patients who received either prophylactic antibiotics or placebos. The results revealed no statistically significant difference between treated and control patients in terms of incidence of postoperative infection.


Asunto(s)
Proteínas de Fase Aguda/análisis , Profilaxis Antibiótica , Mandíbula/cirugía , Tercer Molar/cirugía , Infección de la Herida Quirúrgica/diagnóstico , Diente Impactado/cirugía , Acetaminofén/uso terapéutico , Adulto , Amoxicilina/uso terapéutico , Analgésicos no Narcóticos/uso terapéutico , Antibacterianos/uso terapéutico , Biomarcadores/análisis , Biomarcadores/sangre , Proteína C-Reactiva/análisis , Clindamicina/uso terapéutico , Estudios Cruzados , Método Doble Ciego , Femenino , Humanos , Masculino , Penicilinas/uso terapéutico , Placebos , Estadística como Asunto , Infección de la Herida Quirúrgica/prevención & control , Factores de Tiempo , alfa 1-Antitripsina/análisis
20.
J Oral Sci ; 43(4): 283-6, 2001 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-11848196

RESUMEN

Adenomatoid odontogenic tumors are uncommon odontogenic lesions characterized by duct-like structures that form from the epithelial component of the lesion. Most of these masses develop in the second or third decade of life, and there is a strong female bias in occurrence. Typically, these lesions arise in the lateral incisor/canine region of the maxilla, where they produce a swelling. Only in very rare cases is the lesion found distal to the premolar area. Nearly all of these growths are associated with an embedded anterior maxillary tooth (usually a canine), and most resemble a 1-3 cm diameter dentigerous cyst. Radiopacity is reported in two-thirds of cases. This article describes the case of a 9-year-old Caucasian male who presented with a painless swelling in the left premolar-molar region of his maxilla. This case is of particular interest because the features (patient age, gender, lesion location, size, and radiographic findings) were not typical of adenomatoid odontogenic tumor.


Asunto(s)
Neoplasias Maxilares/patología , Tumores Odontogénicos/patología , Diente Premolar/patología , Biopsia , Calcinosis/patología , Niño , Diagnóstico Diferencial , Células Epiteliales/patología , Humanos , Masculino , Diente Molar/patología , Radiografía Panorámica , Tomografía Computarizada por Rayos X
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA