[Multifocal tuberculosis associated with cerebral toxoplasmosis in an African immigrant immunocompromised patient due to HIV-infection at the Hospital Centre in Soissons, France]. / Tuberculose multifocale associée à une toxoplasmose cérébrale sur terrain immunodéprimé à VIH chez un patient immigré africain au Centre Hospitalier de Soissons, France.

In the industrialized countries and, in particular, in France, given the means of prevention, early screening and treatment of HIV infection, there is almost no evidence of opportunistic infections among immigrants and in some disadvantaged socio-professional groups. We here report the case of a 42-year old African immigrant HIV1 positive man with impaired general condition hospitalized for infectious syndrome. He had received antiretroviral therapy for 2 years and stopped it four months before admission. He had had pulmonary tuberculosis treated and declared cured in February 2017. Clinical examination showed slow ideation, a temperature of 39.6°C and weight loss. The patient had nadir CD4 cell counts 12/mm3 and HIV viral load log value 5.80. Thoracoabdominal CT scan and brain MRI showed intra-abdominal and thoracic lesions as well as brain lesions before diagnostic confirmation of tuberculosis and toxoplasmosis. The patient underwent triple antiretroviral therapy on day 15 of antituberculosis treatment. Then he underwent toxoplasmosis treatment with favorable outcome.

Global health in the making: health demonstration areas in Europe, 1950s and 1960s / Construcción de la salud global: zonas de demostración sanitaria en Europa, décadas de 1950 y 1960

Abstract Global health is a multifaceted concept that entails the standardization of procedures in healthcare domains in accordance with a doctrine agreed upon by experts. This essay focus on the creation of health demonstration areas by the World Health Organisation (WHO) to establish core nodes for integrated state-of-the-art health services. It explores the origins, theoretical basis and aims of this technique and reviews several European experiences during the first 20 years of the WHO. Particular attention is paid to the historical importance of technical cooperative activities carried out by the WHO in regard to the implementation of health services, a long-term strategic move that contributed to the thematic upsurge of primary health care in the late 1970s.

Resumen Salud global es un concepto complejo que implica la normalización de los procedimientos de actuación sanitaria siguiendo una doctrina acordada por expertos. Este trabajo se ocupa del establecimiento de zonas de demostración sanitaria por la Organización Mundial de la Salud (OMS) a modo de núcleos de modernos servicios sanitarios integrados. Revisa el origen, las bases téoricas y los objetivos de esta técnica y examina diversas experiencias europeas durante los primeros veinte años de la OMS. Pone de manifiesto la importancia histórica de las actividades de cooperación técnica de la OMS en la puesta en marcha de servicios sanitarios, una estrategia de largo plazo que ayuda a entender la aparición de la atención primaria de salud a finales de la década de 1970.