1.
J Nat Prod
; 69(6): 980-2, 2006 Jun.
Artículo
en Inglés
| MEDLINE
| ID: mdl-16792425
RESUMEN
Five new chromones, named lachnones A-E (1-5), were isolated from the filamentous fungus Lachnum sp. BCC 2424 along with known (2E,6S)-2,6-dimethyl-2,7-octadiene-1,6-diol. Their structures were elucidated by spectroscopic methods. Lachnones B (2) and D (4) mildly inhibited the growth of Mycobacterium tuberculosis, both with MIC values of 200 microg/mL.
Asunto(s)
Antituberculosos/aislamiento & purificación , Ascomicetos/química , Cromonas/aislamiento & purificación , Mycobacterium tuberculosis/efectos de los fármacos , Antituberculosos/química , Antituberculosos/farmacología , Cromonas/química , Cromonas/farmacología , Pruebas de Sensibilidad Microbiana , Estructura Molecular , Resonancia Magnética Nuclear Biomolecular , Tailandia
2.
J Nat Prod
; 69(2): 305-7, 2006 Feb.
Artículo
en Inglés
| MEDLINE
| ID: mdl-16499340
RESUMEN
A new cycloheptapeptide, cordyheptapeptide A (1), was isolated from the insect pathogenic fungus Cordyceps sp. BCC 1788 along with four known bioxanthracenes (2-5). The structure was elucidated by spectroscopic data. The absolute configuration of amino acid residues was determined by HPLC and X-ray diffraction analyses.