Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

Stem cells, quiescence and rectal carcinoma: an unexplored relationship and potential therapeutic target.

Buczacki, S; Davies, R J; Winton, D J.

Br J Cancer ; 105(9): 1253-9, 2011 Oct 25.

Artículo en Inglés | MEDLINE | ID: mdl-21934687

2.

Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice.

Luo, F; Brooks, D G; Ye, H; Hamoudi, R; Poulogiannis, G; Patek, C E; Winton, D J; Arends, M J.

Oncogene ; 26(30): 4415-27, 2007 Jun 28.

Artículo en Inglés | MEDLINE | ID: mdl-17297472

3.

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.

Huels, D J; Bruens, L; Hodder, M C; Cammareri, P; Campbell, A D; Ridgway, R A; Gay, D M; Solar-Abboud, M; Faller, W J; Nixon, C; Zeiger, L B; McLaughlin, M E; Morrissey, E; Winton, D J; Snippert, H J; van Rheenen, J; Sansom, O J.

Nat Commun ; 9(1): 1132, 2018 03 19.

Artículo en Inglés | MEDLINE | ID: mdl-29556067

4.

Mutagenesis of mouse intestine in vivo using the Dlb-1 specific locus test: studies with 1,2-dimethylhydrazine, dimethylnitrosamine, and the dietary mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.

Winton, D J; Gooderham, N J; Boobis, A R; Davies, D S; Ponder, B A.

Cancer Res ; 50(24): 7992-6, 1990 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-2253241

5.

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is a potent mutagen in the mouse small intestine.

Brooks, R A; Gooderham, N J; Zhao, K; Edwards, R J; Howard, L A; Boobis, A R; Winton, D J.

Cancer Res ; 54(7): 1665-71, 1994 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-8137279

6.

p53, mutation frequency and apoptosis in the murine small intestine.

Clarke, A R; Howard, L A; Harrison, D J; Winton, D J.

Oncogene ; 14(17): 2015-8, 1997 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-9160880

7.

Msh-2 suppresses in vivo mutation in a gene dose and lesion dependent manner.

Sansom, O J; Toft, N J; Winton, D J; Clarke, A R.

Oncogene ; 20(27): 3580-4, 2001 Jun 14.

Artículo en Inglés | MEDLINE | ID: mdl-11429706

8.

C-cell and thyroid epithelial tumours and altered follicular development in transgenic mice expressing the long isoform of MEN 2A RET.

Reynolds, L; Jones, K; Winton, D J; Cranston, A; Houghton, C; Howard, L; Ponder, B A; Smith, D P.

Oncogene ; 20(30): 3986-94, 2001 Jul 05.

Artículo en Inglés | MEDLINE | ID: mdl-11494127

9.

Stem-cell organization in mouse small intestine.

Winton, D J; Ponder, B A.

Proc Biol Sci ; 241(1300): 13-8, 1990 Jul 23.

Artículo en Inglés | MEDLINE | ID: mdl-1978330

10.

Gene-mutation assays in lambda lacZ transgenic mice: comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium.

van Delft, J H; Bergmans, A; van Dam, F J; Tates, A D; Howard, L; Winton, D J; Baan, R A.

Mutat Res ; 415(1-2): 85-96, 1998 Jul 08.

Artículo en Inglés | MEDLINE | ID: mdl-9711265

11.

ß-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.

Ahmad, I; Morton, J P; Singh, L B; Radulescu, S M; Ridgway, R A; Patel, S; Woodgett, J; Winton, D J; Taketo, M M; Wu, X-R; Leung, H Y; Sansom, O J.

Oncogene ; 30(2): 178-89, 2011 Jan 13.

Artículo en Inglés | MEDLINE | ID: mdl-20818428

12.

Quantitative electron microscopy of carcinogen-induced alterations in hepatocyte rough endoplasmic reticulum. II. Modulation of the effects of 3'MeDAB by adrenalectomy and adrenal corticosteroids.

Winton, D J; Flaks, B.

Br J Exp Pathol ; 70(3): 369-84, 1989 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-2504269

13.

Fine structural alterations induced in the rat hepatocyte by adrenalectomy: influence of deoxycorticosterone acetate or fasting.

Winton, D J; Flaks, B.

Br J Exp Pathol ; 68(4): 475-84, 1987 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-3651322

14.

Effect of fasting on aggregation of hepatocyte rough endoplasmic reticulum in adrenalectomized and 3'MeDAB-treated rats: quantitative electron microscope study.

Winton, D J; Flaks, B.

Br J Exp Pathol ; 69(6): 877-89, 1988 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-3146340

15.

Determination of spatial patterns of DNA damage and repair in intestinal crypts by multi-cell gel electrophoresis.

Brooks, R A; Winton, D J.

J Cell Sci ; 109 ( Pt 8): 2061-8, 1996 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-8856502

16.

Analysis of DNA damage and repair accompanying differentiation in the intestinal crypt.

Winton, D J; Brooks, R A.

Philos Trans R Soc Lond B Biol Sci ; 353(1370): 895-902, 1998 Jun 29.

Artículo en Inglés | MEDLINE | ID: mdl-9684286

17.

Possible non-functional crypts in small intestine defined using mouse aggregation chimaeras.

Winton, D J; Howard, L; Ponder, B A.

Epithelial Cell Biol ; 1(2): 59-64, 1992 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-1307940

18.

A clonal marker induced by mutation in mouse intestinal epithelium.

Winton, D J; Blount, M A; Ponder, B A.

Nature ; 333(6172): 463-6, 1988 Jun 02.

Artículo en Inglés | MEDLINE | ID: mdl-3163778

19.

Quantitative electron microscopy of carcinogen-induced alterations in hepatocyte rough endoplasmic reticulum. I. Chronic effect of 3'MeDAB and short-term effects of azo dyes of different carcinogenic potentials.

Winton, D J; Flaks, B; Flaks, A.

Carcinogenesis ; 9(6): 987-99, 1988 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-3131035

20.

Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine.

Schmidt, G H; Winton, D J; Ponder, B A.

Development ; 103(4): 785-90, 1988 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-3248525

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Stem cells, quiescence and rectal carcinoma: an unexplored relationship and potential therapeutic target.

Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice.

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.

Mutagenesis of mouse intestine in vivo using the Dlb-1 specific locus test: studies with 1,2-dimethylhydrazine, dimethylnitrosamine, and the dietary mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is a potent mutagen in the mouse small intestine.

p53, mutation frequency and apoptosis in the murine small intestine.

Msh-2 suppresses in vivo mutation in a gene dose and lesion dependent manner.

C-cell and thyroid epithelial tumours and altered follicular development in transgenic mice expressing the long isoform of MEN 2A RET.

Stem-cell organization in mouse small intestine.

Gene-mutation assays in lambda lacZ transgenic mice: comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium.

ß-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.

Quantitative electron microscopy of carcinogen-induced alterations in hepatocyte rough endoplasmic reticulum. II. Modulation of the effects of 3'MeDAB by adrenalectomy and adrenal corticosteroids.

Fine structural alterations induced in the rat hepatocyte by adrenalectomy: influence of deoxycorticosterone acetate or fasting.

Effect of fasting on aggregation of hepatocyte rough endoplasmic reticulum in adrenalectomized and 3'MeDAB-treated rats: quantitative electron microscope study.

Determination of spatial patterns of DNA damage and repair in intestinal crypts by multi-cell gel electrophoresis.

Analysis of DNA damage and repair accompanying differentiation in the intestinal crypt.

Possible non-functional crypts in small intestine defined using mouse aggregation chimaeras.

A clonal marker induced by mutation in mouse intestinal epithelium.

Quantitative electron microscopy of carcinogen-induced alterations in hepatocyte rough endoplasmic reticulum. I. Chronic effect of 3'MeDAB and short-term effects of azo dyes of different carcinogenic potentials.

Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine.