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1.
Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2.
J Pharmacol Exp Ther
; 362(2): 338-346, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28611093
2.
Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660).
Br J Clin Pharmacol
; 83(12): 2813-2820, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28800383
3.
Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor.
Br J Clin Pharmacol
; 81(5): 971-9, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26620151
4.
Circulating soluble receptor for advanced glycation end products (sRAGE) as a biomarker of emphysema and the RAGE axis in the lung.
Am J Respir Crit Care Med
; 192(7): 785-92, 2015 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26132989
5.
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease.
Am J Respir Crit Care Med
; 188(8): 948-57, 2013 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23947473
6.
In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor.
Prostaglandins Other Lipid Mediat
; 104-105: 25-31, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23434473
7.
Different mitogen-activated protein kinase-dependent cytokine responses in cells of the monocyte lineage.
J Pharmacol Exp Ther
; 324(1): 306-12, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17921189
8.
Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers.
Chest
; 151(3): 555-563, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-27884766
9.
Gene expression changes caused by the p38 MAPK inhibitor dilmapimod in COPD patients: analysis of blood and sputum samples from a randomized, placebo-controlled clinical trial.
Pharmacol Res Perspect
; 3(1): e00094, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25692013
10.
A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease.
BMC Syst Biol
; 8 Suppl 2: S8, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25032995
11.
The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study.
Lancet Respir Med
; 1(2): 129-36, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24429093
12.
Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis.
Mol Ther Nucleic Acids
; 2: e65, 2013 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23322014
13.
Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype.
PLoS One
; 7(5): e37483, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22624038
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