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Transplant Proc ; 49(4): 874-877, 2017 May.
Artículo en Inglés | MEDLINE | ID: mdl-28457415

RESUMEN

OBJECTIVE: The aim of this work was to verify the association between clinical and nutritional factors and mortality in the 1st 30 days after heart transplantation. METHODS: This was a retrospective study of patients who underwent heart transplantation in a public hospital in Brazil from January 2013 to August 2015. The clinical and nutritional factors analyzed were: body mass index, body surface area, cachexia, infection, duration of orotracheal intubation, ejection fraction, mean pulmonary pressure, Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) score, hemoglobin, and diabetes mellitus. The primary outcome was mortality in the 1st 30 days after heart transplantation, and secondary outcomes were infection, acute kidney insufficiency, and duration of orotracheal intubation. We performed chi-square test, unpaired t test, and logistic regression in the analyses. A P value of < .05 was considered to be significant. RESULTS: The sample had 103 patients, of which 16 patients (15.53%) died within 30 days after heart transplantation. We observed a relationship between death and orotracheal intubation duration (P < .01), postoperative creatinine (P < .01), acute kidney injury (P < .01), and INTERMACS score (P = .01) in the bivariate analysis but not in the multivariate model. CONCLUSIONS: Clinical and nutritional factors had no impact on mortality up to 30 days after heart transplantation in this study, although orotracheal intubation duration, postoperative creatinine, acute kidney injury, and INTERMACS score were individually associated with early death.


Asunto(s)
Caquexia/mortalidad , Insuficiencia Cardíaca/cirugía , Trasplante de Corazón/mortalidad , Intubación Intratraqueal/efectos adversos , Complicaciones Posoperatorias/mortalidad , Lesión Renal Aguda/etiología , Lesión Renal Aguda/mortalidad , Lesión Renal Aguda/patología , Adulto , Anciano , Índice de Masa Corporal , Brasil , Caquexia/etiología , Caquexia/patología , Distribución de Chi-Cuadrado , Creatinina/análisis , Femenino , Humanos , Modelos Logísticos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/patología , Sistema de Registros , Estudios Retrospectivos , Volumen Sistólico , Factores de Tiempo
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