Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

Soluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity.

Kennedy, Paul T; Saulters, Emma L; Duckworth, Andrew D; Lim, Yeong Jer; Woolley, John F; Slupsky, Joseph R; Cragg, Mark S; Ward, Frank J; Dahal, Lekh N.

Mol Ther ; 32(2): 457-468, 2024 Feb 07.

Artículo en Inglés | MEDLINE | ID: mdl-38053333

2.

Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development.

Figueiredo, Carlos R; Kalirai, Helen; Sacco, Joseph J; Azevedo, Ricardo A; Duckworth, Andrew; Slupsky, Joseph R; Coulson, Judy M; Coupland, Sarah E.

J Pathol ; 250(4): 420-439, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-31960425

3.

Poor prognosis is ZAP70'ed into focus in CLL.

Linley, Adam J; Slupsky, Joseph R.

Blood ; 137(26): 3586-3587, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-34196683

4.

UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis.

Abu-Alainin, Wafa; Gana, Thompson; Liloglou, Triantafillos; Olayanju, Adedamola; Barrera, Lawrence N; Ferguson, Robert; Campbell, Fiona; Andrews, Timothy; Goldring, Christopher; Kitteringham, Neil; Park, Brian K; Nedjadi, Taoufik; Schmid, Michael C; Slupsky, Joseph R; Greenhalf, William; Neoptolemos, John P; Costello, Eithne.

J Pathol ; 238(3): 423-33, 2016 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-26497117

5.

Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase Î´ but not SYK or BTK in chronic lymphocytic leukemia cells.

Till, Kathleen J; Pettitt, Andrew R; Slupsky, Joseph R.

J Immunol ; 194(5): 2439-46, 2015 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-25632006

6.

Ibrutinib is safer than we think.

Slupsky, Joseph R.

Blood ; 133(19): 2006-2007, 2019 05 09.

Artículo en Inglés | MEDLINE | ID: mdl-31072962

7.

Variable induction of PRDM1 and differentiation in chronic lymphocytic leukemia is associated with anergy.

Duckworth, Andrew; Glenn, Mark; Slupsky, Joseph R; Packham, Graham; Kalakonda, Nagesh.

Blood ; 123(21): 3277-85, 2014 May 22.

Artículo en Inglés | MEDLINE | ID: mdl-24637363

8.

Highly Multiplexed and Simultaneous Characterization of Protein and RNA in Single Cells by Flow or Mass Cytometry Platforms Using Proximity Ligation Assay for RNA.

Duckworth, Andrew D; Slupsky, Joseph R; Kalakonda, Nagesh.

Methods Mol Biol ; 2752: 143-165, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38194033

9.

c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells.

Allen, John C; Talab, Fatima; Zuzel, Mirko; Lin, Ke; Slupsky, Joseph R.

Blood ; 117(8): 2414-22, 2011 Feb 24.

Artículo en Inglés | MEDLINE | ID: mdl-21220745

10.

Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression.

Lucas, Claire M; Harris, Robert J; Giannoudis, Athina; Copland, Mhairi; Slupsky, Joseph R; Clark, Richard E.

Blood ; 117(24): 6660-8, 2011 Jun 16.

Artículo en Inglés | MEDLINE | ID: mdl-21490338

11.

Roles of PI3KÎ³ and PI3KÎ´ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3KÎ³/Î´ inhibitor duvelisib.

Till, Kathleen J; Abdullah, Mariah; Alnassfan, Tahera; Janet, Gallardo Zapata; Marks, Thomas; Coma, Silvia; Weaver, David T; Pachter, Jonathan A; Pettitt, Andrew R; Slupsky, Joseph R.

Sci Rep ; 13(1): 3793, 2023 03 07.

Artículo en Inglés | MEDLINE | ID: mdl-36882482

12.

Enhancing BCR signals at the cell membrane.

Slupsky, Joseph R.

Blood ; 125(4): 586-7, 2015 Jan 22.

Artículo en Inglés | MEDLINE | ID: mdl-25614635

13.

Vascular endothelial growth factor stimulates protein kinase CbetaII expression in chronic lymphocytic leukemia cells.

Abrams, Simon T; Brown, Benjamin R B; Zuzel, Mirko; Slupsky, Joseph R.

Blood ; 115(22): 4447-54, 2010 Jun 03.

Artículo en Inglés | MEDLINE | ID: mdl-20164467

14.

PKCß Facilitates Leukemogenesis in Chronic Lymphocytic Leukaemia by Promoting Constitutive BCR-Mediated Signalling.

Hay, Jodie; Tarafdar, Anuradha; Holroyd, Ailsa K; Moka, Hothri A; Dunn, Karen M; Alshayeb, Alzahra; Lloyd, Bryony H; Cassels, Jennifer; Malik, Natasha; Khan, Ashfia F; Sou, IengFong; Lees, Jamie; Almuhanna, Hassan N B; Kalakonda, Nagesh; Slupsky, Joseph R; Michie, Alison M.

Cancers (Basel) ; 14(23)2022 Dec 06.

Artículo en Inglés | MEDLINE | ID: mdl-36497487

15.

Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells.

Linley, Adam J; Karydis, Laura I; Mondru, Anil K; D'Avola, Annalisa; Al Shmrany, Humood; Cicconi, Silvia; Griffin, Rebecca; Forconi, Francesco; Pettitt, Andrew R; Kalakonda, Nagesh; Rawstron, Andrew C; Hillmen, Peter; Steele, Andrew J; MacEwan, David J; Packham, Graham; Prior, Ian A; Slupsky, Joseph R.

Clin Cancer Res ; 27(20): 5647-5659, 2021 10 15.

Artículo en Inglés | MEDLINE | ID: mdl-34380642

16.

A novel transgenic mouse strain expressing PKCßII demonstrates expansion of B1 and marginal zone B cell populations.

Azar, Ali A; Michie, Alison M; Tarafdar, Anuradha; Malik, Natasha; Menon, Geetha K; Till, Kathleen J; Vlatkovic, Nikolina; Slupsky, Joseph R.

Sci Rep ; 10(1): 13156, 2020 08 04.

Artículo en Inglés | MEDLINE | ID: mdl-32753714

17.

Multiplexed profiling of RNA and protein expression signatures in individual cells using flow or mass cytometry.

Duckworth, Andrew D; Gherardini, Pier Federico; Sykorova, Martina; Yasin, Faten; Nolan, Garry P; Slupsky, Joseph R; Kalakonda, Nagesh.

Nat Protoc ; 14(3): 901-920, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30728478

18.

c-Abl expression in chronic lymphocytic leukemia cells: clinical and therapeutic implications.

Lin, Ke; Glenn, Mark A; Harris, Robert J; Duckworth, Andrew D; Dennett, Sally; Cawley, John C; Zuzel, Mirko; Slupsky, Joseph R.

Cancer Res ; 66(15): 7801-9, 2006 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-16885384

19.

New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome.

Wilson, Leah J; Linley, Adam; Hammond, Dean E; Hood, Fiona E; Coulson, Judy M; MacEwan, David J; Ross, Sarah J; Slupsky, Joseph R; Smith, Paul D; Eyers, Patrick A; Prior, Ian A.

Cancer Res ; 78(1): 15-29, 2018 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-29254998

20.

B-cell receptor translocation to lipid rafts and associated signaling differ between prognostically important subgroups of chronic lymphocytic leukemia.

Allsup, David J; Kamiguti, Aura S; Lin, Ke; Sherrington, Paul D; Matrai, Zoltan; Slupsky, Joseph R; Cawley, John C; Zuzel, Mirko.

Cancer Res ; 65(16): 7328-37, 2005 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-16103084

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