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Wang, Yating; Khan, Abid; Marks, Anna B; Smith, Owen K; Giri, Sumanprava; Lin, Yo-Chuen; Creager, Rachel; MacAlpine, David M; Prasanth, Kannanganattu V; Aladjem, Mirit I; Prasanth, Supriya G.

Nucleic Acids Res ; 45(5): 2490-2502, 2017 03 17.

Artículo en Inglés | MEDLINE | ID: mdl-27924004

15.

Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression.

Kim, Jane C; Nordman, Jared; Xie, Fang; Kashevsky, Helena; Eng, Thomas; Li, Sharon; MacAlpine, David M; Orr-Weaver, Terry L.

Genes Dev ; 25(13): 1384-98, 2011 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-21724831

16.

Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila.

Li, Yulong; Armstrong, Robin L; Duronio, Robert J; MacAlpine, David M.

Nucleic Acids Res ; 44(15): 7204-18, 2016 09 06.

Artículo en Inglés | MEDLINE | ID: mdl-27131378

17.

Conserved nucleosome positioning defines replication origins.

Eaton, Matthew L; Galani, Kyriaki; Kang, Sukhyun; Bell, Stephen P; MacAlpine, David M.

Genes Dev ; 24(8): 748-53, 2010 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-20351051

18.

The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin.

Müller, Philipp; Park, Sookhee; Shor, Erika; Huebert, Dana J; Warren, Christopher L; Ansari, Aseem Z; Weinreich, Michael; Eaton, Matthew L; MacAlpine, David M; Fox, Catherine A.

Genes Dev ; 24(13): 1418-33, 2010 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-20595233

19.

DNA replication and transcription programs respond to the same chromatin cues.

Lubelsky, Yoav; Prinz, Joseph A; DeNapoli, Leyna; Li, Yulong; Belsky, Jason A; MacAlpine, David M.

Genome Res ; 24(7): 1102-14, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24985913

20.

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.

Lujan, Scott A; Clausen, Anders R; Clark, Alan B; MacAlpine, Heather K; MacAlpine, David M; Malc, Ewa P; Mieczkowski, Piotr A; Burkholder, Adam B; Fargo, David C; Gordenin, Dmitry A; Kunkel, Thomas A.

Genome Res ; 24(11): 1751-64, 2014 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-25217194

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SnapShot: Origins of DNA replication.

Stochastic initiation of DNA replication across the human genome.

Disruption of origin chromatin structure by helicase activation in the absence of DNA replication.

Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase.

Linking the dynamics of chromatin occupancy and transcription with predictive models.

Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication.

DNA replication origins-where do we begin?

RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data.

Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly.

Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork.

Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats.

Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila.

Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle.

Temporal association of ORCA/LRWD1 to late-firing origins during G1 dictates heterochromatin replication and organization.