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2.
J Clin Apher ; 34(4): 434-444, 2019 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-30829434

RESUMEN

There has been an increase in the use of therapeutic plasma exchange (TPE) in immune-mediated neurological disorders in recent years. However, accessibility and availability of TPE remains low and costly, especially for a country with limited healthcare funding like Malaysia. With expanding clinical indications in neurological disorders, and increasingly expensive conventional immunomodulatory treatment such as intravenous immunoglobulin and monoclonal antibodies, TPE remains an effective part of first or second-line treatment. In this article, we detailed the historical aspects of the use of TPE in neurological disorders in Malaysia over the last four decades and discussed the challenges behind the establishment of the first in-house neurology-driven TPE service in the country. Local TPE database from a national neurology centre in Kuala Lumpur over the past 20 years was analyzed. We observed a remarkable three folds increase in the use of TPE at our center over the past 10 years (total 131 TPE treatments) compared to a decade prior, with expanding clinical indications predominantly for central nervous system demyelinating disorders. Besides using membrane filtration method, centrifugal technique was adopted, providing new opportunities for other clinical beneficiaries such as a neurologist driven "in-house TPE unit". However, there were real world challenges, especially having to provide services with limited funding, human resources, and space. In addition, much has to be done to improve accessibility, availability, and sustainability of TPE services at our center and nationwide. Nevertheless, even with limited resources and support, it is possible with concerted efforts to work within the confines of these limitations to establish a safe, successful, and sustainable TPE service.


Asunto(s)
Tecnología Biomédica/métodos , Hospitales Públicos/métodos , Neurología/métodos , Intercambio Plasmático/métodos , Anticuerpos Monoclonales/uso terapéutico , Enfermedades Autoinmunes del Sistema Nervioso/terapia , Tecnología Biomédica/tendencias , Enfermedades del Sistema Nervioso Central/terapia , Hospitales Públicos/economía , Humanos , Inmunoglobulinas Intravenosas/uso terapéutico , Intercambio Plasmático/economía , Intercambio Plasmático/tendencias
3.
Anesth Analg ; 126(6): 2056-2064, 2018 06.
Artículo en Inglés | MEDLINE | ID: mdl-29293184

RESUMEN

BACKGROUND: Cesarean delivery is the most common surgical procedure in low- and middle-income countries, so provision of anesthesia services can be measured in relation to it. This study aimed to assess the type of anesthesia used for cesarean delivery, the level of training of anesthesia providers, and to document the availability of essential anesthetic drugs and equipment in provincial, district, and mission hospitals in Zimbabwe. METHODS: In this cross-sectional survey of 8 provincial, 21 district, and 13 mission hospitals, anesthetic providers were interviewed on site using a structured questionnaire adapted from standard instruments developed by the World Federation of Societies of Anaesthesiologists and the World Health Organization. RESULTS: The anesthetic workforce for the hospitals in this survey constituted 22% who were medical officers and 77% nurse anesthetists (NAs); 55% of NAs were recognized independent anesthetic providers, while 26% were qualified as assistants to anesthetic providers and 19% had no formal training in anesthesia. The only specialist physician anesthetist was part time in a provincial hospital. Spinal anesthesia was the most commonly used method for cesarean delivery (81%) in the 3 months before interview, with 19% general anesthesia of which 4% was ketamine without airway intubation. The mean institutional cesarean delivery rate was 13.6% of live births, although 5 district hospitals were <5%. The estimated institutional maternal mortality ratio was 573 (provincial), 251 (district), and 211 (mission hospitals) per 100,000 live births. Basic monitoring equipment (oximeters, electrocardiograms, sphygmomanometers) was reported available in theatres. Several unsafe practices continue: general anesthesia without a secure airway, shortage of essential drugs for spinal anesthesia, inconsistent use of recovery area or use of table tilt or wedge, and insufficient blood supplies. Postoperative analgesia management was reported inadequate. CONCLUSIONS: This study identified areas where anesthetic provision and care could be improved. Provincial hospitals, where district/mission hospitals refer difficult cases, did not have the higher level anesthesia expertise required to manage these cases. More intensive mentorship and supervision from senior clinicians is essential to address the shortcomings identified in this survey, such as the implementation of evidence-based safe practices, supply chain failures, high maternal morbidity, and mortality. Training of medical officers and NAs should be strengthened in leadership, team work, and management of complications.


Asunto(s)
Anestesia/métodos , Cesárea/métodos , Países en Desarrollo , Personal de Salud , Hospitales Privados , Hospitales Públicos/métodos , Anestesia/economía , Anestesia/tendencias , Cesárea/economía , Cesárea/tendencias , Estudios Transversales , Países en Desarrollo/economía , Femenino , Personal de Salud/economía , Personal de Salud/tendencias , Hospitales Privados/economía , Hospitales Privados/tendencias , Hospitales Públicos/economía , Hospitales Públicos/tendencias , Humanos , Embarazo , Distribución Aleatoria , Zimbabwe/epidemiología
4.
Holist Nurs Pract ; 32(4): 182-188, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29894373

RESUMEN

The Supportive Care Nursing Clinical Protocol (SCNCP) was developed to guide holistic nursing care for seriously ill hospitalized patients. The SCNCP uses national guidelines and evidence-based interventions as its foundation. Seriously ill patients may require palliative care, which is synonymous with supportive care. Acute care nurses may not be proficient in providing holistic supportive care for patients with life-limiting illness. At a 670-bed public acute care hospital, palliative care consultation requires a physician order and palliation may arrive late in an illness. Independent nursing interventions can contribute to the alleviation of suffering. Evidence-based interventions used in the SCNCP include using computer applications for breathing exercise (relaxation and mindfulness), topical applications for alleviating thirst, and hand-held fans for dyspnea. The SCNCP is projected for implementation (Spring 2017). The SCNCP will be evaluated for effectiveness after 6 months of implementation. Key indicators for successful implementation include increased nursing knowledge of supportive care and the frequency of protocol implementation as evidenced in the electronic health record. Eventually, the SCNCP will be implemented as the standard for supportive care of the seriously ill for all hospitals in the health system network.


Asunto(s)
Protocolos Clínicos , Enfermería Holística/métodos , Hospitales Públicos/métodos , Hospitales Públicos/organización & administración , Humanos , Atención Plena , Cuidados Paliativos/métodos
5.
BMC Pregnancy Childbirth ; 17(1): 149, 2017 May 22.
Artículo en Inglés | MEDLINE | ID: mdl-28532393

RESUMEN

BACKGROUND: Reducing maternal mortality remains a major challenge for health care systems worldwide. The factors related to maternal mortality were extensively researched, and maternal death clusters around labour, delivery and the immediate postpartum period. Studies on the quality of maternal care in academic medical centre settings in low income countries are uncommon. METHODS: A retrospective cohort study of maternal deaths was conducted in an academic public tertiary hospital in Yogyakarta, and maternal near misses were used as controls. Data were obtained from medical records from February 1, 2011 to September 30, 2012. Three groups of variables were measured: (1) timeliness of care, (2) adherence to a standard of process indicators, and (3) associated extraneous variables. Variables were analysed using logistic regression to explore their effects on maternal mortality. RESULTS: The mean of triage response time and obstetric resident response time were longer in maternal deaths (8 ± 3.59 and 36.17 ± 23.48 min respectively) compared to near misses (1.29 ± 0.24 and 18.78 ± 4.85 min respectively). Near misses more frequently received oxytocin treatment than the maternal deaths (OR 0.13; 95%CI 0.02-0.77). Magnesium sulfate treatment in severe-preeclampsia or eclampsia was less given in maternal deaths although insignificant statistically (OR 0.19; 95% CI 0.03-1.47). Prophylactic antibiotic was also more frequently given in near misses than in maternal deaths though insignificant statistically (OR 0.3; 95% CI 0.06-1.56). Extraneous variables, such as caesarean sections were less performed in maternal deaths (OR 0.15; 95% CI 0.04-0.51), vaginal deliveries were more frequent in maternal deaths (OR 3.47; 95% CI 1.05-11.54), and more women in near misses were referred from other health care facilities (OR 0.09; 95% CI 0.01-0.91). CONCLUSIONS: The near misses had relatively received better quality of care compared to the maternal deaths. The near misses had received faster response time and better treatments. Timely referral systems enabled benefits to prevent maternal death.


Asunto(s)
Servicios de Salud Materna/normas , Potencial Evento Adverso/normas , Complicaciones del Embarazo/mortalidad , Calidad de la Atención de Salud , Adulto , Femenino , Hospitales Públicos/métodos , Hospitales Públicos/normas , Hospitales de Enseñanza/métodos , Hospitales de Enseñanza/normas , Humanos , Indonesia , Muerte Materna/estadística & datos numéricos , Mortalidad Materna , Embarazo , Estudios Retrospectivos , Centros de Atención Terciaria/normas
6.
Reprod Biol Endocrinol ; 14(1): 53, 2016 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-27589950

RESUMEN

BACKGROUND: In Spanish public hospital Reproduction Units it is very problematic to perform programmed intrauterine insemination (IUI) on weekends, if indicated. Small previous pilot studies suggest that using a GnRH antagonist to avoid an LH weekend surge would allow to perform IUI on the following Monday, not impairing the expected pregnancy rate. METHODS: Between 1st January 2007 and 31st December 2015, 4.782 intrauterine inseminations were performed at Valladolid University Clinic, Spain, corresponding to 1.650 women. Of them, 911, corresponding to 695 women, should ideally have been performed during the weekend. If it happened that a member of the Reproduction Unit was on duty during that particular weekend, the standard protocol was not interrupted, and the IUI performed as planned (control group, 685 IUIs). If the former was not the case, the weekend gap was bridged by administering 0.25 mg GnRH antagonist (GnRHa). Ovulation was induced by means of 250 ug recombinant HCG (rHCG) 36 h prior to IUI on the following Monday (study group, 226 IUIs). RESULTS: There were no differences in the clinical pregnancy rate (13.7 cc vs. 16.2 %, p = 0.371) or in the ongoing pregnancy rate between groups (11.9 % vs. 14.9 %, p = 0.271). The multiple pregnancy rate was also comparable in both groups (14.7 % vs. 18.5 %, p = 0.77). CONCLUSIONS: Women with a planned IUI which cannot be performed at the ideal date can be offered postponement for two days with the support of GnRHa treatment, with results that are not inferior to those expected applying the regular protocol.


Asunto(s)
Hormona Liberadora de Gonadotropina/antagonistas & inhibidores , Antagonistas de Hormonas/farmacología , Hospitales Públicos/métodos , Inseminación Artificial/métodos , Índice de Embarazo , Adulto , Estudios de Cohortes , Femenino , Humanos , Proyectos Piloto , Embarazo , Índice de Embarazo/tendencias , Estudios Retrospectivos , España/epidemiología , Factores de Tiempo
7.
Intern Med J ; 46(1): 96-101, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26524217

RESUMEN

BACKGROUND: An anaemia clinic was established to improve the preoperative management of elective orthopaedic patients scheduled for arthroplasty. This paper is a report on the first 100 patients assessed. AIM: To assess the incidence and causes of anaemia in patients on a waiting list for elective arthroplasty in a public hospital and to assess the impact of anaemia detection in this patient population. METHODS: Patients attending an Anaemia Clinic for elective orthopaedic surgical patients, during March 2010 to June 2013 were studied. Outcome measures included change in haemoglobin preoperative results and perioperative transfusion rates by preoperative haemoglobin. RESULTS: Seventeen per cent of patients scheduled for elective surgery were found to be anaemic. Of the 100 patients who attended, approximately half were found to be iron deficient and the remainder had anaemia of chronic disease. Serum ferritin <30 µg/L alone did not identify iron deficiency in 80% of patients with iron deficiency. Patients with iron deficient anaemia were able to be treated, in all cases, to achieve a significant increase in preoperative haemoglobin. The general unavailability of erythropoietin limited effective intervention for the non-iron-deficient anaemic patients. Seven patients had their surgery cancelled because of the screening programme. CONCLUSIONS: Half of the anaemic patients in a joint replacement screening clinic were iron deficient, and treatment was effective in improving the pre-operative haemoglobin and reducing perioperative transfusion rates. This screening process should improve patient outcome. Another important finding in this group of patients is that ferritin levels cannot be reliably used as the sole indicator in the diagnosis of iron deficiency anaemia in this group of patients undergoing elective arthroplasty.


Asunto(s)
Anemia/sangre , Anemia/diagnóstico , Procedimientos Quirúrgicos Electivos/métodos , Hospitales Públicos/métodos , Procedimientos Ortopédicos/métodos , Cuidados Preoperatorios/métodos , Adulto , Anciano , Anciano de 80 o más Años , Anemia/terapia , Australia/epidemiología , Femenino , Humanos , Masculino , Persona de Mediana Edad
8.
BMC Anesthesiol ; 15: 136, 2015 Oct 07.
Artículo en Inglés | MEDLINE | ID: mdl-26445959

RESUMEN

BACKGROUND: Physiotherapy is integral to patient management in the Intensive Care Unit. The precise role that physiotherapists play in the critical care differs significantly worldwide. The aim of the study was to describe the profile of patients and the current patterns of physiotherapy services delivered for patients admitted in the five public hospital intensive care units in Zimbabwe. METHODS: A prospective record review was performed and records of all consecutive patients admitted into the five units during a two months period were included in the analysis. The data was collected using a checklist and the following were recorded for each patient: 1) demographic information, 2) admission diagnoses, 3) surgery classification, 4) method and time of mechanical ventilation 5) physiotherapy techniques and frequency and 6) the length of stay. RESULTS: A total of 137 patients were admitted to five units during the study. The mean age of patients in the study was 36.0 years (SD = 16.6). A mortality rate of 17.5 % was observed with most of the patients being below the age of 45 years. The majority of the patients, 61(45 %) had undergone emergency surgery and were in the ICU for postoperative treatment, whilst only 19(14 %) were in the units for clinical treatment (non-surgical). On admission, 72(52.6 %) of the patients were on mechanical ventilation. The mean duration on mechanical ventilation for patients was 4.0 days (SD =2.7) and a length of stay in the unit of 4.5 days (SD = 3.0). Of the patients who were admitted into the ICU 120 (87.6 %) had at least one session of physiotherapy treatment during their stay. The mean number of days physiotherapy treatment was received was 3.71 (SD = 3.14) days. The most commonly used physiotherapy techniques were active assisted limb movements (66.4 %), deep breathing exercises (65.0 %) and forced expiratory techniques (65.0 %). CONCLUSION: A young population admitted in the ICU for post-surgical treatment was observed across all hospital ICUs. The techniques which were executed in Zimbabwean ICUs showed that the goal of the physiotherapy treatment was mainly to prevent and treat respiratory complications and a culture of promoting bed rest still existed. TRIAL REGISTRATION: PACTR201408000829202.


Asunto(s)
Hospitales Públicos/métodos , Unidades de Cuidados Intensivos , Modalidades de Fisioterapia , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Estudios Transversales , Femenino , Hospitales Públicos/tendencias , Humanos , Unidades de Cuidados Intensivos/tendencias , Tiempo de Internación/tendencias , Masculino , Persona de Mediana Edad , Modalidades de Fisioterapia/tendencias , Estudios Prospectivos , Adulto Joven , Zimbabwe/epidemiología
9.
Ir Med J ; 108(7): 202-4, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26349348

RESUMEN

Laparoscopic cholecystectomy is a common procedure performed in both emergency and elective settings. Our aim was to analyse the trends in laparoscopic surgery in Ireland in the public and private healthcare systems. In particular we studied the trend in day case laparoscopic cholecystectomy. National HIPE data for the years 2010-2012 was obtained. Similar datasets were obtained from the three main health insurers. 19,214 laparoscopic cholecystectomies were carried out in Ireland over the 3-year period. More procedures were performed in the public system than the private system from 2010-2012. There was a steady increase in surgeries performed in the public sector, while the private sector remained static. Although the ALOS was significantly higher in the public sector, there was an increase in the rate of day case procedures from 416 (13%) to 762 (21.9%). The day case rates in private hospitals increased only slightly from 29 (5.1%) in 2010 to 40 (5.9%) in 2012. Day case laparoscopic cholecystectomy has been shown to be a safe procedure, however significant barriers remain in place to the implementation of successful day case units nationwide.


Asunto(s)
Actitud del Personal de Salud , Colecistectomía Laparoscópica , Cálculos Biliares/cirugía , Hospitales Privados/estadística & datos numéricos , Hospitales Públicos , Tiempo de Internación/tendencias , Colecistectomía Laparoscópica/métodos , Colecistectomía Laparoscópica/estadística & datos numéricos , Colecistectomía Laparoscópica/tendencias , Barreras de Comunicación , Hospitales Públicos/métodos , Hospitales Públicos/estadística & datos numéricos , Humanos , Seguro de Salud/estadística & datos numéricos , Irlanda , Evaluación de Resultado en la Atención de Salud , Estudios Retrospectivos , Ajuste de Riesgo
10.
Ann Emerg Med ; 61(6): 654-60, 2013 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22771203

RESUMEN

STUDY OBJECTIVE: We identify hospital-level factors from the administrative perspective that affect the availability and delivery of palliative care services in the emergency department (ED). METHODS: Semistructured interviews were conducted with 14 key informants, including hospital executives, ED directors, and palliative care directors at a tertiary care center, a public hospital, and a community hospital. The discussions were digitally recorded and transcribed to conduct a thematic analysis using grounded theory. A coding scheme was iteratively developed to subsequently identify themes and subthemes that emerged from the interviews. RESULTS: Barriers to integrating palliative care and emergency medicine from the administrative perspective include the ED culture of aggressive care, limited knowledge, palliative care staffing, and medicolegal concerns. Incentives to the delivery of palliative care in the ED from these key informants' perspective include improved patient and family satisfaction, opportunities to provide meaningful care to patients, decreased costs of care for admitted patients, and avoidance of unnecessary admissions to more intensive hospital settings, such as the ICU, for patients who have little likelihood of benefit. CONCLUSION: Though hospital administration at 3 urban hospitals on the East coast has great interest in integrating palliative care and emergency medicine to improve quality of care, patient and family satisfaction, and decrease length of stay for admitted patients, palliative care staffing, medicolegal concerns, and logistic issues need to be addressed.


Asunto(s)
Actitud del Personal de Salud , Servicio de Urgencia en Hospital , Administradores de Hospital , Cuidados Paliativos , Servicio de Urgencia en Hospital/legislación & jurisprudencia , Servicio de Urgencia en Hospital/organización & administración , Accesibilidad a los Servicios de Salud/organización & administración , Hospitales Comunitarios/métodos , Hospitales Comunitarios/organización & administración , Hospitales Públicos/métodos , Hospitales Públicos/organización & administración , Humanos , Entrevistas como Asunto , Cuidados Paliativos/legislación & jurisprudencia , Cuidados Paliativos/métodos , Cuidados Paliativos/organización & administración , Centros de Atención Terciaria/organización & administración , Estados Unidos
11.
Med Arch ; 67(2): 134-40, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-24341063

RESUMEN

INTRODUCTION: The purpose of this study was to investigate the impact of top management turnover on Strategic Collaborative Quality Management (SCQM) implementation in healthcare organizations. The role of top management turnover in the process and impact of the SCQM model was investigated using a case study of a public hospital. METHODS: Both qualitative and quantitative methods were used for data collection. RESULTS AND DISCUSSION: Top management turnover is a major threat to the long-term success of the SCQM intervention and makes it very difficult to sustain its benefits. Successful quality management implementation needs supportive and committed leadership and management. Top management stability encourages long-term planning and commitment to pursuing long-term objectives. CONCLUSION: This paper has highlighted the critical role of top management stability during the course of quality management implementation.


Asunto(s)
Eficiencia Organizacional , Organizaciones de Planificación en Salud , Gestión de la Calidad Total/organización & administración , Recolección de Datos , Hospitales Públicos/métodos , Hospitales Públicos/organización & administración , Humanos , Irán , Liderazgo , Modelos Organizacionales , Estudios de Casos Organizacionales , Cultura Organizacional , Reorganización del Personal , Evaluación de Programas y Proyectos de Salud , Mejoramiento de la Calidad
13.
J Gen Intern Med ; 25(10): 1123-8, 2010 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-20512531

RESUMEN

BACKGROUND: Poor communication between referring clinicians and specialists may lead to inefficient use of specialist services. San Francisco General Hospital implemented an electronic referral system (eReferral) that facilitates iterative pre-visit communication between referring and specialty clinicians to improve the referral process. OBJECTIVE: The purpose of the study was to determine the impact of eReferral (compared with paper-based referrals) on specialty referrals. DESIGN: The study was based on a visit-based questionnaire appended to new patient charts at randomly selected specialist clinic sessions before and after the implementation of eReferral. PARTICIPANTS: Specialty clinicians. MAIN MEASURES: The questionnaire focused on the self-reported difficulty in identifying referral question, referral appropriateness, need for and avoidability of follow-up visits. KEY RESULTS: We collected 505 questionnaires from speciality clinicians. It was difficult to identify the reason for referral in 19.8% of medical and 38.0% of surgical visits using paper-based methods vs. 11.0% and 9.5% of those using eReferral (p-value 0.03 and <0.001). Of those using eReferral, 6.4% and 9.8% of medical and surgical referrals using paper methods vs. 2.6% and 2.1% were deemed not completely appropriate (p-value 0.21 and 0.03). Follow-up was requested for 82.4% and 76.2% of medical and surgical patients with paper-based referrals vs. 90.1% and 58.1% of eReferrals (p-value 0.06 and 0.01). Follow-up was considered avoidable for 32.4% and 44.7% of medical and surgical follow-ups with paper-based methods vs. 27.5% and 13.5% with eReferral (0.41 and <0.001). CONCLUSION: Use of technology to promote standardized referral processes and iterative communication between referring clinicians and specialists has the potential to improve communication between primary care providers and specialists and to increase the effectiveness of specialty referrals.


Asunto(s)
Registros Electrónicos de Salud/normas , Accesibilidad a los Servicios de Salud/normas , Hospitales Públicos/normas , Medicina/normas , Hospitales Públicos/métodos , Humanos , Medicina/métodos , Derivación y Consulta , Encuestas y Cuestionarios/normas
14.
Intern Med J ; 40(11): 777-83, 2010 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-19811554

RESUMEN

AIMS: To determine whether in-hospital deaths of patients admitted through emergency departments with acute exacerbations of chronic obstructive pulmonary disease (COPD), acute myocardial infarction, intracerebral haemorrhage and acute hip fracture are increased by weekend versus weekday admission (the 'weekend effect'). METHODS: We performed a retrospective analysis of statewide administrative data from public hospitals in Queensland, Australia, during the 2002/2003-2006/2007 financial years. The primary outcome was 30-day in-hospital mortality. The secondary outcome of 2-day in-hospital mortality helped determine whether increased mortality of weekend admissions was closely linked to weekend medical care. RESULTS: During the study period, there were 30 522 COPD, 17 910 acute myocardial infarction, 4183 acute hip fracture and 1781 intracerebral haemorrhage admissions. There was no significant weekend effect on 30-day in-hospital mortality for COPD (adjusted risk ratio = 0.92, 95% CI: 0.81-1.04, P= 0.222), intracerebral haemorrhage (adjusted risk ratio = 1.01, 95% CI: 0.86-1.16, P= 0.935) or acute hip fracture (adjusted risk ratio = 0.78, 95% CI: 0.54-1.03, P= 0.13). There was a significant weekend effect for acute myocardial infarction (adjusted risk ratio = 1.15, 95% CI: 1.03-1.26, P= 0.007). Two-day in-hospital mortality showed similar results. CONCLUSION: This is the first Australian study on the 'weekend effect' (in a cohort other than neonates), and the first study worldwide to assess specifically the weekend effect among COPD patients. Observed patterns were consistent with overseas research. There was a significant weekend effect for myocardial infarction. Further research is needed to determine whether location (e.g. rural), clinical (e.g. disease severity) and service provision factors (e.g. access to invasive procedures) influence the weekend effect for acute medical conditions in Australia.


Asunto(s)
Mortalidad Hospitalaria/tendencias , Hospitales Públicos/normas , Hospitales Públicos/tendencias , Admisión del Paciente/normas , Admisión del Paciente/tendencias , Anciano , Anciano de 80 o más Años , Estudios de Cohortes , Bases de Datos Factuales/tendencias , Femenino , Hospitales Públicos/métodos , Humanos , Masculino , Queensland/epidemiología , Estudios Retrospectivos , Factores de Tiempo
15.
PLoS One ; 15(12): e0244171, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33370364

RESUMEN

INTRODUCTION: Peru is among the top ten countries with the highest number of coronavirus disease 2019 (COVID-19) cases worldwide. The aim of the study was to describe the clinical features of hospitalized adult patients with COVID-19 and to determine the prognostic factors associated with in-hospital mortality. METHODS: We conducted a retrospective cohort study among adult patients with COVID-19 admitted to Hospital Cayetano Heredia; a tertiary care hospital in Lima, Peru. The primary outcome was in-hospital mortality. Multivariate Cox proportional hazards regression was used to identify factors independently associated with in-hospital mortality. RESULTS: A total of 369 patients (median age 59 years [IQR:49-68]; 241 (65.31%) male) were included. Most patients (68.56%) reported at least one comorbidity; more frequently: obesity (42.55%), diabetes mellitus (21.95%), and hypertension (21.68%). The median duration of symptoms prior to hospital admission was 7 days (IQR: 5-10). Reported in-hospital mortality was 49.59%. By multiple Cox regression, oxygen saturation (SaO2) values of less than 90% on admission correlated with mortality, presenting 1.86 (95%CI: 1.02-3.39), 4.44 (95%CI: 2.46-8.02) and 7.74 (95%CI: 4.54-13.19) times greater risk of death for SaO2 of 89-85%, 84-80% and <80%, respectively, when compared to patients with SaO2 >90%. Additionally, age >60 years was associated with 1.88 times greater mortality. CONCLUSIONS: Oxygen saturation below 90% on admission is a strong predictor of in-hospital mortality in patients with COVID-19. In settings with limited resources, efforts to reduce mortality in COVID-19 should focus on early identification of hypoxemia and timely access to hospital care.


Asunto(s)
COVID-19/metabolismo , COVID-19/mortalidad , Oxígeno/metabolismo , Adulto , Anciano , Comorbilidad , Diabetes Mellitus/metabolismo , Diabetes Mellitus/mortalidad , Femenino , Mortalidad Hospitalaria , Hospitalización , Hospitales Públicos/métodos , Humanos , Hipertensión/metabolismo , Hipertensión/mortalidad , Masculino , Persona de Mediana Edad , Obesidad/metabolismo , Obesidad/mortalidad , Perú , Estudios Retrospectivos , Factores de Riesgo , SARS-CoV-2/patogenicidad
16.
Psychiatr Q ; 80(4): 219-31, 2009 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-19633958

RESUMEN

The American State Hospital has survived over 200 years. Society once viewed state hospitals as an absolute necessity and each state constructed numerous hospitals. Over time, the image of the state hospital as a means to cure the mentally ill changed drastically. The public perceived state hospitals as snake pits that warehoused the mentally ill and the state hospital was nearly destroyed. Nevertheless, the state hospital remains today with purposes similar to its ancestors and some that are very different. This paper examines the many influences that created the state hospital. Additionally, this paper addresses the Kirkbride Model, treatment methods and practices over time, and how the state hospital fell into disfavor as a means to treat the mentally ill. The paper concludes with comments on the mental health system today, in relation to the state hospital's role in treatment.


Asunto(s)
Hospitales Públicos/tendencias , Hospitales Provinciales/historia , Hospitales Provinciales/tendencias , Servicios de Salud Mental/historia , Servicios de Salud Mental/tendencias , Encuestas Epidemiológicas , Historia del Siglo XVIII , Historia del Siglo XIX , Historia del Siglo XX , Historia del Siglo XXI , Hospitales Públicos/historia , Hospitales Públicos/métodos , Hospitales Provinciales/estadística & datos numéricos , Humanos , Trastornos Mentales/historia , Trastornos Mentales/terapia
17.
S Afr J Commun Disord ; 66(1): e1-e14, 2019 Dec 02.
Artículo en Inglés | MEDLINE | ID: mdl-31793311

RESUMEN

BACKGROUND: Audiologists have a clinical and ethical responsibility to create a working environment, designed to reduce the potential for cross-contamination or transmission of infections. OBJECTIVES: To describe the infection prevention and control (IPC) measures utilised and the opinions of audiologists and speech therapists, and audiologists (A/STAs) towards IPC in public healthcare facilities in KwaZulu-Natal province, South Africa. METHOD: A quantitative, descriptive survey was utilised and entailed completing an online questionnaire. The Cronbach's alpha (0.82) indicated good internal consistency of the tool. Forty-nine A/STAs from 29 public healthcare facilities responded. RESULTS: Most participants (82%) followed a generic Department of Health policy on IPC, while 67% alluded to a discipline-specific policy. Participants had received training in infection control but indicated that further instruction was required for audiology-specific infection control procedures. Only 57% indicated that they 'sometimes' wore gloves with every patient during direct clinical contact. An association between the healthcare facility level and the wearing of gloves was found to be statistically significant (p = 0.025). Participants at regional and tertiary levels contended that gloves should be worn during most procedures versus those at district levels of care. While 96% washed their hands after each patient, only 76% washed their hands before each patient. Twenty-nine per cent indicated that they only 'sometimes' wore masks when in contact with patients with communicable diseases. Approximately one-third disinfected touch surfaces and toys, based on the clinician's discretion. The majority (86%) of participants, however, always followed the correct protocol for medical waste disposal. Despite training and the availability of policies, some practitioners displayed poor IPC practices in terms of universal precautions, personal protective equipment, handwashing and sterilisation. CONCLUSION: Further education, training and awareness related to appropriate IPC measures are recommended for audiologists. It is envisaged that this will lead to more effective IPC measures in audiology practice thereby reducing the risk of infection transmission.


Asunto(s)
Audiología/métodos , Infección Hospitalaria/prevención & control , Hospitales Públicos/métodos , Control de Infecciones/métodos , Adulto , Actitud del Personal de Salud , Audiología/educación , Femenino , Personal de Salud/educación , Política de Salud , Humanos , Masculino , Persona de Mediana Edad , Política Organizacional , Equipo de Protección Personal , Sudáfrica , Encuestas y Cuestionarios , Adulto Joven
18.
Br J Clin Pharmacol ; 65(2): 210-6, 2008 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-17662089

RESUMEN

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: The benefits of adverse drug reaction (ADR) monitoring are well-known. Poor awareness and nonavailability of a central co-ordinating body resulted in lack of ADR monitoring in India. The National Pharmacovigilance Programme was recently initiated, encouraging ADR monitoring in selected centres, including our centre. WHAT THIS STUDY ADDS: This is the first study of its kind at GHQH, Ootacamund that has provided insight into the burden of ADRs here. The incidence and severity of ADRs documented in our study is lower than those reported in comparable populations in Western studies but more than those reported in India. AIMS: To ascertain the current burden of ADRs at a Government hospital in Ooty and to assess the severity of reported ADRs and the additional financial burden associated with ADRs. METHODS: A prospective, spontaneous reporting study was conducted over a period of 9 months of inpatient admissions to the medical wards, co-ordinated by clinical pharmacists. The WHO definition of an ADR was adopted. The Naranjo algorithm scale was used for causality assessment. Confirmed ADRs were classified according to the Wills & Brown method and assessed for severity and patient outcomes. The average cost incurred in treating the ADRs was calculated. RESULTS: Of the total of 187 adverse drug events (ADEs) reported, 164 reports from 121 patients were confirmed as ADRs, giving an overall incidence of 9.8%. This included 58 (3.4%) ADR related admissions and 63 (3.7%) ADRs occurring during the hospital stay. About two thirds of the reactions (102, 62.2%) were classified as probable. The majority of the reactions (88, 53.7%) were mild. Most patients (119, 72.6%) recovered from the incidence. The majority of the reactions were of type H (100, 61%) which indicates that they were not predictable and not potentially preventable. An average cost of 481 rupees ( pound 6) was spent on each patient to manage ADRs. CONCLUSIONS: The incidence and severity of ADRs documented in our study are lower than those reported in comparable populations in Western studies but more than those reported in India.


Asunto(s)
Sistemas de Registro de Reacción Adversa a Medicamentos , Monitoreo de Drogas/métodos , Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos , Hospitales Públicos/métodos , Femenino , Humanos , India , Masculino , Estudios Prospectivos
19.
Intern Med J ; 37(6): 372-6, 2007 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-17535380

RESUMEN

BACKGROUND: In Australia medical practitioners are often required to assume the responsibility for assessing fitness to drive. However the clinical practice, knowledge and attitudes of doctors with regards to this responsibility are unknown. The aim of this study was to determine the clinical practice, knowledge and attitudes of public hospital doctors in the area of fitness-to-drive decision-making. METHODS: A survey of public hospital doctors in Adelaide, South Australia was undertaken in 2003, shortly after the promulgation nationwide of guidelines to assist in the assessment of patients' fitness to drive. The survey sought details on medical practitioners' clinical practice in this regard, as well as their knowledge of the guidelines. In addition, it sought their attitudes to undertake this responsibility. RESULTS: Eighty-four per cent of respondents had at some time in their working career at least discussed the issue of fitness to drive with their patients. Seventy per cent acknowledged that they had received the recently published guidelines on fitness to drive. Despite this, knowledge of the contents of the guidelines was poor. Attitudes to the responsibility were equivocal with several significant reservations expressed. CONCLUSION: Public hospital doctors in Australia have poor knowledge of the content of published guidelines in the area of fitness to drive. If this situation is to be improved, alternative approaches to the education of this group with respect to this significant public health problem should be considered. Many doctors are uncomfortable with their responsibilities in this area and alternative models of decision-making should be considered.


Asunto(s)
Actitud del Personal de Salud , Conducción de Automóvil/normas , Hospitales Públicos/métodos , Aptitud Física , Rol del Médico , Pensamiento , Adulto , Recolección de Datos/normas , Femenino , Hospitales Públicos/normas , Humanos , Masculino , Persona de Mediana Edad , Australia del Sur
20.
Artículo en Inglés | MEDLINE | ID: mdl-28352457

RESUMEN

Many types of organisation are difficult to change, mainly due to structural, cultural and contextual barriers. Change in public hospitals is arguably even more problematic than in other types of hospitals, due to features such as structural dysfunctionalities and bureaucracy stemming from being publicly-run institutions. The main goals of this commentary are to bring into focus and highlight the "3 + 3 Decision Framework" proposed by Edwards and Saltman. This aims to help guide policymakers and managers implementing productive change in public hospitals. However, while change from the top is popular, there are powerful front-line clinicians, especially doctors, who can act to counterbalance top-down efforts. Front-line clinicians have cultural characteristics and power that allows them to influence or reject managerial decisions. Clinicians in various lower-level roles can also influence other clinicians to resist or ignore management requirements. The context is further complicated by multi-stakeholder agendas, differing goals, and accumulated inertia. The special status of clinicians, along with other system features of public hospitals, should be factored into efforts to realise major system improvements and progressive change.


Asunto(s)
Hospitales Públicos/normas , Innovación Organizacional , Análisis de Sistemas , Técnicas de Apoyo para la Decisión , Hospitales Públicos/métodos , Hospitales Públicos/organización & administración , Humanos
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