Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo.

Tang, Vi T; Xiang, Jie; Chen, Zhimin; McCormick, Joseph; Abbineni, Prabhodh S; Chen, Xiao-Wei; Hoenerhoff, Mark; Emmer, Brian T; Khoriaty, Rami; Lin, Jiandie D; Ginsburg, David.

Proc Natl Acad Sci U S A ; 121(19): e2322164121, 2024 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-38687799

2.

Genetics and genomics to the clinic: a long road ahead.

Ginsburg, David.

Cell ; 147(1): 17-9, 2011 Sep 30.

Artículo en Inglés | MEDLINE | ID: mdl-21962500

3.

Genome-scale CRISPR screening for modifiers of cellular LDL uptake.

Emmer, Brian T; Sherman, Emily J; Lascuna, Paul J; Graham, Sarah E; Willer, Cristen J; Ginsburg, David.

PLoS Genet ; 17(1): e1009285, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33513160

4.

Identification of LMAN1- and SURF4-Dependent Secretory Cargoes.

Tang, Vi T; Abbineni, Prabhodh S; Veiga Leprevost, Felipe da; Basrur, Venkatesha; Khoriaty, Rami; Emmer, Brian T; Nesvizhskii, Alexey I; Ginsburg, David.

J Proteome Res ; 22(11): 3439-3446, 2023 11 03.

Artículo en Inglés | MEDLINE | ID: mdl-37844105

5.

Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability to probe its latency transition.

Haynes, Laura M; Huttinger, Zachary M; Yee, Andrew; Kretz, Colin A; Siemieniak, David R; Lawrence, Daniel A; Ginsburg, David.

J Biol Chem ; 298(12): 102608, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36257408

6.

Tissue factor pathway inhibitor is required for cerebrovascular development in mice.

Maroney, Susan A; Westrick, Randal J; Cleuren, Audrey C; Martinez, Nicholas D; Siebert, Amy E; Zogg, Mark; Ginsburg, David; Weiler, Hartmut; Mast, Alan E.

Blood ; 137(2): 258-268, 2021 01 14.

Artículo en Inglés | MEDLINE | ID: mdl-32735640

7.

The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes.

Khan, Taslima Gani; Ginsburg, David; Emmer, Brian T.

J Lipid Res ; 63(8): 100248, 2022 08.

Artículo en Inglés | MEDLINE | ID: mdl-35753407

8.

Genome Editing and Hematologic Malignancy.

Emmer, Brian T; Ginsburg, David.

Annu Rev Med ; 71: 71-83, 2020 01 27.

Artículo en Inglés | MEDLINE | ID: mdl-31469969

9.

Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease.

Desch, Karl C; Ozel, Ayse B; Halvorsen, Matt; Jacobi, Paula M; Golden, Krista; Underwood, Mary; Germain, Marine; Tregouet, David-Alexandre; Reitsma, Pieter H; Kearon, Clive; Mokry, Lauren; Richards, J Brent; Williams, Frances; Li, Jun Z; Goldstein, David; Ginsburg, David.

Blood ; 136(5): 533-541, 2020 07 30.

Artículo en Inglés | MEDLINE | ID: mdl-32457982

10.

Identification of secreted proteins by comparison of protein abundance in conditioned media and cell lysates.

Abbineni, Prabhodh S; Tang, Vi T; da Veiga Leprevost, Felipe; Basrur, Venkatesha; Xiang, Jie; Nesvizhskii, Alexey I; Ginsburg, David.

Anal Biochem ; 655: 114846, 2022 10 15.

Artículo en Inglés | MEDLINE | ID: mdl-35973625

11.

The in vivo endothelial cell translatome is highly heterogeneous across vascular beds.

Cleuren, Audrey C A; van der Ent, Martijn A; Jiang, Hui; Hunker, Kristina L; Yee, Andrew; Siemieniak, David R; Molema, Grietje; Aird, William C; Ganesh, Santhi K; Ginsburg, David.

Proc Natl Acad Sci U S A ; 116(47): 23618-23624, 2019 11 19.

Artículo en Inglés | MEDLINE | ID: mdl-31712416

12.

Dimeric sorting code for concentrative cargo selection by the COPII coat.

Nie, Chao; Wang, Huimin; Wang, Rui; Ginsburg, David; Chen, Xiao-Wei.

Proc Natl Acad Sci U S A ; 115(14): E3155-E3162, 2018 04 03.

Artículo en Inglés | MEDLINE | ID: mdl-29555761

13.

Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse.

Tomberg, Kärt; Westrick, Randal J; Kotnik, Emilee N; Cleuren, Audrey C; Siemieniak, David R; Zhu, Guojing; Saunders, Thomas L; Ginsburg, David.

PLoS Genet ; 14(9): e1007658, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30188893

14.

Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.

Khoriaty, Rami; Hesketh, Geoffrey G; Bernard, Amélie; Weyand, Angela C; Mellacheruvu, Dattatreya; Zhu, Guojing; Hoenerhoff, Mark J; McGee, Beth; Everett, Lesley; Adams, Elizabeth J; Zhang, Bin; Saunders, Thomas L; Nesvizhskii, Alexey I; Klionsky, Daniel J; Shavit, Jordan A; Gingras, Anne-Claude; Ginsburg, David.

Proc Natl Acad Sci U S A ; 115(33): E7748-E7757, 2018 08 14.

Artículo en Inglés | MEDLINE | ID: mdl-30065114

15.

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.

van Rooij, Frank J A; Qayyum, Rehan; Smith, Albert V; Zhou, Yi; Trompet, Stella; Tanaka, Toshiko; Keller, Margaux F; Chang, Li-Ching; Schmidt, Helena; Yang, Min-Lee; Chen, Ming-Huei; Hayes, James; Johnson, Andrew D; Yanek, Lisa R; Mueller, Christian; Lange, Leslie; Floyd, James S; Ghanbari, Mohsen; Zonderman, Alan B; Jukema, J Wouter; Hofman, Albert; van Duijn, Cornelia M; Desch, Karl C; Saba, Yasaman; Ozel, Ayse B; Snively, Beverly M; Wu, Jer-Yuarn; Schmidt, Reinhold; Fornage, Myriam; Klein, Robert J; Fox, Caroline S; Matsuda, Koichi; Kamatani, Naoyuki; Wild, Philipp S; Stott, David J; Ford, Ian; Slagboom, P Eline; Yang, Jaden; Chu, Audrey Y; Lambert, Amy J; Uitterlinden, André G; Franco, Oscar H; Hofer, Edith; Ginsburg, David; Hu, Bella; Keating, Brendan; Schick, Ursula M; Brody, Jennifer A; Li, Jun Z; Chen, Zhao.

Am J Hum Genet ; 100(1): 51-63, 2017 Jan 05.

Artículo en Inglés | MEDLINE | ID: mdl-28017375

16.

Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.

Westrick, Randal J; Tomberg, Kärt; Siebert, Amy E; Zhu, Guojing; Winn, Mary E; Dobies, Sarah L; Manning, Sara L; Brake, Marisa A; Cleuren, Audrey C; Hobbs, Linzi M; Mishack, Lena M; Johnston, Alexander J; Kotnik, Emilee; Siemieniak, David R; Xu, Jishu; Li, Jun Z; Saunders, Thomas L; Ginsburg, David.

Proc Natl Acad Sci U S A ; 114(36): 9659-9664, 2017 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-28827327

17.

Genome-wide linkage analysis and whole-exome sequencing identifies an ITGA2B mutation in a family with thrombocytopenia.

Khoriaty, Rami; Ozel, Ayse B; Ramdas, Shweta; Ross, Charles; Desch, Karl; Shavit, Jordan A; Everett, Lesley; Siemieniak, David; Li, Jun Z; Ginsburg, David.

Br J Haematol ; 186(4): 574-579, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-31119735

18.

Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13.

Kretz, Colin A; Dai, Manhong; Soylemez, Onuralp; Yee, Andrew; Desch, Karl C; Siemieniak, David; Tomberg, Kärt; Kondrashov, Fyodor A; Meng, Fan; Ginsburg, David.

Proc Natl Acad Sci U S A ; 112(30): 9328-33, 2015 Jul 28.

Artículo en Inglés | MEDLINE | ID: mdl-26170332

19.

Visualization of an N-terminal fragment of von Willebrand factor in complex with factor VIII.

Yee, Andrew; Oleskie, Austin N; Dosey, Anne M; Kretz, Colin A; Gildersleeve, Robert D; Dutta, Somnath; Su, Min; Ginsburg, David; Skiniotis, Georgios.

Blood ; 126(8): 939-42, 2015 Aug 20.

Artículo en Inglés | MEDLINE | ID: mdl-26065653

20.

Murine coagulation factor VIII is synthesized in endothelial cells.

Everett, Lesley A; Cleuren, Audrey C A; Khoriaty, Rami N; Ginsburg, David.

Blood ; 123(24): 3697-705, 2014 Jun 12.

Artículo en Inglés | MEDLINE | ID: mdl-24719406

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