Detalles de la búsqueda
1.
Safety and Pharmacokinetics of Islatravir in Individuals with Severe Renal Insufficiency.
Antimicrob Agents Chemother
; 66(12): e0093122, 2022 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-36346229
2.
Pharmacokinetic Interactions between the Hepatitis C Virus Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, and Darunavir in Healthy Volunteers.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30745392
3.
Rhinovirus-16 induced temporal interferon responses in nasal epithelium links with viral clearance and symptoms.
Clin Exp Allergy
; 49(12): 1587-1597, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31400236
4.
Characterization of the novel GlyT1 PET tracer [18F]MK-6577 in humans.
Synapse
; 69(1): 33-40, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25196464
5.
Characterizing the PK/PD relationship for inhibition of capsaicin-induced dermal vasodilatation by MK-3207, an oral calcitonin gene related peptide receptor antagonist.
Br J Clin Pharmacol
; 79(5): 831-7, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25377933
6.
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake.
Cell Metab
; 7(1): 68-78, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18177726
7.
Evaluation of [¹8F]MK-0911, a positron emission tomography (PET) tracer for opioid receptor-like 1 (ORL1), in rhesus monkey and human.
Neuroimage
; 68: 1-10, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23238431
8.
In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C]MK-4232.
J Pharmacol Exp Ther
; 347(2): 478-86, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23975906
9.
A randomized clinical trial comparing point-of-care platelet function assays and bleeding time in healthy subjects treated with aspirin or clopidogrel.
Platelets
; 23(4): 249-58, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-21919555
10.
Single Oral Doses of MK-8507, a Novel Non-Nucleoside Reverse Transcriptase Inhibitor, Suppress HIV-1 RNA for a Week.
J Acquir Immune Defic Syndr
; 89(2): 191-198, 2022 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34654041
11.
The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease.
Sci Transl Med
; 14(627): eabg3684, 2022 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35020407
12.
The potent calcitonin gene-related peptide receptor antagonist, telcagepant, does not affect nitroglycerin-induced vasodilation in healthy men.
Br J Clin Pharmacol
; 71(5): 708-17, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21480950
13.
The effects of laropiprant, a selective prostaglandin D2 receptor 1 antagonist, on the antiplatelet activity of clopidogrel or aspirin.
Platelets
; 22(7): 495-503, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21526889
14.
Safety, tolerability, and pharmacokinetics of single- and multiple-dose administration of islatravir (MK-8591) in adults without HIV.
Clin Transl Sci
; 14(5): 1935-1944, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34463432
15.
Kinetic analysis of the cannabinoid-1 receptor PET tracer [(18)F]MK-9470 in human brain.
Eur J Nucl Med Mol Imaging
; 37(5): 920-33, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20033684
16.
Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974).
Br J Clin Pharmacol
; 69(1): 15-22, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20078608
17.
Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial.
Lancet HIV
; 7(3): e164-e172, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31911147
18.
Whole-body biodistribution and radiation dosimetry of the human cannabinoid type-1 receptor ligand 18F-MK-9470 in healthy subjects.
J Nucl Med
; 49(3): 439-45, 2008 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18287275
19.
Multiple-dose pharmacokinetics, pharmacodynamics, and safety of taranabant, a novel selective cannabinoid-1 receptor inverse agonist, in healthy male volunteers.
J Clin Pharmacol
; 48(6): 734-44, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18508950
20.
Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.
J Clin Endocrinol Metab
; 91(11): 4612-9, 2006 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16912128