Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

Cortical miR-709 links glutamatergic signaling to NREM sleep EEG slow waves in an activity-dependent manner.

Kompotis, Konstantinos; Mang, Géraldine M; Hubbard, Jeffrey; Jimenez, Sonia; Emmenegger, Yann; Polysopoulos, Christos; Hor, Charlotte N; Wigger, Leonore; Hébert, Sébastien S; Mongrain, Valérie; Franken, Paul.

Proc Natl Acad Sci U S A ; 121(3): e2220532121, 2024 Jan 16.

Artículo en Inglés | MEDLINE | ID: mdl-38207077

2.

Assessment of the Cardiac Noncoding Transcriptome by Single-Cell RNA Sequencing Identifies FIXER, a Conserved Profibrogenic Long Noncoding RNA.

Aghagolzadeh, Parisa; Plaisance, Isabelle; Bernasconi, Riccardo; Treibel, Thomas A; Pulido Quetglas, Carlos; Wyss, Tania; Wigger, Leonore; Nemir, Mohamed; Sarre, Alexandre; Chouvardas, Panagiotis; Johnson, Rory; González, Arantxa; Pedrazzini, Thierry.

Circulation ; 148(9): 778-797, 2023 08 29.

Artículo en Inglés | MEDLINE | ID: mdl-37427428

3.

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.

Solimena, Michele; Schulte, Anke M; Marselli, Lorella; Ehehalt, Florian; Richter, Daniela; Kleeberg, Manuela; Mziaut, Hassan; Knoch, Klaus-Peter; Parnis, Julia; Bugliani, Marco; Siddiq, Afshan; Jörns, Anne; Burdet, Frédéric; Liechti, Robin; Suleiman, Mara; Margerie, Daniel; Syed, Farooq; Distler, Marius; Grützmann, Robert; Petretto, Enrico; Moreno-Moral, Aida; Wegbrod, Carolin; Sönmez, Anke; Pfriem, Katja; Friedrich, Anne; Meinel, Jörn; Wollheim, Claes B; Baretton, Gustavo B; Scharfmann, Raphael; Nogoceke, Everson; Bonifacio, Ezio; Sturm, Dorothée; Meyer-Puttlitz, Birgit; Boggi, Ugo; Saeger, Hans-Detlev; Filipponi, Franco; Lesche, Mathias; Meda, Paolo; Dahl, Andreas; Wigger, Leonore; Xenarios, Ioannis; Falchi, Mario; Thorens, Bernard; Weitz, Jürgen; Bokvist, Krister; Lenzen, Sigurd; Rutter, Guy A; Froguel, Philippe; von Bülow, Manon; Ibberson, Mark.

Diabetologia ; 61(3): 641-657, 2018 03.

Artículo en Inglés | MEDLINE | ID: mdl-29185012

4.

Malaria haplotype frequency estimation.

Wigger, Leonore; Vogt, Julia E; Roth, Volker.

Stat Med ; 32(21): 3737-51, 2013 Sep 20.

Artículo en Inglés | MEDLINE | ID: mdl-23609602

5.

Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock.

Bignon, Yohan; Wigger, Leonore; Ansermet, Camille; Weger, Benjamin D; Lagarrigue, Sylviane; Centeno, Gabriel; Durussel, Fanny; Götz, Lou; Ibberson, Mark; Pradervand, Sylvain; Quadroni, Manfredo; Weger, Meltem; Amati, Francesca; Gachon, Frédéric; Firsov, Dmitri.

J Clin Invest ; 133(8)2023 04 17.

Artículo en Inglés | MEDLINE | ID: mdl-36862511

6.

A combination of plasma membrane sterol biosynthesis and autophagy is required for shade-induced hypocotyl elongation.

Ince, Yetkin Çaka; Krahmer, Johanna; Fiorucci, Anne-Sophie; Trevisan, Martine; Galvão, Vinicius Costa; Wigger, Leonore; Pradervand, Sylvain; Fouillen, Laetitia; Van Delft, Pierre; Genva, Manon; Mongrand, Sebastien; Gallart-Ayala, Hector; Ivanisevic, Julijana; Fankhauser, Christian.

Nat Commun ; 13(1): 5659, 2022 10 10.

Artículo en Inglés | MEDLINE | ID: mdl-36216814

7.

Plasma triacylglycerols are biomarkers of ß-cell function in mice and humans.

Sánchez-Archidona, Ana Rodríguez; Cruciani-Guglielmacci, Céline; Roujeau, Clara; Wigger, Leonore; Lallement, Justine; Denom, Jessica; Barovic, Marko; Kassis, Nadim; Mehl, Florence; Weitz, Jurgen; Distler, Marius; Klose, Christian; Simons, Kai; Ibberson, Mark; Solimena, Michele; Magnan, Christophe; Thorens, Bernard.

Mol Metab ; 54: 101355, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34634522

8.

Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes.

Wigger, Leonore; Barovic, Marko; Brunner, Andreas-David; Marzetta, Flavia; Schöniger, Eyke; Mehl, Florence; Kipke, Nicole; Friedland, Daniela; Burdet, Frederic; Kessler, Camille; Lesche, Mathias; Thorens, Bernard; Bonifacio, Ezio; Legido-Quigley, Cristina; Barbier Saint Hilaire, Pierre; Delerive, Philippe; Dahl, Andreas; Klose, Christian; Gerl, Mathias J; Simons, Kai; Aust, Daniela; Weitz, Jürgen; Distler, Marius; Schulte, Anke M; Mann, Matthias; Ibberson, Mark; Solimena, Michele.

Nat Metab ; 3(7): 1017-1031, 2021 07.

Artículo en Inglés | MEDLINE | ID: mdl-34183850

9.

Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients.

Fontana, Pierre; Ibberson, Mark; Stevenson, Brian; Wigger, Leonore; Daali, Youssef; Niknejad, Anne; Mach, François; Docquier, Mylène; Xenarios, Ioannis; Cuisset, Thomas; Alessi, Marie-Christine; Reny, Jean-Luc.

J Thromb Haemost ; 18(6): 1425-1434, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32077582

10.

Sensory neuron lineage mapping and manipulation in the Drosophila olfactory system.

Chai, Phing Chian; Cruchet, Steeve; Wigger, Leonore; Benton, Richard.

Nat Commun ; 10(1): 643, 2019 02 07.

Artículo en Inglés | MEDLINE | ID: mdl-30733440

11.

Use of preclinical models to identify markers of type 2 diabetes susceptibility and novel regulators of insulin secretion - A step towards precision medicine.

Thorens, Bernard; Rodriguez, Ana; Cruciani-Guglielmacci, Céline; Wigger, Leonore; Ibberson, Mark; Magnan, Christophe.

Mol Metab ; 27S: S147-S154, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-31500826

12.

System analysis of cross-talk between nuclear receptors reveals an opposite regulation of the cell cycle by LXR and FXR in human HepaRG liver cells.

Wigger, Leonore; Casals-Casas, Cristina; Baruchet, Michaël; Trang, Khanh B; Pradervand, Sylvain; Naldi, Aurélien; Desvergne, Béatrice.

PLoS One ; 14(8): e0220894, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31437187

13.

Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.

Wigger, Leonore; Cruciani-Guglielmacci, Céline; Nicolas, Anthony; Denom, Jessica; Fernandez, Neïké; Fumeron, Frédéric; Marques-Vidal, Pedro; Ktorza, Alain; Kramer, Werner; Schulte, Anke; Le Stunff, Hervé; Liechti, Robin; Xenarios, Ioannis; Vollenweider, Peter; Waeber, Gérard; Uphues, Ingo; Roussel, Ronan; Magnan, Christophe; Ibberson, Mark; Thorens, Bernard.

Cell Rep ; 18(9): 2269-2279, 2017 02 28.

Artículo en Inglés | MEDLINE | ID: mdl-28249170

14.

Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion.

Cruciani-Guglielmacci, Céline; Bellini, Lara; Denom, Jessica; Oshima, Masaya; Fernandez, Neïké; Normandie-Levi, Priscilla; Berney, Xavier P; Kassis, Nadim; Rouch, Claude; Dairou, Julien; Gorman, Tracy; Smith, David M; Marley, Anna; Liechti, Robin; Kuznetsov, Dmitry; Wigger, Leonore; Burdet, Frédéric; Lefèvre, Anne-Laure; Wehrle, Isabelle; Uphues, Ingo; Hildebrandt, Tobias; Rust, Werner; Bernard, Catherine; Ktorza, Alain; Rutter, Guy A; Scharfmann, Raphael; Xenarios, Ioannis; Le Stunff, Hervé; Thorens, Bernard; Magnan, Christophe; Ibberson, Mark.

Mol Metab ; 6(4): 340-351, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-28377873

15.

A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice.

Mang, Géraldine M; Pradervand, Sylvain; Du, Ngoc-Hien; Arpat, Alaaddin Bulak; Preitner, Frédéric; Wigger, Leonore; Gatfield, David; Franken, Paul.

PLoS One ; 10(1): e0116760, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-25629159

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