Detalles de la búsqueda
1.
Conversion therapy for advanced hepatocellular carcinoma in the era of precision medicine: Current status, challenges and opportunities.
Cancer Sci
; 2024 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38695305
2.
7ß-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues.
Bioorg Med Chem
; 26(14): 4254-4263, 2018 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30054192
3.
Discovery, stereospecific characterization and peripheral modification of 1-(pyrrolidin-1-ylmethyl)-2-[(6-chloro-3-oxo-indan)-formyl]-1,2,3,4-tetrahydroisoquinolines as novel selective κ opioid receptor agonists.
Org Biomol Chem
; 13(20): 5656-73, 2015 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-25895552
4.
Design, synthesis and biological evaluation of N-phenylalkyl-substituted tramadol derivatives as novel µ opioid receptor ligands.
Acta Pharmacol Sin
; 36(7): 887-94, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-26051109
5.
Novel κ-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation.
Acta Pharmacol Sin
; 36(5): 565-71, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25816912
6.
Spectroscopic Study on the Interaction between Naphthalimide-Polyamine Conjugates and Bovine Serum Albumin (BSA).
Molecules
; 20(9): 16491-523, 2015 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26378511
7.
Unscheduled screening tests cannot be termed as surveillance.
Hepatology
; 66(3): 1001-1002, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28543365
8.
Serine 363 of the {delta}-opioid receptor is crucial for adopting distinct pathways to activate ERK1/2 in response to stimulation with different ligands.
J Cell Sci
; 123(Pt 24): 4259-70, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21098639
9.
[An oligopeptide improves solubility of paclitaxel by non-covalent interaction].
Yao Xue Xue Bao
; 47(7): 947-52, 2012 Jul.
Artículo
en Zh
| MEDLINE | ID: mdl-22993863
10.
Highly selective and potent mu opioid ligands by unexpected substituent on morphine skeleton.
Bioorg Med Chem Lett
; 20(1): 418-21, 2010 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19932964
11.
Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence.
Acta Pharmacol Sin
; 31(4): 393-8, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20228826
12.
Effects of ATPM-ET, a novel κ agonist with partial µ activity, on physical dependence and behavior sensitization in mice.
Acta Pharmacol Sin
; 31(12): 1547-52, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21102484
13.
Adenosine A(1) receptor agonist N(6)-cyclohexyl-adenosine induced phosphorylation of delta opioid receptor and desensitization of its signaling.
Acta Pharmacol Sin
; 31(7): 784-90, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-20562901
14.
Downregulation of p53 by Insufficient CTCF in CD4+ T Cells Is an Important Factor Inducing Acute Graft-Versus-Host Disease.
Front Immunol
; 11: 568637, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33133081
15.
Role of Src in ligand-specific regulation of delta-opioid receptor desensitization and internalization.
J Neurochem
; 108(1): 102-14, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19014372
16.
Pharmacological characterization of ATPM [(-)-3-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a novel mixed kappa-agonist and mu-agonist/-antagonist that attenuates morphine antinociceptive tolerance and heroin self-administration behavior.
J Pharmacol Exp Ther
; 329(1): 306-13, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19136637
17.
LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.
Eur J Pharmacol
; 584(2-3): 306-11, 2008 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-18353307
18.
Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a κ Partial Agonist and µ Partial Agonist.
Sci Rep
; 8(1): 14087, 2018 09 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30237513
19.
Heteromers of µ opioid and dopamine D1 receptors modulate opioid-induced locomotor sensitization in a dopamine-independent manner.
Br J Pharmacol
; 174(17): 2842-2861, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28608532
20.
The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent κ-Opioid Agonistic Activities.
ACS Chem Neurosci
; 8(4): 766-776, 2017 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-28033462