Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.

Lynch, Caitlin; Sakamuru, Srilatha; Ooka, Masato; Huang, Ruili; Klumpp-Thomas, Carleen; Shinn, Paul; Gerhold, David; Rossoshek, Anna; Michael, Sam; Casey, Warren; Santillo, Michael F; Fitzpatrick, Suzanne; Thomas, Russell S; Simeonov, Anton; Xia, Menghang.

Annu Rev Pharmacol Toxicol ; 64: 191-209, 2024 Jan 23.

Artículo en Inglés | MEDLINE | ID: mdl-37506331

2.

Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species.

Tawa, Gregory J; Braisted, John; Gerhold, David; Grewal, Gurmit; Mazcko, Christina; Breen, Matthew; Sittampalam, Gurusingham; LeBlanc, Amy K.

PLoS Comput Biol ; 17(9): e1009450, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-34570764

3.

Stem Cell-Derived Endothelial Cell Model that Responds to Tobacco Smoke Like Primary Endothelial Cells.

Chu, Pei-Hsuan; Chen, Guibin; Kuo, David; Braisted, John; Huang, Ruili; Wang, Yuhong; Simeonov, Anton; Boehm, Manfred; Gerhold, David L.

Chem Res Toxicol ; 33(3): 751-763, 2020 03 16.

Artículo en Inglés | MEDLINE | ID: mdl-32119531

4.

The Toxmatrix: Chemo-Genomic Profiling Identifies Interactions That Reveal Mechanisms of Toxicity.

Tong, Zhi-Bin; Huang, Ruili; Wang, Yuhong; Klumpp-Thomas, Carleen A; Braisted, John C; Itkin, Zina; Shinn, Paul; Xia, Menghang; Simeonov, Anton; Gerhold, David L.

Chem Res Toxicol ; 31(2): 127-136, 2018 02 19.

Artículo en Inglés | MEDLINE | ID: mdl-29156121

5.

Characterization of three human cell line models for high-throughput neuronal cytotoxicity screening.

Tong, Zhi-Bin; Hogberg, Helena; Kuo, David; Sakamuru, Srilatha; Xia, Menghang; Smirnova, Lena; Hartung, Thomas; Gerhold, David.

J Appl Toxicol ; 37(2): 167-180, 2017 02.

Artículo en Inglés | MEDLINE | ID: mdl-27143523

6.

3D-Suspension culture platform for high throughput screening of neurotoxic chemicals using LUHMES dopaminergic neurons.

Tong, Zhi-Bin; Huang, Ruili; Braisted, John; Chu, Pei-Hsuan; Simeonov, Anton; Gerhold, David L.

SLAS Discov ; 29(3): 100143, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38280460

7.

Better therapeutics through microarrays.

Gerhold, David L; Jensen, Roderick V; Gullans, Steven R.

Nat Genet ; 32 Suppl: 547-51, 2002 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-12454652

8.

Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational value for humans.

Mannheimer, Joshua D; Tawa, Gregory; Gerhold, David; Braisted, John; Sayers, Carly M; McEachron, Troy A; Meltzer, Paul; Mazcko, Christina; Beck, Jessica A; LeBlanc, Amy K.

Commun Biol ; 6(1): 856, 2023 08 17.

Artículo en Inglés | MEDLINE | ID: mdl-37591946

9.

LUHMES Dopaminergic Neurons Are Uniquely Susceptible to Ferroptosis.

Tong, Zhi-Bin; Kim, Hyunhee; El Touny, Lara; Simeonov, Anton; Gerhold, David.

Neurotox Res ; 40(5): 1526-1536, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-35922689

10.

Universal Toxicity Gene Signatures for Early Identification of Drug-Induced Tissue Injuries in Rats.

Glaab, Warren E; Holder, Daniel; He, Yudong D; Bailey, Wendy J; Gerhold, David L; Beare, Carolann; Erdos, Zoltan; Lane, Pamela; Michna, Laura; Muniappa, Nagaraja; Lawrence, Jeffrey W; Tanis, Keith Q; Sina, Joseph F; Skopek, Thomas R; Sistare, Frank D.

Toxicol Sci ; 181(2): 148-159, 2021 05 27.

Artículo en Inglés | MEDLINE | ID: mdl-33837425

11.

The MT1G Gene in LUHMES Neurons Is a Sensitive Biomarker of Neurotoxicity.

Tong, Zhi-Bin; Braisted, John; Chu, Pei-Hsuan; Gerhold, David.

Neurotox Res ; 38(4): 967-978, 2020 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-32870474

12.

Phospholipidosis assay in HepG2 cells and rat or rhesus hepatocytes using phospholipid probe NBD-PE.

Bhandari, Neetesh; Figueroa, David J; Lawrence, Jeffrey W; Gerhold, David Lee.

Assay Drug Dev Technol ; 6(3): 407-19, 2008 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-18537465

13.

A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics.

Mav, Deepak; Shah, Ruchir R; Howard, Brian E; Auerbach, Scott S; Bushel, Pierre R; Collins, Jennifer B; Gerhold, David L; Judson, Richard S; Karmaus, Agnes L; Maull, Elizabeth A; Mendrick, Donna L; Merrick, B Alex; Sipes, Nisha S; Svoboda, Daniel; Paules, Richard S.

PLoS One ; 13(2): e0191105, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-29462216

14.

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies.

Xia, Menghang; Huang, Ruili; Shi, Qiang; Boyd, Windy A; Zhao, Jinghua; Sun, Nuo; Rice, Julie R; Dunlap, Paul E; Hackstadt, Amber J; Bridge, Matt F; Smith, Marjolein V; Dai, Sheng; Zheng, Wei; Chu, Pei-Hsuan; Gerhold, David; Witt, Kristine L; DeVito, Michael; Freedman, Jonathan H; Austin, Christopher P; Houck, Keith A; Thomas, Russell S; Paules, Richard S; Tice, Raymond R; Simeonov, Anton.

Environ Health Perspect ; 126(7): 077010, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-30059008

15.

Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles.

Jiang, Ying; Gerhold, David L; Holder, Daniel J; Figueroa, David J; Bailey, Wendy J; Guan, Ping; Skopek, Thomas R; Sistare, Frank D; Sina, Joseph F.

J Transl Med ; 5: 47, 2007 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-17908307

16.

Correction to: LUHMES Dopaminergic Neurons are Uniquely Susceptible to Ferroptosis.

Tong, Zhi-Bin; Kim, Hyunhee; El Touny, Lara; Simeonov, Anton; Gerhold, David.

Neurotox Res ; 40(5): 1537-1538, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-36029455

17.

Good Cell Culture Practice for stem cells and stem-cell-derived models.

Pamies, David; Bal-Price, Anna; Simeonov, Anton; Tagle, Danilo; Allen, Dave; Gerhold, David; Yin, Dezhong; Pistollato, Francesca; Inutsuka, Takashi; Sullivan, Kristie; Stacey, Glyn; Salem, Harry; Leist, Marcel; Daneshian, Mardas; Vemuri, Mohan C; McFarland, Richard; Coecke, Sandra; Fitzpatrick, Suzanne C; Lakshmipathy, Uma; Mack, Amanda; Wang, Wen Bo; Yamazaki, Daiju; Sekino, Yuko; Kanda, Yasunari; Smirnova, Lena; Hartung, Thomas.

ALTEX ; 34(1): 95-132, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-27554434

18.

A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives.

Grimm, Fabian A; Iwata, Yasuhiro; Sirenko, Oksana; Chappell, Grace A; Wright, Fred A; Reif, David M; Braisted, John; Gerhold, David L; Yeakley, Joanne M; Shepard, Peter; Seligmann, Bruce; Roy, Tim; Boogaard, Peter J; Ketelslegers, Hans B; Rohde, Arlean M; Rusyn, Ivan.

Green Chem ; 18(16): 4407-4419, 2016 Aug 21.

Artículo en Inglés | MEDLINE | ID: mdl-28035192

19.

Androgenic induction of growth and differentiation in the rodent uterus involves the modulation of estrogen-regulated genetic pathways.

Nantermet, Pascale V; Masarachia, Patricia; Gentile, Michael A; Pennypacker, Brenda; Xu, Jian; Holder, Daniel; Gerhold, David; Towler, Dwight; Schmidt, Azriel; Kimmel, Donald B; Freedman, Leonard P; Harada, Shun-ichi; Ray, William J.

Endocrinology ; 146(2): 564-78, 2005 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-15498879

20.

Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.

Hoeng, Julia C; Höng, Julia C; Ivanov, Nikolai V; Hodor, Paul; Xia, Menghang; Wei, Nan; Blevins, Richard; Gerhold, David; Borodovsky, Mark; Liu, Yuan.

J Mol Biol ; 337(2): 307-17, 2004 Mar 19.

Artículo en Inglés | MEDLINE | ID: mdl-15003449

Biblioteca Virtual en Salud Fronteriza

México - Estados Unidos

Su selección (0)

Formato de exportación:

Exportar: