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1.
Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation.
PLoS Genet
; 18(10): e1010463, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36288392
2.
Activation of signaling pathways in models of t(6;9)-acute myeloid leukemia.
Ann Hematol
; 101(10): 2179-2193, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-35941390
3.
Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I and BCR-ABL1T315I-E255K.
Ann Hematol
; 100(8): 2023-2029, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34110462
4.
The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia.
PLoS Genet
; 11(4): e1005144, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25919613
5.
Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I.
BMC Cancer
; 12: 411, 2012 Sep 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-22985168
6.
Oncogene-independent resistance in Philadelphia chromosome - positive (Ph+) acute lymphoblastic leukemia (ALL) is mediated by activation of AKT/mTOR pathway.
Neoplasia
; 23(9): 1016-1027, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34403880
7.
The tyrosine kinase inhibitor AMN107 (Nilotinib) exhibits off-target effects in lymphoblastic cell lines.
Leuk Lymphoma
; 48(7): 1379-88, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17613767
8.
Inhibition of phosphotyrosine phosphatase 1B causes resistance in BCR-ABL-positive leukemia cells to the ABL kinase inhibitor STI571.
Clin Cancer Res
; 12(7 Pt 1): 2025-31, 2006 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16609011
9.
Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells.
Cancer Res
; 65(7): 2537-41, 2005 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15805245
10.
The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.
Cancer Res
; 65(14): 6080-8, 2005 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16024608
11.
AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.
Cancer Res
; 62(23): 7050-8, 2002 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12460926
12.
Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571.
Blood
; 102(8): 2985-93, 2003 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12829585
13.
Mobilization and transduction of CD34(+) peripheral blood stem cells in patients with X-linked chronic granulomatous disease.
J Hematother Stem Cell Res
; 11(4): 683-94, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12201957
14.
Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells.
Blood
; 103(9): 3535-43, 2004 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-14739224
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