RESUMEN
We evaluated health-related quality of life in patients with hypothalamic hamartoma, to see how it differs from that of children with more common neurologic disorders. We used the PedsQL 4.0, along with the Child Behavior Checklist, Hague Seizure Severity Scale, and Side Effects Scale, to evaluate presurgical patients with hypothalamic hamartoma and epilepsy (n = 21). The results were compared with those of age-matched cohorts with migraine (n = 19) and Benign Epilepsy with Central Temporal Spikes (n = 11). In comparison with the migraine group, the patients with hypothalamic hamartoma had decreased health-related quality of life across all domains of the PedsQL 4.0. Compared with the benign epilepsy group, the hypothalamic hamartoma cohort has a significantly lower score in School Function. Comorbid psychomotor retardation was predictive of lower quality of life. Research examining the efficacy of recently developed surgical treatments for hypothalamic hamartoma should include health-related quality of life as an outcome measure.
Asunto(s)
Epilepsia/complicaciones , Epilepsia/psicología , Hamartoma/complicaciones , Hamartoma/psicología , Enfermedades Hipotalámicas/complicaciones , Enfermedades Hipotalámicas/psicología , Calidad de Vida , Adolescente , Niño , Trastornos de la Conducta Infantil/diagnóstico , Trastornos de la Conducta Infantil/etiología , Preescolar , Estudios de Cohortes , Femenino , Humanos , Lactante , Masculino , Escalas de Valoración Psiquiátrica , Estudios Retrospectivos , Estadística como AsuntoRESUMEN
A 6-week-old infant was referred for possible Sturge-Weber syndrome. The patient had a segmental hemangioma primarily involving the left eye. Subsequent evaluation suggested the diagnosis of PHACES syndrome, which is discussed. The risks to vision presented by the orbital involvement of the hemangioma should be noted.