RESUMEN
Argyrophilie technique to identify nucleolar organizer regions (NORs) applied in formalin-fixed paraffin sections of thyroid tissue allow us to reveal NORs as block dots in the nuclei of cells. In the present study the relationship between number of NORs and cellular activation emphasize significant statistical data: it was found that the number of AgNORs in malignant thyroid lesions significantly exceeded those of benign thyroid lesions. This objective assessment associated with easily method show an advantage in thyroid diagnostic histopathology an adjunct to routine methods.
Asunto(s)
Región Organizadora del Nucléolo/patología , Neoplasias de la Tiroides/patología , Humanos , Pronóstico , Tinción con Nitrato de PlataRESUMEN
A new case of subcutaneous Human Dirofilariasis, in a 42-year-old woman from the province of Cosenza, is described. It is the first reported in Calabria. The nematode, an immature female of Dirofilaria repens, was clinically diagnosed as a "Fibrolipoma". In a collateral research on dogs in different areas of the same province, microfilariae of D. repens in 2 out 134 individuals were detected.
Asunto(s)
Dirofilariasis/parasitología , Adulto , Animales , Dirofilaria/anatomía & histología , Dirofilariasis/epidemiología , Femenino , Humanos , Italia/epidemiologíaRESUMEN
In non-specific and rheumatoid synovitis, the use of specific monoclonal antibodies against antigenic determinants of cells of the immune system showed that the characteristic changes of rheumatoid synovitis are located in the synovial internal layers. The monocytes were OKM1, OKM5, S100, OKDR positive, while the subintimal monocytes in non-specific synovitis were OKDR negative. We suggest that, in rheumatoid synovitis, the previously activated monocytes are transported by the bloodstream and pass through the so-called "sinovial barrier" to arrive in the subintimal layers ready to interact with T helper lymphocytes and initiate the immune response mechanisms responsible for lesions in rheumatoid synovitis.