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1.
Rheumatology (Oxford) ; 57(10): 1789-1794, 2018 10 01.
Artículo en Inglés | MEDLINE | ID: mdl-29955871

RESUMEN

Objective: To evaluate compliance with hyperlipidaemia screening guidelines for cardiovascular disease prevention in RA compared with the general population. Methods: We conducted a longitudinal study of a population-based RA cohort including all prevalent cases in British Columbia between 1996 and 2006, followed up until 2010, with matched general population controls. Using administrative data, we measured compliance with general population guidelines (testing lipids every 5 years for women ⩾50 and men ⩾40), after excluding individuals with previous diabetes, coronary artery disease or hyperlipidaemia. Compliance was measured as the proportion of 5-year eligibility periods with one or more lipid test. Compliance rates in RA and controls were compared by Chi-square test. Odds ratio (95% CI) of compliance in RA (vs controls) was estimated using generalized estimating equation models, adjusting for age and sex. Mean compliance rate per patient was also calculated and compared using Mann-Whitney U test. Results: Analyses included 5587 RA individuals and 5613 controls, contributing 6993 and 7208 5-year eligibility periods, respectively. Lipids were measured in 56.6 and 59.5% of eligibility periods in RA and controls, respectively [adjusted odds ratio (95% CI): 0.97 (0.90, 1.06)]. Screening improved over time in RA relative to the general population, but remained suboptimal even after 2003, at 65.8%. Mean (s.d.) compliance rate per patient was 56.6 (47.2)% for RA and 59.5 (46.6)% for controls. Family physicians ordered almost all the lipid tests. Conclusion: Compliance with general population guidelines for hyperlipidaemia screening in RA was poor and did not differ from the general population, despite a higher risk of cardiovascular diseases.


Asunto(s)
Artritis Reumatoide/complicaciones , Enfermedades Cardiovasculares/prevención & control , Adhesión a Directriz/estadística & datos numéricos , Hiperlipidemias/prevención & control , Tamizaje Masivo/normas , Cooperación del Paciente/estadística & datos numéricos , Adulto , Anciano , Colombia Británica/epidemiología , Enfermedades Cardiovasculares/etiología , Distribución de Chi-Cuadrado , Estudios de Cohortes , Femenino , Humanos , Hiperlipidemias/etiología , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Oportunidad Relativa , Prevalencia , Estadísticas no Paramétricas
2.
J Rheumatol ; 45(10): 1367-1374, 2018 10.
Artículo en Inglés | MEDLINE | ID: mdl-30008457

RESUMEN

OBJECTIVE: To evaluate compliance with diabetes screening guidelines for cardiovascular disease (CVD) prevention in rheumatoid arthritis (RA) compared to the general population. METHODS: We conducted the first longitudinal study of a population-based RA cohort including all prevalent RA cases in British Columbia between 1996 and 2006 and followed until 2010, with matched general population comparators. Using administrative data, we measured compliance with general population guidelines [i.e., testing plasma glucose (PG) at least once every 3 years after age 45] after excluding individuals with previous diabetes. Followup was divided into 3-year eligibility periods. Compliance was measured as the proportion of periods with ≥ 1 PG test performed. OR (95% CI) of compliance in RA (vs general population) was calculated using generalized estimating equation models, adjusting for age and sex. Mean compliance rate per patient was also calculated and compared using the Mann-Whitney U test. RESULTS: Analysis included 22,624 individuals with RA, contributing 48,724 three-year eligibility periods; and 22,579 people in a general population group, contributing 51,081 three-year eligibility periods. PG was measured in 72.3% (SD 37%) of the eligible time periods in the RA sample and in 70.4% (SD 38%) for the general population (OR 1.05, 95% CI 1.02-1.09, p < 0.0001). RA individuals met recommended screening guidelines in 71.4% of their eligible periods, compared to 70.6% (p < 0.001). Screening improved over time in RA relative to the general population. Family physicians ordered nearly all the PG tests. CONCLUSION: Compliance with general population guidelines for diabetes screening in RA was suboptimal, with little difference relative to the general population, despite a higher risk of CVD and diabetes.


Asunto(s)
Artritis Reumatoide/epidemiología , Enfermedades Cardiovasculares/prevención & control , Diabetes Mellitus/epidemiología , Adhesión a Directriz , Anciano , Anciano de 80 o más Años , Glucemia/análisis , Colombia Británica/epidemiología , Comorbilidad , Femenino , Estudios de Seguimiento , Humanos , Estudios Longitudinales , Masculino , Tamizaje Masivo , Persona de Mediana Edad , Cooperación del Paciente , Prevalencia , Estadísticas no Paramétricas
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