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1.
Discovery of novel benzohydroxamate-based histone deacetylase 6 (HDAC6) inhibitors with the ability to potentiate anti-PD-L1 immunotherapy in melanoma.
J Enzyme Inhib Med Chem
; 38(1): 2201408, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37096557
2.
Design, synthesis, and bioevaluation of imidazo [1,2-a] pyrazine derivatives as tubulin polymerization inhibitors with potent anticancer activities.
Bioorg Med Chem
; 76: 117098, 2022 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36455508
3.
Design, Synthesis, and Bioevaluation of Novel Enzyme-Triggerable Cell Penetrating Peptide-Based Dendrimers for Targeted Delivery of Camptothecin and Cancer Therapy.
J Med Chem
; 65(7): 5850-5865, 2022 04 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35380045
4.
Discovery of pomalidomide-based PROTACs for selective degradation of histone deacetylase 8.
Eur J Med Chem
; 239: 114544, 2022 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35759908
5.
Discovery of Thieno[2,3-d]pyrimidine-based KRAS G12D inhibitors as potential anticancer agents via combinatorial virtual screening.
Eur J Med Chem
; 233: 114243, 2022 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35276423
6.
Novel CRBN-Recruiting Proteolysis-Targeting Chimeras as Degraders of Stimulator of Interferon Genes with In Vivo Anti-Inflammatory Efficacy.
J Med Chem
; 65(9): 6593-6611, 2022 05 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35452223
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