RESUMEN
Granulomatous periorificial dermatitis is a clinical variant of periorificial dermatitis. We present the case of an 18-year-old girl with several reddish papular lesions in the perioral, perinasal, and periorbital regions unresponsive to conventional therapy. After 6 months of therapy with low-dose oral isotretinoin, the lesions fully remitted.
Asunto(s)
Dermatitis Perioral/tratamiento farmacológico , Fármacos Dermatológicos/uso terapéutico , Granuloma/tratamiento farmacológico , Isotretinoína/uso terapéutico , Administración Oral , Adolescente , Dermatitis Perioral/patología , Relación Dosis-Respuesta a Droga , Femenino , Granuloma/patología , HumanosRESUMEN
Childhood granulomatous periorificial dermatitis (CGPD) is a self-limiting skin condition characterized by papular eruptions around the mouth, nose and eyes of preadolescent children. We report two cases of intractable CGPD in which patients receiving growth hormone (GH) therapy showed persistent symptoms despite multiple treatment modalities. This association may suggest the role of GH in the pathogenesis of CGPD.